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Network neighborhood for query Sequence : PARVA_HUMAN

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PARVA_HUMAN
SwissProt Accessions	Q9NVD7, Q96C85, Q9HA48	Gene names	PARVA
Domain Architecture
Description	Alpha-parvin (Calponin-like integrin-linked kinase-binding protein) (CH-ILKBP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PARVA_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	63	Target Neighborhood Hits	63	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NVD7, Q96C85, Q9HA48	Gene names	PARVA
Domain Architecture
Description	Alpha-parvin (Calponin-like integrin-linked kinase-binding protein) (CH-ILKBP).

PARVA_MOUSE
θ value	0 (rank : 2)	NC score	0.998814 (rank : 2)
Query Neighborhood Hits	63	Target Neighborhood Hits	61	Shared Neighborhood Hits	55
SwissProt Accessions	Q9EPC1, Q9JJ65	Gene names	Parva, Actp
Domain Architecture
Description	Alpha-parvin (Actopaxin).

PARVB_HUMAN
θ value	1.98498e-148 (rank : 3)	NC score	0.991366 (rank : 3)
Query Neighborhood Hits	63	Target Neighborhood Hits	42	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HBI1, Q5TGJ5, Q86X93, Q9NSP7, Q9UGT3, Q9Y368, Q9Y3L6, Q9Y3L7	Gene names	PARVB
Domain Architecture
Description	Beta-parvin (Affixin).

PARVB_MOUSE
θ value	1.57279e-145 (rank : 4)	NC score	0.990471 (rank : 4)
Query Neighborhood Hits	63	Target Neighborhood Hits	43	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ES46	Gene names	Parvb
Domain Architecture
Description	Beta-parvin.

PARVG_HUMAN
θ value	5.00389e-67 (rank : 5)	NC score	0.935559 (rank : 6)
Query Neighborhood Hits	63	Target Neighborhood Hits	44	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HBI0, Q9BQX5, Q9NSG1	Gene names	PARVG
Domain Architecture
Description	Gamma-parvin.

PARVG_MOUSE
θ value	1.45591e-66 (rank : 6)	NC score	0.943989 (rank : 5)
Query Neighborhood Hits	63	Target Neighborhood Hits	41	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ERD8, Q91X89	Gene names	Parvg
Domain Architecture
Description	Gamma-parvin.

ACTN3_HUMAN
θ value	4.92598e-06 (rank : 7)	NC score	0.316117 (rank : 11)
Query Neighborhood Hits	63	Target Neighborhood Hits	272	Shared Neighborhood Hits	42
SwissProt Accessions	Q08043	Gene names	ACTN3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN3_MOUSE
θ value	4.92598e-06 (rank : 8)	NC score	0.315458 (rank : 12)
Query Neighborhood Hits	63	Target Neighborhood Hits	265	Shared Neighborhood Hits	46
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN2_HUMAN
θ value	1.87187e-05 (rank : 9)	NC score	0.311972 (rank : 13)
Query Neighborhood Hits	63	Target Neighborhood Hits	295	Shared Neighborhood Hits	45
SwissProt Accessions	P35609, Q86TF4, Q86TI8	Gene names	ACTN2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ACTN2_MOUSE
θ value	1.87187e-05 (rank : 10)	NC score	0.311926 (rank : 14)
Query Neighborhood Hits	63	Target Neighborhood Hits	287	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JI91	Gene names	Actn2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ACTN4_HUMAN
θ value	7.1131e-05 (rank : 11)	NC score	0.322326 (rank : 7)
Query Neighborhood Hits	63	Target Neighborhood Hits	279	Shared Neighborhood Hits	44
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN4_MOUSE
θ value	7.1131e-05 (rank : 12)	NC score	0.322083 (rank : 8)
Query Neighborhood Hits	63	Target Neighborhood Hits	276	Shared Neighborhood Hits	42
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN1_HUMAN
θ value	9.29e-05 (rank : 13)	NC score	0.318546 (rank : 10)
Query Neighborhood Hits	63	Target Neighborhood Hits	221	Shared Neighborhood Hits	36
SwissProt Accessions	P12814, Q9BTN1	Gene names	ACTN1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN1_MOUSE
θ value	9.29e-05 (rank : 14)	NC score	0.319119 (rank : 9)
Query Neighborhood Hits	63	Target Neighborhood Hits	216	Shared Neighborhood Hits	34
SwissProt Accessions	Q7TPR4	Gene names	Actn1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

FLNB_MOUSE
θ value	0.000461057 (rank : 15)	NC score	0.290903 (rank : 15)
Query Neighborhood Hits	63	Target Neighborhood Hits	126	Shared Neighborhood Hits	32
SwissProt Accessions	Q80X90, Q8VHX4, Q8VHX7, Q99KY3	Gene names	Flnb
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (ABP- 280-like protein).

