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Network neighborhood for query Sequence : PP11_HUMAN

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PP11_HUMAN
SwissProt Accessions	P21128, Q2NKJ4	Gene names
Domain Architecture
Description	Placental protein 11 precursor (EC 3.4.21.-) (PP11).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PP11_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	P21128, Q2NKJ4	Gene names
Domain Architecture
Description	Placental protein 11 precursor (EC 3.4.21.-) (PP11).

PRG4_HUMAN
θ value	8.11959e-09 (rank : 2)	NC score	0.256344 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	764	Shared Neighborhood Hits	12
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_MOUSE
θ value	1.80886e-08 (rank : 3)	NC score	0.270850 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	624	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

ENPP1_HUMAN
θ value	9.29e-05 (rank : 4)	NC score	0.311499 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	P22413, Q5T9R6, Q9NPZ3, Q9P1P6, Q9UP61, Q9Y6K3	Gene names	ENPP1, NPPS, PC1, PDNP1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP1_MOUSE
θ value	0.000270298 (rank : 5)	NC score	0.310137 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	65	Shared Neighborhood Hits	12
SwissProt Accessions	P06802	Gene names	Enpp1, Npps, Pc1, Pdnp1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) (Antigen Ly-41) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

VTNC_HUMAN
θ value	0.000270298 (rank : 6)	NC score	0.275127 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	66	Shared Neighborhood Hits	12
SwissProt Accessions	P04004, P01141, Q9BSH7	Gene names	VTN
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein) (V75) [Contains: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin B].

ENPP2_MOUSE
θ value	0.00298849 (rank : 7)	NC score	0.300217 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	66	Shared Neighborhood Hits	12
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP2_HUMAN
θ value	0.00390308 (rank : 8)	NC score	0.300294 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	61	Shared Neighborhood Hits	12
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP3_HUMAN
θ value	0.00509761 (rank : 9)	NC score	0.291222 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	O14638	Gene names	ENPP3, PDNP3
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 3 (E-NPP 3) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (Phosphodiesterase I beta) (PD-Ibeta) (CD203c antigen) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

VTNC_MOUSE
θ value	0.0113563 (rank : 10)	NC score	0.253478 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	74	Shared Neighborhood Hits	11
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

K6PP_MOUSE
θ value	0.365318 (rank : 11)	NC score	0.054775 (rank : 24)
Query Neighborhood Hits	20	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WUA3, Q3TNA9, Q3U4P1, Q3U7G4, Q4KUG1, Q543K8, Q8C5I6, Q9JI86	Gene names	Pfkp, Pfkc
Domain Architecture
Description	6-phosphofructokinase type C (EC 2.7.1.11) (Phosphofructokinase 1) (Phosphohexokinase) (Phosphofructo-1-kinase isozyme C) (PFK-C).

SUSD2_HUMAN
θ value	1.38821 (rank : 12)	NC score	0.093780 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	99	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

SYNE2_HUMAN
θ value	1.38821 (rank : 13)	NC score	0.017885 (rank : 30)
Query Neighborhood Hits	20	Target Neighborhood Hits	1323	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

K6PP_HUMAN
θ value	4.03905 (rank : 14)	NC score	0.043786 (rank : 28)
Query Neighborhood Hits	20	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q01813	Gene names	PFKP, PFKF
Domain Architecture
Description	6-phosphofructokinase type C (EC 2.7.1.11) (Phosphofructokinase 1) (Phosphohexokinase) (Phosphofructo-1-kinase isozyme C) (PFK-C) (6- phosphofructokinase, platelet type).

SCNNG_MOUSE
θ value	5.27518 (rank : 15)	NC score	0.017862 (rank : 31)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WU39	Gene names	Scnn1g
Domain Architecture
Description	Amiloride-sensitive sodium channel gamma-subunit (Epithelial Na+ channel subunit gamma) (Gamma ENaC) (Nonvoltage-gated sodium channel 1 subunit gamma) (SCNEG) (Gamma NaCH).

