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Network neighborhood for query Sequence : UBE1_MOUSE

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UBE1_MOUSE
SwissProt Accessions	Q02053, Q542H8	Gene names	Ube1x, Uba1, Ube1
Domain Architecture
Description	Ubiquitin-activating enzyme E1 1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UBE1L_HUMAN
θ value	0 (rank : 1)	NC score	0.979274 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	P41226	Gene names	UBE1L, UBE2
Domain Architecture
Description	Ubiquitin-activating enzyme E1 homolog (D8).

UBE1_HUMAN
θ value	0 (rank : 2)	NC score	0.999046 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	P22314, Q96E13	Gene names	UBE1
Domain Architecture
Description	Ubiquitin-activating enzyme E1 (A1S9 protein).

UBE1_MOUSE
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q02053, Q542H8	Gene names	Ube1x, Uba1, Ube1
Domain Architecture
Description	Ubiquitin-activating enzyme E1 1.

ULE1B_MOUSE
θ value	4.89182e-30 (rank : 4)	NC score	0.721015 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	56	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z1F9, Q8BVX9	Gene names	Uble1b, Sae2, Uba2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

ULE1B_HUMAN
θ value	2.68423e-28 (rank : 5)	NC score	0.718093 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	31	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UBT2, O95605, Q9NTJ1, Q9UED2	Gene names	UBLE1B, SAE2, UBA2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

UBA3_MOUSE
θ value	1.24688e-25 (rank : 6)	NC score	0.720611 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C878, O88598, Q9D6B7	Gene names	Ube1c, Uba3
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (Ubiquitin- activating enzyme 3) (NEDD8-activating enzyme E1C) (Ubiquitin- activating enzyme E1C).

UBA3_HUMAN
θ value	1.62847e-25 (rank : 7)	NC score	0.719818 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TBC4, O76088, Q9NTU3	Gene names	UBE1C, UBA3
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (Ubiquitin- activating enzyme 3) (NEDD8-activating enzyme E1C) (Ubiquitin- activating enzyme E1C).

ULE1A_HUMAN
θ value	1.37858e-24 (rank : 8)	NC score	0.732750 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UBE0, O95717, Q9P020	Gene names	UBLE1A, AOS1, SAE1, SUA1
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1A (SUMO-1-activating enzyme subunit 1).

ULE1A_MOUSE
θ value	3.39556e-23 (rank : 9)	NC score	0.728722 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R1T2, Q3TWJ0, Q9CSW9	Gene names	Uble1a, Aos1, Sae1, Sua1, Ubl1a1
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1A (SUMO-1-activating enzyme subunit 1).

ULA1_HUMAN
θ value	2.20605e-14 (rank : 10)	NC score	0.567151 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	Q13564	Gene names	APPBP1
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 regulatory subunit (Amyloid protein-binding protein 1) (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1) (Protooncogene protein 1) (HPP1).

ULA1_MOUSE
θ value	1.2105e-12 (rank : 11)	NC score	0.556430 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VBW6, Q8CFL6	Gene names	Appbp1
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 regulatory subunit (Amyloid protein-binding protein 1) (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1).

MOCS3_HUMAN
θ value	6.64225e-11 (rank : 12)	NC score	0.609982 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	O95396	Gene names	MOCS3
Domain Architecture
Description	Molybdenum cofactor synthesis protein 3 (Molybdopterin synthase sulfurylase) (MPT synthase sulfurylase).

UE1D1_HUMAN
θ value	1.87187e-05 (rank : 13)	NC score	0.385127 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	Q9GZZ9, Q96ST1	Gene names	UBE1DC1, UBA5
Domain Architecture	No domain graphic available
Description	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme) (Ubiquitin-activating enzyme 5) (ThiFP1).

UE1D1_MOUSE
θ value	4.1701e-05 (rank : 14)	NC score	0.381725 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VE47, Q9CYD6	Gene names	Ube1dc1
Domain Architecture	No domain graphic available
Description	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme).

GA6S_HUMAN
θ value	0.47712 (rank : 15)	NC score	0.022560 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P34059, Q86VK3	Gene names	GALNS
Domain Architecture
Description	N-acetylgalactosamine-6-sulfatase precursor (EC 3.1.6.4) (N- acetylgalactosamine-6-sulfate sulfatase) (Galactose-6-sulfate sulfatase) (GalNAc6S sulfatase) (Chondroitinsulfatase) (Chondroitinase).

