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Network neighborhood for query Sequence : OST3B_HUMAN

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OST3B_HUMAN
SwissProt Accessions	Q9Y662	Gene names	HS3ST3B1, 3OST3B1, HS3ST3B
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

OST3B_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y662	Gene names	HS3ST3B1, 3OST3B1, HS3ST3B
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B).

OST3B_MOUSE
θ value	7.22167e-183 (rank : 2)	NC score	0.997337 (rank : 3)
Query Neighborhood Hits	51	Target Neighborhood Hits	42	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QZS6	Gene names	Hs3st3b1, 3ost3b1, Hs3st3b
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B).

OST3A_HUMAN
θ value	1.46868e-151 (rank : 3)	NC score	0.997791 (rank : 2)
Query Neighborhood Hits	51	Target Neighborhood Hits	34	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y663	Gene names	HS3ST3A1, 3OST3A1, HS3ST3A
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1) (h3-OST-3A).

OST3A_MOUSE
θ value	1.09172e-138 (rank : 4)	NC score	0.995922 (rank : 4)
Query Neighborhood Hits	51	Target Neighborhood Hits	38	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BKN6	Gene names	Hs3st3a1, 3ost3a1, Hs3st3a
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1).

OST4_HUMAN
θ value	1.87085e-122 (rank : 5)	NC score	0.987161 (rank : 9)
Query Neighborhood Hits	51	Target Neighborhood Hits	95	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

OST6_HUMAN
θ value	1.93603e-119 (rank : 6)	NC score	0.994378 (rank : 6)
Query Neighborhood Hits	51	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	Q96QI5, Q96RX7	Gene names	HS3ST6, HS3ST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (h3-OST-6).

OST6_MOUSE
θ value	2.79562e-118 (rank : 7)	NC score	0.994445 (rank : 5)
Query Neighborhood Hits	51	Target Neighborhood Hits	36	Shared Neighborhood Hits	29
SwissProt Accessions	Q5GFD5	Gene names	Hs3st6
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (3-OST-6).

OST2_HUMAN
θ value	1.81207e-117 (rank : 8)	NC score	0.992903 (rank : 7)
Query Neighborhood Hits	51	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y278	Gene names	HS3ST2, 3OST2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2) (h3-OST-2).

OST2_MOUSE
θ value	4.03687e-117 (rank : 9)	NC score	0.992196 (rank : 8)
Query Neighborhood Hits	51	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	Q673U1, Q8BLP1, Q8C055	Gene names	Hs3st2, 3ost2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2).

OST5_HUMAN
θ value	1.36269e-64 (rank : 10)	NC score	0.966870 (rank : 12)
Query Neighborhood Hits	51	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZT8, Q52LI2, Q8N285	Gene names	HS3ST5, 3OST5, HS3OST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5) (h3-OST-5).

OST5_MOUSE
θ value	1.36269e-64 (rank : 11)	NC score	0.966835 (rank : 13)
Query Neighborhood Hits	51	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BSL4	Gene names	Hs3st5, Hs3ost5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5).

OST1_HUMAN
θ value	6.55044e-59 (rank : 12)	NC score	0.966944 (rank : 10)
Query Neighborhood Hits	51	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	O14792, Q6PEY8	Gene names	HS3ST1, 3OST, 3OST1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1) (h3-OST-1).

OST1_MOUSE
θ value	4.24587e-58 (rank : 13)	NC score	0.966870 (rank : 11)
Query Neighborhood Hits	51	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	O35310	Gene names	Hs3st1, 3ost, 3ost1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1).

NDST3_HUMAN
θ value	1.85889e-29 (rank : 14)	NC score	0.759709 (rank : 14)
Query Neighborhood Hits	51	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	O95803, Q4W5C1, Q4W5D0, Q6UWC5, Q9UP21	Gene names	NDST3, HSST3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (hNDST-3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 3 (EC 2.8.2.-)].

NDST4_MOUSE
θ value	1.2049e-28 (rank : 15)	NC score	0.755551 (rank : 17)
Query Neighborhood Hits	51	Target Neighborhood Hits	33	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EQW8	Gene names	Ndst4, Hsst4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST3_MOUSE
θ value	1.57365e-28 (rank : 16)	NC score	0.754885 (rank : 18)
Query Neighborhood Hits	51	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EQH7, Q6AXE0, Q9D557	Gene names	Ndst3, Hsst3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 3 (EC 2.8.2.-)].