SUSD2_MOUSE
θ value	5.27518 (rank : 16)	NC score	0.079154 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	104	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

RBP2_MOUSE
θ value	8.99809 (rank : 17)	NC score	0.008967 (rank : 33)
Query Neighborhood Hits	20	Target Neighborhood Hits	232	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

RED2_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.013731 (rank : 32)
Query Neighborhood Hits	20	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NS39	Gene names	ADARB2, ADAR3, RED2
Domain Architecture
Description	Double-stranded RNA-specific editase B2 (EC 3.5.-.-) (dsRNA adenosine deaminase B2) (RNA-dependent adenosine deaminase 3) (RNA-editing deaminase 2) (RNA-editing enzyme 2).

TMEM5_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.021809 (rank : 29)
Query Neighborhood Hits	20	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VDX6, Q8R566	Gene names	Tmem5
Domain Architecture	No domain graphic available
Description	Transmembrane protein 5.

ZNF74_HUMAN
θ value	8.99809 (rank : 20)	NC score	-0.000163 (rank : 34)
Query Neighborhood Hits	20	Target Neighborhood Hits	770	Shared Neighborhood Hits	2
SwissProt Accessions	Q16587, Q6IBV2, Q9UC04, Q9UF05, Q9UF06, Q9UF07	Gene names	ZNF74
Domain Architecture
Description	Zinc finger protein 74 (hZNF7).

ENPP5_HUMAN
θ value	θ > 10 (rank : 21)	NC score	0.154334 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UJA9, Q6UX49	Gene names	ENPP5
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 5 precursor (EC 3.1.-.-) (E-NPP5) (NPP-5).

ENPP5_MOUSE
θ value	θ > 10 (rank : 22)	NC score	0.154069 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EQG7, Q921P7	Gene names	Enpp5
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 5 precursor (EC 3.1.-.-) (E-NPP5) (NPP-5).

ENPP6_HUMAN
θ value	θ > 10 (rank : 23)	NC score	0.148833 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q6UWR7, Q96M57	Gene names	ENPP6
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 6 precursor (EC 3.1.-.-) (E-NPP6) (NPP-6) [Contains: Ectonucleotide pyrophosphatase/phosphodiesterase 6 soluble form].

ENPP6_MOUSE
θ value	θ > 10 (rank : 24)	NC score	0.147893 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BGN3, Q4VAH5	Gene names	Enpp6
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 6 precursor (EC 3.1.-.-) (E-NPP6) (NPP-6) [Contains: Ectonucleotide pyrophosphatase/phosphodiesterase 6 soluble form].

ENPP7_HUMAN
θ value	θ > 10 (rank : 25)	NC score	0.156721 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q6UWV6, Q6ZTS5, Q8IUS8	Gene names	ENPP7
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 7 precursor (EC 3.1.4.12) (E-NPP7) (NPP-7) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase).

HEMO_HUMAN
θ value	θ > 10 (rank : 26)	NC score	0.066226 (rank : 22)
Query Neighborhood Hits	20	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	P02790	Gene names	HPX
Domain Architecture
Description	Hemopexin precursor (Beta-1B-glycoprotein).

MDC1_HUMAN
θ value	θ > 10 (rank : 27)	NC score	0.053531 (rank : 26)
Query Neighborhood Hits	20	Target Neighborhood Hits	1446	Shared Neighborhood Hits	3
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PRAX_HUMAN
θ value	θ > 10 (rank : 28)	NC score	0.067966 (rank : 21)
Query Neighborhood Hits	20	Target Neighborhood Hits	215	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PRAX_MOUSE
θ value	θ > 10 (rank : 29)	NC score	0.054766 (rank : 25)
Query Neighborhood Hits	20	Target Neighborhood Hits	199	Shared Neighborhood Hits	2
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

SPR1A_HUMAN
θ value	θ > 10 (rank : 30)	NC score	0.050333 (rank : 27)
Query Neighborhood Hits	20	Target Neighborhood Hits	136	Shared Neighborhood Hits	2
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

SPR1A_MOUSE
θ value	θ > 10 (rank : 31)	NC score	0.065540 (rank : 23)
Query Neighborhood Hits	20	Target Neighborhood Hits	343	Shared Neighborhood Hits	2
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

SPR1B_MOUSE
θ value	θ > 10 (rank : 32)	NC score	0.071263 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	395	Shared Neighborhood Hits	2
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

SPRR3_HUMAN
θ value	θ > 10 (rank : 33)	NC score	0.088858 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

SPRR3_MOUSE
θ value	θ > 10 (rank : 34)	NC score	0.074022 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

Hits sorted by NC score

PP11_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	P21128, Q2NKJ4	Gene names
Domain Architecture
Description	Placental protein 11 precursor (EC 3.4.21.-) (PP11).

