Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : PORIM_HUMAN

For an explanation of this page, click here

PORIM_HUMAN
SwissProt Accessions	Q8N131, Q8IWS2, Q96QV2	Gene names	TMEM123, KCT3
Domain Architecture	No domain graphic available
Description	Porimin precursor (Transmembrane protein 123) (Pro-oncosis receptor inducing membrane injury) (Keratinocytes-associated transmembrane protein 3) (KCT-3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PORIM_HUMAN
θ value	2.3998e-69 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N131, Q8IWS2, Q96QV2	Gene names	TMEM123, KCT3
Domain Architecture	No domain graphic available
Description	Porimin precursor (Transmembrane protein 123) (Pro-oncosis receptor inducing membrane injury) (Keratinocytes-associated transmembrane protein 3) (KCT-3).

PORIM_MOUSE
θ value	6.84181e-24 (rank : 2)	NC score	0.802247 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	43	Shared Neighborhood Hits	8
SwissProt Accessions	Q91Z22, Q3T9F6, Q3TLL2, Q3U1R6, Q8CEX4	Gene names	Tmem123
Domain Architecture	No domain graphic available
Description	Porimin precursor (Transmembrane protein 123).

SMAD4_MOUSE
θ value	0.0113563 (rank : 3)	NC score	0.096395 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	101	Shared Neighborhood Hits	6
SwissProt Accessions	P97471, Q9CW56	Gene names	Smad4, Dpc4, Madh4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4 homolog) (Smad4).

SP3_MOUSE
θ value	0.0148317 (rank : 4)	NC score	0.038508 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	731	Shared Neighborhood Hits	4
SwissProt Accessions	O70494, Q68FF2, Q8CF64, Q8K378	Gene names	Sp3
Domain Architecture	No domain graphic available
Description	Transcription factor Sp3.

SP3_HUMAN
θ value	0.0431538 (rank : 5)	NC score	0.037000 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	737	Shared Neighborhood Hits	4
SwissProt Accessions	Q02447, Q8TD56, Q9BQR1	Gene names	SP3
Domain Architecture
Description	Transcription factor Sp3 (SPR-2).

MUCEN_MOUSE
θ value	0.21417 (rank : 6)	NC score	0.150873 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R0H2, Q78KL2, Q9DCN9, Q9ULC1, Q9Z2I1	Gene names	Emcn, Muc14
Domain Architecture	No domain graphic available
Description	Endomucin precursor (Endomucin-1/2).

GP112_HUMAN
θ value	0.279714 (rank : 7)	NC score	0.066979 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	441	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

NFRKB_MOUSE
θ value	0.365318 (rank : 8)	NC score	0.084312 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	393	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

ANGP1_MOUSE
θ value	0.62314 (rank : 9)	NC score	0.026888 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	252	Shared Neighborhood Hits	2
SwissProt Accessions	O08538	Gene names	Angpt1, Agpt
Domain Architecture
Description	Angiopoietin-1 precursor (ANG-1).

MUC5B_HUMAN
θ value	1.06291 (rank : 10)	NC score	0.092944 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	1020	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

SON_HUMAN
θ value	1.06291 (rank : 11)	NC score	0.044239 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	1568	Shared Neighborhood Hits	14
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

M3K5_HUMAN
θ value	1.38821 (rank : 12)	NC score	0.009194 (rank : 39)
Query Neighborhood Hits	34	Target Neighborhood Hits	868	Shared Neighborhood Hits	3
SwissProt Accessions	Q99683, Q5THN3, Q99461	Gene names	MAP3K5, ASK1, MAPKKK5, MEKK5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1).

MUC2_HUMAN
θ value	1.81305 (rank : 13)	NC score	0.083253 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	906	Shared Neighborhood Hits	22
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

TTLL5_HUMAN
θ value	1.81305 (rank : 14)	NC score	0.037206 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

LAMP3_HUMAN
θ value	2.36792 (rank : 15)	NC score	0.058582 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	53	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UQV4, O94781, Q8NEC8	Gene names	LAMP3, DCLAMP, TSC403
Domain Architecture	No domain graphic available
Description	Lysosome-associated membrane glycoprotein 3 precursor (LAMP-3) (Lysosomal-associated membrane protein 3) (DC-lysosome-associated membrane glycoprotein) (DC LAMP) (Protein TSC403) (CD208 antigen).

