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Network neighborhood for query Sequence : SEN2_HUMAN

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SEN2_HUMAN
SwissProt Accessions	Q8NCE0, Q8WTW7, Q9BPU7	Gene names	TSEN2, SEN2
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen2 (EC 3.1.27.9) (tRNA-intron endonuclease Sen2) (HsSen2 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SEN2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NCE0, Q8WTW7, Q9BPU7	Gene names	TSEN2, SEN2
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen2 (EC 3.1.27.9) (tRNA-intron endonuclease Sen2) (HsSen2 protein).

SEN2_MOUSE
θ value	6.32649e-179 (rank : 2)	NC score	0.983633 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P7W5, Q3UYG6	Gene names	Tsen2, Sen2
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen2 (EC 3.1.27.9) (tRNA-intron endonuclease Sen2).

SEN34_MOUSE
θ value	0.125558 (rank : 3)	NC score	0.126909 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	158	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

SEN34_HUMAN
θ value	0.62314 (rank : 4)	NC score	0.115855 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BSV6, Q9BVT1, Q9H6H5	Gene names	TSEN34, LENG5, SEN34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (HsSen34) (Leukocyte receptor cluster member 5).

SIX5_MOUSE
θ value	1.06291 (rank : 5)	NC score	0.024758 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	354	Shared Neighborhood Hits	2
SwissProt Accessions	P70178	Gene names	Six5, Dmahp
Domain Architecture
Description	Homeobox protein SIX5 (DM locus-associated homeodomain protein homolog).

CIC_HUMAN
θ value	4.03905 (rank : 6)	NC score	0.014202 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	992	Shared Neighborhood Hits	4
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

ZNF96_HUMAN
θ value	5.27518 (rank : 7)	NC score	0.001039 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	869	Shared Neighborhood Hits	3
SwissProt Accessions	O43309, O43724	Gene names	ZNF96, KIAA0426, ZNF305, ZSCAN12
Domain Architecture
Description	Zinc finger protein 96 (Zinc finger protein 305) (Zinc finger and SCAN domain-containing protein 12).

ANX11_HUMAN
θ value	6.88961 (rank : 8)	NC score	0.007866 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	192	Shared Neighborhood Hits	3
SwissProt Accessions	P50995	Gene names	ANXA11, ANX11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50) (56 kDa autoantigen).

HEMK1_MOUSE
θ value	6.88961 (rank : 9)	NC score	0.022649 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q921L7	Gene names	Hemk1
Domain Architecture	No domain graphic available
Description	HemK methyltransferase family member 1 (EC 2.1.1.-).

PCDC2_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.003307 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	185	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5I4, Q9Y5F4	Gene names	PCDHAC2
Domain Architecture
Description	Protocadherin alpha C2 precursor (PCDH-alpha-C2).

SOX4_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.010077 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	Q06945	Gene names	SOX4
Domain Architecture
Description	Transcription factor SOX-4.

BD02_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.033099 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	O15263, Q52LC0	Gene names	DEFB4, DEFB102, DEFB2
Domain Architecture	No domain graphic available
Description	Beta-defensin 2 precursor (BD-2) (hBD-2) (Defensin, beta 2) (Skin- antimicrobial peptide 1) (SAP1).

SALL2_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.003542 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	835	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y467, Q9Y4G1	Gene names	SALL2, KIAA0360, SAL2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Zinc finger protein SALL2) (HSal2).

Hits sorted by NC score

SEN2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NCE0, Q8WTW7, Q9BPU7	Gene names	TSEN2, SEN2
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen2 (EC 3.1.27.9) (tRNA-intron endonuclease Sen2) (HsSen2 protein).

SEN2_MOUSE
NC score	0.983633 (rank : 2)	θ value	6.32649e-179 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P7W5, Q3UYG6	Gene names	Tsen2, Sen2
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen2 (EC 3.1.27.9) (tRNA-intron endonuclease Sen2).

SEN34_MOUSE
NC score	0.126909 (rank : 3)	θ value	0.125558 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	158	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

SEN34_HUMAN
NC score	0.115855 (rank : 4)	θ value	0.62314 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BSV6, Q9BVT1, Q9H6H5	Gene names	TSEN34, LENG5, SEN34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (HsSen34) (Leukocyte receptor cluster member 5).

BD02_HUMAN
NC score	0.033099 (rank : 5)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	O15263, Q52LC0	Gene names	DEFB4, DEFB102, DEFB2
Domain Architecture	No domain graphic available
Description	Beta-defensin 2 precursor (BD-2) (hBD-2) (Defensin, beta 2) (Skin- antimicrobial peptide 1) (SAP1).

SIX5_MOUSE
NC score	0.024758 (rank : 6)	θ value	1.06291 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	354	Shared Neighborhood Hits	2
SwissProt Accessions	P70178	Gene names	Six5, Dmahp
Domain Architecture
Description	Homeobox protein SIX5 (DM locus-associated homeodomain protein homolog).

HEMK1_MOUSE
NC score	0.022649 (rank : 7)	θ value	6.88961 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q921L7	Gene names	Hemk1
Domain Architecture	No domain graphic available
Description	HemK methyltransferase family member 1 (EC 2.1.1.-).

CIC_HUMAN
NC score	0.014202 (rank : 8)	θ value	4.03905 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	992	Shared Neighborhood Hits	4
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SOX4_HUMAN
NC score	0.010077 (rank : 9)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	Q06945	Gene names	SOX4
Domain Architecture
Description	Transcription factor SOX-4.

ANX11_HUMAN
NC score	0.007866 (rank : 10)	θ value	6.88961 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	192	Shared Neighborhood Hits	3
SwissProt Accessions	P50995	Gene names	ANXA11, ANX11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50) (56 kDa autoantigen).

SALL2_HUMAN
NC score	0.003542 (rank : 11)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	835	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y467, Q9Y4G1	Gene names	SALL2, KIAA0360, SAL2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Zinc finger protein SALL2) (HSal2).

PCDC2_HUMAN
NC score	0.003307 (rank : 12)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	185	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5I4, Q9Y5F4	Gene names	PCDHAC2
Domain Architecture
Description	Protocadherin alpha C2 precursor (PCDH-alpha-C2).

ZNF96_HUMAN
NC score	0.001039 (rank : 13)	θ value	5.27518 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	869	Shared Neighborhood Hits	3
SwissProt Accessions	O43309, O43724	Gene names	ZNF96, KIAA0426, ZNF305, ZSCAN12
Domain Architecture
Description	Zinc finger protein 96 (Zinc finger protein 305) (Zinc finger and SCAN domain-containing protein 12).