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Network neighborhood for query Sequence : SCNND_HUMAN

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SCNND_HUMAN
SwissProt Accessions	P51172, Q5T7L3, Q8NA24	Gene names	SCNN1D, DNACH
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit delta (Epithelial Na+ channel subunit delta) (Delta ENaC) (Nonvoltage-gated sodium channel 1 subunit delta) (SCNED) (Delta NaCH).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SCNND_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	P51172, Q5T7L3, Q8NA24	Gene names	SCNN1D, DNACH
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit delta (Epithelial Na+ channel subunit delta) (Delta ENaC) (Nonvoltage-gated sodium channel 1 subunit delta) (SCNED) (Delta NaCH).

SCNNA_MOUSE
θ value	2.52853e-119 (rank : 2)	NC score	0.976690 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	29	Shared Neighborhood Hits	15
SwissProt Accessions	Q61180, Q9WU37	Gene names	Scnn1a
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit alpha (Epithelial Na+ channel subunit alpha) (Alpha ENaC) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA) (Alpha NaCH).

SCNNA_HUMAN
θ value	1.2549e-118 (rank : 3)	NC score	0.977171 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	26	Shared Neighborhood Hits	15
SwissProt Accessions	P37088, O43271, Q9UM64	Gene names	SCNN1A, SCNN1
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit alpha (Epithelial Na+ channel subunit alpha) (Alpha ENaC) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA) (Alpha NaCH).

SCNNG_HUMAN
θ value	1.8332e-77 (rank : 4)	NC score	0.954792 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	24	Shared Neighborhood Hits	15
SwissProt Accessions	P51170, P78437, Q6PCC2, Q93023, Q93024, Q93025, Q93026, Q93027, Q96TD2	Gene names	SCNN1G
Domain Architecture
Description	Amiloride-sensitive sodium channel gamma-subunit (Epithelial Na+ channel subunit gamma) (Gamma ENaC) (Nonvoltage-gated sodium channel 1 subunit gamma) (SCNEG) (Gamma NaCH).

SCNNG_MOUSE
θ value	2.39424e-77 (rank : 5)	NC score	0.956772 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WU39	Gene names	Scnn1g
Domain Architecture
Description	Amiloride-sensitive sodium channel gamma-subunit (Epithelial Na+ channel subunit gamma) (Gamma ENaC) (Nonvoltage-gated sodium channel 1 subunit gamma) (SCNEG) (Gamma NaCH).

SCNNB_HUMAN
θ value	6.96618e-77 (rank : 6)	NC score	0.953145 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	15
SwissProt Accessions	P51168, O60891, Q96KG2, Q9UJ32, Q9UMU5	Gene names	SCNN1B
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit beta (Epithelial Na+ channel subunit beta) (Beta ENaC) (Nonvoltage-gated sodium channel 1 subunit beta) (SCNEB) (Beta NaCH) (ENaCB).

SCNNB_MOUSE
θ value	1.31376e-75 (rank : 7)	NC score	0.953326 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WU38	Gene names	Scnn1b
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit beta (Epithelial Na+ channel subunit beta) (Beta ENaC) (Nonvoltage-gated sodium channel 1 subunit beta) (SCNEB) (Beta NaCH).

ACCN4_HUMAN
θ value	7.30988e-26 (rank : 8)	NC score	0.781875 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	26	Shared Neighborhood Hits	15
SwissProt Accessions	Q96FT7, Q53SB7, Q6GMS1, Q6PIN9, Q9NQA4	Gene names	ACCN4, ASIC4
Domain Architecture	No domain graphic available
Description	Amiloride-sensitive cation channel 4 (Amiloride-sensitive cation channel 4, pituitary) (Acid-sensing ion channel 4).

ACCN4_MOUSE
θ value	9.54697e-26 (rank : 9)	NC score	0.787461 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	Q7TNS7, Q80XK4	Gene names	Accn4, Asic4
Domain Architecture	No domain graphic available
Description	Amiloride-sensitive cation channel 4 (Acid-sensing ion channel 4).

ACCN2_MOUSE
θ value	2.12685e-25 (rank : 10)	NC score	0.783756 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	Q6NXK8, Q50K97	Gene names	Accn2, Asic, Asic1, Bnac2
Domain Architecture	No domain graphic available
Description	Amiloride-sensitive cation channel 2, neuronal (Acid-sensing ion channel) (Acid-sensing ion channel 1) (Brain sodium channel 2).

