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Network neighborhood for query Sequence : TXND9_HUMAN

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TXND9_HUMAN
SwissProt Accessions	O14530, Q53RV8, Q6NSF5, Q9BRU6	Gene names	TXNDC9, APACD
Domain Architecture
Description	Thioredoxin domain-containing protein 9 (Protein 1-4) (ATP-binding protein associated with cell differentiation).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TXND9_HUMAN
θ value	1.75513e-112 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	31
SwissProt Accessions	O14530, Q53RV8, Q6NSF5, Q9BRU6	Gene names	TXNDC9, APACD
Domain Architecture
Description	Thioredoxin domain-containing protein 9 (Protein 1-4) (ATP-binding protein associated with cell differentiation).

TXND9_MOUSE
θ value	2.54029e-103 (rank : 2)	NC score	0.992714 (rank : 2)
Query Neighborhood Hits	31	Target Neighborhood Hits	23	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CQ79, Q3TKD2	Gene names	Txndc9, Apacd
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 9 (ATP-binding protein associated with cell differentiation).

PDCL2_MOUSE
θ value	1.33837e-11 (rank : 3)	NC score	0.570045 (rank : 3)
Query Neighborhood Hits	31	Target Neighborhood Hits	32	Shared Neighborhood Hits	13
SwissProt Accessions	Q78Y63	Gene names	Pdcl2
Domain Architecture	No domain graphic available
Description	Phosducin-like protein 2.

PDCL2_HUMAN
θ value	3.29651e-10 (rank : 4)	NC score	0.547257 (rank : 4)
Query Neighborhood Hits	31	Target Neighborhood Hits	49	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N4E4	Gene names	PDCL2
Domain Architecture	No domain graphic available
Description	Phosducin-like protein 2.

PDCL3_MOUSE
θ value	4.45536e-07 (rank : 5)	NC score	0.512700 (rank : 5)
Query Neighborhood Hits	31	Target Neighborhood Hits	45	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BVF2, Q3TH06, Q99JX2, Q9D0W3	Gene names	Pdcl3, Viaf1
Domain Architecture	No domain graphic available
Description	Phosducin-like protein 3 (Viral IAP-associated factor 1) (VIAF-1).

PDCL3_HUMAN
θ value	8.40245e-06 (rank : 6)	NC score	0.490948 (rank : 6)
Query Neighborhood Hits	31	Target Neighborhood Hits	33	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H2J4	Gene names	PDCL3, VIAF1
Domain Architecture	No domain graphic available
Description	Phosducin-like protein 3 (Viral IAP-associated factor 1) (VIAF-1) (HTPHLP).

TXNL2_MOUSE
θ value	0.00298849 (rank : 7)	NC score	0.255300 (rank : 9)
Query Neighborhood Hits	31	Target Neighborhood Hits	54	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CQM9, Q9JLZ2	Gene names	Txnl2, Picot
Domain Architecture
Description	Thioredoxin-like protein 2 (PKC-interacting cousin of thioredoxin) (PKC-theta-interacting protein) (PKCq-interacting protein).

PHOS_HUMAN
θ value	0.0252991 (rank : 8)	NC score	0.277778 (rank : 7)
Query Neighborhood Hits	31	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	P20941, Q14816	Gene names	PDC
Domain Architecture
Description	Phosducin (PHD) (33 kDa phototransducing protein) (MEKA protein).

PHOS_MOUSE
θ value	0.0330416 (rank : 9)	NC score	0.269814 (rank : 8)
Query Neighborhood Hits	31	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QW08	Gene names	Pdc, Rpr1
Domain Architecture
Description	Phosducin (PHD) (33 kDa phototransducing protein) (Rod photoreceptor 1) (RPR-1).

THIOM_HUMAN
θ value	0.0431538 (rank : 10)	NC score	0.187756 (rank : 14)
Query Neighborhood Hits	31	Target Neighborhood Hits	46	Shared Neighborhood Hits	15
SwissProt Accessions	Q99757, Q5JZA0, Q9UH29	Gene names	TXN2, TRX2
Domain Architecture
Description	Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2).