MACF1_HUMAN
θ value	0.000786445 (rank : 16)	NC score	0.198854 (rank : 30)
Query Neighborhood Hits	63	Target Neighborhood Hits	1341	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF1_MOUSE
θ value	0.000786445 (rank : 17)	NC score	0.205299 (rank : 29)
Query Neighborhood Hits	63	Target Neighborhood Hits	1313	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

PLEC1_HUMAN
θ value	0.00134147 (rank : 18)	NC score	0.178366 (rank : 32)
Query Neighborhood Hits	63	Target Neighborhood Hits	1326	Shared Neighborhood Hits	51
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

SPTB2_HUMAN
θ value	0.00175202 (rank : 19)	NC score	0.238506 (rank : 26)
Query Neighborhood Hits	63	Target Neighborhood Hits	748	Shared Neighborhood Hits	51
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_MOUSE
θ value	0.00175202 (rank : 20)	NC score	0.237281 (rank : 27)
Query Neighborhood Hits	63	Target Neighborhood Hits	770	Shared Neighborhood Hits	51
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

BPA1_MOUSE
θ value	0.00390308 (rank : 21)	NC score	0.192351 (rank : 31)
Query Neighborhood Hits	63	Target Neighborhood Hits	1477	Shared Neighborhood Hits	54
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

FLNC_HUMAN
θ value	0.00390308 (rank : 22)	NC score	0.283671 (rank : 16)
Query Neighborhood Hits	63	Target Neighborhood Hits	116	Shared Neighborhood Hits	32
SwissProt Accessions	Q14315, O95303, Q07985, Q9NS12, Q9NYE5, Q9UMR8, Q9Y503	Gene names	FLNC, ABPL, FLN2
Domain Architecture
Description	Filamin-C (Gamma-filamin) (Filamin-2) (Protein FLNc) (Actin-binding- like protein) (ABP-L) (ABP-280-like protein).

FLNB_HUMAN
θ value	0.0113563 (rank : 23)	NC score	0.276089 (rank : 19)
Query Neighborhood Hits	63	Target Neighborhood Hits	111	Shared Neighborhood Hits	32
SwissProt Accessions	O75369, Q13706, Q8WXS9, Q8WXT0, Q8WXT1, Q8WXT2, Q9NRB5, Q9NT26, Q9UEV9	Gene names	FLNB, FLN1L, FLN3, TABP, TAP
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP) (ABP- 280 homolog) (ABP-278) (Filamin 3) (Filamin homolog 1) (Fh1).

SPTB1_HUMAN
θ value	0.0148317 (rank : 24)	NC score	0.246897 (rank : 23)
Query Neighborhood Hits	63	Target Neighborhood Hits	541	Shared Neighborhood Hits	48
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

FLNA_HUMAN
θ value	0.0252991 (rank : 25)	NC score	0.278019 (rank : 17)
Query Neighborhood Hits	63	Target Neighborhood Hits	138	Shared Neighborhood Hits	33
SwissProt Accessions	P21333	Gene names	FLNA, FLN, FLN1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

FLNA_MOUSE
θ value	0.0252991 (rank : 26)	NC score	0.277424 (rank : 18)
Query Neighborhood Hits	63	Target Neighborhood Hits	142	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BTM8, O54934, Q7TQI1, Q8BLK1, Q8BTN7, Q8VHX5, Q8VHX8, Q99KQ2	Gene names	Flna, Fln, Fln1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

SPTB1_MOUSE
θ value	0.0431538 (rank : 27)	NC score	0.241604 (rank : 25)
Query Neighborhood Hits	63	Target Neighborhood Hits	543	Shared Neighborhood Hits	49
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SPTN2_HUMAN
θ value	0.0431538 (rank : 28)	NC score	0.245211 (rank : 24)
Query Neighborhood Hits	63	Target Neighborhood Hits	535	Shared Neighborhood Hits	48
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

CLMN_MOUSE
θ value	0.0563607 (rank : 29)	NC score	0.270514 (rank : 20)
Query Neighborhood Hits	63	Target Neighborhood Hits	180	Shared Neighborhood Hits	32
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

CLMN_HUMAN
θ value	0.0736092 (rank : 30)	NC score	0.261088 (rank : 21)
Query Neighborhood Hits	63	Target Neighborhood Hits	205	Shared Neighborhood Hits	31
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

MD1L1_MOUSE
θ value	0.125558 (rank : 31)	NC score	0.063168 (rank : 63)
Query Neighborhood Hits	63	Target Neighborhood Hits	1001	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

SPTN4_HUMAN
θ value	0.125558 (rank : 32)	NC score	0.250849 (rank : 22)
Query Neighborhood Hits	63	Target Neighborhood Hits	570	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

GCC1_MOUSE
θ value	0.279714 (rank : 33)	NC score	0.046697 (rank : 73)
Query Neighborhood Hits	63	Target Neighborhood Hits	777	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

RABE1_HUMAN
θ value	0.365318 (rank : 34)	NC score	0.051248 (rank : 68)
Query Neighborhood Hits	63	Target Neighborhood Hits	1104	Shared Neighborhood Hits	35
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE1_MOUSE
θ value	0.365318 (rank : 35)	NC score	0.050876 (rank : 69)
Query Neighborhood Hits	63	Target Neighborhood Hits	1105	Shared Neighborhood Hits	36
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

MD1L1_HUMAN
θ value	0.62314 (rank : 36)	NC score	0.059618 (rank : 64)
Query Neighborhood Hits	63	Target Neighborhood Hits	893	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

MYH8_HUMAN
θ value	1.38821 (rank : 37)	NC score	0.039757 (rank : 77)
Query Neighborhood Hits	63	Target Neighborhood Hits	1610	Shared Neighborhood Hits	42
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

NUCB2_MOUSE
θ value	1.38821 (rank : 38)	NC score	0.037022 (rank : 79)
Query Neighborhood Hits	63	Target Neighborhood Hits	459	Shared Neighborhood Hits	20
SwissProt Accessions	P81117	Gene names	Nucb2, Nefa
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA).