ACCN2_HUMAN
θ value	3.62785e-25 (rank : 11)	NC score	0.780809 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	P78348, P78349, Q96CV2	Gene names	ACCN2, ASIC1, BNAC2
Domain Architecture
Description	Amiloride-sensitive cation channel 2, neuronal (Acid-sensing ion channel 1) (ASIC1) (Brain sodium channel 2) (BNaC2).

ACCN1_HUMAN
θ value	3.07116e-24 (rank : 12)	NC score	0.788816 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	18	Shared Neighborhood Hits	15
SwissProt Accessions	Q16515, Q13553, Q8N3E2	Gene names	ACCN1, ACCN, BNAC1, MDEG
Domain Architecture
Description	Amiloride-sensitive cation channel 1, neuronal (Amiloride-sensitive brain sodium channel) (Amiloride-sensitive cation channel neuronal 1) (Acid-sensing ion channel 2) (ASIC2) (Brain sodium channel 1) (BNaC1) (BNC1) (Mammalian degenerin homolog).

ACCN1_MOUSE
θ value	3.07116e-24 (rank : 13)	NC score	0.788536 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	18	Shared Neighborhood Hits	15
SwissProt Accessions	Q925H0, Q5SUU2, Q61203	Gene names	Accn1, Asic2, Bnac1
Domain Architecture
Description	Amiloride-sensitive cation channel 1, neuronal (Amiloride-sensitive brain sodium channel) (Acid-sensing ion channel 2) (Brain sodium channel 1) (BNaC1).

ACCN3_HUMAN
θ value	8.36355e-22 (rank : 14)	NC score	0.779050 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UHC3, O60263, O75906, Q59FN9, Q9UER8, Q9UHC4	Gene names	ACCN3, ASIC3, SLNAC1, TNAC1
Domain Architecture	No domain graphic available
Description	Amiloride-sensitive cation channel 3 (Acid-sensing ion channel 3) (ASIC3) (hASIC3) (Testis sodium channel 1) (hTNaC1).

ACCN3_MOUSE
θ value	3.17815e-21 (rank : 15)	NC score	0.773701 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	Q6X1Y6, Q7TQH4	Gene names	Accn3, Asic3, Drasic
Domain Architecture	No domain graphic available
Description	Amiloride-sensitive cation channel 3 (Acid-sensing ion channel 3) (ASIC3) (Dorsal root ASIC) (DRASIC).

ZBTB3_HUMAN
θ value	0.21417 (rank : 16)	NC score	0.008255 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	910	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

SFPQ_MOUSE
θ value	0.47712 (rank : 17)	NC score	0.013935 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	958	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SOX17_MOUSE
θ value	0.62314 (rank : 18)	NC score	0.014202 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	223	Shared Neighborhood Hits	6
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

CABIN_HUMAN
θ value	1.06291 (rank : 19)	NC score	0.027625 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	490	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CABL1_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.016820 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TDN4, Q8N3Y8, Q8NA22, Q9BTG1	Gene names	CABLES1, CABLES
Domain Architecture	No domain graphic available
Description	CDK5 and ABL1 enzyme substrate 1 (Interactor with CDK3 1) (Ik3-1).

CS007_MOUSE
θ value	3.0926 (rank : 21)	NC score	0.012278 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	464	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

DUX4_HUMAN
θ value	3.0926 (rank : 22)	NC score	0.006536 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	403	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBX2	Gene names	DUX4, DUX10
Domain Architecture	No domain graphic available
Description	Double homeobox protein 4 (Double homeobox protein 10) (Double homeobox protein 4/10).

ICAM5_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.006757 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	276	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

PKHA6_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.010289 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	591	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PRP2_MOUSE
θ value	3.0926 (rank : 25)	NC score	0.011137 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	347	Shared Neighborhood Hits	7
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

SDC1_HUMAN
θ value	3.0926 (rank : 26)	NC score	0.020277 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	P18827, Q96HB7	Gene names	SDC1, SDC
Domain Architecture
Description	Syndecan-1 precursor (SYND1) (CD138 antigen).