THIOM_MOUSE
θ value	0.0431538 (rank : 11)	NC score	0.188190 (rank : 13)
Query Neighborhood Hits	31	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	P97493, Q545D5	Gene names	Txn2
Domain Architecture
Description	Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2).

TXNL2_HUMAN
θ value	0.0431538 (rank : 12)	NC score	0.226620 (rank : 10)
Query Neighborhood Hits	31	Target Neighborhood Hits	59	Shared Neighborhood Hits	17
SwissProt Accessions	O76003, Q96CE0, Q9P1B0, Q9P1B1	Gene names	TXNL2, PICOT
Domain Architecture
Description	Thioredoxin-like protein 2 (PKC-interacting cousin of thioredoxin) (PKC-theta-interacting protein) (PKCq-interacting protein).

UTRO_HUMAN
θ value	0.279714 (rank : 13)	NC score	0.033887 (rank : 28)
Query Neighborhood Hits	31	Target Neighborhood Hits	960	Shared Neighborhood Hits	11
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

HSP74_MOUSE
θ value	0.813845 (rank : 14)	NC score	0.020991 (rank : 32)
Query Neighborhood Hits	31	Target Neighborhood Hits	257	Shared Neighborhood Hits	5
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

PDIA4_HUMAN
θ value	0.813845 (rank : 15)	NC score	0.065766 (rank : 20)
Query Neighborhood Hits	31	Target Neighborhood Hits	60	Shared Neighborhood Hits	12
SwissProt Accessions	P13667	Gene names	PDIA4, ERP70, ERP72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

TXND2_HUMAN
θ value	1.06291 (rank : 16)	NC score	0.047814 (rank : 27)
Query Neighborhood Hits	31	Target Neighborhood Hits	793	Shared Neighborhood Hits	13
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

GOGB1_HUMAN
θ value	1.81305 (rank : 17)	NC score	0.018227 (rank : 33)
Query Neighborhood Hits	31	Target Neighborhood Hits	2297	Shared Neighborhood Hits	13
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

NIN_HUMAN
θ value	1.81305 (rank : 18)	NC score	0.023031 (rank : 30)
Query Neighborhood Hits	31	Target Neighborhood Hits	1416	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

RUFY2_MOUSE
θ value	1.81305 (rank : 19)	NC score	0.021470 (rank : 31)
Query Neighborhood Hits	31	Target Neighborhood Hits	820	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

CCD46_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.017731 (rank : 34)
Query Neighborhood Hits	31	Target Neighborhood Hits	1430	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

TXND8_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.086894 (rank : 17)
Query Neighborhood Hits	31	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	Q6A555, Q5T934	Gene names	TXNDC8, SPTRX3, TRX6
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 8 (Spermatid-specific thioredoxin-3) (Sptrx-3) (Thioredoxin-6).

SLK_HUMAN
θ value	3.0926 (rank : 22)	NC score	0.009643 (rank : 38)
Query Neighborhood Hits	31	Target Neighborhood Hits	1775	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

SLK_MOUSE
θ value	3.0926 (rank : 23)	NC score	0.008934 (rank : 40)
Query Neighborhood Hits	31	Target Neighborhood Hits	1798	Shared Neighborhood Hits	11
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

STXB4_HUMAN
θ value	3.0926 (rank : 24)	NC score	0.031499 (rank : 29)
Query Neighborhood Hits	31	Target Neighborhood Hits	616	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

STK10_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.010737 (rank : 37)
Query Neighborhood Hits	31	Target Neighborhood Hits	2132	Shared Neighborhood Hits	15
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TXND5_MOUSE
θ value	5.27518 (rank : 26)	NC score	0.067933 (rank : 19)
Query Neighborhood Hits	31	Target Neighborhood Hits	52	Shared Neighborhood Hits	12
SwissProt Accessions	Q91W90, Q8R1I6	Gene names	Txndc5, Tlp46
Domain Architecture
Description	Thioredoxin domain-containing protein 5 precursor (Thioredoxin-like protein p46) (Endoplasmic reticulum protein ERp46) (Plasma cell- specific thioredoxin-related protein) (PC-TRP).

