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Network neighborhood for query Sequence : FA53B_HUMAN

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FA53B_HUMAN
SwissProt Accessions	Q14153, Q8N5S6	Gene names	FAM53B, KIAA0140
Domain Architecture	No domain graphic available
Description	Protein FAM53B.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FA53B_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	Q14153, Q8N5S6	Gene names	FAM53B, KIAA0140
Domain Architecture	No domain graphic available
Description	Protein FAM53B.

FA53B_MOUSE
θ value	0 (rank : 2)	NC score	0.987711 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	29	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BGR5, Q3UGW1, Q8BI13	Gene names	Fam53b
Domain Architecture	No domain graphic available
Description	Protein FAM53B.

FA53C_HUMAN
θ value	2.28291e-11 (rank : 3)	NC score	0.530856 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYF3	Gene names	FAM53C, C5orf6
Domain Architecture	No domain graphic available
Description	Protein FAM53C.

FA53C_MOUSE
θ value	4.30538e-10 (rank : 4)	NC score	0.516439 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	40	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BXQ8, Q3U4J2	Gene names	Fam53c
Domain Architecture	No domain graphic available
Description	Protein FAM53C.

ATS13_MOUSE
θ value	0.813845 (rank : 5)	NC score	0.025730 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	227	Shared Neighborhood Hits	4
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

SPAG4_HUMAN
θ value	1.38821 (rank : 6)	NC score	0.030398 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NPE6, O43648	Gene names	SPAG4
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 4 protein (Outer dense fiber-associated protein SPAG4).

LIMD1_MOUSE
θ value	1.81305 (rank : 7)	NC score	0.023908 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	291	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

K1802_MOUSE
θ value	2.36792 (rank : 8)	NC score	0.023875 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	1596	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MAST1_HUMAN
θ value	3.0926 (rank : 9)	NC score	0.004283 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	1146	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

SSPO_MOUSE
θ value	3.0926 (rank : 10)	NC score	0.020000 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	800	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TRBM_HUMAN
θ value	3.0926 (rank : 11)	NC score	0.012594 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	339	Shared Neighborhood Hits	6
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

AN13D_MOUSE
θ value	4.03905 (rank : 12)	NC score	0.021023 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PD24	Gene names	Ankrd13d
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

GP178_HUMAN
θ value	4.03905 (rank : 13)	NC score	0.037291 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P2C4, Q5VTU1	Gene names	GPR178, KIAA1423
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR178.

PYR5_MOUSE
θ value	4.03905 (rank : 14)	NC score	0.027499 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	P13439, Q99L26	Gene names	Umps
Domain Architecture
Description	Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (EC 2.4.2.10) (OPRTase); Orotidine 5'- phosphate decarboxylase (EC 4.1.1.23) (OMPdecase)].

SORL_HUMAN
θ value	4.03905 (rank : 15)	NC score	0.021173 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	440	Shared Neighborhood Hits	7
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

PRR11_MOUSE
θ value	5.27518 (rank : 16)	NC score	0.026767 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BHE0, Q3V3H1	Gene names	Prr11
Domain Architecture	No domain graphic available
Description	Proline-rich protein 11.

RECQ5_HUMAN
θ value	5.27518 (rank : 17)	NC score	0.032803 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	390	Shared Neighborhood Hits	5
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

ABCBB_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.006164 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	O95342, Q9UNB2	Gene names	ABCB11, BSEP
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11).

RFIP3_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.007999 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	1055	Shared Neighborhood Hits	3
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

SORL_MOUSE
θ value	6.88961 (rank : 20)	NC score	0.016667 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	439	Shared Neighborhood Hits	6
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

EPS8_MOUSE
θ value	8.99809 (rank : 21)	NC score	0.009200 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	157	Shared Neighborhood Hits	2
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

LRP1_HUMAN
θ value	8.99809 (rank : 22)	NC score	0.010508 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	617	Shared Neighborhood Hits	6
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

MAST3_HUMAN
θ value	8.99809 (rank : 23)	NC score	0.002964 (rank : 25)
Query Neighborhood Hits	24	Target Neighborhood Hits	1128	Shared Neighborhood Hits	4
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

ZFYV9_HUMAN
θ value	8.99809 (rank : 24)	NC score	0.010540 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

NICE1_HUMAN
θ value	θ > 10 (rank : 25)	NC score	0.105746 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	12	Shared Neighborhood Hits	1
SwissProt Accessions	Q9UGL9	Gene names	NICE1, C1orf42
Domain Architecture	No domain graphic available
Description	Protein NICE-1.

