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Network neighborhood for query Sequence : IDE_MOUSE

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IDE_MOUSE
SwissProt Accessions	Q9JHR7	Gene names	Ide
Domain Architecture
Description	Insulin-degrading enzyme (EC 3.4.24.56) (Insulysin) (Insulinase) (Insulin protease).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IDE_HUMAN
θ value	0 (rank : 1)	NC score	0.998956 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	23	Shared Neighborhood Hits	17
SwissProt Accessions	P14735	Gene names	IDE
Domain Architecture
Description	Insulin-degrading enzyme (EC 3.4.24.56) (Insulysin) (Insulinase) (Insulin protease).

IDE_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JHR7	Gene names	Ide
Domain Architecture
Description	Insulin-degrading enzyme (EC 3.4.24.56) (Insulysin) (Insulinase) (Insulin protease).

NRDC_MOUSE
θ value	2.26584e-152 (rank : 3)	NC score	0.911024 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	96	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BHG1	Gene names	Nrd1
Domain Architecture
Description	Nardilysin precursor (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C).

NRDC_HUMAN
θ value	5.22361e-149 (rank : 4)	NC score	0.920621 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	60	Shared Neighborhood Hits	12
SwissProt Accessions	O43847, O15241, O15242, Q5VUL0, Q96HB2, Q9NU57	Gene names	NRD1
Domain Architecture
Description	Nardilysin precursor (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C).

UQCR1_HUMAN
θ value	0.000121331 (rank : 5)	NC score	0.253612 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	P31930, Q96DD2	Gene names	UQCRC1
Domain Architecture
Description	Ubiquinol-cytochrome-c reductase complex core protein I, mitochondrial precursor (EC 1.10.2.2).

MPPB_HUMAN
θ value	0.000158464 (rank : 6)	NC score	0.253508 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	O75439, O60416, Q96FV4	Gene names	PMPCB, MPPB
Domain Architecture
Description	Mitochondrial-processing peptidase subunit beta, mitochondrial precursor (EC 3.4.24.64) (Beta-MPP) (P-52).

MPPA_MOUSE
θ value	0.000602161 (rank : 7)	NC score	0.262144 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DC61, Q3TF19	Gene names	Pmpca, Inpp5e
Domain Architecture
Description	Mitochondrial-processing peptidase alpha subunit, mitochondrial precursor (EC 3.4.24.64) (Alpha-MPP) (P-55).

MPPA_HUMAN
θ value	0.00228821 (rank : 8)	NC score	0.234860 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q10713, Q16639, Q8N513	Gene names	PMPCA, KIAA0123, MPPA
Domain Architecture
Description	Mitochondrial-processing peptidase alpha subunit, mitochondrial precursor (EC 3.4.24.64) (Alpha-MPP) (P-55).

MPPB_MOUSE
θ value	0.00228821 (rank : 9)	NC score	0.234758 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CXT8	Gene names	Pmpcb
Domain Architecture
Description	Mitochondrial-processing peptidase subunit beta, mitochondrial precursor (EC 3.4.24.64) (Beta-MPP) (P-52).

UQCR1_MOUSE
θ value	0.0193708 (rank : 10)	NC score	0.230003 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CZ13, Q9CWL6	Gene names	Uqcrc1
Domain Architecture
Description	Ubiquinol-cytochrome-c reductase complex core protein I, mitochondrial precursor (EC 1.10.2.2).

PREP_HUMAN
θ value	0.0431538 (rank : 11)	NC score	0.135856 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q5JRX3, O95204, Q2M2G6, Q4VBR1, Q5JRW7, Q7L5Z7, Q9BSI6, Q9BVJ5, Q9UPP8	Gene names	PITRM1, KIAA1104, MP1
Domain Architecture	No domain graphic available
Description	Presequence protease, mitochondrial precursor (EC 3.4.24.-) (hPreP) (Pitrilysin metalloproteinase 1) (Metalloprotease 1) (hMP1).

PREP_MOUSE
θ value	0.279714 (rank : 12)	NC score	0.123844 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K411, Q3THC4, Q3TJI1, Q3TPP0, Q3URQ8, Q4KUG2, Q4KUG3, Q6ZPX6, Q922N1, Q9CV63	Gene names	Pitrm1, Kiaa1104, Ntup1
Domain Architecture	No domain graphic available
Description	Presequence protease, mitochondrial precursor (EC 3.4.24.-) (Pitrilysin metalloproteinase 1).

PCDGA_HUMAN
θ value	3.0926 (rank : 13)	NC score	0.005813 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	160	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5H3, Q9Y5E0	Gene names	PCDHGA10
Domain Architecture
Description	Protocadherin gamma A10 precursor (PCDH-gamma-A10).