DMXL2_HUMAN
θ value	6.88961 (rank : 27)	NC score	0.012115 (rank : 36)
Query Neighborhood Hits	31	Target Neighborhood Hits	374	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

PDIA5_HUMAN
θ value	6.88961 (rank : 28)	NC score	0.052545 (rank : 24)
Query Neighborhood Hits	31	Target Neighborhood Hits	42	Shared Neighborhood Hits	11
SwissProt Accessions	Q14554	Gene names	PDIA5, PDIR
Domain Architecture
Description	Protein disulfide-isomerase A5 precursor (EC 5.3.4.1) (Protein disulfide isomerase-related protein).

ITSN1_MOUSE
θ value	8.99809 (rank : 29)	NC score	0.008992 (rank : 39)
Query Neighborhood Hits	31	Target Neighborhood Hits	1669	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

PRC1_HUMAN
θ value	8.99809 (rank : 30)	NC score	0.016737 (rank : 35)
Query Neighborhood Hits	31	Target Neighborhood Hits	328	Shared Neighborhood Hits	8
SwissProt Accessions	O43663, Q9BSB6	Gene names	PRC1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

THIO_HUMAN
θ value	8.99809 (rank : 31)	NC score	0.100726 (rank : 15)
Query Neighborhood Hits	31	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	P10599, Q96KI3	Gene names	TXN, TRDX, TRX, TRX1
Domain Architecture
Description	Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP).

GLRX5_HUMAN
θ value	θ > 10 (rank : 32)	NC score	0.060396 (rank : 21)
Query Neighborhood Hits	31	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q86SX6, Q3YML0, Q86WY3, Q8IZ54	Gene names	GLRX5, C14orf87
Domain Architecture	No domain graphic available
Description	Glutaredoxin-related protein 5.

GLRX5_MOUSE
θ value	θ > 10 (rank : 33)	NC score	0.060306 (rank : 22)
Query Neighborhood Hits	31	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q80Y14, Q3YML1, Q9D6E9	Gene names	Glrx5
Domain Architecture	No domain graphic available
Description	Glutaredoxin-related protein 5.

PHLP_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.198911 (rank : 11)
Query Neighborhood Hits	31	Target Neighborhood Hits	28	Shared Neighborhood Hits	9
SwissProt Accessions	Q13371, Q96AF1, Q9UEW7, Q9UFL0	Gene names	PDCL
Domain Architecture
Description	Phosducin-like protein (PHLP).

PHLP_MOUSE
θ value	θ > 10 (rank : 35)	NC score	0.191939 (rank : 12)
Query Neighborhood Hits	31	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DBX2, Q3TKI0	Gene names	Pdcl
Domain Architecture
Description	Phosducin-like protein (PHLP).

THIO_MOUSE
θ value	θ > 10 (rank : 36)	NC score	0.092604 (rank : 16)
Query Neighborhood Hits	31	Target Neighborhood Hits	39	Shared Neighborhood Hits	12
SwissProt Accessions	P10639, Q52KC4, Q9D8R0	Gene names	Txn, Txn1
Domain Architecture
Description	Thioredoxin (Trx) (ATL-derived factor) (ADF).

TXND5_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.053277 (rank : 23)
Query Neighborhood Hits	31	Target Neighborhood Hits	54	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NBS9, Q8ND33, Q8TCT2, Q9BVH9	Gene names	TXNDC5, TLP46
Domain Architecture
Description	Thioredoxin domain-containing protein 5 precursor (Thioredoxin-like protein p46) (Endoplasmic reticulum protein ERp46).