WDR33_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.002953 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	638	Shared Neighborhood Hits	5
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

CD2_HUMAN
θ value	6.88961 (rank : 28)	NC score	0.012893 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	504	Shared Neighborhood Hits	10
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

KCNC3_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.003399 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	256	Shared Neighborhood Hits	4
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

PAK7_HUMAN
θ value	6.88961 (rank : 30)	NC score	-0.001359 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	875	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P286, Q5W115, Q9BX09, Q9ULF6	Gene names	PAK7, KIAA1264, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (PAK-5).

PAK7_MOUSE
θ value	6.88961 (rank : 31)	NC score	-0.001312 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	875	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C015, Q3TQJ7, Q6RWS7	Gene names	Pak7, Pak5
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (p21-activated kinase 5).

RIMB1_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.002874 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	1479	Shared Neighborhood Hits	8
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SHAN1_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.002417 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	1041	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SREC2_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.001616 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	605	Shared Neighborhood Hits	4
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

ZN394_HUMAN
θ value	6.88961 (rank : 35)	NC score	-0.001838 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	752	Shared Neighborhood Hits	4
SwissProt Accessions	Q53GI3, Q6P5X9, Q8TB27, Q9HA37	Gene names	ZNF394
Domain Architecture	No domain graphic available
Description	Zinc finger protein 394.

CIC_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.006153 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	992	Shared Neighborhood Hits	14
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

HNF3G_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.002080 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	122	Shared Neighborhood Hits	2
SwissProt Accessions	P55318, Q9UMW9	Gene names	FOXA3, HNF3G, TCF3G
Domain Architecture
Description	Hepatocyte nuclear factor 3-gamma (HNF-3G) (Forkhead box protein A3) (Fork head-related protein FKH H3).

NECP2_MOUSE
θ value	8.99809 (rank : 38)	NC score	0.008902 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D1J1, Q3U1M1, Q9CV41	Gene names	Necap2
Domain Architecture	No domain graphic available
Description	Adaptin ear-binding coat-associated protein 2 (NECAP-2).

SHC2_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.004863 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

WT1_MOUSE
θ value	8.99809 (rank : 40)	NC score	-0.001435 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	723	Shared Neighborhood Hits	4
SwissProt Accessions	P22561	Gene names	Wt1, Wt-1
Domain Architecture
Description	Wilms' tumor protein homolog.

Hits sorted by NC score

SCNND_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	P51172, Q5T7L3, Q8NA24	Gene names	SCNN1D, DNACH
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit delta (Epithelial Na+ channel subunit delta) (Delta ENaC) (Nonvoltage-gated sodium channel 1 subunit delta) (SCNED) (Delta NaCH).

SCNNA_HUMAN
NC score	0.977171 (rank : 2)	θ value	1.2549e-118 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	26	Shared Neighborhood Hits	15
SwissProt Accessions	P37088, O43271, Q9UM64	Gene names	SCNN1A, SCNN1
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit alpha (Epithelial Na+ channel subunit alpha) (Alpha ENaC) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA) (Alpha NaCH).

SCNNA_MOUSE
NC score	0.976690 (rank : 3)	θ value	2.52853e-119 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	29	Shared Neighborhood Hits	15
SwissProt Accessions	Q61180, Q9WU37	Gene names	Scnn1a
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit alpha (Epithelial Na+ channel subunit alpha) (Alpha ENaC) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA) (Alpha NaCH).

SCNNG_MOUSE
NC score	0.956772 (rank : 4)	θ value	2.39424e-77 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WU39	Gene names	Scnn1g
Domain Architecture
Description	Amiloride-sensitive sodium channel gamma-subunit (Epithelial Na+ channel subunit gamma) (Gamma ENaC) (Nonvoltage-gated sodium channel 1 subunit gamma) (SCNEG) (Gamma NaCH).

SCNNG_HUMAN
NC score	0.954792 (rank : 5)	θ value	1.8332e-77 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	24	Shared Neighborhood Hits	15
SwissProt Accessions	P51170, P78437, Q6PCC2, Q93023, Q93024, Q93025, Q93026, Q93027, Q96TD2	Gene names	SCNN1G
Domain Architecture
Description	Amiloride-sensitive sodium channel gamma-subunit (Epithelial Na+ channel subunit gamma) (Gamma ENaC) (Nonvoltage-gated sodium channel 1 subunit gamma) (SCNEG) (Gamma NaCH).