LEUK_MOUSE
θ value	2.36792 (rank : 16)	NC score	0.095240 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	147	Shared Neighborhood Hits	11
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

PODXL_HUMAN
θ value	2.36792 (rank : 17)	NC score	0.081952 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	191	Shared Neighborhood Hits	12
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

DSPP_HUMAN
θ value	3.0926 (rank : 18)	NC score	0.028997 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	645	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

MUCEN_HUMAN
θ value	3.0926 (rank : 19)	NC score	0.124237 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULC0, Q8NEY5, Q8WWE7, Q9NRM8	Gene names	EMCN, EMCN2. MUC14
Domain Architecture	No domain graphic available
Description	Endomucin precursor (Endomucin-2) (Gastric cancer antigen Ga34).

PTPRJ_MOUSE
θ value	3.0926 (rank : 20)	NC score	0.016336 (rank : 37)
Query Neighborhood Hits	34	Target Neighborhood Hits	188	Shared Neighborhood Hits	4
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

CKAP2_HUMAN
θ value	4.03905 (rank : 21)	NC score	0.040617 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWK9, Q3KRA5, Q5VXB4, Q8IWV5, Q8IWV6, Q96FH9, Q9H012, Q9H0D0, Q9H988, Q9HC49, Q9NVG4	Gene names	CKAP2, LB1, TMAP
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2 (Tumor-associated microtubule- associated protein) (CTCL tumor antigen se20-10).

LEUK_HUMAN
θ value	4.03905 (rank : 22)	NC score	0.087718 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	213	Shared Neighborhood Hits	15
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

SMAD4_HUMAN
θ value	4.03905 (rank : 23)	NC score	0.074349 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q13485	Gene names	SMAD4, DPC4, MADH4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (hSMAD4).

TARSH_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.045482 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	768	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

UTX_HUMAN
θ value	4.03905 (rank : 25)	NC score	0.031883 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	161	Shared Neighborhood Hits	4
SwissProt Accessions	O15550	Gene names	UTX
Domain Architecture
Description	Ubiquitously transcribed X chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the X chromosome).

WNK1_HUMAN
θ value	4.03905 (rank : 26)	NC score	0.012174 (rank : 38)
Query Neighborhood Hits	34	Target Neighborhood Hits	1158	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

CX020_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.046038 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NDZ0, Q5JXE5	Gene names	CXorf20
Domain Architecture	No domain graphic available
Description	Uncharacterized protein CXorf20.

HCFC1_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.046534 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	331	Shared Neighborhood Hits	15
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HDAC6_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.022657 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	145	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

NGL1_MOUSE
θ value	5.27518 (rank : 30)	NC score	0.018137 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	512	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C031, Q8BGH8	Gene names	Lrrc4c, Ngl1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

EVI2B_MOUSE
θ value	6.88961 (rank : 31)	NC score	0.035719 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VD58, Q3U1A3	Gene names	Evi2b
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

K1219_MOUSE
θ value	6.88961 (rank : 32)	NC score	0.027231 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BQZ4, Q80TH5, Q8BQN1	Gene names	Kiaa1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

NGL1_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.017942 (rank : 35)
Query Neighborhood Hits	34	Target Neighborhood Hits	511	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HCJ2, Q7L0N3	Gene names	LRRC4C, KIAA1580, NGL1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

REPS1_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.017937 (rank : 36)
Query Neighborhood Hits	34	Target Neighborhood Hits	205	Shared Neighborhood Hits	3
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

CD68_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.050628 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	P34810, Q96BI7	Gene names	CD68
Domain Architecture
Description	Macrosialin precursor (GP110) (CD68 antigen).

CK024_MOUSE
θ value	θ > 10 (rank : 36)	NC score	0.051035 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	307	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

MUC24_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.068729 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	10	Shared Neighborhood Hits	1
SwissProt Accessions	Q04900, Q5JSU6	Gene names	CD164
Domain Architecture
Description	Putative mucin core protein 24 precursor (Multi-glycosylated core protein 24) (MGC-24) (MUC-24) (CD164 antigen).