TXND8_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.072650 (rank : 18)
Query Neighborhood Hits	31	Target Neighborhood Hits	41	Shared Neighborhood Hits	10
SwissProt Accessions	Q69AB2, Q78Y03, Q80YE0, Q9CQ96	Gene names	Txndc8, Sptrx3, Trx6
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 8 (Spermatid-specific thioredoxin-3) (Sptrx-3) (Thioredoxin-6).

TXNL1_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.051531 (rank : 26)
Query Neighborhood Hits	31	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	O43396	Gene names	TXNL1, TRP32, TXL, TXNL
Domain Architecture
Description	Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein).

TXNL1_MOUSE
θ value	θ > 10 (rank : 40)	NC score	0.051568 (rank : 25)
Query Neighborhood Hits	31	Target Neighborhood Hits	29	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CDN6, O70379, Q3TI92	Gene names	Txnl1, Trp32, Txnl
Domain Architecture	No domain graphic available
Description	Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein).

Hits sorted by NC score

TXND9_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.75513e-112 (rank : 1)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	31
SwissProt Accessions	O14530, Q53RV8, Q6NSF5, Q9BRU6	Gene names	TXNDC9, APACD
Domain Architecture
Description	Thioredoxin domain-containing protein 9 (Protein 1-4) (ATP-binding protein associated with cell differentiation).

TXND9_MOUSE
NC score	0.992714 (rank : 2)	θ value	2.54029e-103 (rank : 2)
Query Neighborhood Hits	31	Target Neighborhood Hits	23	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CQ79, Q3TKD2	Gene names	Txndc9, Apacd
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 9 (ATP-binding protein associated with cell differentiation).

PDCL2_MOUSE
NC score	0.570045 (rank : 3)	θ value	1.33837e-11 (rank : 3)
Query Neighborhood Hits	31	Target Neighborhood Hits	32	Shared Neighborhood Hits	13
SwissProt Accessions	Q78Y63	Gene names	Pdcl2
Domain Architecture	No domain graphic available
Description	Phosducin-like protein 2.

PDCL2_HUMAN
NC score	0.547257 (rank : 4)	θ value	3.29651e-10 (rank : 4)
Query Neighborhood Hits	31	Target Neighborhood Hits	49	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N4E4	Gene names	PDCL2
Domain Architecture	No domain graphic available
Description	Phosducin-like protein 2.

PDCL3_MOUSE
NC score	0.512700 (rank : 5)	θ value	4.45536e-07 (rank : 5)
Query Neighborhood Hits	31	Target Neighborhood Hits	45	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BVF2, Q3TH06, Q99JX2, Q9D0W3	Gene names	Pdcl3, Viaf1
Domain Architecture	No domain graphic available
Description	Phosducin-like protein 3 (Viral IAP-associated factor 1) (VIAF-1).

PDCL3_HUMAN
NC score	0.490948 (rank : 6)	θ value	8.40245e-06 (rank : 6)
Query Neighborhood Hits	31	Target Neighborhood Hits	33	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H2J4	Gene names	PDCL3, VIAF1
Domain Architecture	No domain graphic available
Description	Phosducin-like protein 3 (Viral IAP-associated factor 1) (VIAF-1) (HTPHLP).

PHOS_HUMAN
NC score	0.277778 (rank : 7)	θ value	0.0252991 (rank : 8)
Query Neighborhood Hits	31	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	P20941, Q14816	Gene names	PDC
Domain Architecture
Description	Phosducin (PHD) (33 kDa phototransducing protein) (MEKA protein).

PHOS_MOUSE
NC score	0.269814 (rank : 8)	θ value	0.0330416 (rank : 9)
Query Neighborhood Hits	31	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QW08	Gene names	Pdc, Rpr1
Domain Architecture
Description	Phosducin (PHD) (33 kDa phototransducing protein) (Rod photoreceptor 1) (RPR-1).

TXNL2_MOUSE
NC score	0.255300 (rank : 9)	θ value	0.00298849 (rank : 7)
Query Neighborhood Hits	31	Target Neighborhood Hits	54	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CQM9, Q9JLZ2	Gene names	Txnl2, Picot
Domain Architecture
Description	Thioredoxin-like protein 2 (PKC-interacting cousin of thioredoxin) (PKC-theta-interacting protein) (PKCq-interacting protein).

