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Network neighborhood for query Sequence : PRR10_HUMAN

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PRR10_HUMAN
SwissProt Accessions	Q8N7Y1	Gene names	PRR10
Domain Architecture	No domain graphic available
Description	Proline-rich protein 10.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PRR10_HUMAN
θ value	4.7686e-118 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N7Y1	Gene names	PRR10
Domain Architecture	No domain graphic available
Description	Proline-rich protein 10.

TAF4_HUMAN
θ value	0.0563607 (rank : 2)	NC score	0.101920 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	687	Shared Neighborhood Hits	6
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

MAST1_HUMAN
θ value	0.163984 (rank : 3)	NC score	0.017903 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	1146	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

GRB7_HUMAN
θ value	0.47712 (rank : 4)	NC score	0.046099 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	156	Shared Neighborhood Hits	2
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

DMBT1_HUMAN
θ value	0.62314 (rank : 5)	NC score	0.032092 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	152	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

CENG1_HUMAN
θ value	1.81305 (rank : 6)	NC score	0.031855 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	544	Shared Neighborhood Hits	3
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

TYK2_MOUSE
θ value	1.81305 (rank : 7)	NC score	0.010968 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	850	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

CK035_HUMAN
θ value	3.0926 (rank : 8)	NC score	0.049940 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	149	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IXW0	Gene names	C11orf35
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf35.

K1949_MOUSE
θ value	3.0926 (rank : 9)	NC score	0.048354 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	134	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BQ30, Q3UDS6, Q8CEY9, Q8R3D8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1949 homolog.

PCLO_MOUSE
θ value	3.0926 (rank : 10)	NC score	0.023404 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	2275	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

FBLN2_MOUSE
θ value	4.03905 (rank : 11)	NC score	0.012460 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	505	Shared Neighborhood Hits	5
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

HXD9_HUMAN
θ value	4.03905 (rank : 12)	NC score	0.012970 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	352	Shared Neighborhood Hits	3
SwissProt Accessions	P28356	Gene names	HOXD9, HOX4C
Domain Architecture
Description	Homeobox protein Hox-D9 (Hox-4C) (Hox-5.2).

PSL1_HUMAN
θ value	4.03905 (rank : 13)	NC score	0.032809 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	650	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

CENG1_MOUSE
θ value	5.27518 (rank : 14)	NC score	0.028491 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	531	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

K2027_HUMAN
θ value	5.27518 (rank : 15)	NC score	0.034595 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	194	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

NBR1_MOUSE
θ value	5.27518 (rank : 16)	NC score	0.036220 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	P97432, Q9JIH9	Gene names	Nbr1, M17s2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2).

MDC1_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.022723 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	1446	Shared Neighborhood Hits	7
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

CLD19_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.009767 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N6F1, Q8N8X0	Gene names	CLDN19
Domain Architecture
Description	Claudin-19.

HXA13_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.010129 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	351	Shared Neighborhood Hits	3
SwissProt Accessions	Q62424	Gene names	Hoxa13, Hox-1.10
Domain Architecture
Description	Homeobox protein Hox-A13 (Hox-1.10).

SREC2_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.009956 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	645	Shared Neighborhood Hits	7
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

Hits sorted by NC score

PRR10_HUMAN
NC score	0.999962 (rank : 1)	θ value	4.7686e-118 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N7Y1	Gene names	PRR10
Domain Architecture	No domain graphic available
Description	Proline-rich protein 10.

TAF4_HUMAN
NC score	0.101920 (rank : 2)	θ value	0.0563607 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	687	Shared Neighborhood Hits	6
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

CK035_HUMAN
NC score	0.049940 (rank : 3)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	149	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IXW0	Gene names	C11orf35
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf35.

K1949_MOUSE
NC score	0.048354 (rank : 4)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	134	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BQ30, Q3UDS6, Q8CEY9, Q8R3D8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1949 homolog.

GRB7_HUMAN
NC score	0.046099 (rank : 5)	θ value	0.47712 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	156	Shared Neighborhood Hits	2
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

NBR1_MOUSE
NC score	0.036220 (rank : 6)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	P97432, Q9JIH9	Gene names	Nbr1, M17s2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2).

K2027_HUMAN
NC score	0.034595 (rank : 7)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	194	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

PSL1_HUMAN
NC score	0.032809 (rank : 8)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	650	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

DMBT1_HUMAN
NC score	0.032092 (rank : 9)	θ value	0.62314 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	152	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

CENG1_HUMAN
NC score	0.031855 (rank : 10)	θ value	1.81305 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	544	Shared Neighborhood Hits	3
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG1_MOUSE
NC score	0.028491 (rank : 11)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	531	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

PCLO_MOUSE
NC score	0.023404 (rank : 12)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	2275	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MDC1_HUMAN
NC score	0.022723 (rank : 13)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	1446	Shared Neighborhood Hits	7
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MAST1_HUMAN
NC score	0.017903 (rank : 14)	θ value	0.163984 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	1146	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

HXD9_HUMAN
NC score	0.012970 (rank : 15)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	352	Shared Neighborhood Hits	3
SwissProt Accessions	P28356	Gene names	HOXD9, HOX4C
Domain Architecture
Description	Homeobox protein Hox-D9 (Hox-4C) (Hox-5.2).

FBLN2_MOUSE
NC score	0.012460 (rank : 16)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	505	Shared Neighborhood Hits	5
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

TYK2_MOUSE
NC score	0.010968 (rank : 17)	θ value	1.81305 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	850	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

HXA13_MOUSE
NC score	0.010129 (rank : 18)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	351	Shared Neighborhood Hits	3
SwissProt Accessions	Q62424	Gene names	Hoxa13, Hox-1.10
Domain Architecture
Description	Homeobox protein Hox-A13 (Hox-1.10).

SREC2_HUMAN
NC score	0.009956 (rank : 19)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	645	Shared Neighborhood Hits	7
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

CLD19_HUMAN
NC score	0.009767 (rank : 20)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N6F1, Q8N8X0	Gene names	CLDN19
Domain Architecture
Description	Claudin-19.