SPTA2_HUMAN
θ value	1.38821 (rank : 39)	NC score	0.157499 (rank : 35)
Query Neighborhood Hits	63	Target Neighborhood Hits	888	Shared Neighborhood Hits	38
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

DYNA_HUMAN
θ value	1.81305 (rank : 40)	NC score	0.048985 (rank : 71)
Query Neighborhood Hits	63	Target Neighborhood Hits	1194	Shared Neighborhood Hits	41
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

DYNA_MOUSE
θ value	1.81305 (rank : 41)	NC score	0.047487 (rank : 72)
Query Neighborhood Hits	63	Target Neighborhood Hits	1084	Shared Neighborhood Hits	40
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

KIF3B_HUMAN
θ value	2.36792 (rank : 42)	NC score	0.017920 (rank : 86)
Query Neighborhood Hits	63	Target Neighborhood Hits	540	Shared Neighborhood Hits	29
SwissProt Accessions	O15066	Gene names	KIF3B, KIAA0359
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048).

KIF3B_MOUSE
θ value	2.36792 (rank : 43)	NC score	0.017601 (rank : 88)
Query Neighborhood Hits	63	Target Neighborhood Hits	533	Shared Neighborhood Hits	28
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

MYH1_MOUSE
θ value	2.36792 (rank : 44)	NC score	0.041963 (rank : 74)
Query Neighborhood Hits	63	Target Neighborhood Hits	1461	Shared Neighborhood Hits	44
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH2_HUMAN
θ value	2.36792 (rank : 45)	NC score	0.041784 (rank : 75)
Query Neighborhood Hits	63	Target Neighborhood Hits	1491	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

DYH11_HUMAN
θ value	3.0926 (rank : 46)	NC score	0.032407 (rank : 82)
Query Neighborhood Hits	63	Target Neighborhood Hits	234	Shared Neighborhood Hits	16
SwissProt Accessions	Q96DT5, Q9UJ82	Gene names	DNAH11
Domain Architecture
Description	Ciliary dynein heavy chain 11 (Axonemal beta dynein heavy chain 11).

K0562_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.027214 (rank : 84)
Query Neighborhood Hits	63	Target Neighborhood Hits	146	Shared Neighborhood Hits	8
SwissProt Accessions	O60308, Q5JSQ3, Q5SR24, Q5SR25, Q6PKF5, Q86W32, Q86X14	Gene names	KIAA0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

MY18B_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.035667 (rank : 80)
Query Neighborhood Hits	63	Target Neighborhood Hits	1299	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYH1_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.039712 (rank : 78)
Query Neighborhood Hits	63	Target Neighborhood Hits	1478	Shared Neighborhood Hits	41
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

EVI2B_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.022315 (rank : 85)
Query Neighborhood Hits	63	Target Neighborhood Hits	135	Shared Neighborhood Hits	3
SwissProt Accessions	P34910	Gene names	EVI2B, EVDB
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

NIN_MOUSE
θ value	5.27518 (rank : 51)	NC score	0.041504 (rank : 76)
Query Neighborhood Hits	63	Target Neighborhood Hits	1376	Shared Neighborhood Hits	37
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

TP53B_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.011671 (rank : 90)
Query Neighborhood Hits	63	Target Neighborhood Hits	413	Shared Neighborhood Hits	7
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

BMP6_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.003560 (rank : 92)
Query Neighborhood Hits	63	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	P22004	Gene names	BMP6, VGR
Domain Architecture
Description	Bone morphogenetic protein 6 precursor (BMP-6).

DMD_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.150168 (rank : 40)
Query Neighborhood Hits	63	Target Neighborhood Hits	1135	Shared Neighborhood Hits	51
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

SYNE1_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.145763 (rank : 43)
Query Neighborhood Hits	63	Target Neighborhood Hits	1484	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

BPAEA_MOUSE
θ value	8.99809 (rank : 56)	NC score	0.067055 (rank : 62)
Query Neighborhood Hits	63	Target Neighborhood Hits	1480	Shared Neighborhood Hits	39
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

GCC1_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.035175 (rank : 81)
Query Neighborhood Hits	63	Target Neighborhood Hits	887	Shared Neighborhood Hits	29
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

HAX1_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.017882 (rank : 87)
Query Neighborhood Hits	63	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	O00165, Q96AU4, Q9BS80	Gene names	HAX1, HS1BP1
Domain Architecture	No domain graphic available
Description	HS1-associating protein X-1 (HAX-1) (HS1-binding protein).

NBR1_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.013346 (rank : 89)
Query Neighborhood Hits	63	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	P97432, Q9JIH9	Gene names	Nbr1, M17s2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2).

PRS6A_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.002750 (rank : 93)
Query Neighborhood Hits	63	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	P17980, Q96HD3	Gene names	PSMC3, TBP1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1) (Proteasome subunit P50).

PTN21_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.001888 (rank : 94)
Query Neighborhood Hits	63	Target Neighborhood Hits	155	Shared Neighborhood Hits	3
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

SMC1A_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.031913 (rank : 83)
Query Neighborhood Hits	63	Target Neighborhood Hits	1346	Shared Neighborhood Hits	36
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

VASP_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.006503 (rank : 91)
Query Neighborhood Hits	63	Target Neighborhood Hits	195	Shared Neighborhood Hits	3
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

ASPM_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.113441 (rank : 50)
Query Neighborhood Hits	63	Target Neighborhood Hits	197	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IZT6, Q86UX4, Q8IUL2, Q8IZJ7, Q8IZJ8, Q8IZJ9, Q8N4D1, Q9NVS1, Q9NVT6	Gene names	ASPM, MCPH5
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog).

