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Network neighborhood for query Sequence : RIOK2_HUMAN

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RIOK2_HUMAN
SwissProt Accessions	Q9BVS4, Q9NUT0	Gene names	RIOK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RIOK2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	125	Target Neighborhood Hits	125	Shared Neighborhood Hits	125
SwissProt Accessions	Q9BVS4, Q9NUT0	Gene names	RIOK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

RIOK2_MOUSE
θ value	0 (rank : 2)	NC score	0.959589 (rank : 2)
Query Neighborhood Hits	125	Target Neighborhood Hits	82	Shared Neighborhood Hits	43
SwissProt Accessions	Q9CQS5, Q91XF3	Gene names	Riok2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

RIOK1_HUMAN
θ value	9.59137e-10 (rank : 3)	NC score	0.420495 (rank : 3)
Query Neighborhood Hits	125	Target Neighborhood Hits	86	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BRS2, Q8NDC8, Q96NV9	Gene names	RIOK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (RIO kinase 1).

RIOK3_MOUSE
θ value	5.81887e-07 (rank : 4)	NC score	0.352499 (rank : 4)
Query Neighborhood Hits	125	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DBU3, Q8CIC1	Gene names	Riok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3).

RIOK3_HUMAN
θ value	2.21117e-06 (rank : 5)	NC score	0.343546 (rank : 5)
Query Neighborhood Hits	125	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	O14730, Q8IXN9	Gene names	RIOK3, SUDD
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog).

HTSF1_MOUSE
θ value	3.19293e-05 (rank : 6)	NC score	0.144803 (rank : 6)
Query Neighborhood Hits	125	Target Neighborhood Hits	425	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

NRK_HUMAN
θ value	0.00102713 (rank : 7)	NC score	0.071649 (rank : 12)
Query Neighborhood Hits	125	Target Neighborhood Hits	931	Shared Neighborhood Hits	58
SwissProt Accessions	Q7Z2Y5, Q32ND6, Q5H9K2, Q6ZMP2	Gene names	NRK
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1).

HTSF1_HUMAN
θ value	0.00665767 (rank : 8)	NC score	0.121501 (rank : 7)
Query Neighborhood Hits	125	Target Neighborhood Hits	408	Shared Neighborhood Hits	15
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

NRK_MOUSE
θ value	0.0148317 (rank : 9)	NC score	0.069207 (rank : 13)
Query Neighborhood Hits	125	Target Neighborhood Hits	899	Shared Neighborhood Hits	58
SwissProt Accessions	Q9R0G8, Q6NV55, Q8C9S9, Q9R0S4	Gene names	Nrk, Nesk
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1) (Nck-interacting kinase-like embryo specific kinase) (NIK-like embryo-specific kinase) (NESK).

BMS1_HUMAN
θ value	0.0193708 (rank : 10)	NC score	0.107250 (rank : 8)
Query Neighborhood Hits	125	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q14692, Q86XJ9	Gene names	BMS1L, KIAA0187
Domain Architecture
Description	Ribosome biogenesis protein BMS1 homolog.

RPGR1_MOUSE
θ value	0.0252991 (rank : 11)	NC score	0.064604 (rank : 15)
Query Neighborhood Hits	125	Target Neighborhood Hits	713	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

DMP1_MOUSE
θ value	0.0961366 (rank : 12)	NC score	0.080032 (rank : 9)
Query Neighborhood Hits	125	Target Neighborhood Hits	498	Shared Neighborhood Hits	33
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

YTDC1_HUMAN
θ value	0.0961366 (rank : 13)	NC score	0.073617 (rank : 11)
Query Neighborhood Hits	125	Target Neighborhood Hits	458	Shared Neighborhood Hits	30
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

AP3B2_MOUSE
θ value	0.163984 (rank : 14)	NC score	0.044256 (rank : 71)
Query Neighborhood Hits	125	Target Neighborhood Hits	246	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

M4K3_HUMAN
θ value	0.163984 (rank : 15)	NC score	0.058446 (rank : 20)
Query Neighborhood Hits	125	Target Neighborhood Hits	857	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IVH8, Q8IVH7, Q9UDM5, Q9Y6R5	Gene names	MAP4K3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase-related protein kinase) (GLK).

CD2L1_HUMAN
θ value	0.365318 (rank : 16)	NC score	0.045507 (rank : 66)
Query Neighborhood Hits	125	Target Neighborhood Hits	1467	Shared Neighborhood Hits	72
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CHK1_MOUSE
θ value	0.365318 (rank : 17)	NC score	0.050735 (rank : 44)
Query Neighborhood Hits	125	Target Neighborhood Hits	839	Shared Neighborhood Hits	55
SwissProt Accessions	O35280, O54925, Q8CI40, Q9D0N2	Gene names	Chek1, Chk1
Domain Architecture
Description	Serine/threonine-protein kinase Chk1 (EC 2.7.11.1).

IF2P_HUMAN
θ value	0.365318 (rank : 18)	NC score	0.039307 (rank : 77)
Query Neighborhood Hits	125	Target Neighborhood Hits	889	Shared Neighborhood Hits	22
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

CD2L2_HUMAN
θ value	0.47712 (rank : 19)	NC score	0.044636 (rank : 70)
Query Neighborhood Hits	125	Target Neighborhood Hits	1439	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

SRCH_HUMAN
θ value	0.47712 (rank : 20)	NC score	0.058318 (rank : 22)
Query Neighborhood Hits	125	Target Neighborhood Hits	225	Shared Neighborhood Hits	10
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

TF2AY_MOUSE
θ value	0.47712 (rank : 21)	NC score	0.052056 (rank : 40)
Query Neighborhood Hits	125	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4I4, Q99PM2, Q9DAF4	Gene names	Gtf2a1lf, Alf
Domain Architecture
Description	TFIIA-alpha and beta-like factor (General transcription factor II A, 1-like factor).

CHD2_HUMAN
θ value	0.62314 (rank : 22)	NC score	0.024580 (rank : 98)
Query Neighborhood Hits	125	Target Neighborhood Hits	360	Shared Neighborhood Hits	14
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

KPCB_HUMAN
θ value	0.62314 (rank : 23)	NC score	0.055800 (rank : 27)
Query Neighborhood Hits	125	Target Neighborhood Hits	1121	Shared Neighborhood Hits	57
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_MOUSE
θ value	0.62314 (rank : 24)	NC score	0.055943 (rank : 26)
Query Neighborhood Hits	125	Target Neighborhood Hits	1117	Shared Neighborhood Hits	57
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

RP1L1_HUMAN
θ value	0.62314 (rank : 25)	NC score	0.033393 (rank : 86)
Query Neighborhood Hits	125	Target Neighborhood Hits	1072	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

FBXW7_HUMAN
θ value	0.813845 (rank : 26)	NC score	0.012333 (rank : 118)
Query Neighborhood Hits	125	Target Neighborhood Hits	433	Shared Neighborhood Hits	8
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

DMP1_HUMAN
θ value	1.06291 (rank : 27)	NC score	0.074942 (rank : 10)
Query Neighborhood Hits	125	Target Neighborhood Hits	491	Shared Neighborhood Hits	33
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

KPCA_HUMAN
θ value	1.06291 (rank : 28)	NC score	0.055062 (rank : 29)
Query Neighborhood Hits	125	Target Neighborhood Hits	1070	Shared Neighborhood Hits	57
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

TRI44_HUMAN
θ value	1.06291 (rank : 29)	NC score	0.039348 (rank : 76)
Query Neighborhood Hits	125	Target Neighborhood Hits	393	Shared Neighborhood Hits	16
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TTK_HUMAN
θ value	1.06291 (rank : 30)	NC score	0.045516 (rank : 65)
Query Neighborhood Hits	125	Target Neighborhood Hits	816	Shared Neighborhood Hits	55
SwissProt Accessions	P33981	Gene names	TTK, MPS1L1
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT).

