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Network neighborhood for query Sequence : NDST2_HUMAN

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NDST2_HUMAN
SwissProt Accessions	P52849, Q2TB32, Q59H89	Gene names	NDST2, HSST2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 2 (EC 2.8.2.-)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NDST1_HUMAN
θ value	0 (rank : 1)	NC score	0.997673 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	P52848, Q96E57	Gene names	NDST1, HSST, HSST1
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

NDST1_MOUSE
θ value	0 (rank : 2)	NC score	0.997781 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q3UHN9, O70353, Q3TBX3, Q3TDS3, Q8BZE5, Q9R206	Gene names	Ndst1
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

NDST2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	P52849, Q2TB32, Q59H89	Gene names	NDST2, HSST2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 2 (EC 2.8.2.-)].

NDST2_MOUSE
θ value	0 (rank : 4)	NC score	0.999349 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	P52850, Q3UDF4, Q549P5	Gene names	Ndst2, Hsst2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) (Mndns) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)].

NDST3_HUMAN
θ value	0 (rank : 5)	NC score	0.997213 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	26
SwissProt Accessions	O95803, Q4W5C1, Q4W5D0, Q6UWC5, Q9UP21	Gene names	NDST3, HSST3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (hNDST-3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 3 (EC 2.8.2.-)].

NDST3_MOUSE
θ value	0 (rank : 6)	NC score	0.997382 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EQH7, Q6AXE0, Q9D557	Gene names	Ndst3, Hsst3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 3 (EC 2.8.2.-)].

NDST4_HUMAN
θ value	0 (rank : 7)	NC score	0.997156 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H3R1	Gene names	NDST4, HSST4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST4_MOUSE
θ value	0 (rank : 8)	NC score	0.997075 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	33	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EQW8	Gene names	Ndst4, Hsst4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

OST2_MOUSE
θ value	8.3442e-30 (rank : 9)	NC score	0.763120 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	Q673U1, Q8BLP1, Q8C055	Gene names	Hs3st2, 3ost2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2).

OST5_MOUSE
θ value	1.4233e-29 (rank : 10)	NC score	0.788558 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BSL4	Gene names	Hs3st5, Hs3ost5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5).

OST2_HUMAN
θ value	1.85889e-29 (rank : 11)	NC score	0.762825 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y278	Gene names	HS3ST2, 3OST2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2) (h3-OST-2).

OST5_HUMAN
θ value	1.85889e-29 (rank : 12)	NC score	0.788376 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZT8, Q52LI2, Q8N285	Gene names	HS3ST5, 3OST5, HS3OST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5) (h3-OST-5).

OST3A_MOUSE
θ value	5.40856e-29 (rank : 13)	NC score	0.760856 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BKN6	Gene names	Hs3st3a1, 3ost3a1, Hs3st3a
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1).

OST3B_MOUSE
θ value	5.40856e-29 (rank : 14)	NC score	0.758683 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	42	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QZS6	Gene names	Hs3st3b1, 3ost3b1, Hs3st3b
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B).

OST4_HUMAN
θ value	4.57862e-28 (rank : 15)	NC score	0.758491 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	95	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

OST1_MOUSE
θ value	5.97985e-28 (rank : 16)	NC score	0.786777 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	O35310	Gene names	Hs3st1, 3ost, 3ost1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1).

OST3B_HUMAN
θ value	5.97985e-28 (rank : 17)	NC score	0.757022 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	51	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y662	Gene names	HS3ST3B1, 3OST3B1, HS3ST3B
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B).

OST3A_HUMAN
θ value	1.33217e-27 (rank : 18)	NC score	0.759137 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y663	Gene names	HS3ST3A1, 3OST3A1, HS3ST3A
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1) (h3-OST-3A).

OST1_HUMAN
θ value	3.87602e-27 (rank : 19)	NC score	0.788538 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	O14792, Q6PEY8	Gene names	HS3ST1, 3OST, 3OST1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1) (h3-OST-1).

OST6_HUMAN
θ value	1.47289e-26 (rank : 20)	NC score	0.757338 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	Q96QI5, Q96RX7	Gene names	HS3ST6, HS3ST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (h3-OST-6).