NDST4_HUMAN
θ value	3.50572e-28 (rank : 17)	NC score	0.757515 (rank : 15)
Query Neighborhood Hits	51	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H3R1	Gene names	NDST4, HSST4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST2_HUMAN
θ value	5.97985e-28 (rank : 18)	NC score	0.757022 (rank : 16)
Query Neighborhood Hits	51	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	P52849, Q2TB32, Q59H89	Gene names	NDST2, HSST2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 2 (EC 2.8.2.-)].

NDST2_MOUSE
θ value	7.80994e-28 (rank : 19)	NC score	0.754074 (rank : 19)
Query Neighborhood Hits	51	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	P52850, Q3UDF4, Q549P5	Gene names	Ndst2, Hsst2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) (Mndns) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)].

NDST1_HUMAN
θ value	5.06226e-27 (rank : 20)	NC score	0.743671 (rank : 20)
Query Neighborhood Hits	51	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	P52848, Q96E57	Gene names	NDST1, HSST, HSST1
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

NDST1_MOUSE
θ value	1.92365e-26 (rank : 21)	NC score	0.743084 (rank : 21)
Query Neighborhood Hits	51	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q3UHN9, O70353, Q3TBX3, Q3TDS3, Q8BZE5, Q9R206	Gene names	Ndst1
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

ST4S6_MOUSE
θ value	7.59969e-07 (rank : 22)	NC score	0.489089 (rank : 22)
Query Neighborhood Hits	51	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q91XQ5, Q80TW4, Q8BLQ5, Q9D2N6	Gene names	Galnac4s6st, Brag, Kiaa0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein).

ST4S6_HUMAN
θ value	1.69304e-06 (rank : 23)	NC score	0.470301 (rank : 23)
Query Neighborhood Hits	51	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q7LFX5, O60338, O60474, Q86VM4	Gene names	GALNAC4S6ST, BRAG, KIAA0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein) (hBRAG).

CNGB1_HUMAN
θ value	0.0193708 (rank : 24)	NC score	0.019135 (rank : 30)
Query Neighborhood Hits	51	Target Neighborhood Hits	222	Shared Neighborhood Hits	3
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

CHST7_HUMAN
θ value	0.365318 (rank : 25)	NC score	0.048742 (rank : 26)
Query Neighborhood Hits	51	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NS84, O75667	Gene names	CHST7
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 7 (EC 2.8.2.17) (EC 2.8.2.-) (Chondroitin 6-sulfotransferase 2) (C6ST-2) (N-acetylglucosamine 6-O- sulfotransferase 1) (GlcNAc6ST-4) (Galactose/N-acetylglucosamine/N- acetylglucosamine 6-O-sulfotransferase 5) (GST-5).

ST1C2_HUMAN
θ value	0.365318 (rank : 26)	NC score	0.041882 (rank : 29)
Query Neighborhood Hits	51	Target Neighborhood Hits	34	Shared Neighborhood Hits	11
SwissProt Accessions	O75897, Q53S63	Gene names	SULT1C2
Domain Architecture
Description	Sulfotransferase 1C2 (EC 2.8.2.-) (SULT1C) (SULT1C#2).

TPST2_MOUSE
θ value	0.47712 (rank : 27)	NC score	0.044493 (rank : 28)
Query Neighborhood Hits	51	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	O88856, Q8CBA8	Gene names	Tpst2, D5ucla3
Domain Architecture
Description	Protein-tyrosine sulfotransferase 2 (EC 2.8.2.20) (Tyrosylprotein sulfotransferase-2) (TPST-2).

ST2B1_MOUSE
θ value	0.62314 (rank : 28)	NC score	0.064273 (rank : 24)
Query Neighborhood Hits	51	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	O35400, Q8K472, Q91V03	Gene names	Sult2b1, Sult2b
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Sulfotransferase 2B) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

CHST7_MOUSE
θ value	1.06291 (rank : 29)	NC score	0.046151 (rank : 27)
Query Neighborhood Hits	51	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EP78, Q99NB0	Gene names	Chst7, Gst5
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 7 (EC 2.8.2.17) (EC 2.8.2.-) (Chondroitin 6-sulfotransferase 2) (C6ST-2) (mC6ST-2) (N- acetylglucosamine 6-O-sulfotransferase 1) (GlcNAc6ST-4) (Galactose/N- acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 5) (GST-5).