NFRKB_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.064867 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	211	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

PODXL_MOUSE
θ value	θ > 10 (rank : 39)	NC score	0.053265 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	130	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R0M4, Q9ESZ1	Gene names	Podxl, Pclp1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

Hits sorted by NC score

PORIM_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.3998e-69 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N131, Q8IWS2, Q96QV2	Gene names	TMEM123, KCT3
Domain Architecture	No domain graphic available
Description	Porimin precursor (Transmembrane protein 123) (Pro-oncosis receptor inducing membrane injury) (Keratinocytes-associated transmembrane protein 3) (KCT-3).

PORIM_MOUSE
NC score	0.802247 (rank : 2)	θ value	6.84181e-24 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	43	Shared Neighborhood Hits	8
SwissProt Accessions	Q91Z22, Q3T9F6, Q3TLL2, Q3U1R6, Q8CEX4	Gene names	Tmem123
Domain Architecture	No domain graphic available
Description	Porimin precursor (Transmembrane protein 123).

MUCEN_MOUSE
NC score	0.150873 (rank : 3)	θ value	0.21417 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R0H2, Q78KL2, Q9DCN9, Q9ULC1, Q9Z2I1	Gene names	Emcn, Muc14
Domain Architecture	No domain graphic available
Description	Endomucin precursor (Endomucin-1/2).

MUCEN_HUMAN
NC score	0.124237 (rank : 4)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULC0, Q8NEY5, Q8WWE7, Q9NRM8	Gene names	EMCN, EMCN2. MUC14
Domain Architecture	No domain graphic available
Description	Endomucin precursor (Endomucin-2) (Gastric cancer antigen Ga34).

SMAD4_MOUSE
NC score	0.096395 (rank : 5)	θ value	0.0113563 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	101	Shared Neighborhood Hits	6
SwissProt Accessions	P97471, Q9CW56	Gene names	Smad4, Dpc4, Madh4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4 homolog) (Smad4).

LEUK_MOUSE
NC score	0.095240 (rank : 6)	θ value	2.36792 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	147	Shared Neighborhood Hits	11
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

MUC5B_HUMAN
NC score	0.092944 (rank : 7)	θ value	1.06291 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	1020	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

LEUK_HUMAN
NC score	0.087718 (rank : 8)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	213	Shared Neighborhood Hits	15
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

NFRKB_MOUSE
NC score	0.084312 (rank : 9)	θ value	0.365318 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	393	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

MUC2_HUMAN
NC score	0.083253 (rank : 10)	θ value	1.81305 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	906	Shared Neighborhood Hits	22
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PODXL_HUMAN
NC score	0.081952 (rank : 11)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	191	Shared Neighborhood Hits	12
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

SMAD4_HUMAN
NC score	0.074349 (rank : 12)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q13485	Gene names	SMAD4, DPC4, MADH4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (hSMAD4).

MUC24_HUMAN
NC score	0.068729 (rank : 13)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	34	Target Neighborhood Hits	10	Shared Neighborhood Hits	1
SwissProt Accessions	Q04900, Q5JSU6	Gene names	CD164
Domain Architecture
Description	Putative mucin core protein 24 precursor (Multi-glycosylated core protein 24) (MGC-24) (MUC-24) (CD164 antigen).

GP112_HUMAN
NC score	0.066979 (rank : 14)	θ value	0.279714 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	441	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

NFRKB_HUMAN
NC score	0.064867 (rank : 15)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	34	Target Neighborhood Hits	211	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

LAMP3_HUMAN
NC score	0.058582 (rank : 16)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	53	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UQV4, O94781, Q8NEC8	Gene names	LAMP3, DCLAMP, TSC403
Domain Architecture	No domain graphic available
Description	Lysosome-associated membrane glycoprotein 3 precursor (LAMP-3) (Lysosomal-associated membrane protein 3) (DC-lysosome-associated membrane glycoprotein) (DC LAMP) (Protein TSC403) (CD208 antigen).