SCNNB_MOUSE
NC score	0.953326 (rank : 6)	θ value	1.31376e-75 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WU38	Gene names	Scnn1b
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit beta (Epithelial Na+ channel subunit beta) (Beta ENaC) (Nonvoltage-gated sodium channel 1 subunit beta) (SCNEB) (Beta NaCH).

SCNNB_HUMAN
NC score	0.953145 (rank : 7)	θ value	6.96618e-77 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	15
SwissProt Accessions	P51168, O60891, Q96KG2, Q9UJ32, Q9UMU5	Gene names	SCNN1B
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit beta (Epithelial Na+ channel subunit beta) (Beta ENaC) (Nonvoltage-gated sodium channel 1 subunit beta) (SCNEB) (Beta NaCH) (ENaCB).

ACCN1_HUMAN
NC score	0.788816 (rank : 8)	θ value	3.07116e-24 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	18	Shared Neighborhood Hits	15
SwissProt Accessions	Q16515, Q13553, Q8N3E2	Gene names	ACCN1, ACCN, BNAC1, MDEG
Domain Architecture
Description	Amiloride-sensitive cation channel 1, neuronal (Amiloride-sensitive brain sodium channel) (Amiloride-sensitive cation channel neuronal 1) (Acid-sensing ion channel 2) (ASIC2) (Brain sodium channel 1) (BNaC1) (BNC1) (Mammalian degenerin homolog).

ACCN1_MOUSE
NC score	0.788536 (rank : 9)	θ value	3.07116e-24 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	18	Shared Neighborhood Hits	15
SwissProt Accessions	Q925H0, Q5SUU2, Q61203	Gene names	Accn1, Asic2, Bnac1
Domain Architecture
Description	Amiloride-sensitive cation channel 1, neuronal (Amiloride-sensitive brain sodium channel) (Acid-sensing ion channel 2) (Brain sodium channel 1) (BNaC1).

ACCN4_MOUSE
NC score	0.787461 (rank : 10)	θ value	9.54697e-26 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	Q7TNS7, Q80XK4	Gene names	Accn4, Asic4
Domain Architecture	No domain graphic available
Description	Amiloride-sensitive cation channel 4 (Acid-sensing ion channel 4).

ACCN2_MOUSE
NC score	0.783756 (rank : 11)	θ value	2.12685e-25 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	Q6NXK8, Q50K97	Gene names	Accn2, Asic, Asic1, Bnac2
Domain Architecture	No domain graphic available
Description	Amiloride-sensitive cation channel 2, neuronal (Acid-sensing ion channel) (Acid-sensing ion channel 1) (Brain sodium channel 2).

ACCN4_HUMAN
NC score	0.781875 (rank : 12)	θ value	7.30988e-26 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	26	Shared Neighborhood Hits	15
SwissProt Accessions	Q96FT7, Q53SB7, Q6GMS1, Q6PIN9, Q9NQA4	Gene names	ACCN4, ASIC4
Domain Architecture	No domain graphic available
Description	Amiloride-sensitive cation channel 4 (Amiloride-sensitive cation channel 4, pituitary) (Acid-sensing ion channel 4).

ACCN2_HUMAN
NC score	0.780809 (rank : 13)	θ value	3.62785e-25 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	P78348, P78349, Q96CV2	Gene names	ACCN2, ASIC1, BNAC2
Domain Architecture
Description	Amiloride-sensitive cation channel 2, neuronal (Acid-sensing ion channel 1) (ASIC1) (Brain sodium channel 2) (BNaC2).

ACCN3_HUMAN
NC score	0.779050 (rank : 14)	θ value	8.36355e-22 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UHC3, O60263, O75906, Q59FN9, Q9UER8, Q9UHC4	Gene names	ACCN3, ASIC3, SLNAC1, TNAC1
Domain Architecture	No domain graphic available
Description	Amiloride-sensitive cation channel 3 (Acid-sensing ion channel 3) (ASIC3) (hASIC3) (Testis sodium channel 1) (hTNaC1).

ACCN3_MOUSE
NC score	0.773701 (rank : 15)	θ value	3.17815e-21 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	Q6X1Y6, Q7TQH4	Gene names	Accn3, Asic3, Drasic
Domain Architecture	No domain graphic available
Description	Amiloride-sensitive cation channel 3 (Acid-sensing ion channel 3) (ASIC3) (Dorsal root ASIC) (DRASIC).