CRTC1_HUMAN
θ value	1.38821 (rank : 30)	NC score	0.015629 (rank : 31)
Query Neighborhood Hits	51	Target Neighborhood Hits	319	Shared Neighborhood Hits	8
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

ST2B1_HUMAN
θ value	1.38821 (rank : 31)	NC score	0.056429 (rank : 25)
Query Neighborhood Hits	51	Target Neighborhood Hits	57	Shared Neighborhood Hits	14
SwissProt Accessions	O00204, O00205, O75814	Gene names	SULT2B1, HSST2
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

SON_HUMAN
θ value	1.81305 (rank : 32)	NC score	0.006816 (rank : 42)
Query Neighborhood Hits	51	Target Neighborhood Hits	1568	Shared Neighborhood Hits	16
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

DOK3_HUMAN
θ value	3.0926 (rank : 33)	NC score	0.012552 (rank : 33)
Query Neighborhood Hits	51	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q7L591, Q8N864, Q9BQB3, Q9H666	Gene names	DOK3
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3).

PRR12_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.011879 (rank : 34)
Query Neighborhood Hits	51	Target Neighborhood Hits	460	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

EAF1_HUMAN
θ value	5.27518 (rank : 35)	NC score	0.008766 (rank : 38)
Query Neighborhood Hits	51	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q96JC9, Q8IW10	Gene names	EAF1
Domain Architecture	No domain graphic available
Description	ELL-associated factor 1.

FGD1_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.002698 (rank : 46)
Query Neighborhood Hits	51	Target Neighborhood Hits	367	Shared Neighborhood Hits	6
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

BTBDC_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.008659 (rank : 39)
Query Neighborhood Hits	51	Target Neighborhood Hits	248	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

KTNB1_MOUSE
θ value	6.88961 (rank : 38)	NC score	-0.000158 (rank : 50)
Query Neighborhood Hits	51	Target Neighborhood Hits	356	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BG40, Q8CD18, Q8R1J0, Q9CWV2	Gene names	Katnb1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

LIX1L_MOUSE
θ value	6.88961 (rank : 39)	NC score	0.007087 (rank : 41)
Query Neighborhood Hits	51	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BQ89	Gene names	Lix1l
Domain Architecture	No domain graphic available
Description	LIX1-like protein.

MYO15_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.001271 (rank : 47)
Query Neighborhood Hits	51	Target Neighborhood Hits	671	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NEK9_HUMAN
θ value	6.88961 (rank : 41)	NC score	-0.003653 (rank : 51)
Query Neighborhood Hits	51	Target Neighborhood Hits	900	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TD19, Q52LK6, Q8NCN0, Q8TCY4, Q9UPI4, Q9Y6S4, Q9Y6S5, Q9Y6S6	Gene names	NEK9, KIAA1995, NEK8, NERCC
Domain Architecture
Description	Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8).

RTN4_MOUSE
θ value	6.88961 (rank : 42)	NC score	0.004739 (rank : 44)
Query Neighborhood Hits	51	Target Neighborhood Hits	341	Shared Neighborhood Hits	4
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

RUSC2_MOUSE
θ value	6.88961 (rank : 43)	NC score	0.005525 (rank : 43)
Query Neighborhood Hits	51	Target Neighborhood Hits	305	Shared Neighborhood Hits	3
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SOX30_MOUSE
θ value	6.88961 (rank : 44)	NC score	0.004004 (rank : 45)
Query Neighborhood Hits	51	Target Neighborhood Hits	374	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

SRRM2_HUMAN
θ value	6.88961 (rank : 45)	NC score	0.000740 (rank : 49)
Query Neighborhood Hits	51	Target Neighborhood Hits	1296	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ST1A1_MOUSE
θ value	6.88961 (rank : 46)	NC score	0.014846 (rank : 32)
Query Neighborhood Hits	51	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	P52840	Gene names	Sult1a1, St1a1, Stp, Stp1
Domain Architecture	No domain graphic available
Description	Sulfotransferase 1A1 (EC 2.8.2.1) (Aryl sulfotransferase) (Phenol sulfotransferase) (Sulfokinase) (Phenol/aryl sulfotransferase) (mSTp1) (ST1A4).

ZCHC8_MOUSE
θ value	6.88961 (rank : 47)	NC score	0.008123 (rank : 40)
Query Neighborhood Hits	51	Target Neighborhood Hits	134	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CYA6, Q3TK71, Q8CCB7, Q91WQ1	Gene names	Zcchc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 8.

