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Network neighborhood for query Sequence : ENPP1_HUMAN

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ENPP1_HUMAN
SwissProt Accessions	P22413, Q5T9R6, Q9NPZ3, Q9P1P6, Q9UP61, Q9Y6K3	Gene names	ENPP1, NPPS, PC1, PDNP1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ENPP1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	P22413, Q5T9R6, Q9NPZ3, Q9P1P6, Q9UP61, Q9Y6K3	Gene names	ENPP1, NPPS, PC1, PDNP1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP1_MOUSE
θ value	0 (rank : 2)	NC score	0.993516 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	65	Shared Neighborhood Hits	26
SwissProt Accessions	P06802	Gene names	Enpp1, Npps, Pc1, Pdnp1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) (Antigen Ly-41) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP2_HUMAN
θ value	0 (rank : 3)	NC score	0.975312 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	61	Shared Neighborhood Hits	26
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP2_MOUSE
θ value	0 (rank : 4)	NC score	0.975756 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	66	Shared Neighborhood Hits	28
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP3_HUMAN
θ value	0 (rank : 5)	NC score	0.989046 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	34	Shared Neighborhood Hits	19
SwissProt Accessions	O14638	Gene names	ENPP3, PDNP3
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 3 (E-NPP 3) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (Phosphodiesterase I beta) (PD-Ibeta) (CD203c antigen) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP5_MOUSE
θ value	1.6097e-65 (rank : 6)	NC score	0.891055 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EQG7, Q921P7	Gene names	Enpp5
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 5 precursor (EC 3.1.-.-) (E-NPP5) (NPP-5).

ENPP5_HUMAN
θ value	1.96772e-63 (rank : 7)	NC score	0.890968 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UJA9, Q6UX49	Gene names	ENPP5
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 5 precursor (EC 3.1.-.-) (E-NPP5) (NPP-5).

ENPP6_HUMAN
θ value	6.56568e-51 (rank : 8)	NC score	0.868958 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	Q6UWR7, Q96M57	Gene names	ENPP6
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 6 precursor (EC 3.1.-.-) (E-NPP6) (NPP-6) [Contains: Ectonucleotide pyrophosphatase/phosphodiesterase 6 soluble form].

ENPP6_MOUSE
θ value	3.04986e-48 (rank : 9)	NC score	0.866532 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BGN3, Q4VAH5	Gene names	Enpp6
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 6 precursor (EC 3.1.-.-) (E-NPP6) (NPP-6) [Contains: Ectonucleotide pyrophosphatase/phosphodiesterase 6 soluble form].

ENPP7_HUMAN
θ value	7.51208e-47 (rank : 10)	NC score	0.886609 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q6UWV6, Q6ZTS5, Q8IUS8	Gene names	ENPP7
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 7 precursor (EC 3.1.4.12) (E-NPP7) (NPP-7) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase).

PRG4_MOUSE
θ value	3.08544e-08 (rank : 11)	NC score	0.198388 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	624	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_HUMAN
θ value	7.59969e-07 (rank : 12)	NC score	0.177194 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	764	Shared Neighborhood Hits	14
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PP11_HUMAN
θ value	9.29e-05 (rank : 13)	NC score	0.311499 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	P21128, Q2NKJ4	Gene names
Domain Architecture
Description	Placental protein 11 precursor (EC 3.4.21.-) (PP11).

VTNC_MOUSE
θ value	0.00390308 (rank : 14)	NC score	0.154892 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	74	Shared Neighborhood Hits	12
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

SUSD2_HUMAN
θ value	0.0193708 (rank : 15)	NC score	0.109766 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	99	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

TINAG_HUMAN
θ value	0.0330416 (rank : 16)	NC score	0.087795 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	63	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UJW2, Q9UJW1, Q9ULZ4	Gene names	TINAG
Domain Architecture
Description	Tubulointerstitial nephritis antigen (TIN-Ag).

VTNC_HUMAN
θ value	0.0330416 (rank : 17)	NC score	0.146440 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	66	Shared Neighborhood Hits	12
SwissProt Accessions	P04004, P01141, Q9BSH7	Gene names	VTN
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein) (V75) [Contains: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin B].

