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Network neighborhood for query Sequence : PYR5_MOUSE

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PYR5_MOUSE
SwissProt Accessions	P13439, Q99L26	Gene names	Umps
Domain Architecture
Description	Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (EC 2.4.2.10) (OPRTase); Orotidine 5'- phosphate decarboxylase (EC 4.1.1.23) (OMPdecase)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PYR5_HUMAN
θ value	0 (rank : 1)	NC score	0.997319 (rank : 2)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P11172, O00758, O00759, O00760, Q16862, Q9H3Q2, Q9UG49	Gene names	UMPS
Domain Architecture
Description	Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (EC 2.4.2.10) (OPRTase); Orotidine 5'- phosphate decarboxylase (EC 4.1.1.23) (OMPdecase)].

PYR5_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P13439, Q99L26	Gene names	Umps
Domain Architecture
Description	Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (EC 2.4.2.10) (OPRTase); Orotidine 5'- phosphate decarboxylase (EC 4.1.1.23) (OMPdecase)].

SPAST_HUMAN
θ value	0.62314 (rank : 3)	NC score	0.020515 (rank : 8)
Query Neighborhood Hits	8	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

NCOA5_HUMAN
θ value	3.0926 (rank : 4)	NC score	0.043688 (rank : 3)
Query Neighborhood Hits	8	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCD5, Q6HA99, Q9H1F2, Q9H2T2, Q9H4Y9	Gene names	NCOA5, KIAA1637
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA).

AXUD1_MOUSE
θ value	4.03905 (rank : 5)	NC score	0.020739 (rank : 7)
Query Neighborhood Hits	8	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	P59054	Gene names	Axud1, Taip3
Domain Architecture	No domain graphic available
Description	Axin-1 up-regulated gene 1 protein (TGF-beta-induced apoptosis protein 3) (TAIP-3).

FA53B_HUMAN
θ value	4.03905 (rank : 6)	NC score	0.027499 (rank : 4)
Query Neighborhood Hits	8	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q14153, Q8N5S6	Gene names	FAM53B, KIAA0140
Domain Architecture	No domain graphic available
Description	Protein FAM53B.

GDIR_HUMAN
θ value	5.27518 (rank : 7)	NC score	0.023977 (rank : 5)
Query Neighborhood Hits	8	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	P52565	Gene names	ARHGDIA, GDIA1
Domain Architecture
Description	Rho GDP-dissociation inhibitor 1 (Rho GDI 1) (Rho-GDI alpha).

GDIR_MOUSE
θ value	6.88961 (rank : 8)	NC score	0.022401 (rank : 6)
Query Neighborhood Hits	8	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PT1, Q99KC4	Gene names	Arhgdia, C87222, Gdi1
Domain Architecture
Description	Rho GDP-dissociation inhibitor 1 (Rho GDI 1) (Rho-GDI alpha) (GDI-1).

Hits sorted by NC score

PYR5_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P13439, Q99L26	Gene names	Umps
Domain Architecture
Description	Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (EC 2.4.2.10) (OPRTase); Orotidine 5'- phosphate decarboxylase (EC 4.1.1.23) (OMPdecase)].

PYR5_HUMAN
NC score	0.997319 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P11172, O00758, O00759, O00760, Q16862, Q9H3Q2, Q9UG49	Gene names	UMPS
Domain Architecture
Description	Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (EC 2.4.2.10) (OPRTase); Orotidine 5'- phosphate decarboxylase (EC 4.1.1.23) (OMPdecase)].

NCOA5_HUMAN
NC score	0.043688 (rank : 3)	θ value	3.0926 (rank : 4)
Query Neighborhood Hits	8	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCD5, Q6HA99, Q9H1F2, Q9H2T2, Q9H4Y9	Gene names	NCOA5, KIAA1637
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA).

FA53B_HUMAN
NC score	0.027499 (rank : 4)	θ value	4.03905 (rank : 6)
Query Neighborhood Hits	8	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q14153, Q8N5S6	Gene names	FAM53B, KIAA0140
Domain Architecture	No domain graphic available
Description	Protein FAM53B.

GDIR_HUMAN
NC score	0.023977 (rank : 5)	θ value	5.27518 (rank : 7)
Query Neighborhood Hits	8	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	P52565	Gene names	ARHGDIA, GDIA1
Domain Architecture
Description	Rho GDP-dissociation inhibitor 1 (Rho GDI 1) (Rho-GDI alpha).

GDIR_MOUSE
NC score	0.022401 (rank : 6)	θ value	6.88961 (rank : 8)
Query Neighborhood Hits	8	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PT1, Q99KC4	Gene names	Arhgdia, C87222, Gdi1
Domain Architecture
Description	Rho GDP-dissociation inhibitor 1 (Rho GDI 1) (Rho-GDI alpha) (GDI-1).

AXUD1_MOUSE
NC score	0.020739 (rank : 7)	θ value	4.03905 (rank : 5)
Query Neighborhood Hits	8	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	P59054	Gene names	Axud1, Taip3
Domain Architecture	No domain graphic available
Description	Axin-1 up-regulated gene 1 protein (TGF-beta-induced apoptosis protein 3) (TAIP-3).

SPAST_HUMAN
NC score	0.020515 (rank : 8)	θ value	0.62314 (rank : 3)
Query Neighborhood Hits	8	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.