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Network neighborhood for query Sequence : STXB2_HUMAN

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STXB2_HUMAN
SwissProt Accessions	Q15833	Gene names	STXBP2, UNC18B
Domain Architecture
Description	Syntaxin-binding protein 2 (Unc-18 homolog 2) (Unc-18B) (Unc18-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

STXB1_HUMAN
θ value	0 (rank : 1)	NC score	0.987476 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	P61764, Q28208, Q62759, Q64320, Q96TG8	Gene names	STXBP1, UNC18A
Domain Architecture
Description	Syntaxin-binding protein 1 (Unc-18 homolog) (Unc-18A) (Unc-18-1) (N- Sec1) (p67).

STXB1_MOUSE
θ value	0 (rank : 2)	NC score	0.987476 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	O08599, Q8VD51	Gene names	Stxbp1
Domain Architecture
Description	Syntaxin-binding protein 1 (Unc-18 homolog) (Unc-18A) (Unc-18-1).

STXB2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	Q15833	Gene names	STXBP2, UNC18B
Domain Architecture
Description	Syntaxin-binding protein 2 (Unc-18 homolog 2) (Unc-18B) (Unc18-2).

STXB2_MOUSE
θ value	0 (rank : 4)	NC score	0.999090 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	Q64324	Gene names	Stxbp2, Unc18b
Domain Architecture
Description	Syntaxin-binding protein 2 (Unc-18 homolog 2) (Unc-18B) (MUSEC1).

STXB3_MOUSE
θ value	1.79534e-149 (rank : 5)	NC score	0.975922 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q60770	Gene names	Stxbp3, Stxbp3a, Unc18c
Domain Architecture
Description	Syntaxin-binding protein 3 (Unc-18 homolog 3) (Unc-18C) (MUNC-18-3).

STXB3_HUMAN
θ value	6.82227e-149 (rank : 6)	NC score	0.975063 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	O00186, Q86YJ3, Q9UPD7	Gene names	STXBP3
Domain Architecture
Description	Syntaxin-binding protein 3 (Unc-18 homolog 3) (Unc-18C) (Unc-18-3) (Platelet Sec1 protein) (PSP).

VPS45_MOUSE
θ value	2.27234e-27 (rank : 7)	NC score	0.737692 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	P97390, Q91VK9	Gene names	Vps45a, Vps45
Domain Architecture
Description	Vacuolar protein sorting-associated protein 45 (mVps45).

VPS45_HUMAN
θ value	7.30988e-26 (rank : 8)	NC score	0.734026 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NRW7, Q15715, Q9Y4Z6	Gene names	VPS45A, VPS45
Domain Architecture
Description	Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45).

SCFD1_MOUSE
θ value	1.63225e-17 (rank : 9)	NC score	0.616815 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	35	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BRF7, Q8BRZ2, Q8K179, Q9CXR8	Gene names	Scfd1, Stxbp1l2
Domain Architecture	No domain graphic available
Description	Sec1 family domain-containing protein 1 (Syntaxin-binding protein 1- like 2).

SCFD1_HUMAN
θ value	1.99529e-15 (rank : 10)	NC score	0.609785 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WVM8, O60754, O94990, Q7Z529, Q9BZI3, Q9UNL3, Q9Y6A8	Gene names	SCFD1, KIAA0917, STXBP1L2
Domain Architecture	No domain graphic available
Description	Sec1 family domain-containing protein 1 (Syntaxin-binding protein 1- like 2) (Sly1p).

VP33B_MOUSE
θ value	2.21117e-06 (rank : 11)	NC score	0.191238 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	P59016	Gene names	Vps33b
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33B.

VP33B_HUMAN
θ value	8.40245e-06 (rank : 12)	NC score	0.186437 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H267, Q96K14, Q9NRP6, Q9NSF3	Gene names	VPS33B
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33B (hVPS33B).

VP33A_MOUSE
θ value	0.0431538 (rank : 13)	NC score	0.279343 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D2N9	Gene names	Vps33a
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33A.

VP33A_HUMAN
θ value	0.125558 (rank : 14)	NC score	0.285110 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	Q96AX1, Q9H5Q0	Gene names	VPS33A
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33A (hVPS33A).

CE290_HUMAN
θ value	1.06291 (rank : 15)	NC score	0.009452 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	1553	Shared Neighborhood Hits	10
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

SM1L2_HUMAN
θ value	1.81305 (rank : 16)	NC score	0.010112 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	1019	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

EXOC7_MOUSE
θ value	3.0926 (rank : 17)	NC score	0.027013 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	O35250, Q8K121	Gene names	Exoc7, Exo70
Domain Architecture
Description	Exocyst complex component 7 (Exocyst complex component Exo70).

LRRK2_MOUSE
θ value	3.0926 (rank : 18)	NC score	0.000129 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	1359	Shared Neighborhood Hits	2
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

C8AP2_HUMAN
θ value	4.03905 (rank : 19)	NC score	0.016048 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	548	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

BPA1_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.002790 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	1477	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_MOUSE
θ value	8.99809 (rank : 21)	NC score	0.002560 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	1480	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

EXOC6_MOUSE
θ value	8.99809 (rank : 22)	NC score	0.012722 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R313	Gene names	Exoc6, Sec15a, Sec15l1
Domain Architecture
Description	Exocyst complex component 6 (Exocyst complex component Sec15A) (Sec15- like 1).

MYO5C_HUMAN
θ value	8.99809 (rank : 23)	NC score	0.002135 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	1206	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

NOTC3_HUMAN
θ value	8.99809 (rank : 24)	NC score	-0.000699 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	1062	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

USBP1_HUMAN
θ value	8.99809 (rank : 25)	NC score	0.008134 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N6Y0, Q8NBX7, Q96KH3, Q9BYI8	Gene names	USHBP1, AIEBP, MCC2
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1) (MCC-2) (AIE-75 binding protein).

