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Network neighborhood for query Sequence : SCFD1_HUMAN

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SCFD1_HUMAN
SwissProt Accessions	Q8WVM8, O60754, O94990, Q7Z529, Q9BZI3, Q9UNL3, Q9Y6A8	Gene names	SCFD1, KIAA0917, STXBP1L2
Domain Architecture	No domain graphic available
Description	Sec1 family domain-containing protein 1 (Syntaxin-binding protein 1- like 2) (Sly1p).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SCFD1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WVM8, O60754, O94990, Q7Z529, Q9BZI3, Q9UNL3, Q9Y6A8	Gene names	SCFD1, KIAA0917, STXBP1L2
Domain Architecture	No domain graphic available
Description	Sec1 family domain-containing protein 1 (Syntaxin-binding protein 1- like 2) (Sly1p).

SCFD1_MOUSE
θ value	0 (rank : 2)	NC score	0.999590 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	35	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BRF7, Q8BRZ2, Q8K179, Q9CXR8	Gene names	Scfd1, Stxbp1l2
Domain Architecture	No domain graphic available
Description	Sec1 family domain-containing protein 1 (Syntaxin-binding protein 1- like 2).

VPS45_HUMAN
θ value	3.62785e-25 (rank : 3)	NC score	0.722176 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRW7, Q15715, Q9Y4Z6	Gene names	VPS45A, VPS45
Domain Architecture
Description	Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45).

VPS45_MOUSE
θ value	4.01107e-24 (rank : 4)	NC score	0.717488 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	P97390, Q91VK9	Gene names	Vps45a, Vps45
Domain Architecture
Description	Vacuolar protein sorting-associated protein 45 (mVps45).

STXB2_HUMAN
θ value	1.99529e-15 (rank : 5)	NC score	0.609785 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q15833	Gene names	STXBP2, UNC18B
Domain Architecture
Description	Syntaxin-binding protein 2 (Unc-18 homolog 2) (Unc-18B) (Unc18-2).

STXB2_MOUSE
θ value	4.44505e-15 (rank : 6)	NC score	0.606490 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q64324	Gene names	Stxbp2, Unc18b
Domain Architecture
Description	Syntaxin-binding protein 2 (Unc-18 homolog 2) (Unc-18B) (MUSEC1).

STXB3_HUMAN
θ value	6.41864e-14 (rank : 7)	NC score	0.598499 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	O00186, Q86YJ3, Q9UPD7	Gene names	STXBP3
Domain Architecture
Description	Syntaxin-binding protein 3 (Unc-18 homolog 3) (Unc-18C) (Unc-18-3) (Platelet Sec1 protein) (PSP).

STXB3_MOUSE
θ value	1.42992e-13 (rank : 8)	NC score	0.596597 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q60770	Gene names	Stxbp3, Stxbp3a, Unc18c
Domain Architecture
Description	Syntaxin-binding protein 3 (Unc-18 homolog 3) (Unc-18C) (MUNC-18-3).

STXB1_HUMAN
θ value	7.09661e-13 (rank : 9)	NC score	0.589623 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	P61764, Q28208, Q62759, Q64320, Q96TG8	Gene names	STXBP1, UNC18A
Domain Architecture
Description	Syntaxin-binding protein 1 (Unc-18 homolog) (Unc-18A) (Unc-18-1) (N- Sec1) (p67).

STXB1_MOUSE
θ value	7.09661e-13 (rank : 10)	NC score	0.589623 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	O08599, Q8VD51	Gene names	Stxbp1
Domain Architecture
Description	Syntaxin-binding protein 1 (Unc-18 homolog) (Unc-18A) (Unc-18-1).

VP33A_HUMAN
θ value	0.00102713 (rank : 11)	NC score	0.270649 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	24	Shared Neighborhood Hits	12
SwissProt Accessions	Q96AX1, Q9H5Q0	Gene names	VPS33A
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33A (hVPS33A).

VP33A_MOUSE
θ value	0.00228821 (rank : 12)	NC score	0.260259 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D2N9	Gene names	Vps33a
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33A.

DYNA_HUMAN
θ value	0.0961366 (rank : 13)	NC score	0.050092 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	1194	Shared Neighborhood Hits	21
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

DYNA_MOUSE
θ value	0.0961366 (rank : 14)	NC score	0.050983 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	1084	Shared Neighborhood Hits	18
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

LAMA3_HUMAN
θ value	0.813845 (rank : 15)	NC score	0.024046 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	760	Shared Neighborhood Hits	18
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

RAI14_MOUSE
θ value	1.38821 (rank : 16)	NC score	0.019143 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	1505	Shared Neighborhood Hits	20
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

CIZ1_HUMAN
θ value	1.81305 (rank : 17)	NC score	0.042770 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	359	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

GOGA4_HUMAN
θ value	1.81305 (rank : 18)	NC score	0.019053 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	2034	Shared Neighborhood Hits	21
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

PHAR1_HUMAN
θ value	1.81305 (rank : 19)	NC score	0.047508 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q9C0D0, Q3MJ93, Q5JSJ2	Gene names	PHACTR1, KIAA1733, RPEL1
Domain Architecture
Description	Phosphatase and actin regulator 1.

