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Network neighborhood for query Sequence : VPS45_HUMAN

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VPS45_HUMAN
SwissProt Accessions	Q9NRW7, Q15715, Q9Y4Z6	Gene names	VPS45A, VPS45
Domain Architecture
Description	Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

VPS45_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NRW7, Q15715, Q9Y4Z6	Gene names	VPS45A, VPS45
Domain Architecture
Description	Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45).

VPS45_MOUSE
θ value	0 (rank : 2)	NC score	0.998599 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	30	Shared Neighborhood Hits	21
SwissProt Accessions	P97390, Q91VK9	Gene names	Vps45a, Vps45
Domain Architecture
Description	Vacuolar protein sorting-associated protein 45 (mVps45).

STXB3_MOUSE
θ value	1.92365e-26 (rank : 3)	NC score	0.737561 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q60770	Gene names	Stxbp3, Stxbp3a, Unc18c
Domain Architecture
Description	Syntaxin-binding protein 3 (Unc-18 homolog 3) (Unc-18C) (MUNC-18-3).

STXB2_MOUSE
θ value	2.51237e-26 (rank : 4)	NC score	0.731738 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	Q64324	Gene names	Stxbp2, Unc18b
Domain Architecture
Description	Syntaxin-binding protein 2 (Unc-18 homolog 2) (Unc-18B) (MUSEC1).

STXB3_HUMAN
θ value	5.59698e-26 (rank : 5)	NC score	0.738223 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	O00186, Q86YJ3, Q9UPD7	Gene names	STXBP3
Domain Architecture
Description	Syntaxin-binding protein 3 (Unc-18 homolog 3) (Unc-18C) (Unc-18-3) (Platelet Sec1 protein) (PSP).

STXB2_HUMAN
θ value	7.30988e-26 (rank : 6)	NC score	0.734026 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	Q15833	Gene names	STXBP2, UNC18B
Domain Architecture
Description	Syntaxin-binding protein 2 (Unc-18 homolog 2) (Unc-18B) (Unc18-2).

SCFD1_HUMAN
θ value	3.62785e-25 (rank : 7)	NC score	0.722176 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WVM8, O60754, O94990, Q7Z529, Q9BZI3, Q9UNL3, Q9Y6A8	Gene names	SCFD1, KIAA0917, STXBP1L2
Domain Architecture	No domain graphic available
Description	Sec1 family domain-containing protein 1 (Syntaxin-binding protein 1- like 2) (Sly1p).

SCFD1_MOUSE
θ value	3.62785e-25 (rank : 8)	NC score	0.724635 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	35	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BRF7, Q8BRZ2, Q8K179, Q9CXR8	Gene names	Scfd1, Stxbp1l2
Domain Architecture	No domain graphic available
Description	Sec1 family domain-containing protein 1 (Syntaxin-binding protein 1- like 2).

STXB1_HUMAN
θ value	1.5773e-20 (rank : 9)	NC score	0.717669 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	P61764, Q28208, Q62759, Q64320, Q96TG8	Gene names	STXBP1, UNC18A
Domain Architecture
Description	Syntaxin-binding protein 1 (Unc-18 homolog) (Unc-18A) (Unc-18-1) (N- Sec1) (p67).

STXB1_MOUSE
θ value	1.5773e-20 (rank : 10)	NC score	0.717669 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	O08599, Q8VD51	Gene names	Stxbp1
Domain Architecture
Description	Syntaxin-binding protein 1 (Unc-18 homolog) (Unc-18A) (Unc-18-1).

VP33A_HUMAN
θ value	1.06045e-08 (rank : 11)	NC score	0.371290 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	24	Shared Neighborhood Hits	12
SwissProt Accessions	Q96AX1, Q9H5Q0	Gene names	VPS33A
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33A (hVPS33A).

VP33A_MOUSE
θ value	4.0297e-08 (rank : 12)	NC score	0.361167 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D2N9	Gene names	Vps33a
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33A.