OST6_MOUSE
θ value	1.24688e-25 (rank : 21)	NC score	0.754637 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	Q5GFD5	Gene names	Hs3st6
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (3-OST-6).

ST4S6_MOUSE
θ value	0.00020696 (rank : 22)	NC score	0.420720 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q91XQ5, Q80TW4, Q8BLQ5, Q9D2N6	Gene names	Galnac4s6st, Brag, Kiaa0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein).

ST4S6_HUMAN
θ value	0.000270298 (rank : 23)	NC score	0.410989 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q7LFX5, O60338, O60474, Q86VM4	Gene names	GALNAC4S6ST, BRAG, KIAA0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein) (hBRAG).

ST1C3_HUMAN
θ value	0.125558 (rank : 24)	NC score	0.050943 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	Q6IMI6, Q6IMI5	Gene names	SULT1C3
Domain Architecture	No domain graphic available
Description	Putative sulfotransferase 1C3 (EC 2.8.2.-).

CIC_HUMAN
θ value	0.279714 (rank : 25)	NC score	0.017696 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	992	Shared Neighborhood Hits	6
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

ST1A3_HUMAN
θ value	0.813845 (rank : 26)	NC score	0.042537 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	P50224, O95603, Q6ZWJ5	Gene names	SULT1A3, STM
Domain Architecture
Description	Monoamine-sulfating phenol sulfotransferase (EC 2.8.2.1) (Aryl sulfotransferase 1A3) (Sulfotransferase, monoamine-preferring) (M-PST) (Thermolabile phenol sulfotransferase) (TL-PST) (Placental estrogen sulfotransferase) (Catecholamine-sulfating phenol sulfotransferase) (HAST3).

RGS3_MOUSE
θ value	1.38821 (rank : 27)	NC score	0.004227 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	1621	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TECT1_MOUSE
θ value	2.36792 (rank : 28)	NC score	0.020708 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BZ64, Q3UMP0, Q8BUE2	Gene names	Tect1
Domain Architecture	No domain graphic available
Description	Tectonic-1 precursor.

NOTC2_MOUSE
θ value	3.0926 (rank : 29)	NC score	-0.000798 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	1069	Shared Neighborhood Hits	2
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PTPRU_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.001853 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	237	Shared Neighborhood Hits	2
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

CBPZ_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.003659 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q66K79, O00520, Q96MX2	Gene names	CPZ
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

ST4A1_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.033719 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BR01, O43728	Gene names	SULT4A1, SULTX3
Domain Architecture
Description	Sulfotransferase 4A1 (EC 2.8.2.-) (Brain sulfotransferase-like protein) (hBR-STL) (hBR-STL-1) (Nervous system sulfotransferase) (NST).

ST4A1_MOUSE
θ value	5.27518 (rank : 33)	NC score	0.016210 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	P63046, O88872, Q3TXY5, Q91XS5, Q9CWY7, Q9DC97	Gene names	Sult4a1, Sultx3
Domain Architecture	No domain graphic available
Description	Sulfotransferase 4A1 (EC 2.8.2.-) (Brain sulfotransferase-like protein) (mBR-STL) (Nervous system sulfotransferase) (NST).

GPDM_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.006455 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	101	Shared Neighborhood Hits	2
SwissProt Accessions	Q64521, Q61507	Gene names	Gpd2, Gdm1
Domain Architecture
Description	Glycerol-3-phosphate dehydrogenase, mitochondrial precursor (EC 1.1.99.5) (GPD-M) (GPDH-M).

CP2CT_MOUSE
θ value	8.99809 (rank : 35)	NC score	0.000258 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	Q64458, Q8WUN8	Gene names	Cyp2c29
Domain Architecture
Description	Cytochrome P450 2C29 (EC 1.14.14.1) (CYPIIC29) (P-450 MUT-2) (Aldehyde oxygenase).

SALL3_HUMAN
θ value	8.99809 (rank : 36)	NC score	-0.002447 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	1066	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

SMAD9_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.002525 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JIW5, Q8CFF9	Gene names	Smad9, Madh8, Madh9, Smad8
Domain Architecture
Description	Mothers against decapentaplegic homolog 9 (SMAD 9) (Mothers against DPP homolog 9) (Smad9) (Smad8).