ASPX_MOUSE
θ value	1.38821 (rank : 31)	NC score	0.048788 (rank : 52)
Query Neighborhood Hits	125	Target Neighborhood Hits	49	Shared Neighborhood Hits	6
SwissProt Accessions	P50289, Q9DAM6	Gene names	Acrv1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1) (MSA- 63).

EXOC2_MOUSE
θ value	1.38821 (rank : 32)	NC score	0.046989 (rank : 59)
Query Neighborhood Hits	125	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D4H1	Gene names	Exoc2, Sec5, Sec5l1
Domain Architecture
Description	Exocyst complex component 2 (Exocyst complex component Sec5).

MASTL_HUMAN
θ value	1.38821 (rank : 33)	NC score	0.058362 (rank : 21)
Query Neighborhood Hits	125	Target Neighborhood Hits	894	Shared Neighborhood Hits	55
SwissProt Accessions	Q96GX5, Q5T8D5, Q5T8D7, Q8NCD6, Q96SJ5	Gene names	MASTL, THC2
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

TNNT3_MOUSE
θ value	1.38821 (rank : 34)	NC score	0.033604 (rank : 85)
Query Neighborhood Hits	125	Target Neighborhood Hits	317	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QZ47, O35575, O35576, O35577, O35578, O35579, O35580, O35581, O35582, O35583, O35584, O35585, P97456, Q99L89, Q9QZ46	Gene names	Tnnt3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT).

TSSK4_MOUSE
θ value	1.38821 (rank : 35)	NC score	0.047263 (rank : 58)
Query Neighborhood Hits	125	Target Neighborhood Hits	840	Shared Neighborhood Hits	55
SwissProt Accessions	Q9D411	Gene names	Tssk4
Domain Architecture	No domain graphic available
Description	Testis-specific serine/threonine-protein kinase 4 (EC 2.7.11.1) (TSSK- 4) (Testis-specific kinase 4) (TSK-4).

CO5_MOUSE
θ value	1.81305 (rank : 36)	NC score	0.024462 (rank : 99)
Query Neighborhood Hits	125	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P06684	Gene names	C5, Hc
Domain Architecture
Description	Complement C5 precursor (Hemolytic complement) [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

GP158_MOUSE
θ value	1.81305 (rank : 37)	NC score	0.028201 (rank : 92)
Query Neighborhood Hits	125	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

HUNK_MOUSE
θ value	1.81305 (rank : 38)	NC score	0.046898 (rank : 60)
Query Neighborhood Hits	125	Target Neighborhood Hits	874	Shared Neighborhood Hits	55
SwissProt Accessions	O88866	Gene names	Hunk, Makv
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V).

KPCE_HUMAN
θ value	1.81305 (rank : 39)	NC score	0.054415 (rank : 31)
Query Neighborhood Hits	125	Target Neighborhood Hits	906	Shared Neighborhood Hits	58
SwissProt Accessions	Q02156, Q53SL4, Q53SM5, Q9UE81	Gene names	PRKCE, PKCE
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

KPCE_MOUSE
θ value	1.81305 (rank : 40)	NC score	0.054167 (rank : 32)
Query Neighborhood Hits	125	Target Neighborhood Hits	906	Shared Neighborhood Hits	57
SwissProt Accessions	P16054	Gene names	Prkce, Pkce, Pkcea
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

SCG1_HUMAN
θ value	1.81305 (rank : 41)	NC score	0.039672 (rank : 75)
Query Neighborhood Hits	125	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	P05060, Q9BQV6, Q9UJA6	Gene names	CHGB, SCG1
Domain Architecture
Description	Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB) [Contains: GAWK peptide; CCB peptide].

AP3B1_HUMAN
θ value	2.36792 (rank : 42)	NC score	0.037116 (rank : 82)
Query Neighborhood Hits	125	Target Neighborhood Hits	283	Shared Neighborhood Hits	15
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

E2AK4_HUMAN
θ value	2.36792 (rank : 43)	NC score	0.056358 (rank : 25)
Query Neighborhood Hits	125	Target Neighborhood Hits	1012	Shared Neighborhood Hits	58
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).

E2AK4_MOUSE
θ value	2.36792 (rank : 44)	NC score	0.057642 (rank : 23)
Query Neighborhood Hits	125	Target Neighborhood Hits	984	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QZ05, Q6GQT4, Q6ZPT5, Q8C5S0, Q8CIF5, Q9CT30, Q9CUV9, Q9ESB6, Q9ESB7, Q9ESB8	Gene names	Eif2ak4, Gcn2, Kiaa1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein) (mGCN2).

HUNK_HUMAN
θ value	2.36792 (rank : 45)	NC score	0.046398 (rank : 61)
Query Neighborhood Hits	125	Target Neighborhood Hits	884	Shared Neighborhood Hits	55
SwissProt Accessions	P57058	Gene names	HUNK, MAKV
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19).

KKCC2_HUMAN
θ value	2.36792 (rank : 46)	NC score	0.050050 (rank : 48)
Query Neighborhood Hits	125	Target Neighborhood Hits	852	Shared Neighborhood Hits	55
SwissProt Accessions	Q96RR4, O94883, Q8IUG2, Q8IUG3, Q8N3I4, Q8WY03, Q8WY04, Q8WY05, Q8WY06, Q96RP1, Q96RP2, Q96RR3, Q9BWE9, Q9UER3, Q9UES2, Q9Y5N2	Gene names	CAMKK2, CAMKKB, KIAA0787
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta).

KKCC2_MOUSE
θ value	2.36792 (rank : 47)	NC score	0.050087 (rank : 47)
Query Neighborhood Hits	125	Target Neighborhood Hits	855	Shared Neighborhood Hits	55
SwissProt Accessions	Q8C078, Q80TS0, Q8BXM8, Q8C0G3, Q8CH42, Q8QZT7	Gene names	Camkk2, Kiaa0787
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta).

M4K2_MOUSE
θ value	2.36792 (rank : 48)	NC score	0.054911 (rank : 30)
Query Neighborhood Hits	125	Target Neighborhood Hits	843	Shared Neighborhood Hits	55
SwissProt Accessions	Q61161	Gene names	Map4k2, Rab8ip
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GCK) (Rab8-interacting protein).

MASTL_MOUSE
θ value	2.36792 (rank : 49)	NC score	0.057195 (rank : 24)
Query Neighborhood Hits	125	Target Neighborhood Hits	862	Shared Neighborhood Hits	56
SwissProt Accessions	Q8C0P0, Q5RJW0, Q6NXX9, Q8BVF3, Q9CZH9, Q9D9V0	Gene names	Mastl
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

SSRP1_HUMAN
θ value	2.36792 (rank : 50)	NC score	0.031264 (rank : 89)
Query Neighborhood Hits	125	Target Neighborhood Hits	187	Shared Neighborhood Hits	7
SwissProt Accessions	Q08945, Q5BJG8	Gene names	SSRP1, FACT80
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (FACT 80 kDa subunit) (FACTp80) (Chromatin- specific transcription elongation factor 80 kDa subunit) (Structure- specific recognition protein 1) (hSSRP1) (Recombination signal sequence recognition protein 1) (T160).

SSRP1_MOUSE
θ value	2.36792 (rank : 51)	NC score	0.032311 (rank : 87)
Query Neighborhood Hits	125	Target Neighborhood Hits	193	Shared Neighborhood Hits	7
SwissProt Accessions	Q08943, Q3U9Z2, Q3UJ75, Q4V9U4, Q8CGA6	Gene names	Ssrp1
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Structure-specific recognition protein 1) (Recombination signal sequence recognition protein 1) (T160).