REST_HUMAN
θ value	0.125558 (rank : 13)	NC score	0.020968 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	1605	Shared Neighborhood Hits	9
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

ATF6A_HUMAN
θ value	0.365318 (rank : 14)	NC score	0.055647 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

MMRN1_HUMAN
θ value	1.06291 (rank : 15)	NC score	0.031073 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	636	Shared Neighborhood Hits	9
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

CR034_MOUSE
θ value	1.81305 (rank : 16)	NC score	0.028622 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	643	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

GOGB1_HUMAN
θ value	5.27518 (rank : 17)	NC score	0.007501 (rank : 24)
Query Neighborhood Hits	22	Target Neighborhood Hits	2297	Shared Neighborhood Hits	11
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

REST_MOUSE
θ value	5.27518 (rank : 18)	NC score	0.013077 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	1506	Shared Neighborhood Hits	9
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

VPS54_HUMAN
θ value	5.27518 (rank : 19)	NC score	0.033226 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P1Q0, Q5VIR5, Q86YF7, Q8N6G3, Q9NPV0, Q9NT07, Q9NUJ0	Gene names	VPS54, HCC8
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p) (Hepatocellular carcinoma protein 8).

VPS54_MOUSE
θ value	5.27518 (rank : 20)	NC score	0.032529 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SPW0, Q8BPB3, Q8CFZ7, Q8CHL5, Q8R3R4, Q8R3X1	Gene names	Vps54
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p homolog).

KI13B_HUMAN
θ value	6.88961 (rank : 21)	NC score	0.008312 (rank : 23)
Query Neighborhood Hits	22	Target Neighborhood Hits	492	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

SGOL2_HUMAN
θ value	6.88961 (rank : 22)	NC score	0.025649 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	207	Shared Neighborhood Hits	7
SwissProt Accessions	Q562F6, Q53RR9, Q53T20, Q86XY4, Q8IWK2, Q8IZK1, Q8N1Q5, Q96LQ3	Gene names	SGOL2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2 (Tripin).

VP33B_HUMAN
θ value	θ > 10 (rank : 23)	NC score	0.123784 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H267, Q96K14, Q9NRP6, Q9NSF3	Gene names	VPS33B
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33B (hVPS33B).

VP33B_MOUSE
θ value	θ > 10 (rank : 24)	NC score	0.126381 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	P59016	Gene names	Vps33b
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33B.

Hits sorted by NC score

VPS45_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NRW7, Q15715, Q9Y4Z6	Gene names	VPS45A, VPS45
Domain Architecture
Description	Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45).

VPS45_MOUSE
NC score	0.998599 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	30	Shared Neighborhood Hits	21
SwissProt Accessions	P97390, Q91VK9	Gene names	Vps45a, Vps45
Domain Architecture
Description	Vacuolar protein sorting-associated protein 45 (mVps45).

STXB3_HUMAN
NC score	0.738223 (rank : 3)	θ value	5.59698e-26 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	O00186, Q86YJ3, Q9UPD7	Gene names	STXBP3
Domain Architecture
Description	Syntaxin-binding protein 3 (Unc-18 homolog 3) (Unc-18C) (Unc-18-3) (Platelet Sec1 protein) (PSP).

STXB3_MOUSE
NC score	0.737561 (rank : 4)	θ value	1.92365e-26 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q60770	Gene names	Stxbp3, Stxbp3a, Unc18c
Domain Architecture
Description	Syntaxin-binding protein 3 (Unc-18 homolog 3) (Unc-18C) (MUNC-18-3).

STXB2_HUMAN
NC score	0.734026 (rank : 5)	θ value	7.30988e-26 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	Q15833	Gene names	STXBP2, UNC18B
Domain Architecture
Description	Syntaxin-binding protein 2 (Unc-18 homolog 2) (Unc-18B) (Unc18-2).

STXB2_MOUSE
NC score	0.731738 (rank : 6)	θ value	2.51237e-26 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	Q64324	Gene names	Stxbp2, Unc18b
Domain Architecture
Description	Syntaxin-binding protein 2 (Unc-18 homolog 2) (Unc-18B) (MUSEC1).