ASPM_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.114566 (rank : 49)
Query Neighborhood Hits	63	Target Neighborhood Hits	150	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CJ27, O88482, Q8BJI8, Q8BKT4	Gene names	Aspm, Calmbp1, Sha1
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein homolog (Calmodulin-binding protein 1) (Spindle and hydroxyurea checkpoint abnormal protein) (Calmodulin-binding protein Sha1).

BPAEA_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.104650 (rank : 56)
Query Neighborhood Hits	63	Target Neighborhood Hits	1369	Shared Neighborhood Hits	40
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CYTSA_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.094298 (rank : 60)
Query Neighborhood Hits	63	Target Neighborhood Hits	1138	Shared Neighborhood Hits	47
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CYTSA_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.091994 (rank : 61)
Query Neighborhood Hits	63	Target Neighborhood Hits	1104	Shared Neighborhood Hits	47
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

DESP_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.053417 (rank : 66)
Query Neighborhood Hits	63	Target Neighborhood Hits	1470	Shared Neighborhood Hits	40
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

DMD_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.146960 (rank : 42)
Query Neighborhood Hits	63	Target Neighborhood Hits	1111	Shared Neighborhood Hits	50
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

HAPIP_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.056770 (rank : 65)
Query Neighborhood Hits	63	Target Neighborhood Hits	350	Shared Neighborhood Hits	30
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

MACF4_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.098884 (rank : 58)
Query Neighborhood Hits	63	Target Neighborhood Hits	1321	Shared Neighborhood Hits	42
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MICA1_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.105502 (rank : 55)
Query Neighborhood Hits	63	Target Neighborhood Hits	279	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

MICA1_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.107741 (rank : 51)
Query Neighborhood Hits	63	Target Neighborhood Hits	400	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

MICA2_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.133189 (rank : 45)
Query Neighborhood Hits	63	Target Neighborhood Hits	174	Shared Neighborhood Hits	28
SwissProt Accessions	O94851, Q7Z3A8	Gene names	MICAL2, KIAA0750
Domain Architecture
Description	Protein MICAL-2.

MICA2_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.117804 (rank : 48)
Query Neighborhood Hits	63	Target Neighborhood Hits	144	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BML1, Q3UPU6	Gene names	Mical2
Domain Architecture
Description	Protein MICAL-2.

MICA3_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.122661 (rank : 47)
Query Neighborhood Hits	63	Target Neighborhood Hits	160	Shared Neighborhood Hits	24
SwissProt Accessions	Q7RTP6, Q6ICK4, Q9P2I3	Gene names	MICAL3, KIAA1364
Domain Architecture
Description	Protein MICAL-3.

MICA3_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.126597 (rank : 46)
Query Neighborhood Hits	63	Target Neighborhood Hits	104	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CJ19, Q80TE8, Q8BXB1	Gene names	Mical3, Kiaa1364
Domain Architecture
Description	Protein MICAL-3.

MILK1_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.151271 (rank : 39)
Query Neighborhood Hits	63	Target Neighborhood Hits	427	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MILK1_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.138695 (rank : 44)
Query Neighborhood Hits	63	Target Neighborhood Hits	788	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MILK2_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.154050 (rank : 37)
Query Neighborhood Hits	63	Target Neighborhood Hits	457	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

PEPL_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.050540 (rank : 70)
Query Neighborhood Hits	63	Target Neighborhood Hits	1141	Shared Neighborhood Hits	37
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PEPL_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.051303 (rank : 67)
Query Neighborhood Hits	63	Target Neighborhood Hits	1105	Shared Neighborhood Hits	38
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PLSI_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.095166 (rank : 59)
Query Neighborhood Hits	63	Target Neighborhood Hits	209	Shared Neighborhood Hits	29
SwissProt Accessions	Q14651	Gene names	PLS1
Domain Architecture
Description	Plastin-1 (I-plastin) (Intestine-specific plastin).

PLSL_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.104128 (rank : 57)
Query Neighborhood Hits	63	Target Neighborhood Hits	168	Shared Neighborhood Hits	28
SwissProt Accessions	P13796	Gene names	LCP1, PLS2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P).

PLSL_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.106385 (rank : 54)
Query Neighborhood Hits	63	Target Neighborhood Hits	170	Shared Neighborhood Hits	28
SwissProt Accessions	Q61233, Q3UE24, Q8R1X3, Q9CV77	Gene names	Lcp1, Pls2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (pp65).

PLST_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.106865 (rank : 53)
Query Neighborhood Hits	63	Target Neighborhood Hits	161	Shared Neighborhood Hits	27
SwissProt Accessions	P13797, Q86YI6	Gene names	PLS3
Domain Architecture
Description	Plastin-3 (T-plastin).

PLST_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.107083 (rank : 52)
Query Neighborhood Hits	63	Target Neighborhood Hits	156	Shared Neighborhood Hits	27
SwissProt Accessions	Q99K51	Gene names	Pls3
Domain Architecture	No domain graphic available
Description	Plastin-3 (T-plastin).