TAI12_HUMAN
θ value	2.36792 (rank : 52)	NC score	0.031695 (rank : 88)
Query Neighborhood Hits	125	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H175	Gene names	TAIP12, C12orf22
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 12 (TAIP-12).

TRI44_MOUSE
θ value	2.36792 (rank : 53)	NC score	0.035390 (rank : 84)
Query Neighborhood Hits	125	Target Neighborhood Hits	327	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

BASP_MOUSE
θ value	3.0926 (rank : 54)	NC score	0.035963 (rank : 83)
Query Neighborhood Hits	125	Target Neighborhood Hits	260	Shared Neighborhood Hits	14
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BPTF_HUMAN
θ value	3.0926 (rank : 55)	NC score	0.027824 (rank : 93)
Query Neighborhood Hits	125	Target Neighborhood Hits	786	Shared Neighborhood Hits	28
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CCKAR_MOUSE
θ value	3.0926 (rank : 56)	NC score	0.001141 (rank : 128)
Query Neighborhood Hits	125	Target Neighborhood Hits	931	Shared Neighborhood Hits	2
SwissProt Accessions	O08786, Q8VCC7, Q9DBV6	Gene names	Cckar
Domain Architecture
Description	Cholecystokinin type A receptor (CCK-A receptor) (CCK-AR) (Cholecystokinin-1 receptor) (CCK1-R).

CHD4_MOUSE
θ value	3.0926 (rank : 57)	NC score	0.020977 (rank : 104)
Query Neighborhood Hits	125	Target Neighborhood Hits	408	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHK1_HUMAN
θ value	3.0926 (rank : 58)	NC score	0.045545 (rank : 64)
Query Neighborhood Hits	125	Target Neighborhood Hits	843	Shared Neighborhood Hits	54
SwissProt Accessions	O14757	Gene names	CHEK1, CHK1
Domain Architecture
Description	Serine/threonine-protein kinase Chk1 (EC 2.7.11.1).

KS6B2_MOUSE
θ value	3.0926 (rank : 59)	NC score	0.048311 (rank : 55)
Query Neighborhood Hits	125	Target Neighborhood Hits	871	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z1M4	Gene names	Rps6kb2
Domain Architecture
Description	Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2).

LAS1L_HUMAN
θ value	3.0926 (rank : 60)	NC score	0.038834 (rank : 78)
Query Neighborhood Hits	125	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4W2, Q5JXQ0, Q8TEN5, Q9H9V5	Gene names	LAS1L
Domain Architecture	No domain graphic available
Description	LAS1-like protein.

MACF4_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.012209 (rank : 119)
Query Neighborhood Hits	125	Target Neighborhood Hits	1321	Shared Neighborhood Hits	26
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

NEB1_HUMAN
θ value	3.0926 (rank : 62)	NC score	0.022957 (rank : 103)
Query Neighborhood Hits	125	Target Neighborhood Hits	829	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

PTMA_HUMAN
θ value	3.0926 (rank : 63)	NC score	0.065043 (rank : 14)
Query Neighborhood Hits	125	Target Neighborhood Hits	88	Shared Neighborhood Hits	10
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

ST32B_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.049017 (rank : 51)
Query Neighborhood Hits	125	Target Neighborhood Hits	830	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NY57, Q6UXH3, Q8IY14	Gene names	STK32B
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32B (EC 2.7.11.1) (YANK2).

ST32B_MOUSE
θ value	3.0926 (rank : 65)	NC score	0.048706 (rank : 53)
Query Neighborhood Hits	125	Target Neighborhood Hits	828	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JJX8, Q7TMD3, Q8C4E0	Gene names	Stk32b, Stk32
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32B (EC 2.7.11.1).

TTBK2_MOUSE
θ value	3.0926 (rank : 66)	NC score	0.037359 (rank : 81)
Query Neighborhood Hits	125	Target Neighborhood Hits	811	Shared Neighborhood Hits	58
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

EXOC2_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.040932 (rank : 74)
Query Neighborhood Hits	125	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q96KP1, Q5JPC8, Q96AN6, Q9NUZ8, Q9UJM7	Gene names	EXOC2, SEC5, SEC5L1
Domain Architecture
Description	Exocyst complex component 2 (Exocyst complex component Sec5).

IQEC3_MOUSE
θ value	4.03905 (rank : 68)	NC score	0.013545 (rank : 117)
Query Neighborhood Hits	125	Target Neighborhood Hits	274	Shared Neighborhood Hits	10
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IWS1_MOUSE
θ value	4.03905 (rank : 69)	NC score	0.063410 (rank : 17)
Query Neighborhood Hits	125	Target Neighborhood Hits	1258	Shared Neighborhood Hits	53
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KPCA_MOUSE
θ value	4.03905 (rank : 70)	NC score	0.052900 (rank : 36)
Query Neighborhood Hits	125	Target Neighborhood Hits	1067	Shared Neighborhood Hits	57
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCD_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.051620 (rank : 41)
Query Neighborhood Hits	125	Target Neighborhood Hits	900	Shared Neighborhood Hits	55
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

M4K5_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.052652 (rank : 37)
Query Neighborhood Hits	125	Target Neighborhood Hits	845	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y4K4, Q8IYF6	Gene names	MAP4K5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5) (Kinase homologous to SPS1/STE20) (KHS).

M4K5_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.052907 (rank : 35)
Query Neighborhood Hits	125	Target Neighborhood Hits	839	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BPM2, Q6PEQ2, Q8C3U5, Q8CGF3, Q99LM7, Q9CX73	Gene names	Map4k5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5).

MAVS_MOUSE
θ value	4.03905 (rank : 74)	NC score	0.025492 (rank : 96)
Query Neighborhood Hits	125	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VCF0	Gene names	Mavs, Ips1, Visa
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif).

PCLO_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.028661 (rank : 91)
Query Neighborhood Hits	125	Target Neighborhood Hits	2046	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

ST32A_HUMAN
θ value	4.03905 (rank : 76)	NC score	0.047497 (rank : 57)
Query Neighborhood Hits	125	Target Neighborhood Hits	834	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WU08	Gene names	STK32A
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32A (EC 2.7.11.1) (YANK1).

STK39_MOUSE
θ value	4.03905 (rank : 77)	NC score	0.045250 (rank : 68)
Query Neighborhood Hits	125	Target Neighborhood Hits	915	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z1W9, Q80W13	Gene names	Stk39, Spak
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39).

TAI12_MOUSE
θ value	4.03905 (rank : 78)	NC score	0.029108 (rank : 90)
Query Neighborhood Hits	125	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGQ2, Q3UIH1	Gene names	Taip12
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 12 (TAIP-12).

ANK2_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.008764 (rank : 123)
Query Neighborhood Hits	125	Target Neighborhood Hits	1615	Shared Neighborhood Hits	29
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CD2L1_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.042689 (rank : 73)
Query Neighborhood Hits	125	Target Neighborhood Hits	1463	Shared Neighborhood Hits	71
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

CHD4_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.019640 (rank : 106)
Query Neighborhood Hits	125	Target Neighborhood Hits	365	Shared Neighborhood Hits	13
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CJ078_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.026923 (rank : 94)
Query Neighborhood Hits	125	Target Neighborhood Hits	61	Shared Neighborhood Hits	5
SwissProt Accessions	Q86XK3, Q5JT40, Q8WW47	Gene names	C10orf78
Domain Architecture	No domain graphic available
Description	Protein C10orf78.

