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Network neighborhood for query Sequence : MOCS3_HUMAN

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MOCS3_HUMAN
SwissProt Accessions	O95396	Gene names	MOCS3
Domain Architecture
Description	Molybdenum cofactor synthesis protein 3 (Molybdopterin synthase sulfurylase) (MPT synthase sulfurylase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MOCS3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	O95396	Gene names	MOCS3
Domain Architecture
Description	Molybdenum cofactor synthesis protein 3 (Molybdopterin synthase sulfurylase) (MPT synthase sulfurylase).

ULE1B_MOUSE
θ value	2.88119e-14 (rank : 2)	NC score	0.669466 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	56	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z1F9, Q8BVX9	Gene names	Uble1b, Sae2, Uba2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

UBE1_MOUSE
θ value	6.64225e-11 (rank : 3)	NC score	0.609982 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	Q02053, Q542H8	Gene names	Ube1x, Uba1, Ube1
Domain Architecture
Description	Ubiquitin-activating enzyme E1 1.

ULE1B_HUMAN
θ value	1.9326e-10 (rank : 4)	NC score	0.643794 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	31	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UBT2, O95605, Q9NTJ1, Q9UED2	Gene names	UBLE1B, SAE2, UBA2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

UBE1L_HUMAN
θ value	2.52405e-10 (rank : 5)	NC score	0.617097 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	P41226	Gene names	UBE1L, UBE2
Domain Architecture
Description	Ubiquitin-activating enzyme E1 homolog (D8).

UBE1_HUMAN
θ value	9.59137e-10 (rank : 6)	NC score	0.604913 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	P22314, Q96E13	Gene names	UBE1
Domain Architecture
Description	Ubiquitin-activating enzyme E1 (A1S9 protein).

UBA3_MOUSE
θ value	4.0297e-08 (rank : 7)	NC score	0.610921 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C878, O88598, Q9D6B7	Gene names	Ube1c, Uba3
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (Ubiquitin- activating enzyme 3) (NEDD8-activating enzyme E1C) (Ubiquitin- activating enzyme E1C).

UBA3_HUMAN
θ value	5.26297e-08 (rank : 8)	NC score	0.609670 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TBC4, O76088, Q9NTU3	Gene names	UBE1C, UBA3
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (Ubiquitin- activating enzyme 3) (NEDD8-activating enzyme E1C) (Ubiquitin- activating enzyme E1C).

UE1D1_MOUSE
θ value	2.61198e-07 (rank : 9)	NC score	0.503647 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VE47, Q9CYD6	Gene names	Ube1dc1
Domain Architecture	No domain graphic available
Description	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme).

UE1D1_HUMAN
θ value	4.45536e-07 (rank : 10)	NC score	0.502997 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	Q9GZZ9, Q96ST1	Gene names	UBE1DC1, UBA5
Domain Architecture	No domain graphic available
Description	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme) (Ubiquitin-activating enzyme 5) (ThiFP1).

ULE1A_HUMAN
θ value	0.000461057 (rank : 11)	NC score	0.486844 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	18	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UBE0, O95717, Q9P020	Gene names	UBLE1A, AOS1, SAE1, SUA1
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1A (SUMO-1-activating enzyme subunit 1).

ULE1A_MOUSE
θ value	0.000602161 (rank : 12)	NC score	0.482618 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R1T2, Q3TWJ0, Q9CSW9	Gene names	Uble1a, Aos1, Sae1, Sua1, Ubl1a1
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1A (SUMO-1-activating enzyme subunit 1).

ULA1_MOUSE
θ value	0.0193708 (rank : 13)	NC score	0.366413 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VBW6, Q8CFL6	Gene names	Appbp1
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 regulatory subunit (Amyloid protein-binding protein 1) (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1).

ULA1_HUMAN
θ value	0.0563607 (rank : 14)	NC score	0.361107 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	Q13564	Gene names	APPBP1
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 regulatory subunit (Amyloid protein-binding protein 1) (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1) (Protooncogene protein 1) (HPP1).

ATG7_HUMAN
θ value	1.06291 (rank : 15)	NC score	0.145493 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	O95352, Q7L8L0, Q9BWP2, Q9UFH4	Gene names	ATG7, APG7L
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 7 (APG7-like) (Ubiquitin-activating enzyme E1-like protein) (hAGP7).

ATG7_MOUSE
θ value	1.38821 (rank : 16)	NC score	0.144726 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D906, Q3TCD9, Q8K4Q5	Gene names	Atg7, Apg7l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 7 (APG7-like) (Ubiquitin-activating enzyme E1-like protein) (mAGP7).

KAT_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.059900 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NFU3, Q5SY48, Q5SY49, Q5SY50, Q5SY51, Q8NFU2, Q9BV22	Gene names	KAT
Domain Architecture	No domain graphic available
Description	Putative thiosulfate sulfurtransferase KAT (EC 2.8.1.1).