SMOO_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.162034 (rank : 33)
Query Neighborhood Hits	63	Target Neighborhood Hits	391	Shared Neighborhood Hits	27
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

SPTA1_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.153922 (rank : 38)
Query Neighborhood Hits	63	Target Neighborhood Hits	748	Shared Neighborhood Hits	39
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA1_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.158307 (rank : 34)
Query Neighborhood Hits	63	Target Neighborhood Hits	675	Shared Neighborhood Hits	35
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTN5_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.206147 (rank : 28)
Query Neighborhood Hits	63	Target Neighborhood Hits	674	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

SYNE2_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.147345 (rank : 41)
Query Neighborhood Hits	63	Target Neighborhood Hits	1323	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

UTRO_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.156646 (rank : 36)
Query Neighborhood Hits	63	Target Neighborhood Hits	960	Shared Neighborhood Hits	48
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

Hits sorted by NC score

PARVA_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	63	Target Neighborhood Hits	63	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NVD7, Q96C85, Q9HA48	Gene names	PARVA
Domain Architecture
Description	Alpha-parvin (Calponin-like integrin-linked kinase-binding protein) (CH-ILKBP).

PARVA_MOUSE
NC score	0.998814 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	63	Target Neighborhood Hits	61	Shared Neighborhood Hits	55
SwissProt Accessions	Q9EPC1, Q9JJ65	Gene names	Parva, Actp
Domain Architecture
Description	Alpha-parvin (Actopaxin).

PARVB_HUMAN
NC score	0.991366 (rank : 3)	θ value	1.98498e-148 (rank : 3)
Query Neighborhood Hits	63	Target Neighborhood Hits	42	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HBI1, Q5TGJ5, Q86X93, Q9NSP7, Q9UGT3, Q9Y368, Q9Y3L6, Q9Y3L7	Gene names	PARVB
Domain Architecture
Description	Beta-parvin (Affixin).

PARVB_MOUSE
NC score	0.990471 (rank : 4)	θ value	1.57279e-145 (rank : 4)
Query Neighborhood Hits	63	Target Neighborhood Hits	43	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ES46	Gene names	Parvb
Domain Architecture
Description	Beta-parvin.

PARVG_MOUSE
NC score	0.943989 (rank : 5)	θ value	1.45591e-66 (rank : 6)
Query Neighborhood Hits	63	Target Neighborhood Hits	41	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ERD8, Q91X89	Gene names	Parvg
Domain Architecture
Description	Gamma-parvin.

PARVG_HUMAN
NC score	0.935559 (rank : 6)	θ value	5.00389e-67 (rank : 5)
Query Neighborhood Hits	63	Target Neighborhood Hits	44	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HBI0, Q9BQX5, Q9NSG1	Gene names	PARVG
Domain Architecture
Description	Gamma-parvin.

ACTN4_HUMAN
NC score	0.322326 (rank : 7)	θ value	7.1131e-05 (rank : 11)
Query Neighborhood Hits	63	Target Neighborhood Hits	279	Shared Neighborhood Hits	44
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN4_MOUSE
NC score	0.322083 (rank : 8)	θ value	7.1131e-05 (rank : 12)
Query Neighborhood Hits	63	Target Neighborhood Hits	276	Shared Neighborhood Hits	42
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN1_MOUSE
NC score	0.319119 (rank : 9)	θ value	9.29e-05 (rank : 14)
Query Neighborhood Hits	63	Target Neighborhood Hits	216	Shared Neighborhood Hits	34
SwissProt Accessions	Q7TPR4	Gene names	Actn1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN1_HUMAN
NC score	0.318546 (rank : 10)	θ value	9.29e-05 (rank : 13)
Query Neighborhood Hits	63	Target Neighborhood Hits	221	Shared Neighborhood Hits	36
SwissProt Accessions	P12814, Q9BTN1	Gene names	ACTN1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN3_HUMAN
NC score	0.316117 (rank : 11)	θ value	4.92598e-06 (rank : 7)
Query Neighborhood Hits	63	Target Neighborhood Hits	272	Shared Neighborhood Hits	42
SwissProt Accessions	Q08043	Gene names	ACTN3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN3_MOUSE
NC score	0.315458 (rank : 12)	θ value	4.92598e-06 (rank : 8)
Query Neighborhood Hits	63	Target Neighborhood Hits	265	Shared Neighborhood Hits	46
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN2_HUMAN
NC score	0.311972 (rank : 13)	θ value	1.87187e-05 (rank : 9)
Query Neighborhood Hits	63	Target Neighborhood Hits	295	Shared Neighborhood Hits	45
SwissProt Accessions	P35609, Q86TF4, Q86TI8	Gene names	ACTN2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ACTN2_MOUSE
NC score	0.311926 (rank : 14)	θ value	1.87187e-05 (rank : 10)
Query Neighborhood Hits	63	Target Neighborhood Hits	287	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JI91	Gene names	Actn2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

FLNB_MOUSE
NC score	0.290903 (rank : 15)	θ value	0.000461057 (rank : 15)
Query Neighborhood Hits	63	Target Neighborhood Hits	126	Shared Neighborhood Hits	32
SwissProt Accessions	Q80X90, Q8VHX4, Q8VHX7, Q99KY3	Gene names	Flnb
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (ABP- 280-like protein).

FLNC_HUMAN
NC score	0.283671 (rank : 16)	θ value	0.00390308 (rank : 22)
Query Neighborhood Hits	63	Target Neighborhood Hits	116	Shared Neighborhood Hits	32
SwissProt Accessions	Q14315, O95303, Q07985, Q9NS12, Q9NYE5, Q9UMR8, Q9Y503	Gene names	FLNC, ABPL, FLN2
Domain Architecture
Description	Filamin-C (Gamma-filamin) (Filamin-2) (Protein FLNc) (Actin-binding- like protein) (ABP-L) (ABP-280-like protein).