PHAR1_MOUSE
θ value	2.36792 (rank : 20)	NC score	0.045323 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	Q2M3X8, Q80VL9, Q8C873	Gene names	Phactr1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 1.

CCNB3_HUMAN
θ value	3.0926 (rank : 21)	NC score	0.025918 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	368	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

MYH11_HUMAN
θ value	3.0926 (rank : 22)	NC score	0.012512 (rank : 37)
Query Neighborhood Hits	36	Target Neighborhood Hits	1806	Shared Neighborhood Hits	22
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

WBP11_MOUSE
θ value	3.0926 (rank : 23)	NC score	0.028580 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	362	Shared Neighborhood Hits	5
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

AKA12_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.023799 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	825	Shared Neighborhood Hits	12
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

GOGB1_HUMAN
θ value	4.03905 (rank : 25)	NC score	0.017743 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	2297	Shared Neighborhood Hits	25
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

BRE1B_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.025222 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	1040	Shared Neighborhood Hits	19
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	5.27518 (rank : 27)	NC score	0.024523 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	970	Shared Neighborhood Hits	19
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

GOGA2_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.021874 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	856	Shared Neighborhood Hits	19
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

HOOK3_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.020440 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	1070	Shared Neighborhood Hits	18
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

HOOK3_MOUSE
θ value	5.27518 (rank : 30)	NC score	0.020891 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	1007	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

GRAP1_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.018057 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	944	Shared Neighborhood Hits	20
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

CAC2D_MOUSE
θ value	8.99809 (rank : 32)	NC score	0.016459 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	O08532, O08533, O08534, O08535, O08536	Gene names	Cacna2d1, Cacna2
Domain Architecture
Description	Dihydropyridine-sensitive L-type calcium channel subunits alpha- 2/delta precursor [Contains: L-type calcium channel subunit alpha-2; L-type calcium channel subunit delta].

CE290_HUMAN
θ value	8.99809 (rank : 33)	NC score	0.015997 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	1553	Shared Neighborhood Hits	20
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CROCC_MOUSE
θ value	8.99809 (rank : 34)	NC score	0.014105 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	1460	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

NOE1_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.011723 (rank : 38)
Query Neighborhood Hits	36	Target Neighborhood Hits	266	Shared Neighborhood Hits	13
SwissProt Accessions	Q99784, Q969S7, Q99452	Gene names	OLFM1, NOE1, NOEL1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1).

RAI14_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.013726 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	1367	Shared Neighborhood Hits	21
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

VP33B_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.080975 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H267, Q96K14, Q9NRP6, Q9NSF3	Gene names	VPS33B
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33B (hVPS33B).

VP33B_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.082789 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	P59016	Gene names	Vps33b
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33B.

Hits sorted by NC score

SCFD1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WVM8, O60754, O94990, Q7Z529, Q9BZI3, Q9UNL3, Q9Y6A8	Gene names	SCFD1, KIAA0917, STXBP1L2
Domain Architecture	No domain graphic available
Description	Sec1 family domain-containing protein 1 (Syntaxin-binding protein 1- like 2) (Sly1p).

SCFD1_MOUSE
NC score	0.999590 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	35	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BRF7, Q8BRZ2, Q8K179, Q9CXR8	Gene names	Scfd1, Stxbp1l2
Domain Architecture	No domain graphic available
Description	Sec1 family domain-containing protein 1 (Syntaxin-binding protein 1- like 2).

VPS45_HUMAN
NC score	0.722176 (rank : 3)	θ value	3.62785e-25 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRW7, Q15715, Q9Y4Z6	Gene names	VPS45A, VPS45
Domain Architecture
Description	Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45).

VPS45_MOUSE
NC score	0.717488 (rank : 4)	θ value	4.01107e-24 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	P97390, Q91VK9	Gene names	Vps45a, Vps45
Domain Architecture
Description	Vacuolar protein sorting-associated protein 45 (mVps45).

STXB2_HUMAN
NC score	0.609785 (rank : 5)	θ value	1.99529e-15 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q15833	Gene names	STXBP2, UNC18B
Domain Architecture
Description	Syntaxin-binding protein 2 (Unc-18 homolog 2) (Unc-18B) (Unc18-2).

STXB2_MOUSE
NC score	0.606490 (rank : 6)	θ value	4.44505e-15 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q64324	Gene names	Stxbp2, Unc18b
Domain Architecture
Description	Syntaxin-binding protein 2 (Unc-18 homolog 2) (Unc-18B) (MUSEC1).

STXB3_HUMAN
NC score	0.598499 (rank : 7)	θ value	6.41864e-14 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	O00186, Q86YJ3, Q9UPD7	Gene names	STXBP3
Domain Architecture
Description	Syntaxin-binding protein 3 (Unc-18 homolog 3) (Unc-18C) (Unc-18-3) (Platelet Sec1 protein) (PSP).