TXNL2_HUMAN
NC score	0.226620 (rank : 10)	θ value	0.0431538 (rank : 12)
Query Neighborhood Hits	31	Target Neighborhood Hits	59	Shared Neighborhood Hits	17
SwissProt Accessions	O76003, Q96CE0, Q9P1B0, Q9P1B1	Gene names	TXNL2, PICOT
Domain Architecture
Description	Thioredoxin-like protein 2 (PKC-interacting cousin of thioredoxin) (PKC-theta-interacting protein) (PKCq-interacting protein).

PHLP_HUMAN
NC score	0.198911 (rank : 11)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	31	Target Neighborhood Hits	28	Shared Neighborhood Hits	9
SwissProt Accessions	Q13371, Q96AF1, Q9UEW7, Q9UFL0	Gene names	PDCL
Domain Architecture
Description	Phosducin-like protein (PHLP).

PHLP_MOUSE
NC score	0.191939 (rank : 12)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	31	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DBX2, Q3TKI0	Gene names	Pdcl
Domain Architecture
Description	Phosducin-like protein (PHLP).

THIOM_MOUSE
NC score	0.188190 (rank : 13)	θ value	0.0431538 (rank : 11)
Query Neighborhood Hits	31	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	P97493, Q545D5	Gene names	Txn2
Domain Architecture
Description	Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2).

THIOM_HUMAN
NC score	0.187756 (rank : 14)	θ value	0.0431538 (rank : 10)
Query Neighborhood Hits	31	Target Neighborhood Hits	46	Shared Neighborhood Hits	15
SwissProt Accessions	Q99757, Q5JZA0, Q9UH29	Gene names	TXN2, TRX2
Domain Architecture
Description	Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2).

THIO_HUMAN
NC score	0.100726 (rank : 15)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	31	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	P10599, Q96KI3	Gene names	TXN, TRDX, TRX, TRX1
Domain Architecture
Description	Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP).

THIO_MOUSE
NC score	0.092604 (rank : 16)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	31	Target Neighborhood Hits	39	Shared Neighborhood Hits	12
SwissProt Accessions	P10639, Q52KC4, Q9D8R0	Gene names	Txn, Txn1
Domain Architecture
Description	Thioredoxin (Trx) (ATL-derived factor) (ADF).

TXND8_HUMAN
NC score	0.086894 (rank : 17)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	31	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	Q6A555, Q5T934	Gene names	TXNDC8, SPTRX3, TRX6
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 8 (Spermatid-specific thioredoxin-3) (Sptrx-3) (Thioredoxin-6).

TXND8_MOUSE
NC score	0.072650 (rank : 18)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	31	Target Neighborhood Hits	41	Shared Neighborhood Hits	10
SwissProt Accessions	Q69AB2, Q78Y03, Q80YE0, Q9CQ96	Gene names	Txndc8, Sptrx3, Trx6
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 8 (Spermatid-specific thioredoxin-3) (Sptrx-3) (Thioredoxin-6).

TXND5_MOUSE
NC score	0.067933 (rank : 19)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	31	Target Neighborhood Hits	52	Shared Neighborhood Hits	12
SwissProt Accessions	Q91W90, Q8R1I6	Gene names	Txndc5, Tlp46
Domain Architecture
Description	Thioredoxin domain-containing protein 5 precursor (Thioredoxin-like protein p46) (Endoplasmic reticulum protein ERp46) (Plasma cell- specific thioredoxin-related protein) (PC-TRP).

PDIA4_HUMAN
NC score	0.065766 (rank : 20)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	31	Target Neighborhood Hits	60	Shared Neighborhood Hits	12
SwissProt Accessions	P13667	Gene names	PDIA4, ERP70, ERP72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

GLRX5_HUMAN
NC score	0.060396 (rank : 21)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	31	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q86SX6, Q3YML0, Q86WY3, Q8IZ54	Gene names	GLRX5, C14orf87
Domain Architecture	No domain graphic available
Description	Glutaredoxin-related protein 5.