ZBT7A_HUMAN
θ value	1.06291 (rank : 16)	NC score	0.004573 (rank : 23)
Query Neighborhood Hits	21	Target Neighborhood Hits	823	Shared Neighborhood Hits	3
SwissProt Accessions	O95365, O00456	Gene names	ZBTB7A, FBI1, LRF, ZBTB7
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma- related factor) (Factor that binds to inducer of short transcripts protein 1) (Factor binding IST protein 1) (FBI-1) (HIV-1 1st-binding protein 1) (TTF-I-interacting peptide 21) (TIP21).

CHD9_MOUSE
θ value	1.81305 (rank : 17)	NC score	0.010676 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	427	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

PDIA1_MOUSE
θ value	3.0926 (rank : 18)	NC score	0.011590 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	P09103	Gene names	P4hb, Pdia1
Domain Architecture
Description	Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) (Prolyl 4- hydroxylase subunit beta) (Cellular thyroid hormone-binding protein) (p55) (Erp59).

CHD9_HUMAN
θ value	8.99809 (rank : 19)	NC score	0.008239 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	343	Shared Neighborhood Hits	3
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CLAP2_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.007911 (rank : 22)
Query Neighborhood Hits	21	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BRT1, Q8CHE3, Q99JI3, Q9DB80	Gene names	Clasp2, Kiaa0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

SCEL_MOUSE
θ value	8.99809 (rank : 21)	NC score	0.010020 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EQG3, Q9CTT9	Gene names	Scel
Domain Architecture
Description	Sciellin.

ATG7_HUMAN
θ value	θ > 10 (rank : 22)	NC score	0.082666 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	O95352, Q7L8L0, Q9BWP2, Q9UFH4	Gene names	ATG7, APG7L
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 7 (APG7-like) (Ubiquitin-activating enzyme E1-like protein) (hAGP7).

ATG7_MOUSE
θ value	θ > 10 (rank : 23)	NC score	0.082187 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	16	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D906, Q3TCD9, Q8K4Q5	Gene names	Atg7, Apg7l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 7 (APG7-like) (Ubiquitin-activating enzyme E1-like protein) (mAGP7).

Hits sorted by NC score

UBE1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q02053, Q542H8	Gene names	Ube1x, Uba1, Ube1
Domain Architecture
Description	Ubiquitin-activating enzyme E1 1.

UBE1_HUMAN
NC score	0.999046 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	P22314, Q96E13	Gene names	UBE1
Domain Architecture
Description	Ubiquitin-activating enzyme E1 (A1S9 protein).

UBE1L_HUMAN
NC score	0.979274 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	P41226	Gene names	UBE1L, UBE2
Domain Architecture
Description	Ubiquitin-activating enzyme E1 homolog (D8).

ULE1A_HUMAN
NC score	0.732750 (rank : 4)	θ value	1.37858e-24 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UBE0, O95717, Q9P020	Gene names	UBLE1A, AOS1, SAE1, SUA1
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1A (SUMO-1-activating enzyme subunit 1).

ULE1A_MOUSE
NC score	0.728722 (rank : 5)	θ value	3.39556e-23 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R1T2, Q3TWJ0, Q9CSW9	Gene names	Uble1a, Aos1, Sae1, Sua1, Ubl1a1
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1A (SUMO-1-activating enzyme subunit 1).

ULE1B_MOUSE
NC score	0.721015 (rank : 6)	θ value	4.89182e-30 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	56	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z1F9, Q8BVX9	Gene names	Uble1b, Sae2, Uba2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

UBA3_MOUSE
NC score	0.720611 (rank : 7)	θ value	1.24688e-25 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C878, O88598, Q9D6B7	Gene names	Ube1c, Uba3
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (Ubiquitin- activating enzyme 3) (NEDD8-activating enzyme E1C) (Ubiquitin- activating enzyme E1C).