NUCGL_HUMAN
θ value	0.0563607 (rank : 18)	NC score	0.067604 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2C4	Gene names	ENDOGL1, ENGL
Domain Architecture
Description	Endonuclease G-like 1 (EC 3.1.30.-) (Endo G-like).

EXTL3_HUMAN
θ value	0.279714 (rank : 19)	NC score	0.022289 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	113	Shared Neighborhood Hits	2
SwissProt Accessions	O43909, O00225	Gene names	EXTL3, EXTL1L, EXTR1, KIAA0519
Domain Architecture
Description	Exostosin-like 3 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXTL3) (Multiple exostosis-like protein 3) (Hereditary multiple exostoses gene isolog) (EXT-related protein 1).

SUSD2_MOUSE
θ value	0.279714 (rank : 20)	NC score	0.092404 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	104	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

PIGO_HUMAN
θ value	0.365318 (rank : 21)	NC score	0.138932 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	24	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TEQ8, Q6P154, Q6UX80, Q8TDS8, Q96CS9, Q9BVN9, Q9Y4B0	Gene names	PIGO
Domain Architecture
Description	GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O).

SLIK5_HUMAN
θ value	0.365318 (rank : 22)	NC score	0.012871 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	302	Shared Neighborhood Hits	3
SwissProt Accessions	O94991	Gene names	SLITRK5, KIAA0918, LRRC11
Domain Architecture
Description	SLIT and NTRK-like protein 5 precursor (Leucine-rich repeat-containing protein 11).

LRP1B_HUMAN
θ value	0.47712 (rank : 23)	NC score	0.033412 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	602	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP2_HUMAN
θ value	0.62314 (rank : 24)	NC score	0.032781 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	573	Shared Neighborhood Hits	23
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

SORL_HUMAN
θ value	0.62314 (rank : 25)	NC score	0.030090 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	440	Shared Neighborhood Hits	19
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
θ value	0.62314 (rank : 26)	NC score	0.029697 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	439	Shared Neighborhood Hits	19
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

TENA_MOUSE
θ value	0.813845 (rank : 27)	NC score	0.025848 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	596	Shared Neighborhood Hits	20
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

SLIK5_MOUSE
θ value	1.06291 (rank : 28)	NC score	0.011671 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	301	Shared Neighborhood Hits	3
SwissProt Accessions	Q810B7, Q9CT21	Gene names	Slitrk5
Domain Architecture
Description	SLIT and NTRK-like protein 5 precursor.

TENA_HUMAN
θ value	1.06291 (rank : 29)	NC score	0.025820 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	631	Shared Neighborhood Hits	22
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENR_HUMAN
θ value	1.06291 (rank : 30)	NC score	0.027383 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	526	Shared Neighborhood Hits	19
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

PIGO_MOUSE
θ value	1.38821 (rank : 31)	NC score	0.132008 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JJI6, Q9CRY2	Gene names	Pigo
Domain Architecture
Description	GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O).

CRUM1_HUMAN
θ value	1.81305 (rank : 32)	NC score	0.016813 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	457	Shared Neighborhood Hits	18
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	1.81305 (rank : 33)	NC score	0.016409 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	444	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

E2AK3_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.002157 (rank : 49)
Query Neighborhood Hits	47	Target Neighborhood Hits	859	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZJ5, O95846	Gene names	EIF2AK3, PEK, PERK
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 3 precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK).

