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Network neighborhood for query Sequence : PDYN_HUMAN

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PDYN_HUMAN
SwissProt Accessions	P01213	Gene names	PDYN
Domain Architecture
Description	Beta-neoendorphin-dynorphin precursor (Proenkephalin B) (Preprodynorphin) [Contains: Beta-neoendorphin; Dynorphin; Leu- enkephalin; Rimorphin; Leumorphin].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PDYN_HUMAN
θ value	1.85788e-146 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	P01213	Gene names	PDYN
Domain Architecture
Description	Beta-neoendorphin-dynorphin precursor (Proenkephalin B) (Preprodynorphin) [Contains: Beta-neoendorphin; Dynorphin; Leu- enkephalin; Rimorphin; Leumorphin].

PDYN_MOUSE
θ value	2.73302e-81 (rank : 2)	NC score	0.981608 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	O35417	Gene names	Pdyn
Domain Architecture
Description	Beta-neoendorphin-dynorphin precursor (Proenkephalin B) (Preprodynorphin) [Contains: Alpha-neoendorphin; Dynorphin A; Leu- enkephalin; Dynorphin B].

PENK_HUMAN
θ value	4.29542e-18 (rank : 3)	NC score	0.701112 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	P01210	Gene names	PENK
Domain Architecture
Description	Proenkephalin A precursor [Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Gly-Leu; Leu- enkephalin; Met-enkephalin-Arg-Phe].

PENK_MOUSE
θ value	3.63628e-17 (rank : 4)	NC score	0.700636 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	P22005	Gene names	Penk, Penk1
Domain Architecture
Description	Proenkephalin A precursor [Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Ser-Leu; Leu- enkephalin; Met-enkephalin-Arg-Phe].

CLSPN_MOUSE
θ value	0.163984 (rank : 5)	NC score	0.075777 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	292	Shared Neighborhood Hits	4
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

PNOC_HUMAN
θ value	0.279714 (rank : 6)	NC score	0.225082 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q13519	Gene names	PNOC, OFQ
Domain Architecture
Description	Nociceptin precursor [Contains: Neuropeptide 1; Nociceptin (Orphanin FQ) (PPNOC); Neuropeptide 2].

PNOC_MOUSE
θ value	0.365318 (rank : 7)	NC score	0.221955 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q64387, Q61105, Q61938	Gene names	Pnoc, Npnc1
Domain Architecture
Description	Nociceptin precursor (N23K/N27K) [Contains: Neuropeptide 1; Nociceptin (Orphanin FQ) (PPNOC); Neuropeptide 2].

MYH10_MOUSE
θ value	1.38821 (rank : 8)	NC score	0.011303 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	1612	Shared Neighborhood Hits	5
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

CAC1S_MOUSE
θ value	2.36792 (rank : 9)	NC score	0.016517 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

MPDZ_MOUSE
θ value	2.36792 (rank : 10)	NC score	0.015547 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	298	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

MYH10_HUMAN
θ value	2.36792 (rank : 11)	NC score	0.010655 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	1620	Shared Neighborhood Hits	4
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

NSBP1_MOUSE
θ value	2.36792 (rank : 12)	NC score	0.021746 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	681	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

K1718_HUMAN
θ value	5.27518 (rank : 13)	NC score	0.013773 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	114	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

KLRA2_MOUSE
θ value	5.27518 (rank : 14)	NC score	0.016060 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q60660	Gene names	Klra2, Ly49-b, Ly49b
Domain Architecture
Description	Killer cell lectin-like receptor 2 (T-cell surface glycoprotein Ly- 49B) (Ly49-B antigen) (Lymphocyte antigen 49B).

NOP14_HUMAN
θ value	5.27518 (rank : 15)	NC score	0.025289 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	573	Shared Neighborhood Hits	6
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

CAC1S_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.013857 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CEND1_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.007717 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	284	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

Hits sorted by NC score

PDYN_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.85788e-146 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	P01213	Gene names	PDYN
Domain Architecture
Description	Beta-neoendorphin-dynorphin precursor (Proenkephalin B) (Preprodynorphin) [Contains: Beta-neoendorphin; Dynorphin; Leu- enkephalin; Rimorphin; Leumorphin].

PDYN_MOUSE
NC score	0.981608 (rank : 2)	θ value	2.73302e-81 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	O35417	Gene names	Pdyn
Domain Architecture
Description	Beta-neoendorphin-dynorphin precursor (Proenkephalin B) (Preprodynorphin) [Contains: Alpha-neoendorphin; Dynorphin A; Leu- enkephalin; Dynorphin B].

PENK_HUMAN
NC score	0.701112 (rank : 3)	θ value	4.29542e-18 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	P01210	Gene names	PENK
Domain Architecture
Description	Proenkephalin A precursor [Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Gly-Leu; Leu- enkephalin; Met-enkephalin-Arg-Phe].

PENK_MOUSE
NC score	0.700636 (rank : 4)	θ value	3.63628e-17 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	P22005	Gene names	Penk, Penk1
Domain Architecture
Description	Proenkephalin A precursor [Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Ser-Leu; Leu- enkephalin; Met-enkephalin-Arg-Phe].

PNOC_HUMAN
NC score	0.225082 (rank : 5)	θ value	0.279714 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q13519	Gene names	PNOC, OFQ
Domain Architecture
Description	Nociceptin precursor [Contains: Neuropeptide 1; Nociceptin (Orphanin FQ) (PPNOC); Neuropeptide 2].

PNOC_MOUSE
NC score	0.221955 (rank : 6)	θ value	0.365318 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q64387, Q61105, Q61938	Gene names	Pnoc, Npnc1
Domain Architecture
Description	Nociceptin precursor (N23K/N27K) [Contains: Neuropeptide 1; Nociceptin (Orphanin FQ) (PPNOC); Neuropeptide 2].

CLSPN_MOUSE
NC score	0.075777 (rank : 7)	θ value	0.163984 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	292	Shared Neighborhood Hits	4
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

NOP14_HUMAN
NC score	0.025289 (rank : 8)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	573	Shared Neighborhood Hits	6
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

NSBP1_MOUSE
NC score	0.021746 (rank : 9)	θ value	2.36792 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	681	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

CAC1S_MOUSE
NC score	0.016517 (rank : 10)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

KLRA2_MOUSE
NC score	0.016060 (rank : 11)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q60660	Gene names	Klra2, Ly49-b, Ly49b
Domain Architecture
Description	Killer cell lectin-like receptor 2 (T-cell surface glycoprotein Ly- 49B) (Ly49-B antigen) (Lymphocyte antigen 49B).

MPDZ_MOUSE
NC score	0.015547 (rank : 12)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	298	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

CAC1S_HUMAN
NC score	0.013857 (rank : 13)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

K1718_HUMAN
NC score	0.013773 (rank : 14)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	114	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

MYH10_MOUSE
NC score	0.011303 (rank : 15)	θ value	1.38821 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	1612	Shared Neighborhood Hits	5
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_HUMAN
NC score	0.010655 (rank : 16)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	1620	Shared Neighborhood Hits	4
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

CEND1_HUMAN
NC score	0.007717 (rank : 17)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	284	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).