SAM14_HUMAN
θ value	8.99809 (rank : 48)	NC score	0.009643 (rank : 36)
Query Neighborhood Hits	51	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

SGIP1_HUMAN
θ value	8.99809 (rank : 49)	NC score	0.009371 (rank : 37)
Query Neighborhood Hits	51	Target Neighborhood Hits	198	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SGIP1_MOUSE
θ value	8.99809 (rank : 50)	NC score	0.009796 (rank : 35)
Query Neighborhood Hits	51	Target Neighborhood Hits	180	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SMCA4_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.000853 (rank : 48)
Query Neighborhood Hits	51	Target Neighborhood Hits	597	Shared Neighborhood Hits	6
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

Hits sorted by NC score

OST3B_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y662	Gene names	HS3ST3B1, 3OST3B1, HS3ST3B
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B).

OST3A_HUMAN
NC score	0.997791 (rank : 2)	θ value	1.46868e-151 (rank : 3)
Query Neighborhood Hits	51	Target Neighborhood Hits	34	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y663	Gene names	HS3ST3A1, 3OST3A1, HS3ST3A
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1) (h3-OST-3A).

OST3B_MOUSE
NC score	0.997337 (rank : 3)	θ value	7.22167e-183 (rank : 2)
Query Neighborhood Hits	51	Target Neighborhood Hits	42	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QZS6	Gene names	Hs3st3b1, 3ost3b1, Hs3st3b
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B).

OST3A_MOUSE
NC score	0.995922 (rank : 4)	θ value	1.09172e-138 (rank : 4)
Query Neighborhood Hits	51	Target Neighborhood Hits	38	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BKN6	Gene names	Hs3st3a1, 3ost3a1, Hs3st3a
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1).

OST6_MOUSE
NC score	0.994445 (rank : 5)	θ value	2.79562e-118 (rank : 7)
Query Neighborhood Hits	51	Target Neighborhood Hits	36	Shared Neighborhood Hits	29
SwissProt Accessions	Q5GFD5	Gene names	Hs3st6
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (3-OST-6).

OST6_HUMAN
NC score	0.994378 (rank : 6)	θ value	1.93603e-119 (rank : 6)
Query Neighborhood Hits	51	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	Q96QI5, Q96RX7	Gene names	HS3ST6, HS3ST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (h3-OST-6).

OST2_HUMAN
NC score	0.992903 (rank : 7)	θ value	1.81207e-117 (rank : 8)
Query Neighborhood Hits	51	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y278	Gene names	HS3ST2, 3OST2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2) (h3-OST-2).

OST2_MOUSE
NC score	0.992196 (rank : 8)	θ value	4.03687e-117 (rank : 9)
Query Neighborhood Hits	51	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	Q673U1, Q8BLP1, Q8C055	Gene names	Hs3st2, 3ost2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2).

OST4_HUMAN
NC score	0.987161 (rank : 9)	θ value	1.87085e-122 (rank : 5)
Query Neighborhood Hits	51	Target Neighborhood Hits	95	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

OST1_HUMAN
NC score	0.966944 (rank : 10)	θ value	6.55044e-59 (rank : 12)
Query Neighborhood Hits	51	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	O14792, Q6PEY8	Gene names	HS3ST1, 3OST, 3OST1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1) (h3-OST-1).

OST1_MOUSE
NC score	0.966870 (rank : 11)	θ value	4.24587e-58 (rank : 13)
Query Neighborhood Hits	51	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	O35310	Gene names	Hs3st1, 3ost, 3ost1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1).

OST5_HUMAN
NC score	0.966870 (rank : 12)	θ value	1.36269e-64 (rank : 10)
Query Neighborhood Hits	51	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZT8, Q52LI2, Q8N285	Gene names	HS3ST5, 3OST5, HS3OST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5) (h3-OST-5).

OST5_MOUSE
NC score	0.966835 (rank : 13)	θ value	1.36269e-64 (rank : 11)
Query Neighborhood Hits	51	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BSL4	Gene names	Hs3st5, Hs3ost5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5).

NDST3_HUMAN
NC score	0.759709 (rank : 14)	θ value	1.85889e-29 (rank : 14)
Query Neighborhood Hits	51	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	O95803, Q4W5C1, Q4W5D0, Q6UWC5, Q9UP21	Gene names	NDST3, HSST3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (hNDST-3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 3 (EC 2.8.2.-)].

