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Network neighborhood for query Sequence : MUG1_MOUSE

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MUG1_MOUSE
SwissProt Accessions	P28665	Gene names	Mug1, Mug-1
Domain Architecture
Description	Murinoglobulin-1 precursor (MuG1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

A2MG_HUMAN
θ value	0 (rank : 1)	NC score	0.992476 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	32	Shared Neighborhood Hits	15
SwissProt Accessions	P01023, Q13677, Q59F47, Q5QTS0, Q68DN2, Q6PIY3, Q6PN97	Gene names	A2M
Domain Architecture
Description	Alpha-2-macroglobulin precursor (Alpha-2-M).

A2MG_MOUSE
θ value	0 (rank : 2)	NC score	0.989351 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	33	Shared Neighborhood Hits	12
SwissProt Accessions	Q61838, Q60628	Gene names	A2m
Domain Architecture
Description	Alpha-2-macroglobulin precursor (Alpha-2-M) [Contains: Alpha-2- macroglobulin 165 kDa subunit; Alpha-2-macroglobulin 35 kDa subunit].

MUG1_MOUSE
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	P28665	Gene names	Mug1, Mug-1
Domain Architecture
Description	Murinoglobulin-1 precursor (MuG1).

MUG2_MOUSE
θ value	0 (rank : 4)	NC score	0.996540 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	P28666	Gene names	Mug2, Mug-2
Domain Architecture
Description	Murinoglobulin-2 precursor (MuG2).

PZP_HUMAN
θ value	0 (rank : 5)	NC score	0.992018 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	P20742, Q15273	Gene names	PZP
Domain Architecture
Description	Pregnancy zone protein precursor.

CO5_MOUSE
θ value	1.31376e-75 (rank : 6)	NC score	0.830264 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	23	Shared Neighborhood Hits	12
SwissProt Accessions	P06684	Gene names	C5, Hc
Domain Architecture
Description	Complement C5 precursor (Hemolytic complement) [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

CO4B_MOUSE
θ value	1.31681e-67 (rank : 7)	NC score	0.803703 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	P01029, Q31201, Q61372, Q61859, Q62353	Gene names	C4b, C4
Domain Architecture
Description	Complement C4-B precursor [Contains: Complement C4 beta chain; Complement C4 alpha chain; C4a anaphylatoxin; Complement C4 gamma chain].

CO5_HUMAN
θ value	2.24614e-67 (rank : 8)	NC score	0.816871 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	P01031	Gene names	C5
Domain Architecture
Description	Complement C5 precursor [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

CO3_MOUSE
θ value	3.1488e-53 (rank : 9)	NC score	0.806187 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	33	Shared Neighborhood Hits	12
SwissProt Accessions	P01027, Q61370	Gene names	C3
Domain Architecture
Description	Complement C3 precursor (HSE-MSF) [Contains: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3c fragment; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3, isoform Short; Complement C3f fragment].

CO3_HUMAN
θ value	9.16162e-53 (rank : 10)	NC score	0.802644 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	P01024	Gene names	C3
Domain Architecture
Description	Complement C3 precursor [Contains: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3c fragment; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment].

CO4B_HUMAN
θ value	2.3352e-48 (rank : 11)	NC score	0.793185 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	P0C0L5, P01028, P78445, Q13160, Q13906, Q14033, Q14835, Q9NPK5, Q9UIP5	Gene names	C4B
Domain Architecture	No domain graphic available
Description	Complement C4-B precursor (Basic complement C4) [Contains: Complement C4 beta chain; Complement C4-B alpha chain; C4a anaphylatoxin; C4b-B; C4d-B; Complement C4 gamma chain].

CO4A_HUMAN
θ value	3.98324e-48 (rank : 12)	NC score	0.792951 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	P0C0L4, P01028, P78445, Q13160, Q13906, Q14033, Q14835, Q5JQM8, Q9NPK5, Q9UIP5	Gene names	C4A
Domain Architecture	No domain graphic available
Description	Complement C4-A precursor (Acidic complement C4) [Contains: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain].