CP250_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.014866 (rank : 113)
Query Neighborhood Hits	125	Target Neighborhood Hits	1805	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

KPCG_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.053161 (rank : 33)
Query Neighborhood Hits	125	Target Neighborhood Hits	1126	Shared Neighborhood Hits	57
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_MOUSE
θ value	5.27518 (rank : 85)	NC score	0.053139 (rank : 34)
Query Neighborhood Hits	125	Target Neighborhood Hits	1123	Shared Neighborhood Hits	57
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCT_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.052363 (rank : 39)
Query Neighborhood Hits	125	Target Neighborhood Hits	897	Shared Neighborhood Hits	55
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

MAST1_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.050185 (rank : 46)
Query Neighborhood Hits	125	Target Neighborhood Hits	1146	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST1_MOUSE
θ value	5.27518 (rank : 88)	NC score	0.049977 (rank : 49)
Query Neighborhood Hits	125	Target Neighborhood Hits	1123	Shared Neighborhood Hits	57
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST4_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.051177 (rank : 42)
Query Neighborhood Hits	125	Target Neighborhood Hits	1804	Shared Neighborhood Hits	69
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

TAOK3_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.043705 (rank : 72)
Query Neighborhood Hits	125	Target Neighborhood Hits	1494	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

TFEB_MOUSE
θ value	5.27518 (rank : 91)	NC score	0.015918 (rank : 109)
Query Neighborhood Hits	125	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

TNNT3_HUMAN
θ value	5.27518 (rank : 92)	NC score	0.026654 (rank : 95)
Query Neighborhood Hits	125	Target Neighborhood Hits	327	Shared Neighborhood Hits	14
SwissProt Accessions	P45378, Q12975, Q12976, Q12977, Q12978, Q86TH6	Gene names	TNNT3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT) (Beta TnTF).

AN32B_MOUSE
θ value	6.88961 (rank : 93)	NC score	0.013764 (rank : 116)
Query Neighborhood Hits	125	Target Neighborhood Hits	236	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EST5	Gene names	Anp32b, Pal31
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31).

HNRPU_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.014361 (rank : 115)
Query Neighborhood Hits	125	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q00839, O75507, Q96HY9	Gene names	HNRPU, SAFA, U21.1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein U (hnRNP U) (Scaffold attachment factor A) (SAF-A) (p120) (pp120).

MAST3_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.049519 (rank : 50)
Query Neighborhood Hits	125	Target Neighborhood Hits	1128	Shared Neighborhood Hits	58
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

MP2K7_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.045063 (rank : 69)
Query Neighborhood Hits	125	Target Neighborhood Hits	833	Shared Neighborhood Hits	54
SwissProt Accessions	O14733, O14648, O14816, O60452, O60453	Gene names	MAP2K7, JNKK2, MKK7, PRKMK7
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 7 (EC 2.7.12.2) (MAP kinase kinase 7) (MAPKK 7) (MAPK/ERK kinase 7) (JNK-activating kinase 2) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2).

NEST_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.023324 (rank : 102)
Query Neighborhood Hits	125	Target Neighborhood Hits	1305	Shared Neighborhood Hits	36
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

NUMA1_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.011669 (rank : 121)
Query Neighborhood Hits	125	Target Neighborhood Hits	1523	Shared Neighborhood Hits	26
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

PCLO_MOUSE
θ value	6.88961 (rank : 99)	NC score	0.023391 (rank : 101)
Query Neighborhood Hits	125	Target Neighborhood Hits	2275	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TTK_MOUSE
θ value	6.88961 (rank : 100)	NC score	0.046166 (rank : 63)
Query Neighborhood Hits	125	Target Neighborhood Hits	803	Shared Neighborhood Hits	56
SwissProt Accessions	P35761	Gene names	Ttk, Esk
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (ESK) (PYT).

VPS54_MOUSE
θ value	6.88961 (rank : 101)	NC score	0.017216 (rank : 108)
Query Neighborhood Hits	125	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SPW0, Q8BPB3, Q8CFZ7, Q8CHL5, Q8R3R4, Q8R3X1	Gene names	Vps54
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p homolog).

ACINU_MOUSE
θ value	8.99809 (rank : 102)	NC score	0.019284 (rank : 107)
Query Neighborhood Hits	125	Target Neighborhood Hits	712	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

CDK7_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.037670 (rank : 80)
Query Neighborhood Hits	125	Target Neighborhood Hits	833	Shared Neighborhood Hits	54
SwissProt Accessions	P50613, Q9BS60, Q9UE19	Gene names	CDK7, MO15
Domain Architecture
Description	Cell division protein kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (CDK- activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1).

CDK7_MOUSE
θ value	8.99809 (rank : 104)	NC score	0.037834 (rank : 79)
Query Neighborhood Hits	125	Target Neighborhood Hits	835	Shared Neighborhood Hits	54
SwissProt Accessions	Q03147, Q99KK3	Gene names	Cdk7, Cdkn7, Crk4, Mo15, Mpk-7
Domain Architecture
Description	Cell division protein kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (CDK- activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinase) (CRK4).

CF153_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.025160 (rank : 97)
Query Neighborhood Hits	125	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	Q96EU6, Q9BRF6, Q9P0C8	Gene names	C6orf153
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf153.

CF153_MOUSE
θ value	8.99809 (rank : 106)	NC score	0.023993 (rank : 100)
Query Neighborhood Hits	125	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UFY0, Q91X71	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf153 homolog.

GOGB1_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.015870 (rank : 110)
Query Neighborhood Hits	125	Target Neighborhood Hits	2297	Shared Neighborhood Hits	44
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HXC10_MOUSE
θ value	8.99809 (rank : 108)	NC score	0.004453 (rank : 126)
Query Neighborhood Hits	125	Target Neighborhood Hits	417	Shared Neighborhood Hits	14
SwissProt Accessions	P31257, P31312, Q7TMT7	Gene names	Hoxc10, Hox-3.6, Hoxc-10
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-C10 (Hox-3.6).

IWS1_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.064116 (rank : 16)
Query Neighborhood Hits	125	Target Neighborhood Hits	1241	Shared Neighborhood Hits	53
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KPCD_MOUSE
θ value	8.99809 (rank : 110)	NC score	0.050967 (rank : 43)
Query Neighborhood Hits	125	Target Neighborhood Hits	888	Shared Neighborhood Hits	55
SwissProt Accessions	P28867, Q91V85, Q9Z333	Gene names	Prkcd, Pkcd
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCT_MOUSE
θ value	8.99809 (rank : 111)	NC score	0.050693 (rank : 45)
Query Neighborhood Hits	125	Target Neighborhood Hits	895	Shared Neighborhood Hits	55
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

LNP_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.015566 (rank : 111)
Query Neighborhood Hits	125	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9C0E8, Q2M2V8, Q2YD99, Q658W8, Q8N5V9, Q96MS5	Gene names	LNP, KIAA1715
Domain Architecture	No domain graphic available
Description	Protein lunapark.

M4K2_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.052455 (rank : 38)
Query Neighborhood Hits	125	Target Neighborhood Hits	850	Shared Neighborhood Hits	55
SwissProt Accessions	Q12851	Gene names	MAP4K2, GCK, RAB8IP
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GC kinase) (Rab8-interacting protein) (B lymphocyte serine/threonine-protein kinase).

MAST2_HUMAN
θ value	8.99809 (rank : 114)	NC score	0.048409 (rank : 54)
Query Neighborhood Hits	125	Target Neighborhood Hits	1189	Shared Neighborhood Hits	61
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST2_MOUSE
θ value	8.99809 (rank : 115)	NC score	0.047991 (rank : 56)
Query Neighborhood Hits	125	Target Neighborhood Hits	1110	Shared Neighborhood Hits	59
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MINT_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.019965 (rank : 105)
Query Neighborhood Hits	125	Target Neighborhood Hits	1514	Shared Neighborhood Hits	37
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NFM_MOUSE
θ value	8.99809 (rank : 117)	NC score	0.009124 (rank : 122)
Query Neighborhood Hits	125	Target Neighborhood Hits	1159	Shared Neighborhood Hits	28
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

PAK7_MOUSE
θ value	8.99809 (rank : 118)	NC score	0.045445 (rank : 67)
Query Neighborhood Hits	125	Target Neighborhood Hits	875	Shared Neighborhood Hits	55
SwissProt Accessions	Q8C015, Q3TQJ7, Q6RWS7	Gene names	Pak7, Pak5
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (p21-activated kinase 5).

