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Network neighborhood for query Sequence : MA2C1_MOUSE

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MA2C1_MOUSE
SwissProt Accessions	Q91W89	Gene names	Man2c1
Domain Architecture
Description	Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MA2C1_HUMAN
θ value	0 (rank : 1)	NC score	0.996037 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NTJ4, Q13358, Q9UL64	Gene names	MAN2C1
Domain Architecture
Description	Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1) (Alpha mannosidase 6A8B).

MA2C1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q91W89	Gene names	Man2c1
Domain Architecture
Description	Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1).

MA2A1_MOUSE
θ value	3.41135e-07 (rank : 3)	NC score	0.305409 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	P27046	Gene names	Man2a1, Mana2
Domain Architecture
Description	Alpha-mannosidase 2 (EC 3.2.1.114) (Alpha-mannosidase II) (Mannosyl- oligosaccharide 1,3-1,6-alpha-mannosidase) (MAN II) (Golgi alpha- mannosidase II) (Mannosidase alpha class 2A member 1) (AMAN II).

MA2A1_HUMAN
θ value	8.40245e-06 (rank : 4)	NC score	0.297152 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q16706, Q16767	Gene names	MAN2A1, MANA2
Domain Architecture
Description	Alpha-mannosidase 2 (EC 3.2.1.114) (Alpha-mannosidase II) (Mannosyl- oligosaccharide 1,3-1,6-alpha-mannosidase) (MAN II) (Golgi alpha- mannosidase II) (Mannosidase alpha class 2A member 1).

MA2A2_HUMAN
θ value	0.000121331 (rank : 5)	NC score	0.291008 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	P49641, Q13754	Gene names	MAN2A2, MANA2X
Domain Architecture
Description	Alpha-mannosidase IIx (EC 3.2.1.114) (Mannosyl-oligosaccharide 1,3- 1,6-alpha-mannosidase) (MAN IIx) (Mannosidase alpha class 2A member 2).

MA2B2_HUMAN
θ value	0.000461057 (rank : 6)	NC score	0.275051 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2E5, Q66MP2, Q86T67	Gene names	MAN2B2, KIAA0935
Domain Architecture
Description	Epididymis-specific alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase alpha class 2B member 2).

MA2B1_MOUSE
θ value	0.000786445 (rank : 7)	NC score	0.252436 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	O09159, O55037, Q64443, Q9DBQ1	Gene names	Man2b1, Laman, Man2b, Manb
Domain Architecture
Description	Lysosomal alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase, alpha B) (Lysosomal acid alpha-mannosidase) (Laman) (Mannosidase alpha class 2B member 1).

MA2B2_MOUSE
θ value	0.00102713 (rank : 8)	NC score	0.271798 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	O54782, Q69ZV1, Q8BH85, Q9DBK2	Gene names	Man2b2, Kiaa0935
Domain Architecture
Description	Epididymis-specific alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase alpha class 2B member 2).

MA2B1_HUMAN
θ value	0.0113563 (rank : 9)	NC score	0.222301 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O00754, O15330, Q16680, Q93094, Q9BW13	Gene names	MAN2B1, LAMAN, MANB
Domain Architecture
Description	Lysosomal alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase, alpha B) (Lysosomal acid alpha-mannosidase) (Laman) (Mannosidase alpha class 2B member 1) [Contains: Lysosomal alpha-mannosidase A peptide; Lysosomal alpha-mannosidase B peptide; Lysosomal alpha-mannosidase C peptide; Lysosomal alpha-mannosidase D peptide; Lysosomal alpha- mannosidase E peptide].

GAMT_MOUSE
θ value	1.06291 (rank : 10)	NC score	0.069047 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	O35969, Q3TZ58, Q3US90	Gene names	Gamt
Domain Architecture	No domain graphic available
Description	Guanidinoacetate N-methyltransferase (EC 2.1.1.2).

RXRA_HUMAN
θ value	1.06291 (rank : 11)	NC score	0.022333 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	223	Shared Neighborhood Hits	4
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

CU070_MOUSE
θ value	1.38821 (rank : 12)	NC score	0.065235 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	P58468	Gene names
Domain Architecture	No domain graphic available
Description	Protein C21orf70 homolog.

KIF6_HUMAN
θ value	1.38821 (rank : 13)	NC score	0.015250 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	271	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZMV9, Q2MDE3, Q2MDE4, Q5T8J6, Q6ZWE3, Q86T87, Q8WTV4	Gene names	KIF6, C6orf102
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF6.