LPHN1_HUMAN
θ value	1.81305 (rank : 35)	NC score	0.006252 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	155	Shared Neighborhood Hits	2
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

TENR_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.025685 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	531	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

FBN1_HUMAN
θ value	3.0926 (rank : 37)	NC score	0.017603 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	557	Shared Neighborhood Hits	21
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBLN1_MOUSE
θ value	4.03905 (rank : 38)	NC score	0.014033 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	329	Shared Neighborhood Hits	16
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBN1_MOUSE
θ value	4.03905 (rank : 39)	NC score	0.016433 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	563	Shared Neighborhood Hits	20
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

LRP4_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.026541 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	355	Shared Neighborhood Hits	20
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.026821 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	351	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

CP4F3_HUMAN
θ value	5.27518 (rank : 42)	NC score	0.002819 (rank : 48)
Query Neighborhood Hits	47	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q08477, O60634, Q5U740	Gene names	CYP4F3, LTB4H
Domain Architecture
Description	Cytochrome P450 4F3 (EC 1.14.13.30) (CYPIVF3) (Leukotriene-B(4) omega- hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB- omega).

LRP1B_MOUSE
θ value	5.27518 (rank : 43)	NC score	0.029226 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	606	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

ATRN_HUMAN
θ value	6.88961 (rank : 44)	NC score	0.010017 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	525	Shared Neighborhood Hits	17
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

FAK2_HUMAN
θ value	6.88961 (rank : 45)	NC score	-0.000300 (rank : 50)
Query Neighborhood Hits	47	Target Neighborhood Hits	847	Shared Neighborhood Hits	5
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FAK2_MOUSE
θ value	6.88961 (rank : 46)	NC score	-0.000495 (rank : 51)
Query Neighborhood Hits	47	Target Neighborhood Hits	851	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

GRN_HUMAN
θ value	6.88961 (rank : 47)	NC score	0.024797 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	268	Shared Neighborhood Hits	17
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

KRA59_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.055434 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	310	Shared Neighborhood Hits	19
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

PIGG_HUMAN
θ value	θ > 10 (rank : 49)	NC score	0.126907 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	27	Shared Neighborhood Hits	9
SwissProt Accessions	Q5H8A4, Q2TAK5, Q6UX31, Q7L5Y4, Q8N866, Q8NCC9, Q96SY9, Q9BVT7, Q9NXG5	Gene names	PIGG, GPI7
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class G protein) (PIG-G) (GPI7 homolog) (hGPI7).

PIGN_HUMAN
θ value	θ > 10 (rank : 50)	NC score	0.053391 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	O95427, Q7L8F8, Q8TC01, Q9NT05	Gene names	PIGN, MCD4
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N) (MCD4 homolog).

PIGN_MOUSE
θ value	θ > 10 (rank : 51)	NC score	0.061919 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	29	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R1S3, Q3V0S6, Q8VCC3, Q9R1S1, Q9R1S2	Gene names	Pign
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N).

Hits sorted by NC score

ENPP1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	P22413, Q5T9R6, Q9NPZ3, Q9P1P6, Q9UP61, Q9Y6K3	Gene names	ENPP1, NPPS, PC1, PDNP1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP1_MOUSE
NC score	0.993516 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	65	Shared Neighborhood Hits	26
SwissProt Accessions	P06802	Gene names	Enpp1, Npps, Pc1, Pdnp1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) (Antigen Ly-41) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP3_HUMAN
NC score	0.989046 (rank : 3)	θ value	0 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	34	Shared Neighborhood Hits	19
SwissProt Accessions	O14638	Gene names	ENPP3, PDNP3
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 3 (E-NPP 3) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (Phosphodiesterase I beta) (PD-Ibeta) (CD203c antigen) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP2_MOUSE
NC score	0.975756 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	66	Shared Neighborhood Hits	28
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP2_HUMAN
NC score	0.975312 (rank : 5)	θ value	0 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	61	Shared Neighborhood Hits	26
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP5_MOUSE
NC score	0.891055 (rank : 6)	θ value	1.6097e-65 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EQG7, Q921P7	Gene names	Enpp5
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 5 precursor (EC 3.1.-.-) (E-NPP5) (NPP-5).

ENPP5_HUMAN
NC score	0.890968 (rank : 7)	θ value	1.96772e-63 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UJA9, Q6UX49	Gene names	ENPP5
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 5 precursor (EC 3.1.-.-) (E-NPP5) (NPP-5).