CELR2_MOUSE
θ value	0.0193708 (rank : 13)	NC score	0.012342 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	584	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CELR2_HUMAN
θ value	0.163984 (rank : 14)	NC score	0.009442 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	657	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

ROCK2_HUMAN
θ value	0.47712 (rank : 15)	NC score	0.000314 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	2073	Shared Neighborhood Hits	9
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

MPRI_MOUSE
θ value	0.813845 (rank : 16)	NC score	0.018621 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q07113, Q61822, Q6LED1	Gene names	Igf2r
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300).

PLEC1_HUMAN
θ value	1.38821 (rank : 17)	NC score	0.003029 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	1326	Shared Neighborhood Hits	7
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

5NT1B_HUMAN
θ value	1.81305 (rank : 18)	NC score	0.016896 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q96P26, Q8N9W3, Q8NA26, Q96DU5, Q96KE6, Q96M25, Q96SA3	Gene names	NT5C1B, AIRP
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

CASC5_HUMAN
θ value	2.36792 (rank : 19)	NC score	0.013199 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	376	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

RRP5_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.020420 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	291	Shared Neighborhood Hits	5
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

DPOD3_MOUSE
θ value	3.0926 (rank : 21)	NC score	0.016117 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	118	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQ28	Gene names	Pold3
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

ITA5_MOUSE
θ value	3.0926 (rank : 22)	NC score	0.012350 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	P11688	Gene names	Itga5
Domain Architecture
Description	Integrin alpha-5 precursor (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD49e antigen) [Contains: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain].

ANLN_HUMAN
θ value	4.03905 (rank : 23)	NC score	0.010922 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	222	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

MYO5C_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.001414 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	1206	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

POLK_HUMAN
θ value	4.03905 (rank : 25)	NC score	0.011273 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBT6, Q86VJ8, Q8IZY0, Q8IZY1, Q8NB30, Q96L01, Q96Q86, Q96Q87, Q9UHC5	Gene names	POLK, DINB1
Domain Architecture	No domain graphic available
Description	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP).

CLIC5_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.006497 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZA1, Q5T4Z0, Q96JT5, Q9BWZ0	Gene names	CLIC5
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel protein 5.

ITA5_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.010458 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	P08648, Q96HA5	Gene names	ITGA5, FNRA
Domain Architecture
Description	Integrin alpha-5 precursor (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD49e antigen) [Contains: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain].

SRTD2_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.012317 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	Q14140	Gene names	SERTAD2, KIAA0127
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

CGAT1_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.006328 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TDX6, Q6P9G6, Q8IUF9, Q9NSQ7, Q9NUM9	Gene names	GALNACT1, CHGN
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.174) (beta4GalNAcT-1).

FBXL6_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.008726 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXW0, Q9JJD7	Gene names	Fbxl6, Fbl6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6).

RPGR1_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.005438 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	578	Shared Neighborhood Hits	5
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SP4_HUMAN
θ value	6.88961 (rank : 32)	NC score	-0.001392 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	749	Shared Neighborhood Hits	3
SwissProt Accessions	Q02446, O60402	Gene names	SP4
Domain Architecture
Description	Transcription factor Sp4 (SPR-1).

SRF_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.009657 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	P11831	Gene names	SRF
Domain Architecture
Description	Serum response factor (SRF).

ZEP1_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.002022 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	1036	Shared Neighborhood Hits	6
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

ZRAN1_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.014572 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGI0	Gene names	ZRANB1, TRABID
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 1 (Protein TRABID).

DPOLQ_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.008440 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	O75417, O95160	Gene names	POLQ, POLH
Domain Architecture
Description	DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta).

IF4B_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.008668 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	368	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

NEK4_HUMAN
θ value	8.99809 (rank : 38)	NC score	-0.001818 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	883	Shared Neighborhood Hits	3
SwissProt Accessions	P51957	Gene names	NEK4, STK2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2).

SOS1_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.005311 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	274	Shared Neighborhood Hits	3
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SOS1_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.005273 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	281	Shared Neighborhood Hits	3
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

Hits sorted by NC score

MUG1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	P28665	Gene names	Mug1, Mug-1
Domain Architecture
Description	Murinoglobulin-1 precursor (MuG1).