PLXB3_MOUSE
θ value	8.99809 (rank : 119)	NC score	0.005109 (rank : 125)
Query Neighborhood Hits	125	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QY40, Q80TH8	Gene names	Plxnb3, Kiaa1206, Plxn6
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor (Plexin-6).

PTPRG_HUMAN
θ value	8.99809 (rank : 120)	NC score	0.003355 (rank : 127)
Query Neighborhood Hits	125	Target Neighborhood Hits	231	Shared Neighborhood Hits	6
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

RBM28_HUMAN
θ value	8.99809 (rank : 121)	NC score	0.008477 (rank : 124)
Query Neighborhood Hits	125	Target Neighborhood Hits	307	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NW13, Q96CV3	Gene names	RBM28
Domain Architecture	No domain graphic available
Description	RNA-binding protein 28 (RNA-binding motif protein 28).

SM1L2_HUMAN
θ value	8.99809 (rank : 122)	NC score	0.012067 (rank : 120)
Query Neighborhood Hits	125	Target Neighborhood Hits	1019	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

SMC3_HUMAN
θ value	8.99809 (rank : 123)	NC score	0.014919 (rank : 112)
Query Neighborhood Hits	125	Target Neighborhood Hits	1186	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	8.99809 (rank : 124)	NC score	0.014754 (rank : 114)
Query Neighborhood Hits	125	Target Neighborhood Hits	1187	Shared Neighborhood Hits	26
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

ST32A_MOUSE
θ value	8.99809 (rank : 125)	NC score	0.046388 (rank : 62)
Query Neighborhood Hits	125	Target Neighborhood Hits	833	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BGW6, Q7TPQ4	Gene names	Stk32a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32A (EC 2.7.11.1).

ERIC1_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.055232 (rank : 28)
Query Neighborhood Hits	125	Target Neighborhood Hits	364	Shared Neighborhood Hits	29
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

LEO1_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.059636 (rank : 19)
Query Neighborhood Hits	125	Target Neighborhood Hits	958	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.059835 (rank : 18)
Query Neighborhood Hits	125	Target Neighborhood Hits	946	Shared Neighborhood Hits	49
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

Hits sorted by NC score

RIOK2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	125	Target Neighborhood Hits	125	Shared Neighborhood Hits	125
SwissProt Accessions	Q9BVS4, Q9NUT0	Gene names	RIOK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

RIOK2_MOUSE
NC score	0.959589 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	125	Target Neighborhood Hits	82	Shared Neighborhood Hits	43
SwissProt Accessions	Q9CQS5, Q91XF3	Gene names	Riok2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

RIOK1_HUMAN
NC score	0.420495 (rank : 3)	θ value	9.59137e-10 (rank : 3)
Query Neighborhood Hits	125	Target Neighborhood Hits	86	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BRS2, Q8NDC8, Q96NV9	Gene names	RIOK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (RIO kinase 1).

RIOK3_MOUSE
NC score	0.352499 (rank : 4)	θ value	5.81887e-07 (rank : 4)
Query Neighborhood Hits	125	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DBU3, Q8CIC1	Gene names	Riok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3).

RIOK3_HUMAN
NC score	0.343546 (rank : 5)	θ value	2.21117e-06 (rank : 5)
Query Neighborhood Hits	125	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	O14730, Q8IXN9	Gene names	RIOK3, SUDD
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog).

HTSF1_MOUSE
NC score	0.144803 (rank : 6)	θ value	3.19293e-05 (rank : 6)
Query Neighborhood Hits	125	Target Neighborhood Hits	425	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

HTSF1_HUMAN
NC score	0.121501 (rank : 7)	θ value	0.00665767 (rank : 8)
Query Neighborhood Hits	125	Target Neighborhood Hits	408	Shared Neighborhood Hits	15
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

BMS1_HUMAN
NC score	0.107250 (rank : 8)	θ value	0.0193708 (rank : 10)
Query Neighborhood Hits	125	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q14692, Q86XJ9	Gene names	BMS1L, KIAA0187
Domain Architecture
Description	Ribosome biogenesis protein BMS1 homolog.

DMP1_MOUSE
NC score	0.080032 (rank : 9)	θ value	0.0961366 (rank : 12)
Query Neighborhood Hits	125	Target Neighborhood Hits	498	Shared Neighborhood Hits	33
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

DMP1_HUMAN
NC score	0.074942 (rank : 10)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	125	Target Neighborhood Hits	491	Shared Neighborhood Hits	33
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

YTDC1_HUMAN
NC score	0.073617 (rank : 11)	θ value	0.0961366 (rank : 13)
Query Neighborhood Hits	125	Target Neighborhood Hits	458	Shared Neighborhood Hits	30
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

NRK_HUMAN
NC score	0.071649 (rank : 12)	θ value	0.00102713 (rank : 7)
Query Neighborhood Hits	125	Target Neighborhood Hits	931	Shared Neighborhood Hits	58
SwissProt Accessions	Q7Z2Y5, Q32ND6, Q5H9K2, Q6ZMP2	Gene names	NRK
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1).

NRK_MOUSE
NC score	0.069207 (rank : 13)	θ value	0.0148317 (rank : 9)
Query Neighborhood Hits	125	Target Neighborhood Hits	899	Shared Neighborhood Hits	58
SwissProt Accessions	Q9R0G8, Q6NV55, Q8C9S9, Q9R0S4	Gene names	Nrk, Nesk
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1) (Nck-interacting kinase-like embryo specific kinase) (NIK-like embryo-specific kinase) (NESK).

PTMA_HUMAN
NC score	0.065043 (rank : 14)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	125	Target Neighborhood Hits	88	Shared Neighborhood Hits	10
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

RPGR1_MOUSE
NC score	0.064604 (rank : 15)	θ value	0.0252991 (rank : 11)
Query Neighborhood Hits	125	Target Neighborhood Hits	713	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

IWS1_HUMAN
NC score	0.064116 (rank : 16)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	125	Target Neighborhood Hits	1241	Shared Neighborhood Hits	53
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
NC score	0.063410 (rank : 17)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	125	Target Neighborhood Hits	1258	Shared Neighborhood Hits	53
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LEO1_MOUSE
NC score	0.059835 (rank : 18)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	125	Target Neighborhood Hits	946	Shared Neighborhood Hits	49
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LEO1_HUMAN
NC score	0.059636 (rank : 19)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	125	Target Neighborhood Hits	958	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

M4K3_HUMAN
NC score	0.058446 (rank : 20)	θ value	0.163984 (rank : 15)
Query Neighborhood Hits	125	Target Neighborhood Hits	857	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IVH8, Q8IVH7, Q9UDM5, Q9Y6R5	Gene names	MAP4K3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase-related protein kinase) (GLK).

MASTL_HUMAN
NC score	0.058362 (rank : 21)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	125	Target Neighborhood Hits	894	Shared Neighborhood Hits	55
SwissProt Accessions	Q96GX5, Q5T8D5, Q5T8D7, Q8NCD6, Q96SJ5	Gene names	MASTL, THC2
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

SRCH_HUMAN
NC score	0.058318 (rank : 22)	θ value	0.47712 (rank : 20)
Query Neighborhood Hits	125	Target Neighborhood Hits	225	Shared Neighborhood Hits	10
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

E2AK4_MOUSE
NC score	0.057642 (rank : 23)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	125	Target Neighborhood Hits	984	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QZ05, Q6GQT4, Q6ZPT5, Q8C5S0, Q8CIF5, Q9CT30, Q9CUV9, Q9ESB6, Q9ESB7, Q9ESB8	Gene names	Eif2ak4, Gcn2, Kiaa1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein) (mGCN2).