SCFD1_MOUSE
NC score	0.724635 (rank : 7)	θ value	3.62785e-25 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	35	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BRF7, Q8BRZ2, Q8K179, Q9CXR8	Gene names	Scfd1, Stxbp1l2
Domain Architecture	No domain graphic available
Description	Sec1 family domain-containing protein 1 (Syntaxin-binding protein 1- like 2).

SCFD1_HUMAN
NC score	0.722176 (rank : 8)	θ value	3.62785e-25 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WVM8, O60754, O94990, Q7Z529, Q9BZI3, Q9UNL3, Q9Y6A8	Gene names	SCFD1, KIAA0917, STXBP1L2
Domain Architecture	No domain graphic available
Description	Sec1 family domain-containing protein 1 (Syntaxin-binding protein 1- like 2) (Sly1p).

STXB1_HUMAN
NC score	0.717669 (rank : 9)	θ value	1.5773e-20 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	P61764, Q28208, Q62759, Q64320, Q96TG8	Gene names	STXBP1, UNC18A
Domain Architecture
Description	Syntaxin-binding protein 1 (Unc-18 homolog) (Unc-18A) (Unc-18-1) (N- Sec1) (p67).

STXB1_MOUSE
NC score	0.717669 (rank : 10)	θ value	1.5773e-20 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	O08599, Q8VD51	Gene names	Stxbp1
Domain Architecture
Description	Syntaxin-binding protein 1 (Unc-18 homolog) (Unc-18A) (Unc-18-1).

VP33A_HUMAN
NC score	0.371290 (rank : 11)	θ value	1.06045e-08 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	24	Shared Neighborhood Hits	12
SwissProt Accessions	Q96AX1, Q9H5Q0	Gene names	VPS33A
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33A (hVPS33A).

VP33A_MOUSE
NC score	0.361167 (rank : 12)	θ value	4.0297e-08 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D2N9	Gene names	Vps33a
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33A.

VP33B_MOUSE
NC score	0.126381 (rank : 13)	θ value	θ > 10 (rank : 24)
Query Neighborhood Hits	22	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	P59016	Gene names	Vps33b
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33B.

VP33B_HUMAN
NC score	0.123784 (rank : 14)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	22	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H267, Q96K14, Q9NRP6, Q9NSF3	Gene names	VPS33B
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33B (hVPS33B).

ATF6A_HUMAN
NC score	0.055647 (rank : 15)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

VPS54_HUMAN
NC score	0.033226 (rank : 16)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P1Q0, Q5VIR5, Q86YF7, Q8N6G3, Q9NPV0, Q9NT07, Q9NUJ0	Gene names	VPS54, HCC8
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p) (Hepatocellular carcinoma protein 8).

VPS54_MOUSE
NC score	0.032529 (rank : 17)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SPW0, Q8BPB3, Q8CFZ7, Q8CHL5, Q8R3R4, Q8R3X1	Gene names	Vps54
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p homolog).

MMRN1_HUMAN
NC score	0.031073 (rank : 18)	θ value	1.06291 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	636	Shared Neighborhood Hits	9
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

CR034_MOUSE
NC score	0.028622 (rank : 19)	θ value	1.81305 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	643	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

SGOL2_HUMAN
NC score	0.025649 (rank : 20)	θ value	6.88961 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	207	Shared Neighborhood Hits	7
SwissProt Accessions	Q562F6, Q53RR9, Q53T20, Q86XY4, Q8IWK2, Q8IZK1, Q8N1Q5, Q96LQ3	Gene names	SGOL2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2 (Tripin).

REST_HUMAN
NC score	0.020968 (rank : 21)	θ value	0.125558 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	1605	Shared Neighborhood Hits	9
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

REST_MOUSE
NC score	0.013077 (rank : 22)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	1506	Shared Neighborhood Hits	9
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

KI13B_HUMAN
NC score	0.008312 (rank : 23)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	492	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

GOGB1_HUMAN
NC score	0.007501 (rank : 24)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	2297	Shared Neighborhood Hits	11
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).