4EBP1_MOUSE
θ value	4.03905 (rank : 14)	NC score	0.019639 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q60876, Q3TDS8, Q9CZ40	Gene names	Eif4ebp1
Domain Architecture
Description	Eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1) (eIF4E-binding protein 1) (Phosphorylated heat- and acid-stable protein regulated by insulin 1) (PHAS-I).

MUCDL_MOUSE
θ value	4.03905 (rank : 15)	NC score	0.011704 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	461	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

TTC16_HUMAN
θ value	4.03905 (rank : 16)	NC score	0.018483 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	417	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

NFIB_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.009624 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	O00712, O00166, Q12858, Q96J45	Gene names	NFIB
Domain Architecture
Description	Nuclear factor 1 B-type (Nuclear factor 1/B) (NF1-B) (NFI-B) (NF-I/B) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NFIB_MOUSE
θ value	8.99809 (rank : 18)	NC score	0.009554 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	P97863, P70252, P70253, P70254, Q9R1G4	Gene names	Nfib
Domain Architecture
Description	Nuclear factor 1 B-type (Nuclear factor 1/B) (NF1-B) (NFI-B) (NF-I/B) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

PRI1_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.012041 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	P20664	Gene names	Prim1
Domain Architecture
Description	DNA primase small subunit (EC 2.7.7.-) (DNA primase 49 kDa subunit) (p49).

RAB30_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.003722 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	Q15771, Q6FGK1, Q96CI8	Gene names	RAB30
Domain Architecture
Description	Ras-related protein Rab-30.

RAB30_MOUSE
θ value	8.99809 (rank : 21)	NC score	0.003722 (rank : 23)
Query Neighborhood Hits	22	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	Q923S9, Q3UQR3, Q9D3Q6	Gene names	Rab30, Rsb30
Domain Architecture	No domain graphic available
Description	Ras-related protein Rab-30.

TTK_HUMAN
θ value	8.99809 (rank : 22)	NC score	0.002115 (rank : 24)
Query Neighborhood Hits	22	Target Neighborhood Hits	816	Shared Neighborhood Hits	4
SwissProt Accessions	P33981	Gene names	TTK, MPS1L1
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT).

UQCR2_HUMAN
θ value	θ > 10 (rank : 23)	NC score	0.083166 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	P22695, Q9BQ05	Gene names	UQCRC2
Domain Architecture
Description	Ubiquinol-cytochrome-c reductase complex core protein 2, mitochondrial precursor (EC 1.10.2.2) (Complex III subunit II).

UQCR2_MOUSE
θ value	θ > 10 (rank : 24)	NC score	0.084719 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DB77	Gene names	Uqcrc2
Domain Architecture
Description	Ubiquinol-cytochrome-c reductase complex core protein 2, mitochondrial precursor (EC 1.10.2.2) (Complex III subunit II).

Hits sorted by NC score

IDE_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JHR7	Gene names	Ide
Domain Architecture
Description	Insulin-degrading enzyme (EC 3.4.24.56) (Insulysin) (Insulinase) (Insulin protease).

IDE_HUMAN
NC score	0.998956 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	23	Shared Neighborhood Hits	17
SwissProt Accessions	P14735	Gene names	IDE
Domain Architecture
Description	Insulin-degrading enzyme (EC 3.4.24.56) (Insulysin) (Insulinase) (Insulin protease).

NRDC_HUMAN
NC score	0.920621 (rank : 3)	θ value	5.22361e-149 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	60	Shared Neighborhood Hits	12
SwissProt Accessions	O43847, O15241, O15242, Q5VUL0, Q96HB2, Q9NU57	Gene names	NRD1
Domain Architecture
Description	Nardilysin precursor (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C).

NRDC_MOUSE
NC score	0.911024 (rank : 4)	θ value	2.26584e-152 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	96	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BHG1	Gene names	Nrd1
Domain Architecture
Description	Nardilysin precursor (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C).

MPPA_MOUSE
NC score	0.262144 (rank : 5)	θ value	0.000602161 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DC61, Q3TF19	Gene names	Pmpca, Inpp5e
Domain Architecture
Description	Mitochondrial-processing peptidase alpha subunit, mitochondrial precursor (EC 3.4.24.64) (Alpha-MPP) (P-55).

UQCR1_HUMAN
NC score	0.253612 (rank : 6)	θ value	0.000121331 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	P31930, Q96DD2	Gene names	UQCRC1
Domain Architecture
Description	Ubiquinol-cytochrome-c reductase complex core protein I, mitochondrial precursor (EC 1.10.2.2).

MPPB_HUMAN
NC score	0.253508 (rank : 7)	θ value	0.000158464 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	O75439, O60416, Q96FV4	Gene names	PMPCB, MPPB
Domain Architecture
Description	Mitochondrial-processing peptidase subunit beta, mitochondrial precursor (EC 3.4.24.64) (Beta-MPP) (P-52).