MUG2_MOUSE
NC score	0.996540 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	P28666	Gene names	Mug2, Mug-2
Domain Architecture
Description	Murinoglobulin-2 precursor (MuG2).

A2MG_HUMAN
NC score	0.992476 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	32	Shared Neighborhood Hits	15
SwissProt Accessions	P01023, Q13677, Q59F47, Q5QTS0, Q68DN2, Q6PIY3, Q6PN97	Gene names	A2M
Domain Architecture
Description	Alpha-2-macroglobulin precursor (Alpha-2-M).

PZP_HUMAN
NC score	0.992018 (rank : 4)	θ value	0 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	P20742, Q15273	Gene names	PZP
Domain Architecture
Description	Pregnancy zone protein precursor.

A2MG_MOUSE
NC score	0.989351 (rank : 5)	θ value	0 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	33	Shared Neighborhood Hits	12
SwissProt Accessions	Q61838, Q60628	Gene names	A2m
Domain Architecture
Description	Alpha-2-macroglobulin precursor (Alpha-2-M) [Contains: Alpha-2- macroglobulin 165 kDa subunit; Alpha-2-macroglobulin 35 kDa subunit].

CO5_MOUSE
NC score	0.830264 (rank : 6)	θ value	1.31376e-75 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	23	Shared Neighborhood Hits	12
SwissProt Accessions	P06684	Gene names	C5, Hc
Domain Architecture
Description	Complement C5 precursor (Hemolytic complement) [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

CO5_HUMAN
NC score	0.816871 (rank : 7)	θ value	2.24614e-67 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	P01031	Gene names	C5
Domain Architecture
Description	Complement C5 precursor [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

CO3_MOUSE
NC score	0.806187 (rank : 8)	θ value	3.1488e-53 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	33	Shared Neighborhood Hits	12
SwissProt Accessions	P01027, Q61370	Gene names	C3
Domain Architecture
Description	Complement C3 precursor (HSE-MSF) [Contains: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3c fragment; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3, isoform Short; Complement C3f fragment].

CO4B_MOUSE
NC score	0.803703 (rank : 9)	θ value	1.31681e-67 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	P01029, Q31201, Q61372, Q61859, Q62353	Gene names	C4b, C4
Domain Architecture
Description	Complement C4-B precursor [Contains: Complement C4 beta chain; Complement C4 alpha chain; C4a anaphylatoxin; Complement C4 gamma chain].

CO3_HUMAN
NC score	0.802644 (rank : 10)	θ value	9.16162e-53 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	P01024	Gene names	C3
Domain Architecture
Description	Complement C3 precursor [Contains: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3c fragment; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment].

CO4B_HUMAN
NC score	0.793185 (rank : 11)	θ value	2.3352e-48 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	P0C0L5, P01028, P78445, Q13160, Q13906, Q14033, Q14835, Q9NPK5, Q9UIP5	Gene names	C4B
Domain Architecture	No domain graphic available
Description	Complement C4-B precursor (Basic complement C4) [Contains: Complement C4 beta chain; Complement C4-B alpha chain; C4a anaphylatoxin; C4b-B; C4d-B; Complement C4 gamma chain].

CO4A_HUMAN
NC score	0.792951 (rank : 12)	θ value	3.98324e-48 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	P0C0L4, P01028, P78445, Q13160, Q13906, Q14033, Q14835, Q5JQM8, Q9NPK5, Q9UIP5	Gene names	C4A
Domain Architecture	No domain graphic available
Description	Complement C4-A precursor (Acidic complement C4) [Contains: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain].

RRP5_HUMAN
NC score	0.020420 (rank : 13)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	291	Shared Neighborhood Hits	5
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

MPRI_MOUSE
NC score	0.018621 (rank : 14)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q07113, Q61822, Q6LED1	Gene names	Igf2r
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300).

