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Network neighborhood for query Sequence : GDIR_HUMAN

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GDIR_HUMAN
SwissProt Accessions	P52565	Gene names	ARHGDIA, GDIA1
Domain Architecture
Description	Rho GDP-dissociation inhibitor 1 (Rho GDI 1) (Rho-GDI alpha).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GDIR_HUMAN
θ value	3.1986e-114 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	P52565	Gene names	ARHGDIA, GDIA1
Domain Architecture
Description	Rho GDP-dissociation inhibitor 1 (Rho GDI 1) (Rho-GDI alpha).

GDIR_MOUSE
θ value	1.13764e-111 (rank : 2)	NC score	0.998689 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	13
SwissProt Accessions	Q99PT1, Q99KC4	Gene names	Arhgdia, C87222, Gdi1
Domain Architecture
Description	Rho GDP-dissociation inhibitor 1 (Rho GDI 1) (Rho-GDI alpha) (GDI-1).

GDIS_MOUSE
θ value	2.82823e-78 (rank : 3)	NC score	0.992211 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q61599, Q3TEB3	Gene names	Arhgdib, Gdid4
Domain Architecture
Description	Rho GDP-dissociation inhibitor 2 (Rho GDI 2) (Rho-GDI beta) (D4).

GDIS_HUMAN
θ value	4.08394e-77 (rank : 4)	NC score	0.992739 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	P52566	Gene names	ARHGDIB, GDID4
Domain Architecture
Description	Rho GDP-dissociation inhibitor 2 (Rho GDI 2) (Rho-GDI beta) (Ly-GDI).

GDIT_HUMAN
θ value	1.04338e-64 (rank : 5)	NC score	0.985054 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q99819, Q4TT69, Q96S29	Gene names	ARHGDIG
Domain Architecture
Description	Rho GDP-dissociation inhibitor 3 (Rho GDI 3) (Rho-GDI gamma).

GDIT_MOUSE
θ value	8.26713e-62 (rank : 6)	NC score	0.983592 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q62160	Gene names	Arhgdig, Gdi5
Domain Architecture
Description	Rho GDP-dissociation inhibitor 3 (Rho GDI 3) (Rho-GDI gamma) (Rho- GDI2).

DC1I1_HUMAN
θ value	1.38821 (rank : 7)	NC score	0.037079 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	183	Shared Neighborhood Hits	4
SwissProt Accessions	O14576, Q9Y2X1	Gene names	DYNC1I1, DNCI1, DNCIC1
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 1 (Dynein intermediate chain 1, cytosolic) (DH IC-1) (Cytoplasmic dynein intermediate chain 1).

DC1I1_MOUSE
θ value	1.38821 (rank : 8)	NC score	0.037187 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	206	Shared Neighborhood Hits	4
SwissProt Accessions	O88485, O88486	Gene names	Dync1i1, Dnci1, Dncic1
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 1 (Dynein intermediate chain 1, cytosolic) (DH IC-1) (Cytoplasmic dynein intermediate chain 1).

AP3M2_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.027481 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	P53677	Gene names	AP3M2
Domain Architecture
Description	AP-3 complex subunit mu-2 (Adapter-related protein complex 3 mu-2 subunit) (Clathrin coat assembly protein AP47 homolog 2) (Clathrin coat-associated protein AP47 homolog 2) (Golgi adaptor AP-1 47 kDa protein homolog 2) (HA1 47 kDa subunit homolog 2) (Clathrin assembly protein assembly protein complex 1 medium chain homolog 2) (P47B).

RB6I2_HUMAN
θ value	4.03905 (rank : 10)	NC score	0.006854 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	1584	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RB6I2_MOUSE
θ value	4.03905 (rank : 11)	NC score	0.007454 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	1433	Shared Neighborhood Hits	4
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

CCDC4_HUMAN
θ value	5.27518 (rank : 12)	NC score	0.032772 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZU67, Q58A26, Q58A27	Gene names	CCDC4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 4.

PYR5_MOUSE
θ value	5.27518 (rank : 13)	NC score	0.023977 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P13439, Q99L26	Gene names	Umps
Domain Architecture
Description	Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (EC 2.4.2.10) (OPRTase); Orotidine 5'- phosphate decarboxylase (EC 4.1.1.23) (OMPdecase)].

SSFA2_MOUSE
θ value	5.27518 (rank : 14)	NC score	0.020332 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q922B9, Q8VEF7	Gene names	Ssfa2
Domain Architecture	No domain graphic available
Description	Sperm-specific antigen 2.

AP3M1_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.018459 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2T2	Gene names	AP3M1
Domain Architecture
Description	AP-3 complex subunit mu-1 (Adapter-related protein complex 3 mu-1 subunit) (Mu-adaptin 3A) (AP-3 adapter complex mu3A subunit).

AP3M1_MOUSE
θ value	8.99809 (rank : 16)	NC score	0.018470 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JKC8, Q5BKQ6	Gene names	Ap3m1
Domain Architecture
Description	AP-3 complex subunit mu-1 (Adapter-related protein complex 3 mu-1 subunit) (Mu-adaptin 3A) (AP-3 adapter complex mu3A subunit).

