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Network neighborhood for query Sequence : UE1D1_HUMAN

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UE1D1_HUMAN
SwissProt Accessions	Q9GZZ9, Q96ST1	Gene names	UBE1DC1, UBA5
Domain Architecture	No domain graphic available
Description	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme) (Ubiquitin-activating enzyme 5) (ThiFP1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UE1D1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q9GZZ9, Q96ST1	Gene names	UBE1DC1, UBA5
Domain Architecture	No domain graphic available
Description	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme) (Ubiquitin-activating enzyme 5) (ThiFP1).

UE1D1_MOUSE
θ value	7.9845e-182 (rank : 2)	NC score	0.996681 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	16	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VE47, Q9CYD6	Gene names	Ube1dc1
Domain Architecture	No domain graphic available
Description	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme).

ULE1B_MOUSE
θ value	2.28291e-11 (rank : 3)	NC score	0.494484 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	56	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z1F9, Q8BVX9	Gene names	Uble1b, Sae2, Uba2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

MOCS3_HUMAN
θ value	4.45536e-07 (rank : 4)	NC score	0.502997 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	O95396	Gene names	MOCS3
Domain Architecture
Description	Molybdenum cofactor synthesis protein 3 (Molybdopterin synthase sulfurylase) (MPT synthase sulfurylase).

ULE1B_HUMAN
θ value	8.40245e-06 (rank : 5)	NC score	0.437992 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	31	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UBT2, O95605, Q9NTJ1, Q9UED2	Gene names	UBLE1B, SAE2, UBA2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

UBE1L_HUMAN
θ value	1.87187e-05 (rank : 6)	NC score	0.397457 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	P41226	Gene names	UBE1L, UBE2
Domain Architecture
Description	Ubiquitin-activating enzyme E1 homolog (D8).

UBE1_MOUSE
θ value	1.87187e-05 (rank : 7)	NC score	0.385127 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	Q02053, Q542H8	Gene names	Ube1x, Uba1, Ube1
Domain Architecture
Description	Ubiquitin-activating enzyme E1 1.

UBA3_MOUSE
θ value	5.44631e-05 (rank : 8)	NC score	0.415294 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C878, O88598, Q9D6B7	Gene names	Ube1c, Uba3
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (Ubiquitin- activating enzyme 3) (NEDD8-activating enzyme E1C) (Ubiquitin- activating enzyme E1C).

UBE1_HUMAN
θ value	5.44631e-05 (rank : 9)	NC score	0.380825 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	P22314, Q96E13	Gene names	UBE1
Domain Architecture
Description	Ubiquitin-activating enzyme E1 (A1S9 protein).

UBA3_HUMAN
θ value	7.1131e-05 (rank : 10)	NC score	0.413505 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TBC4, O76088, Q9NTU3	Gene names	UBE1C, UBA3
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (Ubiquitin- activating enzyme 3) (NEDD8-activating enzyme E1C) (Ubiquitin- activating enzyme E1C).

NIN_HUMAN
θ value	0.0563607 (rank : 11)	NC score	0.025397 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	1416	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

ULE1A_MOUSE
θ value	0.0961366 (rank : 12)	NC score	0.284600 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R1T2, Q3TWJ0, Q9CSW9	Gene names	Uble1a, Aos1, Sae1, Sua1, Ubl1a1
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1A (SUMO-1-activating enzyme subunit 1).

ULE1A_HUMAN
θ value	0.279714 (rank : 13)	NC score	0.275732 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UBE0, O95717, Q9P020	Gene names	UBLE1A, AOS1, SAE1, SUA1
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1A (SUMO-1-activating enzyme subunit 1).

NDE1_MOUSE
θ value	1.06291 (rank : 14)	NC score	0.024505 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	602	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CZA6, Q3UBS6, Q3UIC1, Q9ERR0	Gene names	Nde1, Nude
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE) (mNudE).

ULA1_MOUSE
θ value	3.0926 (rank : 15)	NC score	0.176413 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VBW6, Q8CFL6	Gene names	Appbp1
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 regulatory subunit (Amyloid protein-binding protein 1) (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1).

ULA1_HUMAN
θ value	4.03905 (rank : 16)	NC score	0.173813 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	Q13564	Gene names	APPBP1
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 regulatory subunit (Amyloid protein-binding protein 1) (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1) (Protooncogene protein 1) (HPP1).

ES8L2_MOUSE
θ value	5.27518 (rank : 17)	NC score	0.012693 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	169	Shared Neighborhood Hits	2
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

ABLM3_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.010868 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	293	Shared Neighborhood Hits	3
SwissProt Accessions	O94929, Q658S1, Q68CI5, Q9BV32	Gene names	ABLIM3, KIAA0843
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 3 (Actin-binding LIM protein family member 3) (abLIM-3).

ABLM3_MOUSE
θ value	6.88961 (rank : 19)	NC score	0.010822 (rank : 20)
Query Neighborhood Hits	19	Target Neighborhood Hits	294	Shared Neighborhood Hits	3
SwissProt Accessions	Q69ZX8, Q52KR1, Q6PAI7	Gene names	Ablim3, Kiaa0843
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 3 (Actin-binding LIM protein family member 3) (abLIM-3).