5NT1B_HUMAN
NC score	0.016896 (rank : 15)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q96P26, Q8N9W3, Q8NA26, Q96DU5, Q96KE6, Q96M25, Q96SA3	Gene names	NT5C1B, AIRP
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

DPOD3_MOUSE
NC score	0.016117 (rank : 16)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	118	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQ28	Gene names	Pold3
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

ZRAN1_HUMAN
NC score	0.014572 (rank : 17)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGI0	Gene names	ZRANB1, TRABID
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 1 (Protein TRABID).

CASC5_HUMAN
NC score	0.013199 (rank : 18)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	376	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

ITA5_MOUSE
NC score	0.012350 (rank : 19)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	P11688	Gene names	Itga5
Domain Architecture
Description	Integrin alpha-5 precursor (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD49e antigen) [Contains: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain].

CELR2_MOUSE
NC score	0.012342 (rank : 20)	θ value	0.0193708 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	584	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

SRTD2_HUMAN
NC score	0.012317 (rank : 21)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	Q14140	Gene names	SERTAD2, KIAA0127
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

POLK_HUMAN
NC score	0.011273 (rank : 22)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBT6, Q86VJ8, Q8IZY0, Q8IZY1, Q8NB30, Q96L01, Q96Q86, Q96Q87, Q9UHC5	Gene names	POLK, DINB1
Domain Architecture	No domain graphic available
Description	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP).

ANLN_HUMAN
NC score	0.010922 (rank : 23)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	222	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

ITA5_HUMAN
NC score	0.010458 (rank : 24)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	P08648, Q96HA5	Gene names	ITGA5, FNRA
Domain Architecture
Description	Integrin alpha-5 precursor (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD49e antigen) [Contains: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain].

SRF_HUMAN
NC score	0.009657 (rank : 25)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	P11831	Gene names	SRF
Domain Architecture
Description	Serum response factor (SRF).

CELR2_HUMAN
NC score	0.009442 (rank : 26)	θ value	0.163984 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	657	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

FBXL6_MOUSE
NC score	0.008726 (rank : 27)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXW0, Q9JJD7	Gene names	Fbxl6, Fbl6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6).

IF4B_MOUSE
NC score	0.008668 (rank : 28)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	368	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

DPOLQ_HUMAN
NC score	0.008440 (rank : 29)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	O75417, O95160	Gene names	POLQ, POLH
Domain Architecture
Description	DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta).

CLIC5_HUMAN
NC score	0.006497 (rank : 30)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZA1, Q5T4Z0, Q96JT5, Q9BWZ0	Gene names	CLIC5
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel protein 5.

CGAT1_HUMAN
NC score	0.006328 (rank : 31)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TDX6, Q6P9G6, Q8IUF9, Q9NSQ7, Q9NUM9	Gene names	GALNACT1, CHGN
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.174) (beta4GalNAcT-1).

RPGR1_HUMAN
NC score	0.005438 (rank : 32)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	578	Shared Neighborhood Hits	5
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SOS1_HUMAN
NC score	0.005311 (rank : 33)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	274	Shared Neighborhood Hits	3
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SOS1_MOUSE
NC score	0.005273 (rank : 34)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	281	Shared Neighborhood Hits	3
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

PLEC1_HUMAN
NC score	0.003029 (rank : 35)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	1326	Shared Neighborhood Hits	7
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

ZEP1_HUMAN
NC score	0.002022 (rank : 36)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	1036	Shared Neighborhood Hits	6
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

MYO5C_HUMAN
NC score	0.001414 (rank : 37)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	1206	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

ROCK2_HUMAN
NC score	0.000314 (rank : 38)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	2073	Shared Neighborhood Hits	9
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

SP4_HUMAN
NC score	-0.001392 (rank : 39)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	749	Shared Neighborhood Hits	3
SwissProt Accessions	Q02446, O60402	Gene names	SP4
Domain Architecture
Description	Transcription factor Sp4 (SPR-1).

NEK4_HUMAN
NC score	-0.001818 (rank : 40)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	883	Shared Neighborhood Hits	3
SwissProt Accessions	P51957	Gene names	NEK4, STK2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2).