GLRX5_MOUSE
NC score	0.060306 (rank : 22)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	31	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q80Y14, Q3YML1, Q9D6E9	Gene names	Glrx5
Domain Architecture	No domain graphic available
Description	Glutaredoxin-related protein 5.

TXND5_HUMAN
NC score	0.053277 (rank : 23)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	31	Target Neighborhood Hits	54	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NBS9, Q8ND33, Q8TCT2, Q9BVH9	Gene names	TXNDC5, TLP46
Domain Architecture
Description	Thioredoxin domain-containing protein 5 precursor (Thioredoxin-like protein p46) (Endoplasmic reticulum protein ERp46).

PDIA5_HUMAN
NC score	0.052545 (rank : 24)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	31	Target Neighborhood Hits	42	Shared Neighborhood Hits	11
SwissProt Accessions	Q14554	Gene names	PDIA5, PDIR
Domain Architecture
Description	Protein disulfide-isomerase A5 precursor (EC 5.3.4.1) (Protein disulfide isomerase-related protein).

TXNL1_MOUSE
NC score	0.051568 (rank : 25)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	31	Target Neighborhood Hits	29	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CDN6, O70379, Q3TI92	Gene names	Txnl1, Trp32, Txnl
Domain Architecture	No domain graphic available
Description	Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein).

TXNL1_HUMAN
NC score	0.051531 (rank : 26)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	31	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	O43396	Gene names	TXNL1, TRP32, TXL, TXNL
Domain Architecture
Description	Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein).

TXND2_HUMAN
NC score	0.047814 (rank : 27)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	31	Target Neighborhood Hits	793	Shared Neighborhood Hits	13
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

UTRO_HUMAN
NC score	0.033887 (rank : 28)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	31	Target Neighborhood Hits	960	Shared Neighborhood Hits	11
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

STXB4_HUMAN
NC score	0.031499 (rank : 29)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	31	Target Neighborhood Hits	616	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

NIN_HUMAN
NC score	0.023031 (rank : 30)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	31	Target Neighborhood Hits	1416	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

RUFY2_MOUSE
NC score	0.021470 (rank : 31)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	31	Target Neighborhood Hits	820	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

HSP74_MOUSE
NC score	0.020991 (rank : 32)	θ value	0.813845 (rank : 14)
Query Neighborhood Hits	31	Target Neighborhood Hits	257	Shared Neighborhood Hits	5
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

GOGB1_HUMAN
NC score	0.018227 (rank : 33)	θ value	1.81305 (rank : 17)
Query Neighborhood Hits	31	Target Neighborhood Hits	2297	Shared Neighborhood Hits	13
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CCD46_HUMAN
NC score	0.017731 (rank : 34)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	31	Target Neighborhood Hits	1430	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

PRC1_HUMAN
NC score	0.016737 (rank : 35)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	31	Target Neighborhood Hits	328	Shared Neighborhood Hits	8
SwissProt Accessions	O43663, Q9BSB6	Gene names	PRC1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

DMXL2_HUMAN
NC score	0.012115 (rank : 36)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	31	Target Neighborhood Hits	374	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

STK10_MOUSE
NC score	0.010737 (rank : 37)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	31	Target Neighborhood Hits	2132	Shared Neighborhood Hits	15
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

SLK_HUMAN
NC score	0.009643 (rank : 38)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	31	Target Neighborhood Hits	1775	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

ITSN1_MOUSE
NC score	0.008992 (rank : 39)	θ value	8.99809 (rank : 29)
Query Neighborhood Hits	31	Target Neighborhood Hits	1669	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

SLK_MOUSE
NC score	0.008934 (rank : 40)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	31	Target Neighborhood Hits	1798	Shared Neighborhood Hits	11
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).