CABIN_HUMAN
NC score	0.027625 (rank : 16)	θ value	1.06291 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	490	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

SDC1_HUMAN
NC score	0.020277 (rank : 17)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	P18827, Q96HB7	Gene names	SDC1, SDC
Domain Architecture
Description	Syndecan-1 precursor (SYND1) (CD138 antigen).

CABL1_HUMAN
NC score	0.016820 (rank : 18)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TDN4, Q8N3Y8, Q8NA22, Q9BTG1	Gene names	CABLES1, CABLES
Domain Architecture	No domain graphic available
Description	CDK5 and ABL1 enzyme substrate 1 (Interactor with CDK3 1) (Ik3-1).

SOX17_MOUSE
NC score	0.014202 (rank : 19)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	223	Shared Neighborhood Hits	6
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

SFPQ_MOUSE
NC score	0.013935 (rank : 20)	θ value	0.47712 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	958	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

CD2_HUMAN
NC score	0.012893 (rank : 21)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	504	Shared Neighborhood Hits	10
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CS007_MOUSE
NC score	0.012278 (rank : 22)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	464	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

PRP2_MOUSE
NC score	0.011137 (rank : 23)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	347	Shared Neighborhood Hits	7
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PKHA6_MOUSE
NC score	0.010289 (rank : 24)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	591	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

NECP2_MOUSE
NC score	0.008902 (rank : 25)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D1J1, Q3U1M1, Q9CV41	Gene names	Necap2
Domain Architecture	No domain graphic available
Description	Adaptin ear-binding coat-associated protein 2 (NECAP-2).

ZBTB3_HUMAN
NC score	0.008255 (rank : 26)	θ value	0.21417 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	910	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

ICAM5_HUMAN
NC score	0.006757 (rank : 27)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	276	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

DUX4_HUMAN
NC score	0.006536 (rank : 28)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	403	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBX2	Gene names	DUX4, DUX10
Domain Architecture	No domain graphic available
Description	Double homeobox protein 4 (Double homeobox protein 10) (Double homeobox protein 4/10).

CIC_HUMAN
NC score	0.006153 (rank : 29)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	992	Shared Neighborhood Hits	14
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SHC2_HUMAN
NC score	0.004863 (rank : 30)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

KCNC3_HUMAN
NC score	0.003399 (rank : 31)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	256	Shared Neighborhood Hits	4
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

WDR33_HUMAN
NC score	0.002953 (rank : 32)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	638	Shared Neighborhood Hits	5
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

RIMB1_HUMAN
NC score	0.002874 (rank : 33)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	1479	Shared Neighborhood Hits	8
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SHAN1_HUMAN
NC score	0.002417 (rank : 34)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	1041	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

HNF3G_HUMAN
NC score	0.002080 (rank : 35)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	122	Shared Neighborhood Hits	2
SwissProt Accessions	P55318, Q9UMW9	Gene names	FOXA3, HNF3G, TCF3G
Domain Architecture
Description	Hepatocyte nuclear factor 3-gamma (HNF-3G) (Forkhead box protein A3) (Fork head-related protein FKH H3).

SREC2_MOUSE
NC score	0.001616 (rank : 36)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	605	Shared Neighborhood Hits	4
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

PAK7_MOUSE
NC score	-0.001312 (rank : 37)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	875	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C015, Q3TQJ7, Q6RWS7	Gene names	Pak7, Pak5
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (p21-activated kinase 5).

PAK7_HUMAN
NC score	-0.001359 (rank : 38)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	875	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P286, Q5W115, Q9BX09, Q9ULF6	Gene names	PAK7, KIAA1264, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (PAK-5).

WT1_MOUSE
NC score	-0.001435 (rank : 39)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	723	Shared Neighborhood Hits	4
SwissProt Accessions	P22561	Gene names	Wt1, Wt-1
Domain Architecture
Description	Wilms' tumor protein homolog.

ZN394_HUMAN
NC score	-0.001838 (rank : 40)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	752	Shared Neighborhood Hits	4
SwissProt Accessions	Q53GI3, Q6P5X9, Q8TB27, Q9HA37	Gene names	ZNF394
Domain Architecture	No domain graphic available
Description	Zinc finger protein 394.