NDST4_HUMAN
NC score	0.757515 (rank : 15)	θ value	3.50572e-28 (rank : 17)
Query Neighborhood Hits	51	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H3R1	Gene names	NDST4, HSST4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST2_HUMAN
NC score	0.757022 (rank : 16)	θ value	5.97985e-28 (rank : 18)
Query Neighborhood Hits	51	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	P52849, Q2TB32, Q59H89	Gene names	NDST2, HSST2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 2 (EC 2.8.2.-)].

NDST4_MOUSE
NC score	0.755551 (rank : 17)	θ value	1.2049e-28 (rank : 15)
Query Neighborhood Hits	51	Target Neighborhood Hits	33	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EQW8	Gene names	Ndst4, Hsst4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST3_MOUSE
NC score	0.754885 (rank : 18)	θ value	1.57365e-28 (rank : 16)
Query Neighborhood Hits	51	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EQH7, Q6AXE0, Q9D557	Gene names	Ndst3, Hsst3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 3 (EC 2.8.2.-)].

NDST2_MOUSE
NC score	0.754074 (rank : 19)	θ value	7.80994e-28 (rank : 19)
Query Neighborhood Hits	51	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	P52850, Q3UDF4, Q549P5	Gene names	Ndst2, Hsst2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) (Mndns) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)].

NDST1_HUMAN
NC score	0.743671 (rank : 20)	θ value	5.06226e-27 (rank : 20)
Query Neighborhood Hits	51	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	P52848, Q96E57	Gene names	NDST1, HSST, HSST1
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

NDST1_MOUSE
NC score	0.743084 (rank : 21)	θ value	1.92365e-26 (rank : 21)
Query Neighborhood Hits	51	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q3UHN9, O70353, Q3TBX3, Q3TDS3, Q8BZE5, Q9R206	Gene names	Ndst1
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

ST4S6_MOUSE
NC score	0.489089 (rank : 22)	θ value	7.59969e-07 (rank : 22)
Query Neighborhood Hits	51	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q91XQ5, Q80TW4, Q8BLQ5, Q9D2N6	Gene names	Galnac4s6st, Brag, Kiaa0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein).

ST4S6_HUMAN
NC score	0.470301 (rank : 23)	θ value	1.69304e-06 (rank : 23)
Query Neighborhood Hits	51	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q7LFX5, O60338, O60474, Q86VM4	Gene names	GALNAC4S6ST, BRAG, KIAA0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein) (hBRAG).

ST2B1_MOUSE
NC score	0.064273 (rank : 24)	θ value	0.62314 (rank : 28)
Query Neighborhood Hits	51	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	O35400, Q8K472, Q91V03	Gene names	Sult2b1, Sult2b
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Sulfotransferase 2B) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

ST2B1_HUMAN
NC score	0.056429 (rank : 25)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	51	Target Neighborhood Hits	57	Shared Neighborhood Hits	14
SwissProt Accessions	O00204, O00205, O75814	Gene names	SULT2B1, HSST2
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

CHST7_HUMAN
NC score	0.048742 (rank : 26)	θ value	0.365318 (rank : 25)
Query Neighborhood Hits	51	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NS84, O75667	Gene names	CHST7
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 7 (EC 2.8.2.17) (EC 2.8.2.-) (Chondroitin 6-sulfotransferase 2) (C6ST-2) (N-acetylglucosamine 6-O- sulfotransferase 1) (GlcNAc6ST-4) (Galactose/N-acetylglucosamine/N- acetylglucosamine 6-O-sulfotransferase 5) (GST-5).

CHST7_MOUSE
NC score	0.046151 (rank : 27)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	51	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EP78, Q99NB0	Gene names	Chst7, Gst5
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 7 (EC 2.8.2.17) (EC 2.8.2.-) (Chondroitin 6-sulfotransferase 2) (C6ST-2) (mC6ST-2) (N- acetylglucosamine 6-O-sulfotransferase 1) (GlcNAc6ST-4) (Galactose/N- acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 5) (GST-5).

TPST2_MOUSE
NC score	0.044493 (rank : 28)	θ value	0.47712 (rank : 27)
Query Neighborhood Hits	51	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	O88856, Q8CBA8	Gene names	Tpst2, D5ucla3
Domain Architecture
Description	Protein-tyrosine sulfotransferase 2 (EC 2.8.2.20) (Tyrosylprotein sulfotransferase-2) (TPST-2).