RXRA_MOUSE
θ value	1.81305 (rank : 14)	NC score	0.020624 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

Hits sorted by NC score

MA2C1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q91W89	Gene names	Man2c1
Domain Architecture
Description	Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1).

MA2C1_HUMAN
NC score	0.996037 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NTJ4, Q13358, Q9UL64	Gene names	MAN2C1
Domain Architecture
Description	Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1) (Alpha mannosidase 6A8B).

MA2A1_MOUSE
NC score	0.305409 (rank : 3)	θ value	3.41135e-07 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	P27046	Gene names	Man2a1, Mana2
Domain Architecture
Description	Alpha-mannosidase 2 (EC 3.2.1.114) (Alpha-mannosidase II) (Mannosyl- oligosaccharide 1,3-1,6-alpha-mannosidase) (MAN II) (Golgi alpha- mannosidase II) (Mannosidase alpha class 2A member 1) (AMAN II).

MA2A1_HUMAN
NC score	0.297152 (rank : 4)	θ value	8.40245e-06 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q16706, Q16767	Gene names	MAN2A1, MANA2
Domain Architecture
Description	Alpha-mannosidase 2 (EC 3.2.1.114) (Alpha-mannosidase II) (Mannosyl- oligosaccharide 1,3-1,6-alpha-mannosidase) (MAN II) (Golgi alpha- mannosidase II) (Mannosidase alpha class 2A member 1).

MA2A2_HUMAN
NC score	0.291008 (rank : 5)	θ value	0.000121331 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	P49641, Q13754	Gene names	MAN2A2, MANA2X
Domain Architecture
Description	Alpha-mannosidase IIx (EC 3.2.1.114) (Mannosyl-oligosaccharide 1,3- 1,6-alpha-mannosidase) (MAN IIx) (Mannosidase alpha class 2A member 2).

MA2B2_HUMAN
NC score	0.275051 (rank : 6)	θ value	0.000461057 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2E5, Q66MP2, Q86T67	Gene names	MAN2B2, KIAA0935
Domain Architecture
Description	Epididymis-specific alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase alpha class 2B member 2).

MA2B2_MOUSE
NC score	0.271798 (rank : 7)	θ value	0.00102713 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	O54782, Q69ZV1, Q8BH85, Q9DBK2	Gene names	Man2b2, Kiaa0935
Domain Architecture
Description	Epididymis-specific alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase alpha class 2B member 2).

MA2B1_MOUSE
NC score	0.252436 (rank : 8)	θ value	0.000786445 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	O09159, O55037, Q64443, Q9DBQ1	Gene names	Man2b1, Laman, Man2b, Manb
Domain Architecture
Description	Lysosomal alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase, alpha B) (Lysosomal acid alpha-mannosidase) (Laman) (Mannosidase alpha class 2B member 1).

MA2B1_HUMAN
NC score	0.222301 (rank : 9)	θ value	0.0113563 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O00754, O15330, Q16680, Q93094, Q9BW13	Gene names	MAN2B1, LAMAN, MANB
Domain Architecture
Description	Lysosomal alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase, alpha B) (Lysosomal acid alpha-mannosidase) (Laman) (Mannosidase alpha class 2B member 1) [Contains: Lysosomal alpha-mannosidase A peptide; Lysosomal alpha-mannosidase B peptide; Lysosomal alpha-mannosidase C peptide; Lysosomal alpha-mannosidase D peptide; Lysosomal alpha- mannosidase E peptide].

GAMT_MOUSE
NC score	0.069047 (rank : 10)	θ value	1.06291 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	O35969, Q3TZ58, Q3US90	Gene names	Gamt
Domain Architecture	No domain graphic available
Description	Guanidinoacetate N-methyltransferase (EC 2.1.1.2).

CU070_MOUSE
NC score	0.065235 (rank : 11)	θ value	1.38821 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	P58468	Gene names
Domain Architecture	No domain graphic available
Description	Protein C21orf70 homolog.

RXRA_HUMAN
NC score	0.022333 (rank : 12)	θ value	1.06291 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	223	Shared Neighborhood Hits	4
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRA_MOUSE
NC score	0.020624 (rank : 13)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

KIF6_HUMAN
NC score	0.015250 (rank : 14)	θ value	1.38821 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	271	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZMV9, Q2MDE3, Q2MDE4, Q5T8J6, Q6ZWE3, Q86T87, Q8WTV4	Gene names	KIF6, C6orf102
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF6.