FLNA_HUMAN
NC score	0.278019 (rank : 17)	θ value	0.0252991 (rank : 25)
Query Neighborhood Hits	63	Target Neighborhood Hits	138	Shared Neighborhood Hits	33
SwissProt Accessions	P21333	Gene names	FLNA, FLN, FLN1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

FLNA_MOUSE
NC score	0.277424 (rank : 18)	θ value	0.0252991 (rank : 26)
Query Neighborhood Hits	63	Target Neighborhood Hits	142	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BTM8, O54934, Q7TQI1, Q8BLK1, Q8BTN7, Q8VHX5, Q8VHX8, Q99KQ2	Gene names	Flna, Fln, Fln1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

FLNB_HUMAN
NC score	0.276089 (rank : 19)	θ value	0.0113563 (rank : 23)
Query Neighborhood Hits	63	Target Neighborhood Hits	111	Shared Neighborhood Hits	32
SwissProt Accessions	O75369, Q13706, Q8WXS9, Q8WXT0, Q8WXT1, Q8WXT2, Q9NRB5, Q9NT26, Q9UEV9	Gene names	FLNB, FLN1L, FLN3, TABP, TAP
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP) (ABP- 280 homolog) (ABP-278) (Filamin 3) (Filamin homolog 1) (Fh1).

CLMN_MOUSE
NC score	0.270514 (rank : 20)	θ value	0.0563607 (rank : 29)
Query Neighborhood Hits	63	Target Neighborhood Hits	180	Shared Neighborhood Hits	32
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

CLMN_HUMAN
NC score	0.261088 (rank : 21)	θ value	0.0736092 (rank : 30)
Query Neighborhood Hits	63	Target Neighborhood Hits	205	Shared Neighborhood Hits	31
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

SPTN4_HUMAN
NC score	0.250849 (rank : 22)	θ value	0.125558 (rank : 32)
Query Neighborhood Hits	63	Target Neighborhood Hits	570	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

SPTB1_HUMAN
NC score	0.246897 (rank : 23)	θ value	0.0148317 (rank : 24)
Query Neighborhood Hits	63	Target Neighborhood Hits	541	Shared Neighborhood Hits	48
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SPTN2_HUMAN
NC score	0.245211 (rank : 24)	θ value	0.0431538 (rank : 28)
Query Neighborhood Hits	63	Target Neighborhood Hits	535	Shared Neighborhood Hits	48
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

SPTB1_MOUSE
NC score	0.241604 (rank : 25)	θ value	0.0431538 (rank : 27)
Query Neighborhood Hits	63	Target Neighborhood Hits	543	Shared Neighborhood Hits	49
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SPTB2_HUMAN
NC score	0.238506 (rank : 26)	θ value	0.00175202 (rank : 19)
Query Neighborhood Hits	63	Target Neighborhood Hits	748	Shared Neighborhood Hits	51
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_MOUSE
NC score	0.237281 (rank : 27)	θ value	0.00175202 (rank : 20)
Query Neighborhood Hits	63	Target Neighborhood Hits	770	Shared Neighborhood Hits	51
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTN5_HUMAN
NC score	0.206147 (rank : 28)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	63	Target Neighborhood Hits	674	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

MACF1_MOUSE
NC score	0.205299 (rank : 29)	θ value	0.000786445 (rank : 17)
Query Neighborhood Hits	63	Target Neighborhood Hits	1313	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MACF1_HUMAN
NC score	0.198854 (rank : 30)	θ value	0.000786445 (rank : 16)
Query Neighborhood Hits	63	Target Neighborhood Hits	1341	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

BPA1_MOUSE
NC score	0.192351 (rank : 31)	θ value	0.00390308 (rank : 21)
Query Neighborhood Hits	63	Target Neighborhood Hits	1477	Shared Neighborhood Hits	54
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

PLEC1_HUMAN
NC score	0.178366 (rank : 32)	θ value	0.00134147 (rank : 18)
Query Neighborhood Hits	63	Target Neighborhood Hits	1326	Shared Neighborhood Hits	51
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

SMOO_HUMAN
NC score	0.162034 (rank : 33)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	63	Target Neighborhood Hits	391	Shared Neighborhood Hits	27
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

SPTA1_MOUSE
NC score	0.158307 (rank : 34)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	63	Target Neighborhood Hits	675	Shared Neighborhood Hits	35
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA2_HUMAN
NC score	0.157499 (rank : 35)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	63	Target Neighborhood Hits	888	Shared Neighborhood Hits	38
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

UTRO_HUMAN
NC score	0.156646 (rank : 36)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	63	Target Neighborhood Hits	960	Shared Neighborhood Hits	48
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

MILK2_HUMAN
NC score	0.154050 (rank : 37)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	63	Target Neighborhood Hits	457	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

SPTA1_HUMAN
NC score	0.153922 (rank : 38)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	63	Target Neighborhood Hits	748	Shared Neighborhood Hits	39
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

MILK1_HUMAN
NC score	0.151271 (rank : 39)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	63	Target Neighborhood Hits	427	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

DMD_HUMAN
NC score	0.150168 (rank : 40)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	63	Target Neighborhood Hits	1135	Shared Neighborhood Hits	51
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