MASTL_MOUSE
NC score	0.057195 (rank : 24)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	125	Target Neighborhood Hits	862	Shared Neighborhood Hits	56
SwissProt Accessions	Q8C0P0, Q5RJW0, Q6NXX9, Q8BVF3, Q9CZH9, Q9D9V0	Gene names	Mastl
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

E2AK4_HUMAN
NC score	0.056358 (rank : 25)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	125	Target Neighborhood Hits	1012	Shared Neighborhood Hits	58
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).

KPCB_MOUSE
NC score	0.055943 (rank : 26)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	125	Target Neighborhood Hits	1117	Shared Neighborhood Hits	57
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_HUMAN
NC score	0.055800 (rank : 27)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	125	Target Neighborhood Hits	1121	Shared Neighborhood Hits	57
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

ERIC1_HUMAN
NC score	0.055232 (rank : 28)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	125	Target Neighborhood Hits	364	Shared Neighborhood Hits	29
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

KPCA_HUMAN
NC score	0.055062 (rank : 29)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	125	Target Neighborhood Hits	1070	Shared Neighborhood Hits	57
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

M4K2_MOUSE
NC score	0.054911 (rank : 30)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	125	Target Neighborhood Hits	843	Shared Neighborhood Hits	55
SwissProt Accessions	Q61161	Gene names	Map4k2, Rab8ip
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GCK) (Rab8-interacting protein).

KPCE_HUMAN
NC score	0.054415 (rank : 31)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	125	Target Neighborhood Hits	906	Shared Neighborhood Hits	58
SwissProt Accessions	Q02156, Q53SL4, Q53SM5, Q9UE81	Gene names	PRKCE, PKCE
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

KPCE_MOUSE
NC score	0.054167 (rank : 32)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	125	Target Neighborhood Hits	906	Shared Neighborhood Hits	57
SwissProt Accessions	P16054	Gene names	Prkce, Pkce, Pkcea
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

KPCG_HUMAN
NC score	0.053161 (rank : 33)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	125	Target Neighborhood Hits	1126	Shared Neighborhood Hits	57
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_MOUSE
NC score	0.053139 (rank : 34)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	125	Target Neighborhood Hits	1123	Shared Neighborhood Hits	57
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

M4K5_MOUSE
NC score	0.052907 (rank : 35)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	125	Target Neighborhood Hits	839	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BPM2, Q6PEQ2, Q8C3U5, Q8CGF3, Q99LM7, Q9CX73	Gene names	Map4k5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5).

KPCA_MOUSE
NC score	0.052900 (rank : 36)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	125	Target Neighborhood Hits	1067	Shared Neighborhood Hits	57
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

M4K5_HUMAN
NC score	0.052652 (rank : 37)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	125	Target Neighborhood Hits	845	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y4K4, Q8IYF6	Gene names	MAP4K5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5) (Kinase homologous to SPS1/STE20) (KHS).

M4K2_HUMAN
NC score	0.052455 (rank : 38)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	125	Target Neighborhood Hits	850	Shared Neighborhood Hits	55
SwissProt Accessions	Q12851	Gene names	MAP4K2, GCK, RAB8IP
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GC kinase) (Rab8-interacting protein) (B lymphocyte serine/threonine-protein kinase).

KPCT_HUMAN
NC score	0.052363 (rank : 39)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	125	Target Neighborhood Hits	897	Shared Neighborhood Hits	55
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

TF2AY_MOUSE
NC score	0.052056 (rank : 40)	θ value	0.47712 (rank : 21)
Query Neighborhood Hits	125	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4I4, Q99PM2, Q9DAF4	Gene names	Gtf2a1lf, Alf
Domain Architecture
Description	TFIIA-alpha and beta-like factor (General transcription factor II A, 1-like factor).

KPCD_HUMAN
NC score	0.051620 (rank : 41)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	125	Target Neighborhood Hits	900	Shared Neighborhood Hits	55
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

MAST4_HUMAN
NC score	0.051177 (rank : 42)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	125	Target Neighborhood Hits	1804	Shared Neighborhood Hits	69
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

KPCD_MOUSE
NC score	0.050967 (rank : 43)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	125	Target Neighborhood Hits	888	Shared Neighborhood Hits	55
SwissProt Accessions	P28867, Q91V85, Q9Z333	Gene names	Prkcd, Pkcd
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

CHK1_MOUSE
NC score	0.050735 (rank : 44)	θ value	0.365318 (rank : 17)
Query Neighborhood Hits	125	Target Neighborhood Hits	839	Shared Neighborhood Hits	55
SwissProt Accessions	O35280, O54925, Q8CI40, Q9D0N2	Gene names	Chek1, Chk1
Domain Architecture
Description	Serine/threonine-protein kinase Chk1 (EC 2.7.11.1).

KPCT_MOUSE
NC score	0.050693 (rank : 45)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	125	Target Neighborhood Hits	895	Shared Neighborhood Hits	55
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

MAST1_HUMAN
NC score	0.050185 (rank : 46)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	125	Target Neighborhood Hits	1146	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

KKCC2_MOUSE
NC score	0.050087 (rank : 47)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	125	Target Neighborhood Hits	855	Shared Neighborhood Hits	55
SwissProt Accessions	Q8C078, Q80TS0, Q8BXM8, Q8C0G3, Q8CH42, Q8QZT7	Gene names	Camkk2, Kiaa0787
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta).

KKCC2_HUMAN
NC score	0.050050 (rank : 48)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	125	Target Neighborhood Hits	852	Shared Neighborhood Hits	55
SwissProt Accessions	Q96RR4, O94883, Q8IUG2, Q8IUG3, Q8N3I4, Q8WY03, Q8WY04, Q8WY05, Q8WY06, Q96RP1, Q96RP2, Q96RR3, Q9BWE9, Q9UER3, Q9UES2, Q9Y5N2	Gene names	CAMKK2, CAMKKB, KIAA0787
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta).

MAST1_MOUSE
NC score	0.049977 (rank : 49)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	125	Target Neighborhood Hits	1123	Shared Neighborhood Hits	57
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST3_HUMAN
NC score	0.049519 (rank : 50)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	125	Target Neighborhood Hits	1128	Shared Neighborhood Hits	58
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

ST32B_HUMAN
NC score	0.049017 (rank : 51)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	125	Target Neighborhood Hits	830	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NY57, Q6UXH3, Q8IY14	Gene names	STK32B
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32B (EC 2.7.11.1) (YANK2).

ASPX_MOUSE
NC score	0.048788 (rank : 52)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	125	Target Neighborhood Hits	49	Shared Neighborhood Hits	6
SwissProt Accessions	P50289, Q9DAM6	Gene names	Acrv1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1) (MSA- 63).

ST32B_MOUSE
NC score	0.048706 (rank : 53)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	125	Target Neighborhood Hits	828	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JJX8, Q7TMD3, Q8C4E0	Gene names	Stk32b, Stk32
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32B (EC 2.7.11.1).

MAST2_HUMAN
NC score	0.048409 (rank : 54)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	125	Target Neighborhood Hits	1189	Shared Neighborhood Hits	61
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

KS6B2_MOUSE
NC score	0.048311 (rank : 55)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	125	Target Neighborhood Hits	871	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z1M4	Gene names	Rps6kb2
Domain Architecture
Description	Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2).