Hits sorted by NC score

FA53B_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	Q14153, Q8N5S6	Gene names	FAM53B, KIAA0140
Domain Architecture	No domain graphic available
Description	Protein FAM53B.

FA53B_MOUSE
NC score	0.987711 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	29	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BGR5, Q3UGW1, Q8BI13	Gene names	Fam53b
Domain Architecture	No domain graphic available
Description	Protein FAM53B.

FA53C_HUMAN
NC score	0.530856 (rank : 3)	θ value	2.28291e-11 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYF3	Gene names	FAM53C, C5orf6
Domain Architecture	No domain graphic available
Description	Protein FAM53C.

FA53C_MOUSE
NC score	0.516439 (rank : 4)	θ value	4.30538e-10 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	40	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BXQ8, Q3U4J2	Gene names	Fam53c
Domain Architecture	No domain graphic available
Description	Protein FAM53C.

NICE1_HUMAN
NC score	0.105746 (rank : 5)	θ value	θ > 10 (rank : 25)
Query Neighborhood Hits	24	Target Neighborhood Hits	12	Shared Neighborhood Hits	1
SwissProt Accessions	Q9UGL9	Gene names	NICE1, C1orf42
Domain Architecture	No domain graphic available
Description	Protein NICE-1.

GP178_HUMAN
NC score	0.037291 (rank : 6)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P2C4, Q5VTU1	Gene names	GPR178, KIAA1423
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR178.

RECQ5_HUMAN
NC score	0.032803 (rank : 7)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	390	Shared Neighborhood Hits	5
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

SPAG4_HUMAN
NC score	0.030398 (rank : 8)	θ value	1.38821 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NPE6, O43648	Gene names	SPAG4
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 4 protein (Outer dense fiber-associated protein SPAG4).

PYR5_MOUSE
NC score	0.027499 (rank : 9)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	P13439, Q99L26	Gene names	Umps
Domain Architecture
Description	Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (EC 2.4.2.10) (OPRTase); Orotidine 5'- phosphate decarboxylase (EC 4.1.1.23) (OMPdecase)].

PRR11_MOUSE
NC score	0.026767 (rank : 10)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BHE0, Q3V3H1	Gene names	Prr11
Domain Architecture	No domain graphic available
Description	Proline-rich protein 11.

ATS13_MOUSE
NC score	0.025730 (rank : 11)	θ value	0.813845 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	227	Shared Neighborhood Hits	4
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

LIMD1_MOUSE
NC score	0.023908 (rank : 12)	θ value	1.81305 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	291	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

K1802_MOUSE
NC score	0.023875 (rank : 13)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	1596	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

SORL_HUMAN
NC score	0.021173 (rank : 14)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	440	Shared Neighborhood Hits	7
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

AN13D_MOUSE
NC score	0.021023 (rank : 15)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PD24	Gene names	Ankrd13d
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

SSPO_MOUSE
NC score	0.020000 (rank : 16)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	800	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

SORL_MOUSE
NC score	0.016667 (rank : 17)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	439	Shared Neighborhood Hits	6
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

TRBM_HUMAN
NC score	0.012594 (rank : 18)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	339	Shared Neighborhood Hits	6
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

ZFYV9_HUMAN
NC score	0.010540 (rank : 19)	θ value	8.99809 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

LRP1_HUMAN
NC score	0.010508 (rank : 20)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	617	Shared Neighborhood Hits	6
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

EPS8_MOUSE
NC score	0.009200 (rank : 21)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	157	Shared Neighborhood Hits	2
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

RFIP3_HUMAN
NC score	0.007999 (rank : 22)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	1055	Shared Neighborhood Hits	3
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

ABCBB_HUMAN
NC score	0.006164 (rank : 23)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	O95342, Q9UNB2	Gene names	ABCB11, BSEP
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11).

MAST1_HUMAN
NC score	0.004283 (rank : 24)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	1146	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST3_HUMAN
NC score	0.002964 (rank : 25)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	1128	Shared Neighborhood Hits	4
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).