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Network neighborhood for query Sequence : LIGA_HUMAN

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LIGA_HUMAN
SwissProt Accessions	P41214, Q9NR27, Q9NSN0, Q9NV18, Q9NZ21	Gene names	LGTN, HCA56
Domain Architecture
Description	Ligatin (Hepatocellular carcinoma-associated antigen 56).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LIGA_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	P41214, Q9NR27, Q9NSN0, Q9NV18, Q9NZ21	Gene names	LGTN, HCA56
Domain Architecture
Description	Ligatin (Hepatocellular carcinoma-associated antigen 56).

LIGA_MOUSE
θ value	0 (rank : 2)	NC score	0.992390 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q61211, Q3TDE0, Q3THV5, Q3TTP4, Q8C491, Q8CBF1, Q8CC17, Q8R1I9, Q8R3M5	Gene names	Lgtn
Domain Architecture	No domain graphic available
Description	Ligatin.

GUC2F_HUMAN
θ value	0.47712 (rank : 3)	NC score	0.014033 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	740	Shared Neighborhood Hits	4
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

NEK1_HUMAN
θ value	0.62314 (rank : 4)	NC score	0.010279 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	1129	Shared Neighborhood Hits	5
SwissProt Accessions	Q96PY6, Q9Y594	Gene names	NEK1, KIAA1901
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1) (NY-REN-55 antigen).

SDPR_MOUSE
θ value	1.06291 (rank : 5)	NC score	0.029967 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	485	Shared Neighborhood Hits	5
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

NEK1_MOUSE
θ value	1.38821 (rank : 6)	NC score	0.009408 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	1311	Shared Neighborhood Hits	7
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

HOOK3_MOUSE
θ value	1.81305 (rank : 7)	NC score	0.010630 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	1007	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

OSBL1_HUMAN
θ value	1.81305 (rank : 8)	NC score	0.013332 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	368	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

AF17_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.019798 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	230	Shared Neighborhood Hits	7
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

PSD4_HUMAN
θ value	2.36792 (rank : 10)	NC score	0.021402 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	178	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

SAP_MOUSE
θ value	2.36792 (rank : 11)	NC score	0.046973 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q61207, Q60861, Q64006, Q64219	Gene names	Psap, Sgp1
Domain Architecture
Description	Sulfated glycoprotein 1 precursor (SGP-1) (Prosaposin).

3HIDH_HUMAN
θ value	3.0926 (rank : 12)	NC score	0.032272 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P31937, Q9UDN3	Gene names	HIBADH
Domain Architecture
Description	3-hydroxyisobutyrate dehydrogenase, mitochondrial precursor (EC 1.1.1.31) (HIBADH).

ANK2_HUMAN
θ value	5.27518 (rank : 13)	NC score	0.006981 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	1615	Shared Neighborhood Hits	8
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

RAI1_HUMAN
θ value	5.27518 (rank : 14)	NC score	0.019602 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	360	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

ZSWM2_MOUSE
θ value	6.88961 (rank : 15)	NC score	0.021599 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	132	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

CAS1_MOUSE
θ value	8.99809 (rank : 16)	NC score	0.024571 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	P19228	Gene names	Csn1s1, Csn1, Csna
Domain Architecture
Description	Alpha-s1-casein precursor.

INADL_MOUSE
θ value	8.99809 (rank : 17)	NC score	0.006676 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	290	Shared Neighborhood Hits	3
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

K1543_MOUSE
θ value	8.99809 (rank : 18)	NC score	0.012401 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	497	Shared Neighborhood Hits	5
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

MAP1B_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.010402 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	977	Shared Neighborhood Hits	8
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

P3C2A_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.007146 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

PCLO_MOUSE
θ value	8.99809 (rank : 21)	NC score	0.006586 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	2275	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TCF20_HUMAN
θ value	8.99809 (rank : 22)	NC score	0.015762 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	323	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

ZSWM2_HUMAN
θ value	8.99809 (rank : 23)	NC score	0.019913 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	151	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

Hits sorted by NC score

LIGA_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	P41214, Q9NR27, Q9NSN0, Q9NV18, Q9NZ21	Gene names	LGTN, HCA56
Domain Architecture
Description	Ligatin (Hepatocellular carcinoma-associated antigen 56).

LIGA_MOUSE
NC score	0.992390 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q61211, Q3TDE0, Q3THV5, Q3TTP4, Q8C491, Q8CBF1, Q8CC17, Q8R1I9, Q8R3M5	Gene names	Lgtn
Domain Architecture	No domain graphic available
Description	Ligatin.

SAP_MOUSE
NC score	0.046973 (rank : 3)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q61207, Q60861, Q64006, Q64219	Gene names	Psap, Sgp1
Domain Architecture
Description	Sulfated glycoprotein 1 precursor (SGP-1) (Prosaposin).

3HIDH_HUMAN
NC score	0.032272 (rank : 4)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P31937, Q9UDN3	Gene names	HIBADH
Domain Architecture
Description	3-hydroxyisobutyrate dehydrogenase, mitochondrial precursor (EC 1.1.1.31) (HIBADH).

SDPR_MOUSE
NC score	0.029967 (rank : 5)	θ value	1.06291 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	485	Shared Neighborhood Hits	5
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

CAS1_MOUSE
NC score	0.024571 (rank : 6)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	P19228	Gene names	Csn1s1, Csn1, Csna
Domain Architecture
Description	Alpha-s1-casein precursor.

ZSWM2_MOUSE
NC score	0.021599 (rank : 7)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	132	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

PSD4_HUMAN
NC score	0.021402 (rank : 8)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	178	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

ZSWM2_HUMAN
NC score	0.019913 (rank : 9)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	151	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

AF17_HUMAN
NC score	0.019798 (rank : 10)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	230	Shared Neighborhood Hits	7
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

RAI1_HUMAN
NC score	0.019602 (rank : 11)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	360	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

TCF20_HUMAN
NC score	0.015762 (rank : 12)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	323	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

GUC2F_HUMAN
NC score	0.014033 (rank : 13)	θ value	0.47712 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	740	Shared Neighborhood Hits	4
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

OSBL1_HUMAN
NC score	0.013332 (rank : 14)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	368	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

K1543_MOUSE
NC score	0.012401 (rank : 15)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	497	Shared Neighborhood Hits	5
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

HOOK3_MOUSE
NC score	0.010630 (rank : 16)	θ value	1.81305 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	1007	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

MAP1B_MOUSE
NC score	0.010402 (rank : 17)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	977	Shared Neighborhood Hits	8
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

NEK1_HUMAN
NC score	0.010279 (rank : 18)	θ value	0.62314 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	1129	Shared Neighborhood Hits	5
SwissProt Accessions	Q96PY6, Q9Y594	Gene names	NEK1, KIAA1901
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1) (NY-REN-55 antigen).

NEK1_MOUSE
NC score	0.009408 (rank : 19)	θ value	1.38821 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	1311	Shared Neighborhood Hits	7
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

P3C2A_HUMAN
NC score	0.007146 (rank : 20)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

ANK2_HUMAN
NC score	0.006981 (rank : 21)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	1615	Shared Neighborhood Hits	8
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

INADL_MOUSE
NC score	0.006676 (rank : 22)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	290	Shared Neighborhood Hits	3
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

PCLO_MOUSE
NC score	0.006586 (rank : 23)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	2275	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).