Hits sorted by NC score

GDIR_HUMAN
NC score	0.999962 (rank : 1)	θ value	3.1986e-114 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	P52565	Gene names	ARHGDIA, GDIA1
Domain Architecture
Description	Rho GDP-dissociation inhibitor 1 (Rho GDI 1) (Rho-GDI alpha).

GDIR_MOUSE
NC score	0.998689 (rank : 2)	θ value	1.13764e-111 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	13
SwissProt Accessions	Q99PT1, Q99KC4	Gene names	Arhgdia, C87222, Gdi1
Domain Architecture
Description	Rho GDP-dissociation inhibitor 1 (Rho GDI 1) (Rho-GDI alpha) (GDI-1).

GDIS_HUMAN
NC score	0.992739 (rank : 3)	θ value	4.08394e-77 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	P52566	Gene names	ARHGDIB, GDID4
Domain Architecture
Description	Rho GDP-dissociation inhibitor 2 (Rho GDI 2) (Rho-GDI beta) (Ly-GDI).

GDIS_MOUSE
NC score	0.992211 (rank : 4)	θ value	2.82823e-78 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q61599, Q3TEB3	Gene names	Arhgdib, Gdid4
Domain Architecture
Description	Rho GDP-dissociation inhibitor 2 (Rho GDI 2) (Rho-GDI beta) (D4).

GDIT_HUMAN
NC score	0.985054 (rank : 5)	θ value	1.04338e-64 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q99819, Q4TT69, Q96S29	Gene names	ARHGDIG
Domain Architecture
Description	Rho GDP-dissociation inhibitor 3 (Rho GDI 3) (Rho-GDI gamma).

GDIT_MOUSE
NC score	0.983592 (rank : 6)	θ value	8.26713e-62 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q62160	Gene names	Arhgdig, Gdi5
Domain Architecture
Description	Rho GDP-dissociation inhibitor 3 (Rho GDI 3) (Rho-GDI gamma) (Rho- GDI2).

DC1I1_MOUSE
NC score	0.037187 (rank : 7)	θ value	1.38821 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	206	Shared Neighborhood Hits	4
SwissProt Accessions	O88485, O88486	Gene names	Dync1i1, Dnci1, Dncic1
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 1 (Dynein intermediate chain 1, cytosolic) (DH IC-1) (Cytoplasmic dynein intermediate chain 1).

DC1I1_HUMAN
NC score	0.037079 (rank : 8)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	183	Shared Neighborhood Hits	4
SwissProt Accessions	O14576, Q9Y2X1	Gene names	DYNC1I1, DNCI1, DNCIC1
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 1 (Dynein intermediate chain 1, cytosolic) (DH IC-1) (Cytoplasmic dynein intermediate chain 1).

CCDC4_HUMAN
NC score	0.032772 (rank : 9)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZU67, Q58A26, Q58A27	Gene names	CCDC4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 4.

AP3M2_HUMAN
NC score	0.027481 (rank : 10)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	P53677	Gene names	AP3M2
Domain Architecture
Description	AP-3 complex subunit mu-2 (Adapter-related protein complex 3 mu-2 subunit) (Clathrin coat assembly protein AP47 homolog 2) (Clathrin coat-associated protein AP47 homolog 2) (Golgi adaptor AP-1 47 kDa protein homolog 2) (HA1 47 kDa subunit homolog 2) (Clathrin assembly protein assembly protein complex 1 medium chain homolog 2) (P47B).

PYR5_MOUSE
NC score	0.023977 (rank : 11)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P13439, Q99L26	Gene names	Umps
Domain Architecture
Description	Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (EC 2.4.2.10) (OPRTase); Orotidine 5'- phosphate decarboxylase (EC 4.1.1.23) (OMPdecase)].

SSFA2_MOUSE
NC score	0.020332 (rank : 12)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q922B9, Q8VEF7	Gene names	Ssfa2
Domain Architecture	No domain graphic available
Description	Sperm-specific antigen 2.

AP3M1_MOUSE
NC score	0.018470 (rank : 13)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JKC8, Q5BKQ6	Gene names	Ap3m1
Domain Architecture
Description	AP-3 complex subunit mu-1 (Adapter-related protein complex 3 mu-1 subunit) (Mu-adaptin 3A) (AP-3 adapter complex mu3A subunit).

AP3M1_HUMAN
NC score	0.018459 (rank : 14)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2T2	Gene names	AP3M1
Domain Architecture
Description	AP-3 complex subunit mu-1 (Adapter-related protein complex 3 mu-1 subunit) (Mu-adaptin 3A) (AP-3 adapter complex mu3A subunit).

RB6I2_MOUSE
NC score	0.007454 (rank : 15)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	1433	Shared Neighborhood Hits	4
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RB6I2_HUMAN
NC score	0.006854 (rank : 16)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	1584	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).