IF4G3_MOUSE
θ value	6.88961 (rank : 18)	NC score	0.013671 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	279	Shared Neighborhood Hits	2
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

ZFYV9_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.014898 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

K1543_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.013919 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	435	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

Hits sorted by NC score

MOCS3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	O95396	Gene names	MOCS3
Domain Architecture
Description	Molybdenum cofactor synthesis protein 3 (Molybdopterin synthase sulfurylase) (MPT synthase sulfurylase).

ULE1B_MOUSE
NC score	0.669466 (rank : 2)	θ value	2.88119e-14 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	56	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z1F9, Q8BVX9	Gene names	Uble1b, Sae2, Uba2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

ULE1B_HUMAN
NC score	0.643794 (rank : 3)	θ value	1.9326e-10 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	31	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UBT2, O95605, Q9NTJ1, Q9UED2	Gene names	UBLE1B, SAE2, UBA2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

UBE1L_HUMAN
NC score	0.617097 (rank : 4)	θ value	2.52405e-10 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	P41226	Gene names	UBE1L, UBE2
Domain Architecture
Description	Ubiquitin-activating enzyme E1 homolog (D8).

UBA3_MOUSE
NC score	0.610921 (rank : 5)	θ value	4.0297e-08 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C878, O88598, Q9D6B7	Gene names	Ube1c, Uba3
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (Ubiquitin- activating enzyme 3) (NEDD8-activating enzyme E1C) (Ubiquitin- activating enzyme E1C).

UBE1_MOUSE
NC score	0.609982 (rank : 6)	θ value	6.64225e-11 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	Q02053, Q542H8	Gene names	Ube1x, Uba1, Ube1
Domain Architecture
Description	Ubiquitin-activating enzyme E1 1.

UBA3_HUMAN
NC score	0.609670 (rank : 7)	θ value	5.26297e-08 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TBC4, O76088, Q9NTU3	Gene names	UBE1C, UBA3
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (Ubiquitin- activating enzyme 3) (NEDD8-activating enzyme E1C) (Ubiquitin- activating enzyme E1C).

UBE1_HUMAN
NC score	0.604913 (rank : 8)	θ value	9.59137e-10 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	P22314, Q96E13	Gene names	UBE1
Domain Architecture
Description	Ubiquitin-activating enzyme E1 (A1S9 protein).

UE1D1_MOUSE
NC score	0.503647 (rank : 9)	θ value	2.61198e-07 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VE47, Q9CYD6	Gene names	Ube1dc1
Domain Architecture	No domain graphic available
Description	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme).

UE1D1_HUMAN
NC score	0.502997 (rank : 10)	θ value	4.45536e-07 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	Q9GZZ9, Q96ST1	Gene names	UBE1DC1, UBA5
Domain Architecture	No domain graphic available
Description	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme) (Ubiquitin-activating enzyme 5) (ThiFP1).

ULE1A_HUMAN
NC score	0.486844 (rank : 11)	θ value	0.000461057 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	18	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UBE0, O95717, Q9P020	Gene names	UBLE1A, AOS1, SAE1, SUA1
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1A (SUMO-1-activating enzyme subunit 1).

ULE1A_MOUSE
NC score	0.482618 (rank : 12)	θ value	0.000602161 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R1T2, Q3TWJ0, Q9CSW9	Gene names	Uble1a, Aos1, Sae1, Sua1, Ubl1a1
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1A (SUMO-1-activating enzyme subunit 1).

ULA1_MOUSE
NC score	0.366413 (rank : 13)	θ value	0.0193708 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VBW6, Q8CFL6	Gene names	Appbp1
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 regulatory subunit (Amyloid protein-binding protein 1) (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1).

ULA1_HUMAN
NC score	0.361107 (rank : 14)	θ value	0.0563607 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	Q13564	Gene names	APPBP1
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 regulatory subunit (Amyloid protein-binding protein 1) (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1) (Protooncogene protein 1) (HPP1).

ATG7_HUMAN
NC score	0.145493 (rank : 15)	θ value	1.06291 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	O95352, Q7L8L0, Q9BWP2, Q9UFH4	Gene names	ATG7, APG7L
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 7 (APG7-like) (Ubiquitin-activating enzyme E1-like protein) (hAGP7).

ATG7_MOUSE
NC score	0.144726 (rank : 16)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D906, Q3TCD9, Q8K4Q5	Gene names	Atg7, Apg7l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 7 (APG7-like) (Ubiquitin-activating enzyme E1-like protein) (mAGP7).

KAT_HUMAN
NC score	0.059900 (rank : 17)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NFU3, Q5SY48, Q5SY49, Q5SY50, Q5SY51, Q8NFU2, Q9BV22	Gene names	KAT
Domain Architecture	No domain graphic available
Description	Putative thiosulfate sulfurtransferase KAT (EC 2.8.1.1).

ZFYV9_HUMAN
NC score	0.014898 (rank : 18)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

K1543_HUMAN
NC score	0.013919 (rank : 19)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	435	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

IF4G3_MOUSE
NC score	0.013671 (rank : 20)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	279	Shared Neighborhood Hits	2
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).