ATG7_MOUSE
θ value	θ > 10 (rank : 20)	NC score	0.050140 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	16	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D906, Q3TCD9, Q8K4Q5	Gene names	Atg7, Apg7l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 7 (APG7-like) (Ubiquitin-activating enzyme E1-like protein) (mAGP7).

Hits sorted by NC score

UE1D1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q9GZZ9, Q96ST1	Gene names	UBE1DC1, UBA5
Domain Architecture	No domain graphic available
Description	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme) (Ubiquitin-activating enzyme 5) (ThiFP1).

UE1D1_MOUSE
NC score	0.996681 (rank : 2)	θ value	7.9845e-182 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	16	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VE47, Q9CYD6	Gene names	Ube1dc1
Domain Architecture	No domain graphic available
Description	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme).

MOCS3_HUMAN
NC score	0.502997 (rank : 3)	θ value	4.45536e-07 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	O95396	Gene names	MOCS3
Domain Architecture
Description	Molybdenum cofactor synthesis protein 3 (Molybdopterin synthase sulfurylase) (MPT synthase sulfurylase).

ULE1B_MOUSE
NC score	0.494484 (rank : 4)	θ value	2.28291e-11 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	56	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z1F9, Q8BVX9	Gene names	Uble1b, Sae2, Uba2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

ULE1B_HUMAN
NC score	0.437992 (rank : 5)	θ value	8.40245e-06 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	31	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UBT2, O95605, Q9NTJ1, Q9UED2	Gene names	UBLE1B, SAE2, UBA2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

UBA3_MOUSE
NC score	0.415294 (rank : 6)	θ value	5.44631e-05 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C878, O88598, Q9D6B7	Gene names	Ube1c, Uba3
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (Ubiquitin- activating enzyme 3) (NEDD8-activating enzyme E1C) (Ubiquitin- activating enzyme E1C).

UBA3_HUMAN
NC score	0.413505 (rank : 7)	θ value	7.1131e-05 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TBC4, O76088, Q9NTU3	Gene names	UBE1C, UBA3
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (Ubiquitin- activating enzyme 3) (NEDD8-activating enzyme E1C) (Ubiquitin- activating enzyme E1C).

UBE1L_HUMAN
NC score	0.397457 (rank : 8)	θ value	1.87187e-05 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	P41226	Gene names	UBE1L, UBE2
Domain Architecture
Description	Ubiquitin-activating enzyme E1 homolog (D8).

UBE1_MOUSE
NC score	0.385127 (rank : 9)	θ value	1.87187e-05 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	Q02053, Q542H8	Gene names	Ube1x, Uba1, Ube1
Domain Architecture
Description	Ubiquitin-activating enzyme E1 1.

UBE1_HUMAN
NC score	0.380825 (rank : 10)	θ value	5.44631e-05 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	P22314, Q96E13	Gene names	UBE1
Domain Architecture
Description	Ubiquitin-activating enzyme E1 (A1S9 protein).

ULE1A_MOUSE
NC score	0.284600 (rank : 11)	θ value	0.0961366 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R1T2, Q3TWJ0, Q9CSW9	Gene names	Uble1a, Aos1, Sae1, Sua1, Ubl1a1
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1A (SUMO-1-activating enzyme subunit 1).

ULE1A_HUMAN
NC score	0.275732 (rank : 12)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UBE0, O95717, Q9P020	Gene names	UBLE1A, AOS1, SAE1, SUA1
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1A (SUMO-1-activating enzyme subunit 1).

ULA1_MOUSE
NC score	0.176413 (rank : 13)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VBW6, Q8CFL6	Gene names	Appbp1
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 regulatory subunit (Amyloid protein-binding protein 1) (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1).

ULA1_HUMAN
NC score	0.173813 (rank : 14)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	Q13564	Gene names	APPBP1
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 regulatory subunit (Amyloid protein-binding protein 1) (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1) (Protooncogene protein 1) (HPP1).

ATG7_MOUSE
NC score	0.050140 (rank : 15)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	19	Target Neighborhood Hits	16	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D906, Q3TCD9, Q8K4Q5	Gene names	Atg7, Apg7l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 7 (APG7-like) (Ubiquitin-activating enzyme E1-like protein) (mAGP7).

NIN_HUMAN
NC score	0.025397 (rank : 16)	θ value	0.0563607 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	1416	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

NDE1_MOUSE
NC score	0.024505 (rank : 17)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	602	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CZA6, Q3UBS6, Q3UIC1, Q9ERR0	Gene names	Nde1, Nude
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE) (mNudE).

ES8L2_MOUSE
NC score	0.012693 (rank : 18)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	169	Shared Neighborhood Hits	2
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

ABLM3_HUMAN
NC score	0.010868 (rank : 19)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	293	Shared Neighborhood Hits	3
SwissProt Accessions	O94929, Q658S1, Q68CI5, Q9BV32	Gene names	ABLIM3, KIAA0843
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 3 (Actin-binding LIM protein family member 3) (abLIM-3).

ABLM3_MOUSE
NC score	0.010822 (rank : 20)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	294	Shared Neighborhood Hits	3
SwissProt Accessions	Q69ZX8, Q52KR1, Q6PAI7	Gene names	Ablim3, Kiaa0843
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 3 (Actin-binding LIM protein family member 3) (abLIM-3).