ENPP1_HUMAN
NC score	0.311499 (rank : 2)	θ value	9.29e-05 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	P22413, Q5T9R6, Q9NPZ3, Q9P1P6, Q9UP61, Q9Y6K3	Gene names	ENPP1, NPPS, PC1, PDNP1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP1_MOUSE
NC score	0.310137 (rank : 3)	θ value	0.000270298 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	65	Shared Neighborhood Hits	12
SwissProt Accessions	P06802	Gene names	Enpp1, Npps, Pc1, Pdnp1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) (Antigen Ly-41) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP2_HUMAN
NC score	0.300294 (rank : 4)	θ value	0.00390308 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	61	Shared Neighborhood Hits	12
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP2_MOUSE
NC score	0.300217 (rank : 5)	θ value	0.00298849 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	66	Shared Neighborhood Hits	12
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP3_HUMAN
NC score	0.291222 (rank : 6)	θ value	0.00509761 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	O14638	Gene names	ENPP3, PDNP3
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 3 (E-NPP 3) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (Phosphodiesterase I beta) (PD-Ibeta) (CD203c antigen) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

VTNC_HUMAN
NC score	0.275127 (rank : 7)	θ value	0.000270298 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	66	Shared Neighborhood Hits	12
SwissProt Accessions	P04004, P01141, Q9BSH7	Gene names	VTN
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein) (V75) [Contains: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin B].

PRG4_MOUSE
NC score	0.270850 (rank : 8)	θ value	1.80886e-08 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	624	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_HUMAN
NC score	0.256344 (rank : 9)	θ value	8.11959e-09 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	764	Shared Neighborhood Hits	12
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

VTNC_MOUSE
NC score	0.253478 (rank : 10)	θ value	0.0113563 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	74	Shared Neighborhood Hits	11
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

ENPP7_HUMAN
NC score	0.156721 (rank : 11)	θ value	θ > 10 (rank : 25)
Query Neighborhood Hits	20	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q6UWV6, Q6ZTS5, Q8IUS8	Gene names	ENPP7
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 7 precursor (EC 3.1.4.12) (E-NPP7) (NPP-7) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase).

ENPP5_HUMAN
NC score	0.154334 (rank : 12)	θ value	θ > 10 (rank : 21)
Query Neighborhood Hits	20	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UJA9, Q6UX49	Gene names	ENPP5
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 5 precursor (EC 3.1.-.-) (E-NPP5) (NPP-5).

ENPP5_MOUSE
NC score	0.154069 (rank : 13)	θ value	θ > 10 (rank : 22)
Query Neighborhood Hits	20	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EQG7, Q921P7	Gene names	Enpp5
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 5 precursor (EC 3.1.-.-) (E-NPP5) (NPP-5).

ENPP6_HUMAN
NC score	0.148833 (rank : 14)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	20	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q6UWR7, Q96M57	Gene names	ENPP6
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 6 precursor (EC 3.1.-.-) (E-NPP6) (NPP-6) [Contains: Ectonucleotide pyrophosphatase/phosphodiesterase 6 soluble form].

ENPP6_MOUSE
NC score	0.147893 (rank : 15)	θ value	θ > 10 (rank : 24)
Query Neighborhood Hits	20	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BGN3, Q4VAH5	Gene names	Enpp6
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 6 precursor (EC 3.1.-.-) (E-NPP6) (NPP-6) [Contains: Ectonucleotide pyrophosphatase/phosphodiesterase 6 soluble form].