SYNE2_HUMAN
NC score	0.147345 (rank : 41)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	63	Target Neighborhood Hits	1323	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

DMD_MOUSE
NC score	0.146960 (rank : 42)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	63	Target Neighborhood Hits	1111	Shared Neighborhood Hits	50
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

SYNE1_HUMAN
NC score	0.145763 (rank : 43)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	63	Target Neighborhood Hits	1484	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

MILK1_MOUSE
NC score	0.138695 (rank : 44)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	63	Target Neighborhood Hits	788	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MICA2_HUMAN
NC score	0.133189 (rank : 45)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	63	Target Neighborhood Hits	174	Shared Neighborhood Hits	28
SwissProt Accessions	O94851, Q7Z3A8	Gene names	MICAL2, KIAA0750
Domain Architecture
Description	Protein MICAL-2.

MICA3_MOUSE
NC score	0.126597 (rank : 46)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	63	Target Neighborhood Hits	104	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CJ19, Q80TE8, Q8BXB1	Gene names	Mical3, Kiaa1364
Domain Architecture
Description	Protein MICAL-3.

MICA3_HUMAN
NC score	0.122661 (rank : 47)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	63	Target Neighborhood Hits	160	Shared Neighborhood Hits	24
SwissProt Accessions	Q7RTP6, Q6ICK4, Q9P2I3	Gene names	MICAL3, KIAA1364
Domain Architecture
Description	Protein MICAL-3.

MICA2_MOUSE
NC score	0.117804 (rank : 48)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	63	Target Neighborhood Hits	144	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BML1, Q3UPU6	Gene names	Mical2
Domain Architecture
Description	Protein MICAL-2.

ASPM_MOUSE
NC score	0.114566 (rank : 49)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	63	Target Neighborhood Hits	150	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CJ27, O88482, Q8BJI8, Q8BKT4	Gene names	Aspm, Calmbp1, Sha1
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein homolog (Calmodulin-binding protein 1) (Spindle and hydroxyurea checkpoint abnormal protein) (Calmodulin-binding protein Sha1).

ASPM_HUMAN
NC score	0.113441 (rank : 50)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	63	Target Neighborhood Hits	197	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IZT6, Q86UX4, Q8IUL2, Q8IZJ7, Q8IZJ8, Q8IZJ9, Q8N4D1, Q9NVS1, Q9NVT6	Gene names	ASPM, MCPH5
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog).

MICA1_MOUSE
NC score	0.107741 (rank : 51)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	63	Target Neighborhood Hits	400	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

PLST_MOUSE
NC score	0.107083 (rank : 52)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	63	Target Neighborhood Hits	156	Shared Neighborhood Hits	27
SwissProt Accessions	Q99K51	Gene names	Pls3
Domain Architecture	No domain graphic available
Description	Plastin-3 (T-plastin).

PLST_HUMAN
NC score	0.106865 (rank : 53)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	63	Target Neighborhood Hits	161	Shared Neighborhood Hits	27
SwissProt Accessions	P13797, Q86YI6	Gene names	PLS3
Domain Architecture
Description	Plastin-3 (T-plastin).

PLSL_MOUSE
NC score	0.106385 (rank : 54)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	63	Target Neighborhood Hits	170	Shared Neighborhood Hits	28
SwissProt Accessions	Q61233, Q3UE24, Q8R1X3, Q9CV77	Gene names	Lcp1, Pls2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (pp65).

MICA1_HUMAN
NC score	0.105502 (rank : 55)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	63	Target Neighborhood Hits	279	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

BPAEA_HUMAN
NC score	0.104650 (rank : 56)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	63	Target Neighborhood Hits	1369	Shared Neighborhood Hits	40
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

PLSL_HUMAN
NC score	0.104128 (rank : 57)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	63	Target Neighborhood Hits	168	Shared Neighborhood Hits	28
SwissProt Accessions	P13796	Gene names	LCP1, PLS2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P).

MACF4_HUMAN
NC score	0.098884 (rank : 58)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	63	Target Neighborhood Hits	1321	Shared Neighborhood Hits	42
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

PLSI_HUMAN
NC score	0.095166 (rank : 59)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	63	Target Neighborhood Hits	209	Shared Neighborhood Hits	29
SwissProt Accessions	Q14651	Gene names	PLS1
Domain Architecture
Description	Plastin-1 (I-plastin) (Intestine-specific plastin).

CYTSA_HUMAN
NC score	0.094298 (rank : 60)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	63	Target Neighborhood Hits	1138	Shared Neighborhood Hits	47
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CYTSA_MOUSE
NC score	0.091994 (rank : 61)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	63	Target Neighborhood Hits	1104	Shared Neighborhood Hits	47
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

BPAEA_MOUSE
NC score	0.067055 (rank : 62)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	63	Target Neighborhood Hits	1480	Shared Neighborhood Hits	39
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MD1L1_MOUSE
NC score	0.063168 (rank : 63)	θ value	0.125558 (rank : 31)
Query Neighborhood Hits	63	Target Neighborhood Hits	1001	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

MD1L1_HUMAN
NC score	0.059618 (rank : 64)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	63	Target Neighborhood Hits	893	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

HAPIP_HUMAN
NC score	0.056770 (rank : 65)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	63	Target Neighborhood Hits	350	Shared Neighborhood Hits	30
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