ENPP7_HUMAN
NC score	0.886609 (rank : 8)	θ value	7.51208e-47 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q6UWV6, Q6ZTS5, Q8IUS8	Gene names	ENPP7
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 7 precursor (EC 3.1.4.12) (E-NPP7) (NPP-7) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase).

ENPP6_HUMAN
NC score	0.868958 (rank : 9)	θ value	6.56568e-51 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	Q6UWR7, Q96M57	Gene names	ENPP6
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 6 precursor (EC 3.1.-.-) (E-NPP6) (NPP-6) [Contains: Ectonucleotide pyrophosphatase/phosphodiesterase 6 soluble form].

ENPP6_MOUSE
NC score	0.866532 (rank : 10)	θ value	3.04986e-48 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BGN3, Q4VAH5	Gene names	Enpp6
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 6 precursor (EC 3.1.-.-) (E-NPP6) (NPP-6) [Contains: Ectonucleotide pyrophosphatase/phosphodiesterase 6 soluble form].

PP11_HUMAN
NC score	0.311499 (rank : 11)	θ value	9.29e-05 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	P21128, Q2NKJ4	Gene names
Domain Architecture
Description	Placental protein 11 precursor (EC 3.4.21.-) (PP11).

PRG4_MOUSE
NC score	0.198388 (rank : 12)	θ value	3.08544e-08 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	624	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_HUMAN
NC score	0.177194 (rank : 13)	θ value	7.59969e-07 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	764	Shared Neighborhood Hits	14
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

VTNC_MOUSE
NC score	0.154892 (rank : 14)	θ value	0.00390308 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	74	Shared Neighborhood Hits	12
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

VTNC_HUMAN
NC score	0.146440 (rank : 15)	θ value	0.0330416 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	66	Shared Neighborhood Hits	12
SwissProt Accessions	P04004, P01141, Q9BSH7	Gene names	VTN
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein) (V75) [Contains: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin B].

PIGO_HUMAN
NC score	0.138932 (rank : 16)	θ value	0.365318 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	24	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TEQ8, Q6P154, Q6UX80, Q8TDS8, Q96CS9, Q9BVN9, Q9Y4B0	Gene names	PIGO
Domain Architecture
Description	GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O).

PIGO_MOUSE
NC score	0.132008 (rank : 17)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JJI6, Q9CRY2	Gene names	Pigo
Domain Architecture
Description	GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O).

PIGG_HUMAN
NC score	0.126907 (rank : 18)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	47	Target Neighborhood Hits	27	Shared Neighborhood Hits	9
SwissProt Accessions	Q5H8A4, Q2TAK5, Q6UX31, Q7L5Y4, Q8N866, Q8NCC9, Q96SY9, Q9BVT7, Q9NXG5	Gene names	PIGG, GPI7
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class G protein) (PIG-G) (GPI7 homolog) (hGPI7).

SUSD2_HUMAN
NC score	0.109766 (rank : 19)	θ value	0.0193708 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	99	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

SUSD2_MOUSE
NC score	0.092404 (rank : 20)	θ value	0.279714 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	104	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

TINAG_HUMAN
NC score	0.087795 (rank : 21)	θ value	0.0330416 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	63	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UJW2, Q9UJW1, Q9ULZ4	Gene names	TINAG
Domain Architecture
Description	Tubulointerstitial nephritis antigen (TIN-Ag).

NUCGL_HUMAN
NC score	0.067604 (rank : 22)	θ value	0.0563607 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2C4	Gene names	ENDOGL1, ENGL
Domain Architecture
Description	Endonuclease G-like 1 (EC 3.1.30.-) (Endo G-like).

PIGN_MOUSE
NC score	0.061919 (rank : 23)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	47	Target Neighborhood Hits	29	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R1S3, Q3V0S6, Q8VCC3, Q9R1S1, Q9R1S2	Gene names	Pign
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N).

KRA59_HUMAN
NC score	0.055434 (rank : 24)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	47	Target Neighborhood Hits	310	Shared Neighborhood Hits	19
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

PIGN_HUMAN
NC score	0.053391 (rank : 25)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	47	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	O95427, Q7L8F8, Q8TC01, Q9NT05	Gene names	PIGN, MCD4
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N) (MCD4 homolog).

