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Network neighborhood for query Sequence : SERA_HUMAN

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SERA_HUMAN
SwissProt Accessions	O43175, Q5SZU3, Q9BQ01	Gene names	PHGDH, PGDH3
Domain Architecture
Description	D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SERA_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	O43175, Q5SZU3, Q9BQ01	Gene names	PHGDH, PGDH3
Domain Architecture
Description	D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH).

SERA_MOUSE
θ value	0 (rank : 2)	NC score	0.999516 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	17
SwissProt Accessions	Q61753, Q75SV9	Gene names	Phgdh
Domain Architecture	No domain graphic available
Description	D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH) (A10).

GRHPR_MOUSE
θ value	8.06329e-33 (rank : 3)	NC score	0.825056 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q91Z53	Gene names	Grhpr, Glxr
Domain Architecture
Description	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79).

CTBP1_HUMAN
θ value	4.42448e-31 (rank : 4)	NC score	0.775145 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q13363	Gene names	CTBP1, CTBP
Domain Architecture
Description	C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1).

CTBP1_MOUSE
θ value	5.77852e-31 (rank : 5)	NC score	0.774662 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	O88712, Q9QYG2	Gene names	Ctbp1
Domain Architecture
Description	C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1).

GRHPR_HUMAN
θ value	5.77852e-31 (rank : 6)	NC score	0.818895 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UBQ7, Q9H3E9, Q9UKX1	Gene names	GRHPR, GLXR
Domain Architecture
Description	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79).

CTBP2_HUMAN
θ value	7.80994e-28 (rank : 7)	NC score	0.761338 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	P56545, O43449	Gene names	CTBP2
Domain Architecture
Description	C-terminal-binding protein 2 (CtBP2).

CTBP2_MOUSE
θ value	7.80994e-28 (rank : 8)	NC score	0.760508 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	33	Shared Neighborhood Hits	8
SwissProt Accessions	P56546, O54855, O88462	Gene names	Ctbp2
Domain Architecture
Description	C-terminal-binding protein 2 (CtBP2).

HBS1L_MOUSE
θ value	1.81305 (rank : 9)	NC score	0.027062 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q69ZS7, Q91Z32, Q9CVT2, Q9CZ95, Q9WTY5	Gene names	Hbs1l, Hbs1, Kiaa1038
Domain Architecture	No domain graphic available
Description	HBS1-like protein.

G3PT_HUMAN
θ value	2.36792 (rank : 10)	NC score	0.038232 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	O14556, O60823, Q6JTT9, Q9HCU6	Gene names	GAPDHS, GAPD2, GAPDH2, GAPDS
Domain Architecture
Description	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2).

ABCA6_MOUSE
θ value	5.27518 (rank : 11)	NC score	0.010477 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K441, Q8BGH0, Q8BPT1	Gene names	Abca6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

LAMA5_HUMAN
θ value	5.27518 (rank : 12)	NC score	0.003690 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	976	Shared Neighborhood Hits	2
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

NSMA2_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.022278 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NY59	Gene names	SMPD3
Domain Architecture	No domain graphic available
Description	Sphingomyelin phosphodiesterase 3 (EC 3.1.4.12) (Neutral sphingomyelinase 2) (Neutral sphingomyelinase II) (nSMase2) (nSMase- 2).

CN004_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.025480 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H1B7, Q8NDQ2, Q96JG2, Q9H3I7	Gene names	C14orf4, KIAA1865
Domain Architecture	No domain graphic available
Description	Protein C14orf4.

CN004_MOUSE
θ value	8.99809 (rank : 15)	NC score	0.025067 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K3X4, Q3USE5, Q8BUS1, Q8C011	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf4 homolog.

G3PT_MOUSE
θ value	8.99809 (rank : 16)	NC score	0.025240 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	Q64467, Q60650	Gene names	Gapdhs, Gapd-s, Gapds
Domain Architecture
Description	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2).

HBS1L_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.015881 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y450, Q5T7G3, Q8NDW9, Q9UPW3	Gene names	HBS1L, HBS1, KIAA1038
Domain Architecture	No domain graphic available
Description	HBS1-like protein (ERFS).

NEDD1_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.010386 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	294	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NHV4, Q8NA30	Gene names	NEDD1
Domain Architecture	No domain graphic available
Description	Protein NEDD1.