PODXL_MOUSE
NC score	0.053265 (rank : 17)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	34	Target Neighborhood Hits	130	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R0M4, Q9ESZ1	Gene names	Podxl, Pclp1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

CK024_MOUSE
NC score	0.051035 (rank : 18)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	34	Target Neighborhood Hits	307	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CD68_HUMAN
NC score	0.050628 (rank : 19)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	34	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	P34810, Q96BI7	Gene names	CD68
Domain Architecture
Description	Macrosialin precursor (GP110) (CD68 antigen).

HCFC1_HUMAN
NC score	0.046534 (rank : 20)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	331	Shared Neighborhood Hits	15
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

CX020_HUMAN
NC score	0.046038 (rank : 21)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NDZ0, Q5JXE5	Gene names	CXorf20
Domain Architecture	No domain graphic available
Description	Uncharacterized protein CXorf20.

TARSH_HUMAN
NC score	0.045482 (rank : 22)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	768	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

SON_HUMAN
NC score	0.044239 (rank : 23)	θ value	1.06291 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	1568	Shared Neighborhood Hits	14
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

CKAP2_HUMAN
NC score	0.040617 (rank : 24)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWK9, Q3KRA5, Q5VXB4, Q8IWV5, Q8IWV6, Q96FH9, Q9H012, Q9H0D0, Q9H988, Q9HC49, Q9NVG4	Gene names	CKAP2, LB1, TMAP
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2 (Tumor-associated microtubule- associated protein) (CTCL tumor antigen se20-10).

SP3_MOUSE
NC score	0.038508 (rank : 25)	θ value	0.0148317 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	731	Shared Neighborhood Hits	4
SwissProt Accessions	O70494, Q68FF2, Q8CF64, Q8K378	Gene names	Sp3
Domain Architecture	No domain graphic available
Description	Transcription factor Sp3.

TTLL5_HUMAN
NC score	0.037206 (rank : 26)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

SP3_HUMAN
NC score	0.037000 (rank : 27)	θ value	0.0431538 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	737	Shared Neighborhood Hits	4
SwissProt Accessions	Q02447, Q8TD56, Q9BQR1	Gene names	SP3
Domain Architecture
Description	Transcription factor Sp3 (SPR-2).

EVI2B_MOUSE
NC score	0.035719 (rank : 28)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VD58, Q3U1A3	Gene names	Evi2b
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

UTX_HUMAN
NC score	0.031883 (rank : 29)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	161	Shared Neighborhood Hits	4
SwissProt Accessions	O15550	Gene names	UTX
Domain Architecture
Description	Ubiquitously transcribed X chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the X chromosome).

DSPP_HUMAN
NC score	0.028997 (rank : 30)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	645	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

K1219_MOUSE
NC score	0.027231 (rank : 31)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BQZ4, Q80TH5, Q8BQN1	Gene names	Kiaa1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

ANGP1_MOUSE
NC score	0.026888 (rank : 32)	θ value	0.62314 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	252	Shared Neighborhood Hits	2
SwissProt Accessions	O08538	Gene names	Angpt1, Agpt
Domain Architecture
Description	Angiopoietin-1 precursor (ANG-1).

HDAC6_HUMAN
NC score	0.022657 (rank : 33)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	145	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

NGL1_MOUSE
NC score	0.018137 (rank : 34)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	512	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C031, Q8BGH8	Gene names	Lrrc4c, Ngl1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

NGL1_HUMAN
NC score	0.017942 (rank : 35)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	511	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HCJ2, Q7L0N3	Gene names	LRRC4C, KIAA1580, NGL1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

REPS1_HUMAN
NC score	0.017937 (rank : 36)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	205	Shared Neighborhood Hits	3
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

PTPRJ_MOUSE
NC score	0.016336 (rank : 37)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	188	Shared Neighborhood Hits	4
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

WNK1_HUMAN
NC score	0.012174 (rank : 38)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	1158	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

M3K5_HUMAN
NC score	0.009194 (rank : 39)	θ value	1.38821 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	868	Shared Neighborhood Hits	3
SwissProt Accessions	Q99683, Q5THN3, Q99461	Gene names	MAP3K5, ASK1, MAPKKK5, MEKK5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1).