LRP1B_HUMAN
NC score	0.033412 (rank : 26)	θ value	0.47712 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	602	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP2_HUMAN
NC score	0.032781 (rank : 27)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	573	Shared Neighborhood Hits	23
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

SORL_HUMAN
NC score	0.030090 (rank : 28)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	440	Shared Neighborhood Hits	19
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
NC score	0.029697 (rank : 29)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	439	Shared Neighborhood Hits	19
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

LRP1B_MOUSE
NC score	0.029226 (rank : 30)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	606	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

TENR_HUMAN
NC score	0.027383 (rank : 31)	θ value	1.06291 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	526	Shared Neighborhood Hits	19
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

LRP4_MOUSE
NC score	0.026821 (rank : 32)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	351	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP4_HUMAN
NC score	0.026541 (rank : 33)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	355	Shared Neighborhood Hits	20
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

TENA_MOUSE
NC score	0.025848 (rank : 34)	θ value	0.813845 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	596	Shared Neighborhood Hits	20
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENA_HUMAN
NC score	0.025820 (rank : 35)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	631	Shared Neighborhood Hits	22
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENR_MOUSE
NC score	0.025685 (rank : 36)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	531	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

GRN_HUMAN
NC score	0.024797 (rank : 37)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	268	Shared Neighborhood Hits	17
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

EXTL3_HUMAN
NC score	0.022289 (rank : 38)	θ value	0.279714 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	113	Shared Neighborhood Hits	2
SwissProt Accessions	O43909, O00225	Gene names	EXTL3, EXTL1L, EXTR1, KIAA0519
Domain Architecture
Description	Exostosin-like 3 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXTL3) (Multiple exostosis-like protein 3) (Hereditary multiple exostoses gene isolog) (EXT-related protein 1).

FBN1_HUMAN
NC score	0.017603 (rank : 39)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	557	Shared Neighborhood Hits	21
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

CRUM1_HUMAN
NC score	0.016813 (rank : 40)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	457	Shared Neighborhood Hits	18
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

FBN1_MOUSE
NC score	0.016433 (rank : 41)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	563	Shared Neighborhood Hits	20
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

CRUM1_MOUSE
NC score	0.016409 (rank : 42)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	444	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

FBLN1_MOUSE
NC score	0.014033 (rank : 43)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	329	Shared Neighborhood Hits	16
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

SLIK5_HUMAN
NC score	0.012871 (rank : 44)	θ value	0.365318 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	302	Shared Neighborhood Hits	3
SwissProt Accessions	O94991	Gene names	SLITRK5, KIAA0918, LRRC11
Domain Architecture
Description	SLIT and NTRK-like protein 5 precursor (Leucine-rich repeat-containing protein 11).

SLIK5_MOUSE
NC score	0.011671 (rank : 45)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	301	Shared Neighborhood Hits	3
SwissProt Accessions	Q810B7, Q9CT21	Gene names	Slitrk5
Domain Architecture
Description	SLIT and NTRK-like protein 5 precursor.

ATRN_HUMAN
NC score	0.010017 (rank : 46)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	525	Shared Neighborhood Hits	17
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

LPHN1_HUMAN
NC score	0.006252 (rank : 47)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	155	Shared Neighborhood Hits	2
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

CP4F3_HUMAN
NC score	0.002819 (rank : 48)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q08477, O60634, Q5U740	Gene names	CYP4F3, LTB4H
Domain Architecture
Description	Cytochrome P450 4F3 (EC 1.14.13.30) (CYPIVF3) (Leukotriene-B(4) omega- hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB- omega).

E2AK3_HUMAN
NC score	0.002157 (rank : 49)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	859	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZJ5, O95846	Gene names	EIF2AK3, PEK, PERK
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 3 precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK).

FAK2_HUMAN
NC score	-0.000300 (rank : 50)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	847	Shared Neighborhood Hits	5
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FAK2_MOUSE
NC score	-0.000495 (rank : 51)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	851	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).