WNK1_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.002217 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	1179	Shared Neighborhood Hits	3
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

Hits sorted by NC score

SERA_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	O43175, Q5SZU3, Q9BQ01	Gene names	PHGDH, PGDH3
Domain Architecture
Description	D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH).

SERA_MOUSE
NC score	0.999516 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	17
SwissProt Accessions	Q61753, Q75SV9	Gene names	Phgdh
Domain Architecture	No domain graphic available
Description	D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH) (A10).

GRHPR_MOUSE
NC score	0.825056 (rank : 3)	θ value	8.06329e-33 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q91Z53	Gene names	Grhpr, Glxr
Domain Architecture
Description	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79).

GRHPR_HUMAN
NC score	0.818895 (rank : 4)	θ value	5.77852e-31 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UBQ7, Q9H3E9, Q9UKX1	Gene names	GRHPR, GLXR
Domain Architecture
Description	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79).

CTBP1_HUMAN
NC score	0.775145 (rank : 5)	θ value	4.42448e-31 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q13363	Gene names	CTBP1, CTBP
Domain Architecture
Description	C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1).

CTBP1_MOUSE
NC score	0.774662 (rank : 6)	θ value	5.77852e-31 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	O88712, Q9QYG2	Gene names	Ctbp1
Domain Architecture
Description	C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1).

CTBP2_HUMAN
NC score	0.761338 (rank : 7)	θ value	7.80994e-28 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	P56545, O43449	Gene names	CTBP2
Domain Architecture
Description	C-terminal-binding protein 2 (CtBP2).

CTBP2_MOUSE
NC score	0.760508 (rank : 8)	θ value	7.80994e-28 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	33	Shared Neighborhood Hits	8
SwissProt Accessions	P56546, O54855, O88462	Gene names	Ctbp2
Domain Architecture
Description	C-terminal-binding protein 2 (CtBP2).

G3PT_HUMAN
NC score	0.038232 (rank : 9)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	O14556, O60823, Q6JTT9, Q9HCU6	Gene names	GAPDHS, GAPD2, GAPDH2, GAPDS
Domain Architecture
Description	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2).

HBS1L_MOUSE
NC score	0.027062 (rank : 10)	θ value	1.81305 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q69ZS7, Q91Z32, Q9CVT2, Q9CZ95, Q9WTY5	Gene names	Hbs1l, Hbs1, Kiaa1038
Domain Architecture	No domain graphic available
Description	HBS1-like protein.

CN004_HUMAN
NC score	0.025480 (rank : 11)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H1B7, Q8NDQ2, Q96JG2, Q9H3I7	Gene names	C14orf4, KIAA1865
Domain Architecture	No domain graphic available
Description	Protein C14orf4.

G3PT_MOUSE
NC score	0.025240 (rank : 12)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	Q64467, Q60650	Gene names	Gapdhs, Gapd-s, Gapds
Domain Architecture
Description	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2).

CN004_MOUSE
NC score	0.025067 (rank : 13)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K3X4, Q3USE5, Q8BUS1, Q8C011	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf4 homolog.

NSMA2_HUMAN
NC score	0.022278 (rank : 14)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NY59	Gene names	SMPD3
Domain Architecture	No domain graphic available
Description	Sphingomyelin phosphodiesterase 3 (EC 3.1.4.12) (Neutral sphingomyelinase 2) (Neutral sphingomyelinase II) (nSMase2) (nSMase- 2).

HBS1L_HUMAN
NC score	0.015881 (rank : 15)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y450, Q5T7G3, Q8NDW9, Q9UPW3	Gene names	HBS1L, HBS1, KIAA1038
Domain Architecture	No domain graphic available
Description	HBS1-like protein (ERFS).

ABCA6_MOUSE
NC score	0.010477 (rank : 16)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K441, Q8BGH0, Q8BPT1	Gene names	Abca6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

NEDD1_HUMAN
NC score	0.010386 (rank : 17)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	294	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NHV4, Q8NA30	Gene names	NEDD1
Domain Architecture	No domain graphic available
Description	Protein NEDD1.

LAMA5_HUMAN
NC score	0.003690 (rank : 18)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	976	Shared Neighborhood Hits	2
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

WNK1_MOUSE
NC score	0.002217 (rank : 19)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	1179	Shared Neighborhood Hits	3
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).