DESP_HUMAN
NC score	0.053417 (rank : 66)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	63	Target Neighborhood Hits	1470	Shared Neighborhood Hits	40
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

PEPL_MOUSE
NC score	0.051303 (rank : 67)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	63	Target Neighborhood Hits	1105	Shared Neighborhood Hits	38
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

RABE1_HUMAN
NC score	0.051248 (rank : 68)	θ value	0.365318 (rank : 34)
Query Neighborhood Hits	63	Target Neighborhood Hits	1104	Shared Neighborhood Hits	35
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE1_MOUSE
NC score	0.050876 (rank : 69)	θ value	0.365318 (rank : 35)
Query Neighborhood Hits	63	Target Neighborhood Hits	1105	Shared Neighborhood Hits	36
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

PEPL_HUMAN
NC score	0.050540 (rank : 70)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	63	Target Neighborhood Hits	1141	Shared Neighborhood Hits	37
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

DYNA_HUMAN
NC score	0.048985 (rank : 71)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	63	Target Neighborhood Hits	1194	Shared Neighborhood Hits	41
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

DYNA_MOUSE
NC score	0.047487 (rank : 72)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	63	Target Neighborhood Hits	1084	Shared Neighborhood Hits	40
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

GCC1_MOUSE
NC score	0.046697 (rank : 73)	θ value	0.279714 (rank : 33)
Query Neighborhood Hits	63	Target Neighborhood Hits	777	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

MYH1_MOUSE
NC score	0.041963 (rank : 74)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	63	Target Neighborhood Hits	1461	Shared Neighborhood Hits	44
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH2_HUMAN
NC score	0.041784 (rank : 75)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	63	Target Neighborhood Hits	1491	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

NIN_MOUSE
NC score	0.041504 (rank : 76)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	63	Target Neighborhood Hits	1376	Shared Neighborhood Hits	37
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

MYH8_HUMAN
NC score	0.039757 (rank : 77)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	63	Target Neighborhood Hits	1610	Shared Neighborhood Hits	42
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH1_HUMAN
NC score	0.039712 (rank : 78)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	63	Target Neighborhood Hits	1478	Shared Neighborhood Hits	41
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

NUCB2_MOUSE
NC score	0.037022 (rank : 79)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	63	Target Neighborhood Hits	459	Shared Neighborhood Hits	20
SwissProt Accessions	P81117	Gene names	Nucb2, Nefa
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA).

MY18B_HUMAN
NC score	0.035667 (rank : 80)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	63	Target Neighborhood Hits	1299	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

GCC1_HUMAN
NC score	0.035175 (rank : 81)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	63	Target Neighborhood Hits	887	Shared Neighborhood Hits	29
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

DYH11_HUMAN
NC score	0.032407 (rank : 82)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	63	Target Neighborhood Hits	234	Shared Neighborhood Hits	16
SwissProt Accessions	Q96DT5, Q9UJ82	Gene names	DNAH11
Domain Architecture
Description	Ciliary dynein heavy chain 11 (Axonemal beta dynein heavy chain 11).

SMC1A_HUMAN
NC score	0.031913 (rank : 83)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	63	Target Neighborhood Hits	1346	Shared Neighborhood Hits	36
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

K0562_HUMAN
NC score	0.027214 (rank : 84)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	63	Target Neighborhood Hits	146	Shared Neighborhood Hits	8
SwissProt Accessions	O60308, Q5JSQ3, Q5SR24, Q5SR25, Q6PKF5, Q86W32, Q86X14	Gene names	KIAA0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

EVI2B_HUMAN
NC score	0.022315 (rank : 85)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	63	Target Neighborhood Hits	135	Shared Neighborhood Hits	3
SwissProt Accessions	P34910	Gene names	EVI2B, EVDB
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

KIF3B_HUMAN
NC score	0.017920 (rank : 86)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	63	Target Neighborhood Hits	540	Shared Neighborhood Hits	29
SwissProt Accessions	O15066	Gene names	KIF3B, KIAA0359
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048).

HAX1_HUMAN
NC score	0.017882 (rank : 87)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	63	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	O00165, Q96AU4, Q9BS80	Gene names	HAX1, HS1BP1
Domain Architecture	No domain graphic available
Description	HS1-associating protein X-1 (HAX-1) (HS1-binding protein).

KIF3B_MOUSE
NC score	0.017601 (rank : 88)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	63	Target Neighborhood Hits	533	Shared Neighborhood Hits	28
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

NBR1_MOUSE
NC score	0.013346 (rank : 89)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	63	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	P97432, Q9JIH9	Gene names	Nbr1, M17s2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2).

TP53B_HUMAN
NC score	0.011671 (rank : 90)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	63	Target Neighborhood Hits	413	Shared Neighborhood Hits	7
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

VASP_MOUSE
NC score	0.006503 (rank : 91)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	63	Target Neighborhood Hits	195	Shared Neighborhood Hits	3
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

BMP6_HUMAN
NC score	0.003560 (rank : 92)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	63	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	P22004	Gene names	BMP6, VGR
Domain Architecture
Description	Bone morphogenetic protein 6 precursor (BMP-6).

PRS6A_HUMAN
NC score	0.002750 (rank : 93)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	63	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	P17980, Q96HD3	Gene names	PSMC3, TBP1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1) (Proteasome subunit P50).

PTN21_MOUSE
NC score	0.001888 (rank : 94)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	63	Target Neighborhood Hits	155	Shared Neighborhood Hits	3
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).