MAST2_MOUSE
NC score	0.047991 (rank : 56)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	125	Target Neighborhood Hits	1110	Shared Neighborhood Hits	59
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

ST32A_HUMAN
NC score	0.047497 (rank : 57)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	125	Target Neighborhood Hits	834	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WU08	Gene names	STK32A
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32A (EC 2.7.11.1) (YANK1).

TSSK4_MOUSE
NC score	0.047263 (rank : 58)	θ value	1.38821 (rank : 35)
Query Neighborhood Hits	125	Target Neighborhood Hits	840	Shared Neighborhood Hits	55
SwissProt Accessions	Q9D411	Gene names	Tssk4
Domain Architecture	No domain graphic available
Description	Testis-specific serine/threonine-protein kinase 4 (EC 2.7.11.1) (TSSK- 4) (Testis-specific kinase 4) (TSK-4).

EXOC2_MOUSE
NC score	0.046989 (rank : 59)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	125	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D4H1	Gene names	Exoc2, Sec5, Sec5l1
Domain Architecture
Description	Exocyst complex component 2 (Exocyst complex component Sec5).

HUNK_MOUSE
NC score	0.046898 (rank : 60)	θ value	1.81305 (rank : 38)
Query Neighborhood Hits	125	Target Neighborhood Hits	874	Shared Neighborhood Hits	55
SwissProt Accessions	O88866	Gene names	Hunk, Makv
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V).

HUNK_HUMAN
NC score	0.046398 (rank : 61)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	125	Target Neighborhood Hits	884	Shared Neighborhood Hits	55
SwissProt Accessions	P57058	Gene names	HUNK, MAKV
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19).

ST32A_MOUSE
NC score	0.046388 (rank : 62)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	125	Target Neighborhood Hits	833	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BGW6, Q7TPQ4	Gene names	Stk32a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32A (EC 2.7.11.1).

TTK_MOUSE
NC score	0.046166 (rank : 63)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	125	Target Neighborhood Hits	803	Shared Neighborhood Hits	56
SwissProt Accessions	P35761	Gene names	Ttk, Esk
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (ESK) (PYT).

CHK1_HUMAN
NC score	0.045545 (rank : 64)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	125	Target Neighborhood Hits	843	Shared Neighborhood Hits	54
SwissProt Accessions	O14757	Gene names	CHEK1, CHK1
Domain Architecture
Description	Serine/threonine-protein kinase Chk1 (EC 2.7.11.1).

TTK_HUMAN
NC score	0.045516 (rank : 65)	θ value	1.06291 (rank : 30)
Query Neighborhood Hits	125	Target Neighborhood Hits	816	Shared Neighborhood Hits	55
SwissProt Accessions	P33981	Gene names	TTK, MPS1L1
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT).

CD2L1_HUMAN
NC score	0.045507 (rank : 66)	θ value	0.365318 (rank : 16)
Query Neighborhood Hits	125	Target Neighborhood Hits	1467	Shared Neighborhood Hits	72
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

PAK7_MOUSE
NC score	0.045445 (rank : 67)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	125	Target Neighborhood Hits	875	Shared Neighborhood Hits	55
SwissProt Accessions	Q8C015, Q3TQJ7, Q6RWS7	Gene names	Pak7, Pak5
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (p21-activated kinase 5).

STK39_MOUSE
NC score	0.045250 (rank : 68)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	125	Target Neighborhood Hits	915	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z1W9, Q80W13	Gene names	Stk39, Spak
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39).

MP2K7_HUMAN
NC score	0.045063 (rank : 69)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	125	Target Neighborhood Hits	833	Shared Neighborhood Hits	54
SwissProt Accessions	O14733, O14648, O14816, O60452, O60453	Gene names	MAP2K7, JNKK2, MKK7, PRKMK7
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 7 (EC 2.7.12.2) (MAP kinase kinase 7) (MAPKK 7) (MAPK/ERK kinase 7) (JNK-activating kinase 2) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2).

CD2L2_HUMAN
NC score	0.044636 (rank : 70)	θ value	0.47712 (rank : 19)
Query Neighborhood Hits	125	Target Neighborhood Hits	1439	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

AP3B2_MOUSE
NC score	0.044256 (rank : 71)	θ value	0.163984 (rank : 14)
Query Neighborhood Hits	125	Target Neighborhood Hits	246	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

TAOK3_HUMAN
NC score	0.043705 (rank : 72)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	125	Target Neighborhood Hits	1494	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

CD2L1_MOUSE
NC score	0.042689 (rank : 73)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	125	Target Neighborhood Hits	1463	Shared Neighborhood Hits	71
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

EXOC2_HUMAN
NC score	0.040932 (rank : 74)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	125	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q96KP1, Q5JPC8, Q96AN6, Q9NUZ8, Q9UJM7	Gene names	EXOC2, SEC5, SEC5L1
Domain Architecture
Description	Exocyst complex component 2 (Exocyst complex component Sec5).

SCG1_HUMAN
NC score	0.039672 (rank : 75)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	125	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	P05060, Q9BQV6, Q9UJA6	Gene names	CHGB, SCG1
Domain Architecture
Description	Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB) [Contains: GAWK peptide; CCB peptide].

TRI44_HUMAN
NC score	0.039348 (rank : 76)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	125	Target Neighborhood Hits	393	Shared Neighborhood Hits	16
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

IF2P_HUMAN
NC score	0.039307 (rank : 77)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	125	Target Neighborhood Hits	889	Shared Neighborhood Hits	22
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

LAS1L_HUMAN
NC score	0.038834 (rank : 78)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	125	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4W2, Q5JXQ0, Q8TEN5, Q9H9V5	Gene names	LAS1L
Domain Architecture	No domain graphic available
Description	LAS1-like protein.

CDK7_MOUSE
NC score	0.037834 (rank : 79)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	125	Target Neighborhood Hits	835	Shared Neighborhood Hits	54
SwissProt Accessions	Q03147, Q99KK3	Gene names	Cdk7, Cdkn7, Crk4, Mo15, Mpk-7
Domain Architecture
Description	Cell division protein kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (CDK- activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinase) (CRK4).

CDK7_HUMAN
NC score	0.037670 (rank : 80)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	125	Target Neighborhood Hits	833	Shared Neighborhood Hits	54
SwissProt Accessions	P50613, Q9BS60, Q9UE19	Gene names	CDK7, MO15
Domain Architecture
Description	Cell division protein kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (CDK- activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1).

TTBK2_MOUSE
NC score	0.037359 (rank : 81)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	125	Target Neighborhood Hits	811	Shared Neighborhood Hits	58
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

AP3B1_HUMAN
NC score	0.037116 (rank : 82)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	125	Target Neighborhood Hits	283	Shared Neighborhood Hits	15
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

BASP_MOUSE
NC score	0.035963 (rank : 83)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	125	Target Neighborhood Hits	260	Shared Neighborhood Hits	14
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

TRI44_MOUSE
NC score	0.035390 (rank : 84)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	125	Target Neighborhood Hits	327	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TNNT3_MOUSE
NC score	0.033604 (rank : 85)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	125	Target Neighborhood Hits	317	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QZ47, O35575, O35576, O35577, O35578, O35579, O35580, O35581, O35582, O35583, O35584, O35585, P97456, Q99L89, Q9QZ46	Gene names	Tnnt3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT).

RP1L1_HUMAN
NC score	0.033393 (rank : 86)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	125	Target Neighborhood Hits	1072	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SSRP1_MOUSE
NC score	0.032311 (rank : 87)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	125	Target Neighborhood Hits	193	Shared Neighborhood Hits	7
SwissProt Accessions	Q08943, Q3U9Z2, Q3UJ75, Q4V9U4, Q8CGA6	Gene names	Ssrp1
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Structure-specific recognition protein 1) (Recombination signal sequence recognition protein 1) (T160).