STXB3_MOUSE
NC score	0.596597 (rank : 8)	θ value	1.42992e-13 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q60770	Gene names	Stxbp3, Stxbp3a, Unc18c
Domain Architecture
Description	Syntaxin-binding protein 3 (Unc-18 homolog 3) (Unc-18C) (MUNC-18-3).

STXB1_HUMAN
NC score	0.589623 (rank : 9)	θ value	7.09661e-13 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	P61764, Q28208, Q62759, Q64320, Q96TG8	Gene names	STXBP1, UNC18A
Domain Architecture
Description	Syntaxin-binding protein 1 (Unc-18 homolog) (Unc-18A) (Unc-18-1) (N- Sec1) (p67).

STXB1_MOUSE
NC score	0.589623 (rank : 10)	θ value	7.09661e-13 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	O08599, Q8VD51	Gene names	Stxbp1
Domain Architecture
Description	Syntaxin-binding protein 1 (Unc-18 homolog) (Unc-18A) (Unc-18-1).

VP33A_HUMAN
NC score	0.270649 (rank : 11)	θ value	0.00102713 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	24	Shared Neighborhood Hits	12
SwissProt Accessions	Q96AX1, Q9H5Q0	Gene names	VPS33A
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33A (hVPS33A).

VP33A_MOUSE
NC score	0.260259 (rank : 12)	θ value	0.00228821 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D2N9	Gene names	Vps33a
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33A.

VP33B_MOUSE
NC score	0.082789 (rank : 13)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	36	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	P59016	Gene names	Vps33b
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33B.

VP33B_HUMAN
NC score	0.080975 (rank : 14)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	36	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H267, Q96K14, Q9NRP6, Q9NSF3	Gene names	VPS33B
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33B (hVPS33B).

DYNA_MOUSE
NC score	0.050983 (rank : 15)	θ value	0.0961366 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	1084	Shared Neighborhood Hits	18
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

DYNA_HUMAN
NC score	0.050092 (rank : 16)	θ value	0.0961366 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	1194	Shared Neighborhood Hits	21
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

PHAR1_HUMAN
NC score	0.047508 (rank : 17)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q9C0D0, Q3MJ93, Q5JSJ2	Gene names	PHACTR1, KIAA1733, RPEL1
Domain Architecture
Description	Phosphatase and actin regulator 1.

PHAR1_MOUSE
NC score	0.045323 (rank : 18)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	Q2M3X8, Q80VL9, Q8C873	Gene names	Phactr1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 1.

CIZ1_HUMAN
NC score	0.042770 (rank : 19)	θ value	1.81305 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	359	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

WBP11_MOUSE
NC score	0.028580 (rank : 20)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	362	Shared Neighborhood Hits	5
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

CCNB3_HUMAN
NC score	0.025918 (rank : 21)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	368	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

BRE1B_HUMAN
NC score	0.025222 (rank : 22)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	1040	Shared Neighborhood Hits	19
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
NC score	0.024523 (rank : 23)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	970	Shared Neighborhood Hits	19
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

LAMA3_HUMAN
NC score	0.024046 (rank : 24)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	760	Shared Neighborhood Hits	18
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

AKA12_HUMAN
NC score	0.023799 (rank : 25)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	825	Shared Neighborhood Hits	12
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

GOGA2_HUMAN
NC score	0.021874 (rank : 26)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	856	Shared Neighborhood Hits	19
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

HOOK3_MOUSE
NC score	0.020891 (rank : 27)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	1007	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

HOOK3_HUMAN
NC score	0.020440 (rank : 28)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	1070	Shared Neighborhood Hits	18
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

RAI14_MOUSE
NC score	0.019143 (rank : 29)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	1505	Shared Neighborhood Hits	20
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

GOGA4_HUMAN
NC score	0.019053 (rank : 30)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	2034	Shared Neighborhood Hits	21
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

GRAP1_HUMAN
NC score	0.018057 (rank : 31)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	944	Shared Neighborhood Hits	20
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

GOGB1_HUMAN
NC score	0.017743 (rank : 32)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	2297	Shared Neighborhood Hits	25
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CAC2D_MOUSE
NC score	0.016459 (rank : 33)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	O08532, O08533, O08534, O08535, O08536	Gene names	Cacna2d1, Cacna2
Domain Architecture
Description	Dihydropyridine-sensitive L-type calcium channel subunits alpha- 2/delta precursor [Contains: L-type calcium channel subunit alpha-2; L-type calcium channel subunit delta].

CE290_HUMAN
NC score	0.015997 (rank : 34)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	1553	Shared Neighborhood Hits	20
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CROCC_MOUSE
NC score	0.014105 (rank : 35)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	1460	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

RAI14_HUMAN
NC score	0.013726 (rank : 36)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	1367	Shared Neighborhood Hits	21
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

MYH11_HUMAN
NC score	0.012512 (rank : 37)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	1806	Shared Neighborhood Hits	22
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NOE1_HUMAN
NC score	0.011723 (rank : 38)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	266	Shared Neighborhood Hits	13
SwissProt Accessions	Q99784, Q969S7, Q99452	Gene names	OLFM1, NOE1, NOEL1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1).