ST1C2_HUMAN
NC score	0.041882 (rank : 29)	θ value	0.365318 (rank : 26)
Query Neighborhood Hits	51	Target Neighborhood Hits	34	Shared Neighborhood Hits	11
SwissProt Accessions	O75897, Q53S63	Gene names	SULT1C2
Domain Architecture
Description	Sulfotransferase 1C2 (EC 2.8.2.-) (SULT1C) (SULT1C#2).

CNGB1_HUMAN
NC score	0.019135 (rank : 30)	θ value	0.0193708 (rank : 24)
Query Neighborhood Hits	51	Target Neighborhood Hits	222	Shared Neighborhood Hits	3
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

CRTC1_HUMAN
NC score	0.015629 (rank : 31)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	51	Target Neighborhood Hits	319	Shared Neighborhood Hits	8
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

ST1A1_MOUSE
NC score	0.014846 (rank : 32)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	51	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	P52840	Gene names	Sult1a1, St1a1, Stp, Stp1
Domain Architecture	No domain graphic available
Description	Sulfotransferase 1A1 (EC 2.8.2.1) (Aryl sulfotransferase) (Phenol sulfotransferase) (Sulfokinase) (Phenol/aryl sulfotransferase) (mSTp1) (ST1A4).

DOK3_HUMAN
NC score	0.012552 (rank : 33)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	51	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q7L591, Q8N864, Q9BQB3, Q9H666	Gene names	DOK3
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3).

PRR12_HUMAN
NC score	0.011879 (rank : 34)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	51	Target Neighborhood Hits	460	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SGIP1_MOUSE
NC score	0.009796 (rank : 35)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	51	Target Neighborhood Hits	180	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SAM14_HUMAN
NC score	0.009643 (rank : 36)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	51	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

SGIP1_HUMAN
NC score	0.009371 (rank : 37)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	51	Target Neighborhood Hits	198	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

EAF1_HUMAN
NC score	0.008766 (rank : 38)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	51	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q96JC9, Q8IW10	Gene names	EAF1
Domain Architecture	No domain graphic available
Description	ELL-associated factor 1.

BTBDC_HUMAN
NC score	0.008659 (rank : 39)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	51	Target Neighborhood Hits	248	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

ZCHC8_MOUSE
NC score	0.008123 (rank : 40)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	51	Target Neighborhood Hits	134	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CYA6, Q3TK71, Q8CCB7, Q91WQ1	Gene names	Zcchc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 8.

LIX1L_MOUSE
NC score	0.007087 (rank : 41)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	51	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BQ89	Gene names	Lix1l
Domain Architecture	No domain graphic available
Description	LIX1-like protein.

SON_HUMAN
NC score	0.006816 (rank : 42)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	51	Target Neighborhood Hits	1568	Shared Neighborhood Hits	16
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

RUSC2_MOUSE
NC score	0.005525 (rank : 43)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	51	Target Neighborhood Hits	305	Shared Neighborhood Hits	3
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

RTN4_MOUSE
NC score	0.004739 (rank : 44)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	51	Target Neighborhood Hits	341	Shared Neighborhood Hits	4
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

SOX30_MOUSE
NC score	0.004004 (rank : 45)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	51	Target Neighborhood Hits	374	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

FGD1_HUMAN
NC score	0.002698 (rank : 46)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	51	Target Neighborhood Hits	367	Shared Neighborhood Hits	6
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

MYO15_HUMAN
NC score	0.001271 (rank : 47)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	51	Target Neighborhood Hits	671	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

SMCA4_HUMAN
NC score	0.000853 (rank : 48)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	51	Target Neighborhood Hits	597	Shared Neighborhood Hits	6
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SRRM2_HUMAN
NC score	0.000740 (rank : 49)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	51	Target Neighborhood Hits	1296	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

KTNB1_MOUSE
NC score	-0.000158 (rank : 50)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	51	Target Neighborhood Hits	356	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BG40, Q8CD18, Q8R1J0, Q9CWV2	Gene names	Katnb1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

NEK9_HUMAN
NC score	-0.003653 (rank : 51)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	51	Target Neighborhood Hits	900	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TD19, Q52LK6, Q8NCN0, Q8TCY4, Q9UPI4, Q9Y6S4, Q9Y6S5, Q9Y6S6	Gene names	NEK9, KIAA1995, NEK8, NERCC
Domain Architecture
Description	Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8).