Hits sorted by NC score

NDST2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	P52849, Q2TB32, Q59H89	Gene names	NDST2, HSST2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 2 (EC 2.8.2.-)].

NDST2_MOUSE
NC score	0.999349 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	P52850, Q3UDF4, Q549P5	Gene names	Ndst2, Hsst2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) (Mndns) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)].

NDST1_MOUSE
NC score	0.997781 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q3UHN9, O70353, Q3TBX3, Q3TDS3, Q8BZE5, Q9R206	Gene names	Ndst1
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

NDST1_HUMAN
NC score	0.997673 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	P52848, Q96E57	Gene names	NDST1, HSST, HSST1
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

NDST3_MOUSE
NC score	0.997382 (rank : 5)	θ value	0 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EQH7, Q6AXE0, Q9D557	Gene names	Ndst3, Hsst3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 3 (EC 2.8.2.-)].

NDST3_HUMAN
NC score	0.997213 (rank : 6)	θ value	0 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	26
SwissProt Accessions	O95803, Q4W5C1, Q4W5D0, Q6UWC5, Q9UP21	Gene names	NDST3, HSST3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (hNDST-3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 3 (EC 2.8.2.-)].

NDST4_HUMAN
NC score	0.997156 (rank : 7)	θ value	0 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H3R1	Gene names	NDST4, HSST4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST4_MOUSE
NC score	0.997075 (rank : 8)	θ value	0 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	33	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EQW8	Gene names	Ndst4, Hsst4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

OST5_MOUSE
NC score	0.788558 (rank : 9)	θ value	1.4233e-29 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BSL4	Gene names	Hs3st5, Hs3ost5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5).

OST1_HUMAN
NC score	0.788538 (rank : 10)	θ value	3.87602e-27 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	O14792, Q6PEY8	Gene names	HS3ST1, 3OST, 3OST1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1) (h3-OST-1).

OST5_HUMAN
NC score	0.788376 (rank : 11)	θ value	1.85889e-29 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZT8, Q52LI2, Q8N285	Gene names	HS3ST5, 3OST5, HS3OST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5) (h3-OST-5).

OST1_MOUSE
NC score	0.786777 (rank : 12)	θ value	5.97985e-28 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	O35310	Gene names	Hs3st1, 3ost, 3ost1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1).

OST2_MOUSE
NC score	0.763120 (rank : 13)	θ value	8.3442e-30 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	Q673U1, Q8BLP1, Q8C055	Gene names	Hs3st2, 3ost2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2).

OST2_HUMAN
NC score	0.762825 (rank : 14)	θ value	1.85889e-29 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y278	Gene names	HS3ST2, 3OST2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2) (h3-OST-2).

OST3A_MOUSE
NC score	0.760856 (rank : 15)	θ value	5.40856e-29 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BKN6	Gene names	Hs3st3a1, 3ost3a1, Hs3st3a
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1).

OST3A_HUMAN
NC score	0.759137 (rank : 16)	θ value	1.33217e-27 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y663	Gene names	HS3ST3A1, 3OST3A1, HS3ST3A
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1) (h3-OST-3A).

OST3B_MOUSE
NC score	0.758683 (rank : 17)	θ value	5.40856e-29 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	42	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QZS6	Gene names	Hs3st3b1, 3ost3b1, Hs3st3b
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B).

OST4_HUMAN
NC score	0.758491 (rank : 18)	θ value	4.57862e-28 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	95	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

OST6_HUMAN
NC score	0.757338 (rank : 19)	θ value	1.47289e-26 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	Q96QI5, Q96RX7	Gene names	HS3ST6, HS3ST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (h3-OST-6).

OST3B_HUMAN
NC score	0.757022 (rank : 20)	θ value	5.97985e-28 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	51	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y662	Gene names	HS3ST3B1, 3OST3B1, HS3ST3B
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B).

OST6_MOUSE
NC score	0.754637 (rank : 21)	θ value	1.24688e-25 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	Q5GFD5	Gene names	Hs3st6
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (3-OST-6).