UBA3_HUMAN
NC score	0.719818 (rank : 8)	θ value	1.62847e-25 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TBC4, O76088, Q9NTU3	Gene names	UBE1C, UBA3
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (Ubiquitin- activating enzyme 3) (NEDD8-activating enzyme E1C) (Ubiquitin- activating enzyme E1C).

ULE1B_HUMAN
NC score	0.718093 (rank : 9)	θ value	2.68423e-28 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	31	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UBT2, O95605, Q9NTJ1, Q9UED2	Gene names	UBLE1B, SAE2, UBA2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

MOCS3_HUMAN
NC score	0.609982 (rank : 10)	θ value	6.64225e-11 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	O95396	Gene names	MOCS3
Domain Architecture
Description	Molybdenum cofactor synthesis protein 3 (Molybdopterin synthase sulfurylase) (MPT synthase sulfurylase).

ULA1_HUMAN
NC score	0.567151 (rank : 11)	θ value	2.20605e-14 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	Q13564	Gene names	APPBP1
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 regulatory subunit (Amyloid protein-binding protein 1) (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1) (Protooncogene protein 1) (HPP1).

ULA1_MOUSE
NC score	0.556430 (rank : 12)	θ value	1.2105e-12 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VBW6, Q8CFL6	Gene names	Appbp1
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 regulatory subunit (Amyloid protein-binding protein 1) (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1).

UE1D1_HUMAN
NC score	0.385127 (rank : 13)	θ value	1.87187e-05 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	Q9GZZ9, Q96ST1	Gene names	UBE1DC1, UBA5
Domain Architecture	No domain graphic available
Description	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme) (Ubiquitin-activating enzyme 5) (ThiFP1).

UE1D1_MOUSE
NC score	0.381725 (rank : 14)	θ value	4.1701e-05 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VE47, Q9CYD6	Gene names	Ube1dc1
Domain Architecture	No domain graphic available
Description	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme).

ATG7_HUMAN
NC score	0.082666 (rank : 15)	θ value	θ > 10 (rank : 22)
Query Neighborhood Hits	21	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	O95352, Q7L8L0, Q9BWP2, Q9UFH4	Gene names	ATG7, APG7L
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 7 (APG7-like) (Ubiquitin-activating enzyme E1-like protein) (hAGP7).

ATG7_MOUSE
NC score	0.082187 (rank : 16)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	21	Target Neighborhood Hits	16	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D906, Q3TCD9, Q8K4Q5	Gene names	Atg7, Apg7l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 7 (APG7-like) (Ubiquitin-activating enzyme E1-like protein) (mAGP7).

GA6S_HUMAN
NC score	0.022560 (rank : 17)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P34059, Q86VK3	Gene names	GALNS
Domain Architecture
Description	N-acetylgalactosamine-6-sulfatase precursor (EC 3.1.6.4) (N- acetylgalactosamine-6-sulfate sulfatase) (Galactose-6-sulfate sulfatase) (GalNAc6S sulfatase) (Chondroitinsulfatase) (Chondroitinase).

PDIA1_MOUSE
NC score	0.011590 (rank : 18)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	P09103	Gene names	P4hb, Pdia1
Domain Architecture
Description	Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) (Prolyl 4- hydroxylase subunit beta) (Cellular thyroid hormone-binding protein) (p55) (Erp59).

CHD9_MOUSE
NC score	0.010676 (rank : 19)	θ value	1.81305 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	427	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

SCEL_MOUSE
NC score	0.010020 (rank : 20)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EQG3, Q9CTT9	Gene names	Scel
Domain Architecture
Description	Sciellin.

CHD9_HUMAN
NC score	0.008239 (rank : 21)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	343	Shared Neighborhood Hits	3
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CLAP2_MOUSE
NC score	0.007911 (rank : 22)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BRT1, Q8CHE3, Q99JI3, Q9DB80	Gene names	Clasp2, Kiaa0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

ZBT7A_HUMAN
NC score	0.004573 (rank : 23)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	823	Shared Neighborhood Hits	3
SwissProt Accessions	O95365, O00456	Gene names	ZBTB7A, FBI1, LRF, ZBTB7
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma- related factor) (Factor that binds to inducer of short transcripts protein 1) (Factor binding IST protein 1) (FBI-1) (HIV-1 1st-binding protein 1) (TTF-I-interacting peptide 21) (TIP21).