TAI12_HUMAN
NC score	0.031695 (rank : 88)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	125	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H175	Gene names	TAIP12, C12orf22
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 12 (TAIP-12).

SSRP1_HUMAN
NC score	0.031264 (rank : 89)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	125	Target Neighborhood Hits	187	Shared Neighborhood Hits	7
SwissProt Accessions	Q08945, Q5BJG8	Gene names	SSRP1, FACT80
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (FACT 80 kDa subunit) (FACTp80) (Chromatin- specific transcription elongation factor 80 kDa subunit) (Structure- specific recognition protein 1) (hSSRP1) (Recombination signal sequence recognition protein 1) (T160).

TAI12_MOUSE
NC score	0.029108 (rank : 90)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	125	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGQ2, Q3UIH1	Gene names	Taip12
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 12 (TAIP-12).

PCLO_HUMAN
NC score	0.028661 (rank : 91)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	125	Target Neighborhood Hits	2046	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

GP158_MOUSE
NC score	0.028201 (rank : 92)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	125	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

BPTF_HUMAN
NC score	0.027824 (rank : 93)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	125	Target Neighborhood Hits	786	Shared Neighborhood Hits	28
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CJ078_HUMAN
NC score	0.026923 (rank : 94)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	125	Target Neighborhood Hits	61	Shared Neighborhood Hits	5
SwissProt Accessions	Q86XK3, Q5JT40, Q8WW47	Gene names	C10orf78
Domain Architecture	No domain graphic available
Description	Protein C10orf78.

TNNT3_HUMAN
NC score	0.026654 (rank : 95)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	125	Target Neighborhood Hits	327	Shared Neighborhood Hits	14
SwissProt Accessions	P45378, Q12975, Q12976, Q12977, Q12978, Q86TH6	Gene names	TNNT3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT) (Beta TnTF).

MAVS_MOUSE
NC score	0.025492 (rank : 96)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	125	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VCF0	Gene names	Mavs, Ips1, Visa
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif).

CF153_HUMAN
NC score	0.025160 (rank : 97)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	125	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	Q96EU6, Q9BRF6, Q9P0C8	Gene names	C6orf153
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf153.

CHD2_HUMAN
NC score	0.024580 (rank : 98)	θ value	0.62314 (rank : 22)
Query Neighborhood Hits	125	Target Neighborhood Hits	360	Shared Neighborhood Hits	14
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CO5_MOUSE
NC score	0.024462 (rank : 99)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	125	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P06684	Gene names	C5, Hc
Domain Architecture
Description	Complement C5 precursor (Hemolytic complement) [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

CF153_MOUSE
NC score	0.023993 (rank : 100)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	125	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UFY0, Q91X71	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf153 homolog.

PCLO_MOUSE
NC score	0.023391 (rank : 101)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	125	Target Neighborhood Hits	2275	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

NEST_HUMAN
NC score	0.023324 (rank : 102)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	125	Target Neighborhood Hits	1305	Shared Neighborhood Hits	36
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

NEB1_HUMAN
NC score	0.022957 (rank : 103)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	125	Target Neighborhood Hits	829	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

CHD4_MOUSE
NC score	0.020977 (rank : 104)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	125	Target Neighborhood Hits	408	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

MINT_MOUSE
NC score	0.019965 (rank : 105)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	125	Target Neighborhood Hits	1514	Shared Neighborhood Hits	37
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CHD4_HUMAN
NC score	0.019640 (rank : 106)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	125	Target Neighborhood Hits	365	Shared Neighborhood Hits	13
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

ACINU_MOUSE
NC score	0.019284 (rank : 107)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	125	Target Neighborhood Hits	712	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

VPS54_MOUSE
NC score	0.017216 (rank : 108)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	125	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SPW0, Q8BPB3, Q8CFZ7, Q8CHL5, Q8R3R4, Q8R3X1	Gene names	Vps54
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p homolog).

TFEB_MOUSE
NC score	0.015918 (rank : 109)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	125	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

GOGB1_HUMAN
NC score	0.015870 (rank : 110)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	125	Target Neighborhood Hits	2297	Shared Neighborhood Hits	44
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

LNP_HUMAN
NC score	0.015566 (rank : 111)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	125	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9C0E8, Q2M2V8, Q2YD99, Q658W8, Q8N5V9, Q96MS5	Gene names	LNP, KIAA1715
Domain Architecture	No domain graphic available
Description	Protein lunapark.

SMC3_HUMAN
NC score	0.014919 (rank : 112)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	125	Target Neighborhood Hits	1186	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

CP250_HUMAN
NC score	0.014866 (rank : 113)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	125	Target Neighborhood Hits	1805	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

SMC3_MOUSE
NC score	0.014754 (rank : 114)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	125	Target Neighborhood Hits	1187	Shared Neighborhood Hits	26
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

HNRPU_HUMAN
NC score	0.014361 (rank : 115)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	125	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q00839, O75507, Q96HY9	Gene names	HNRPU, SAFA, U21.1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein U (hnRNP U) (Scaffold attachment factor A) (SAF-A) (p120) (pp120).

AN32B_MOUSE
NC score	0.013764 (rank : 116)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	125	Target Neighborhood Hits	236	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EST5	Gene names	Anp32b, Pal31
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31).

IQEC3_MOUSE
NC score	0.013545 (rank : 117)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	125	Target Neighborhood Hits	274	Shared Neighborhood Hits	10
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

FBXW7_HUMAN
NC score	0.012333 (rank : 118)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	125	Target Neighborhood Hits	433	Shared Neighborhood Hits	8
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

MACF4_HUMAN
NC score	0.012209 (rank : 119)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	125	Target Neighborhood Hits	1321	Shared Neighborhood Hits	26
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

SM1L2_HUMAN
NC score	0.012067 (rank : 120)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	125	Target Neighborhood Hits	1019	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

NUMA1_HUMAN
NC score	0.011669 (rank : 121)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	125	Target Neighborhood Hits	1523	Shared Neighborhood Hits	26
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

NFM_MOUSE
NC score	0.009124 (rank : 122)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	125	Target Neighborhood Hits	1159	Shared Neighborhood Hits	28
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

ANK2_HUMAN
NC score	0.008764 (rank : 123)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	125	Target Neighborhood Hits	1615	Shared Neighborhood Hits	29
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

RBM28_HUMAN
NC score	0.008477 (rank : 124)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	125	Target Neighborhood Hits	307	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NW13, Q96CV3	Gene names	RBM28
Domain Architecture	No domain graphic available
Description	RNA-binding protein 28 (RNA-binding motif protein 28).

PLXB3_MOUSE
NC score	0.005109 (rank : 125)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	125	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QY40, Q80TH8	Gene names	Plxnb3, Kiaa1206, Plxn6
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor (Plexin-6).

HXC10_MOUSE
NC score	0.004453 (rank : 126)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	125	Target Neighborhood Hits	417	Shared Neighborhood Hits	14
SwissProt Accessions	P31257, P31312, Q7TMT7	Gene names	Hoxc10, Hox-3.6, Hoxc-10
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-C10 (Hox-3.6).

PTPRG_HUMAN
NC score	0.003355 (rank : 127)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	125	Target Neighborhood Hits	231	Shared Neighborhood Hits	6
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

CCKAR_MOUSE
NC score	0.001141 (rank : 128)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	125	Target Neighborhood Hits	931	Shared Neighborhood Hits	2
SwissProt Accessions	O08786, Q8VCC7, Q9DBV6	Gene names	Cckar
Domain Architecture
Description	Cholecystokinin type A receptor (CCK-A receptor) (CCK-AR) (Cholecystokinin-1 receptor) (CCK1-R).