ST4S6_MOUSE
NC score	0.420720 (rank : 22)	θ value	0.00020696 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q91XQ5, Q80TW4, Q8BLQ5, Q9D2N6	Gene names	Galnac4s6st, Brag, Kiaa0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein).

ST4S6_HUMAN
NC score	0.410989 (rank : 23)	θ value	0.000270298 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q7LFX5, O60338, O60474, Q86VM4	Gene names	GALNAC4S6ST, BRAG, KIAA0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein) (hBRAG).

ST1C3_HUMAN
NC score	0.050943 (rank : 24)	θ value	0.125558 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	Q6IMI6, Q6IMI5	Gene names	SULT1C3
Domain Architecture	No domain graphic available
Description	Putative sulfotransferase 1C3 (EC 2.8.2.-).

ST1A3_HUMAN
NC score	0.042537 (rank : 25)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	P50224, O95603, Q6ZWJ5	Gene names	SULT1A3, STM
Domain Architecture
Description	Monoamine-sulfating phenol sulfotransferase (EC 2.8.2.1) (Aryl sulfotransferase 1A3) (Sulfotransferase, monoamine-preferring) (M-PST) (Thermolabile phenol sulfotransferase) (TL-PST) (Placental estrogen sulfotransferase) (Catecholamine-sulfating phenol sulfotransferase) (HAST3).

ST4A1_HUMAN
NC score	0.033719 (rank : 26)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BR01, O43728	Gene names	SULT4A1, SULTX3
Domain Architecture
Description	Sulfotransferase 4A1 (EC 2.8.2.-) (Brain sulfotransferase-like protein) (hBR-STL) (hBR-STL-1) (Nervous system sulfotransferase) (NST).

TECT1_MOUSE
NC score	0.020708 (rank : 27)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BZ64, Q3UMP0, Q8BUE2	Gene names	Tect1
Domain Architecture	No domain graphic available
Description	Tectonic-1 precursor.

CIC_HUMAN
NC score	0.017696 (rank : 28)	θ value	0.279714 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	992	Shared Neighborhood Hits	6
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

ST4A1_MOUSE
NC score	0.016210 (rank : 29)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	P63046, O88872, Q3TXY5, Q91XS5, Q9CWY7, Q9DC97	Gene names	Sult4a1, Sultx3
Domain Architecture	No domain graphic available
Description	Sulfotransferase 4A1 (EC 2.8.2.-) (Brain sulfotransferase-like protein) (mBR-STL) (Nervous system sulfotransferase) (NST).

GPDM_MOUSE
NC score	0.006455 (rank : 30)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	101	Shared Neighborhood Hits	2
SwissProt Accessions	Q64521, Q61507	Gene names	Gpd2, Gdm1
Domain Architecture
Description	Glycerol-3-phosphate dehydrogenase, mitochondrial precursor (EC 1.1.99.5) (GPD-M) (GPDH-M).

RGS3_MOUSE
NC score	0.004227 (rank : 31)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	1621	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CBPZ_HUMAN
NC score	0.003659 (rank : 32)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q66K79, O00520, Q96MX2	Gene names	CPZ
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

SMAD9_MOUSE
NC score	0.002525 (rank : 33)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JIW5, Q8CFF9	Gene names	Smad9, Madh8, Madh9, Smad8
Domain Architecture
Description	Mothers against decapentaplegic homolog 9 (SMAD 9) (Mothers against DPP homolog 9) (Smad9) (Smad8).

PTPRU_HUMAN
NC score	0.001853 (rank : 34)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	237	Shared Neighborhood Hits	2
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

CP2CT_MOUSE
NC score	0.000258 (rank : 35)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	Q64458, Q8WUN8	Gene names	Cyp2c29
Domain Architecture
Description	Cytochrome P450 2C29 (EC 1.14.14.1) (CYPIIC29) (P-450 MUT-2) (Aldehyde oxygenase).

NOTC2_MOUSE
NC score	-0.000798 (rank : 36)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	1069	Shared Neighborhood Hits	2
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

SALL3_HUMAN
NC score	-0.002447 (rank : 37)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	1066	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).