Hits sorted by NC score

STXB2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	Q15833	Gene names	STXBP2, UNC18B
Domain Architecture
Description	Syntaxin-binding protein 2 (Unc-18 homolog 2) (Unc-18B) (Unc18-2).

STXB2_MOUSE
NC score	0.999090 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	Q64324	Gene names	Stxbp2, Unc18b
Domain Architecture
Description	Syntaxin-binding protein 2 (Unc-18 homolog 2) (Unc-18B) (MUSEC1).

STXB1_HUMAN
NC score	0.987476 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	P61764, Q28208, Q62759, Q64320, Q96TG8	Gene names	STXBP1, UNC18A
Domain Architecture
Description	Syntaxin-binding protein 1 (Unc-18 homolog) (Unc-18A) (Unc-18-1) (N- Sec1) (p67).

STXB1_MOUSE
NC score	0.987476 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	O08599, Q8VD51	Gene names	Stxbp1
Domain Architecture
Description	Syntaxin-binding protein 1 (Unc-18 homolog) (Unc-18A) (Unc-18-1).

STXB3_MOUSE
NC score	0.975922 (rank : 5)	θ value	1.79534e-149 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q60770	Gene names	Stxbp3, Stxbp3a, Unc18c
Domain Architecture
Description	Syntaxin-binding protein 3 (Unc-18 homolog 3) (Unc-18C) (MUNC-18-3).

STXB3_HUMAN
NC score	0.975063 (rank : 6)	θ value	6.82227e-149 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	O00186, Q86YJ3, Q9UPD7	Gene names	STXBP3
Domain Architecture
Description	Syntaxin-binding protein 3 (Unc-18 homolog 3) (Unc-18C) (Unc-18-3) (Platelet Sec1 protein) (PSP).

VPS45_MOUSE
NC score	0.737692 (rank : 7)	θ value	2.27234e-27 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	P97390, Q91VK9	Gene names	Vps45a, Vps45
Domain Architecture
Description	Vacuolar protein sorting-associated protein 45 (mVps45).

VPS45_HUMAN
NC score	0.734026 (rank : 8)	θ value	7.30988e-26 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NRW7, Q15715, Q9Y4Z6	Gene names	VPS45A, VPS45
Domain Architecture
Description	Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45).

SCFD1_MOUSE
NC score	0.616815 (rank : 9)	θ value	1.63225e-17 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	35	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BRF7, Q8BRZ2, Q8K179, Q9CXR8	Gene names	Scfd1, Stxbp1l2
Domain Architecture	No domain graphic available
Description	Sec1 family domain-containing protein 1 (Syntaxin-binding protein 1- like 2).

SCFD1_HUMAN
NC score	0.609785 (rank : 10)	θ value	1.99529e-15 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WVM8, O60754, O94990, Q7Z529, Q9BZI3, Q9UNL3, Q9Y6A8	Gene names	SCFD1, KIAA0917, STXBP1L2
Domain Architecture	No domain graphic available
Description	Sec1 family domain-containing protein 1 (Syntaxin-binding protein 1- like 2) (Sly1p).

VP33A_HUMAN
NC score	0.285110 (rank : 11)	θ value	0.125558 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	Q96AX1, Q9H5Q0	Gene names	VPS33A
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33A (hVPS33A).

VP33A_MOUSE
NC score	0.279343 (rank : 12)	θ value	0.0431538 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D2N9	Gene names	Vps33a
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33A.

VP33B_MOUSE
NC score	0.191238 (rank : 13)	θ value	2.21117e-06 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	P59016	Gene names	Vps33b
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33B.

VP33B_HUMAN
NC score	0.186437 (rank : 14)	θ value	8.40245e-06 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H267, Q96K14, Q9NRP6, Q9NSF3	Gene names	VPS33B
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33B (hVPS33B).

EXOC7_MOUSE
NC score	0.027013 (rank : 15)	θ value	3.0926 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	O35250, Q8K121	Gene names	Exoc7, Exo70
Domain Architecture
Description	Exocyst complex component 7 (Exocyst complex component Exo70).

C8AP2_HUMAN
NC score	0.016048 (rank : 16)	θ value	4.03905 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	548	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

EXOC6_MOUSE
NC score	0.012722 (rank : 17)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R313	Gene names	Exoc6, Sec15a, Sec15l1
Domain Architecture
Description	Exocyst complex component 6 (Exocyst complex component Sec15A) (Sec15- like 1).

SM1L2_HUMAN
NC score	0.010112 (rank : 18)	θ value	1.81305 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	1019	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

CE290_HUMAN
NC score	0.009452 (rank : 19)	θ value	1.06291 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	1553	Shared Neighborhood Hits	10
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

USBP1_HUMAN
NC score	0.008134 (rank : 20)	θ value	8.99809 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N6Y0, Q8NBX7, Q96KH3, Q9BYI8	Gene names	USHBP1, AIEBP, MCC2
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1) (MCC-2) (AIE-75 binding protein).

BPA1_MOUSE
NC score	0.002790 (rank : 21)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	1477	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_MOUSE
NC score	0.002560 (rank : 22)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	1480	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MYO5C_HUMAN
NC score	0.002135 (rank : 23)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	1206	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

LRRK2_MOUSE
NC score	0.000129 (rank : 24)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	1359	Shared Neighborhood Hits	2
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

NOTC3_HUMAN
NC score	-0.000699 (rank : 25)	θ value	8.99809 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	1062	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].