SUSD2_HUMAN
NC score	0.093780 (rank : 16)	θ value	1.38821 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	99	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

SPRR3_HUMAN
NC score	0.088858 (rank : 17)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	20	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

SUSD2_MOUSE
NC score	0.079154 (rank : 18)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	104	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

SPRR3_MOUSE
NC score	0.074022 (rank : 19)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	20	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

SPR1B_MOUSE
NC score	0.071263 (rank : 20)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	20	Target Neighborhood Hits	395	Shared Neighborhood Hits	2
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

PRAX_HUMAN
NC score	0.067966 (rank : 21)	θ value	θ > 10 (rank : 28)
Query Neighborhood Hits	20	Target Neighborhood Hits	215	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

HEMO_HUMAN
NC score	0.066226 (rank : 22)	θ value	θ > 10 (rank : 26)
Query Neighborhood Hits	20	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	P02790	Gene names	HPX
Domain Architecture
Description	Hemopexin precursor (Beta-1B-glycoprotein).

SPR1A_MOUSE
NC score	0.065540 (rank : 23)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	20	Target Neighborhood Hits	343	Shared Neighborhood Hits	2
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

K6PP_MOUSE
NC score	0.054775 (rank : 24)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WUA3, Q3TNA9, Q3U4P1, Q3U7G4, Q4KUG1, Q543K8, Q8C5I6, Q9JI86	Gene names	Pfkp, Pfkc
Domain Architecture
Description	6-phosphofructokinase type C (EC 2.7.1.11) (Phosphofructokinase 1) (Phosphohexokinase) (Phosphofructo-1-kinase isozyme C) (PFK-C).

PRAX_MOUSE
NC score	0.054766 (rank : 25)	θ value	θ > 10 (rank : 29)
Query Neighborhood Hits	20	Target Neighborhood Hits	199	Shared Neighborhood Hits	2
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

MDC1_HUMAN
NC score	0.053531 (rank : 26)	θ value	θ > 10 (rank : 27)
Query Neighborhood Hits	20	Target Neighborhood Hits	1446	Shared Neighborhood Hits	3
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

SPR1A_HUMAN
NC score	0.050333 (rank : 27)	θ value	θ > 10 (rank : 30)
Query Neighborhood Hits	20	Target Neighborhood Hits	136	Shared Neighborhood Hits	2
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

K6PP_HUMAN
NC score	0.043786 (rank : 28)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q01813	Gene names	PFKP, PFKF
Domain Architecture
Description	6-phosphofructokinase type C (EC 2.7.1.11) (Phosphofructokinase 1) (Phosphohexokinase) (Phosphofructo-1-kinase isozyme C) (PFK-C) (6- phosphofructokinase, platelet type).

TMEM5_MOUSE
NC score	0.021809 (rank : 29)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VDX6, Q8R566	Gene names	Tmem5
Domain Architecture	No domain graphic available
Description	Transmembrane protein 5.

SYNE2_HUMAN
NC score	0.017885 (rank : 30)	θ value	1.38821 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	1323	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

SCNNG_MOUSE
NC score	0.017862 (rank : 31)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WU39	Gene names	Scnn1g
Domain Architecture
Description	Amiloride-sensitive sodium channel gamma-subunit (Epithelial Na+ channel subunit gamma) (Gamma ENaC) (Nonvoltage-gated sodium channel 1 subunit gamma) (SCNEG) (Gamma NaCH).

RED2_HUMAN
NC score	0.013731 (rank : 32)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NS39	Gene names	ADARB2, ADAR3, RED2
Domain Architecture
Description	Double-stranded RNA-specific editase B2 (EC 3.5.-.-) (dsRNA adenosine deaminase B2) (RNA-dependent adenosine deaminase 3) (RNA-editing deaminase 2) (RNA-editing enzyme 2).

RBP2_MOUSE
NC score	0.008967 (rank : 33)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	232	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

ZNF74_HUMAN
NC score	-0.000163 (rank : 34)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	770	Shared Neighborhood Hits	2
SwissProt Accessions	Q16587, Q6IBV2, Q9UC04, Q9UF05, Q9UF06, Q9UF07	Gene names	ZNF74
Domain Architecture
Description	Zinc finger protein 74 (hZNF7).