MPPA_HUMAN
NC score	0.234860 (rank : 8)	θ value	0.00228821 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q10713, Q16639, Q8N513	Gene names	PMPCA, KIAA0123, MPPA
Domain Architecture
Description	Mitochondrial-processing peptidase alpha subunit, mitochondrial precursor (EC 3.4.24.64) (Alpha-MPP) (P-55).

MPPB_MOUSE
NC score	0.234758 (rank : 9)	θ value	0.00228821 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CXT8	Gene names	Pmpcb
Domain Architecture
Description	Mitochondrial-processing peptidase subunit beta, mitochondrial precursor (EC 3.4.24.64) (Beta-MPP) (P-52).

UQCR1_MOUSE
NC score	0.230003 (rank : 10)	θ value	0.0193708 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CZ13, Q9CWL6	Gene names	Uqcrc1
Domain Architecture
Description	Ubiquinol-cytochrome-c reductase complex core protein I, mitochondrial precursor (EC 1.10.2.2).

PREP_HUMAN
NC score	0.135856 (rank : 11)	θ value	0.0431538 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q5JRX3, O95204, Q2M2G6, Q4VBR1, Q5JRW7, Q7L5Z7, Q9BSI6, Q9BVJ5, Q9UPP8	Gene names	PITRM1, KIAA1104, MP1
Domain Architecture	No domain graphic available
Description	Presequence protease, mitochondrial precursor (EC 3.4.24.-) (hPreP) (Pitrilysin metalloproteinase 1) (Metalloprotease 1) (hMP1).

PREP_MOUSE
NC score	0.123844 (rank : 12)	θ value	0.279714 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K411, Q3THC4, Q3TJI1, Q3TPP0, Q3URQ8, Q4KUG2, Q4KUG3, Q6ZPX6, Q922N1, Q9CV63	Gene names	Pitrm1, Kiaa1104, Ntup1
Domain Architecture	No domain graphic available
Description	Presequence protease, mitochondrial precursor (EC 3.4.24.-) (Pitrilysin metalloproteinase 1).

UQCR2_MOUSE
NC score	0.084719 (rank : 13)	θ value	θ > 10 (rank : 24)
Query Neighborhood Hits	22	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DB77	Gene names	Uqcrc2
Domain Architecture
Description	Ubiquinol-cytochrome-c reductase complex core protein 2, mitochondrial precursor (EC 1.10.2.2) (Complex III subunit II).

UQCR2_HUMAN
NC score	0.083166 (rank : 14)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	22	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	P22695, Q9BQ05	Gene names	UQCRC2
Domain Architecture
Description	Ubiquinol-cytochrome-c reductase complex core protein 2, mitochondrial precursor (EC 1.10.2.2) (Complex III subunit II).

4EBP1_MOUSE
NC score	0.019639 (rank : 15)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q60876, Q3TDS8, Q9CZ40	Gene names	Eif4ebp1
Domain Architecture
Description	Eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1) (eIF4E-binding protein 1) (Phosphorylated heat- and acid-stable protein regulated by insulin 1) (PHAS-I).

TTC16_HUMAN
NC score	0.018483 (rank : 16)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	417	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

PRI1_MOUSE
NC score	0.012041 (rank : 17)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	P20664	Gene names	Prim1
Domain Architecture
Description	DNA primase small subunit (EC 2.7.7.-) (DNA primase 49 kDa subunit) (p49).

MUCDL_MOUSE
NC score	0.011704 (rank : 18)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	461	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NFIB_HUMAN
NC score	0.009624 (rank : 19)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	O00712, O00166, Q12858, Q96J45	Gene names	NFIB
Domain Architecture
Description	Nuclear factor 1 B-type (Nuclear factor 1/B) (NF1-B) (NFI-B) (NF-I/B) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NFIB_MOUSE
NC score	0.009554 (rank : 20)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	P97863, P70252, P70253, P70254, Q9R1G4	Gene names	Nfib
Domain Architecture
Description	Nuclear factor 1 B-type (Nuclear factor 1/B) (NF1-B) (NFI-B) (NF-I/B) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

PCDGA_HUMAN
NC score	0.005813 (rank : 21)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	160	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5H3, Q9Y5E0	Gene names	PCDHGA10
Domain Architecture
Description	Protocadherin gamma A10 precursor (PCDH-gamma-A10).

RAB30_HUMAN
NC score	0.003722 (rank : 22)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	Q15771, Q6FGK1, Q96CI8	Gene names	RAB30
Domain Architecture
Description	Ras-related protein Rab-30.

RAB30_MOUSE
NC score	0.003722 (rank : 23)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	Q923S9, Q3UQR3, Q9D3Q6	Gene names	Rab30, Rsb30
Domain Architecture	No domain graphic available
Description	Ras-related protein Rab-30.

TTK_HUMAN
NC score	0.002115 (rank : 24)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	816	Shared Neighborhood Hits	4
SwissProt Accessions	P33981	Gene names	TTK, MPS1L1
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT).