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Network neighborhood for query Sequence : LARGE_HUMAN

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LARGE_HUMAN
SwissProt Accessions	O95461, O60348, Q9UGD1, Q9UGE7, Q9UGG3, Q9UGZ8, Q9UH22	Gene names	LARGE, KIAA0609, LARGE1
Domain Architecture
Description	Glycosyltransferase-like protein LARGE1 (EC 2.4.-.-) (Acetylglucosaminyltransferase-like 1A).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LARG2_HUMAN
θ value	0 (rank : 1)	NC score	0.993303 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N3Y3, Q8N8Y6, Q8NAK3, Q8WY62	Gene names	GYLTL1B
Domain Architecture	No domain graphic available
Description	Glycosyltransferase-like protein LARGE2 (EC 2.4.-.-) (Glycosyltransferase-like 1B).

LARG2_MOUSE
θ value	0 (rank : 2)	NC score	0.992768 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q5XPT3, Q5XPT2, Q8BJZ8, Q8K253	Gene names	Gyltl1b
Domain Architecture	No domain graphic available
Description	Glycosyltransferase-like protein LARGE2 (EC 2.4.-.-) (Glycosyltransferase-like 1B).

LARGE_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	O95461, O60348, Q9UGD1, Q9UGE7, Q9UGG3, Q9UGZ8, Q9UH22	Gene names	LARGE, KIAA0609, LARGE1
Domain Architecture
Description	Glycosyltransferase-like protein LARGE1 (EC 2.4.-.-) (Acetylglucosaminyltransferase-like 1A).

LARGE_MOUSE
θ value	0 (rank : 4)	NC score	0.999354 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z1M7, Q497S9, Q6P7U2, Q80TW0	Gene names	Large, Kiaa0609, Large1
Domain Architecture
Description	Glycosyltransferase-like protein LARGE1 (EC 2.4.-.-) (Acetylglucosaminyltransferase-like 1A).

B3GN6_MOUSE
θ value	7.80994e-28 (rank : 5)	NC score	0.715597 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BWP8, Q3TY43, Q8BJH9, Q99LW7	Gene names	B3gnt6
Domain Architecture	No domain graphic available
Description	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase (EC 2.4.1.149) (Poly-N-acetyllactosamine extension enzyme) (I-beta- 1,3-N-acetylglucosaminyltransferase) (iGnT) (UDP-GlcNAc:betaGal beta- 1,3-N-acetylglucosaminyltransferase 6).

B3GN6_HUMAN
θ value	1.47289e-26 (rank : 6)	NC score	0.704707 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	O43505, Q4TTN0	Gene names	B3GNT6
Domain Architecture	No domain graphic available
Description	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase (EC 2.4.1.149) (Poly-N-acetyllactosamine extension enzyme) (I-beta- 1,3-N-acetylglucosaminyltransferase) (iGnT) (UDP-GlcNAc:betaGal beta- 1,3-N-acetylglucosaminyltransferase 6).

CC021_HUMAN
θ value	9.26847e-13 (rank : 7)	NC score	0.541512 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NBI6, Q8NAL3, Q8WV03, Q96ME0	Gene names	C3orf21
Domain Architecture	No domain graphic available
Description	Protein C3orf21.

CC021_MOUSE
θ value	3.52202e-12 (rank : 8)	NC score	0.536019 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q3U4G3, Q3TLX5, Q8K2I0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C3orf21 homolog.

RTN2_MOUSE
θ value	0.279714 (rank : 9)	NC score	0.048882 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	O70622, O70620	Gene names	Rtn2, Nspl1
Domain Architecture
Description	Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (NSPLI).

MYOC_HUMAN
θ value	0.62314 (rank : 10)	NC score	0.025580 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	489	Shared Neighborhood Hits	3
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

ZN644_HUMAN
θ value	2.36792 (rank : 11)	NC score	0.011628 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	704	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H582, Q5TCC0, Q6BEP7, Q6P446, Q6PI06, Q7LG67, Q9ULJ9	Gene names	ZNF644, KIAA1221, ZEP2
Domain Architecture	No domain graphic available
Description	Zinc finger protein 644 (Zinc finger motif enhancer-binding protein 2) (Zep-2).

UGGG1_MOUSE
θ value	3.0926 (rank : 12)	NC score	0.029946 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P5E4, Q6NV70	Gene names	Ugcgl1, Gt, Uggt, Ugt1, Ugtr
Domain Architecture	No domain graphic available
Description	UDP-glucose:glycoprotein glucosyltransferase 1 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase).

RF1M_HUMAN
θ value	4.03905 (rank : 13)	NC score	0.039056 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	O75570, Q5T6Y5, Q8IUQ6	Gene names	MTRF1
Domain Architecture
Description	Peptide chain release factor 1, mitochondrial precursor (MRF-1).

UGGG1_HUMAN
θ value	4.03905 (rank : 14)	NC score	0.027533 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYU2, Q8IW30, Q9H8I4	Gene names	UGCGL1, GT, UGGT, UGT1, UGTR
Domain Architecture	No domain graphic available
Description	UDP-glucose:glycoprotein glucosyltransferase 1 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase) (HUGT1).

BTBD7_MOUSE
θ value	5.27518 (rank : 15)	NC score	0.011615 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	228	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CFE5, Q80TC3, Q8BZY9	Gene names	Btbd7, Kiaa1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

WDR79_HUMAN
θ value	5.27518 (rank : 16)	NC score	0.009958 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	246	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BUR4, Q9NW09	Gene names	WDR79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

FPRP_MOUSE
θ value	6.88961 (rank : 17)	NC score	0.016171 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WV91	Gene names	Ptgfrn, Fprp
Domain Architecture
Description	Prostaglandin F2 receptor negative regulator precursor (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD315 antigen).

RF1M_MOUSE
θ value	6.88961 (rank : 18)	NC score	0.032637 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K126	Gene names	Mtrf1
Domain Architecture
Description	Peptide chain release factor 1, mitochondrial precursor (MRF-1).

Hits sorted by NC score

LARGE_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	O95461, O60348, Q9UGD1, Q9UGE7, Q9UGG3, Q9UGZ8, Q9UH22	Gene names	LARGE, KIAA0609, LARGE1
Domain Architecture
Description	Glycosyltransferase-like protein LARGE1 (EC 2.4.-.-) (Acetylglucosaminyltransferase-like 1A).

LARGE_MOUSE
NC score	0.999354 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z1M7, Q497S9, Q6P7U2, Q80TW0	Gene names	Large, Kiaa0609, Large1
Domain Architecture
Description	Glycosyltransferase-like protein LARGE1 (EC 2.4.-.-) (Acetylglucosaminyltransferase-like 1A).

LARG2_HUMAN
NC score	0.993303 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N3Y3, Q8N8Y6, Q8NAK3, Q8WY62	Gene names	GYLTL1B
Domain Architecture	No domain graphic available
Description	Glycosyltransferase-like protein LARGE2 (EC 2.4.-.-) (Glycosyltransferase-like 1B).

LARG2_MOUSE
NC score	0.992768 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q5XPT3, Q5XPT2, Q8BJZ8, Q8K253	Gene names	Gyltl1b
Domain Architecture	No domain graphic available
Description	Glycosyltransferase-like protein LARGE2 (EC 2.4.-.-) (Glycosyltransferase-like 1B).

B3GN6_MOUSE
NC score	0.715597 (rank : 5)	θ value	7.80994e-28 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BWP8, Q3TY43, Q8BJH9, Q99LW7	Gene names	B3gnt6
Domain Architecture	No domain graphic available
Description	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase (EC 2.4.1.149) (Poly-N-acetyllactosamine extension enzyme) (I-beta- 1,3-N-acetylglucosaminyltransferase) (iGnT) (UDP-GlcNAc:betaGal beta- 1,3-N-acetylglucosaminyltransferase 6).

B3GN6_HUMAN
NC score	0.704707 (rank : 6)	θ value	1.47289e-26 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	O43505, Q4TTN0	Gene names	B3GNT6
Domain Architecture	No domain graphic available
Description	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase (EC 2.4.1.149) (Poly-N-acetyllactosamine extension enzyme) (I-beta- 1,3-N-acetylglucosaminyltransferase) (iGnT) (UDP-GlcNAc:betaGal beta- 1,3-N-acetylglucosaminyltransferase 6).

CC021_HUMAN
NC score	0.541512 (rank : 7)	θ value	9.26847e-13 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NBI6, Q8NAL3, Q8WV03, Q96ME0	Gene names	C3orf21
Domain Architecture	No domain graphic available
Description	Protein C3orf21.

CC021_MOUSE
NC score	0.536019 (rank : 8)	θ value	3.52202e-12 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q3U4G3, Q3TLX5, Q8K2I0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C3orf21 homolog.

RTN2_MOUSE
NC score	0.048882 (rank : 9)	θ value	0.279714 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	O70622, O70620	Gene names	Rtn2, Nspl1
Domain Architecture
Description	Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (NSPLI).

RF1M_HUMAN
NC score	0.039056 (rank : 10)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	O75570, Q5T6Y5, Q8IUQ6	Gene names	MTRF1
Domain Architecture
Description	Peptide chain release factor 1, mitochondrial precursor (MRF-1).

RF1M_MOUSE
NC score	0.032637 (rank : 11)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K126	Gene names	Mtrf1
Domain Architecture
Description	Peptide chain release factor 1, mitochondrial precursor (MRF-1).

UGGG1_MOUSE
NC score	0.029946 (rank : 12)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P5E4, Q6NV70	Gene names	Ugcgl1, Gt, Uggt, Ugt1, Ugtr
Domain Architecture	No domain graphic available
Description	UDP-glucose:glycoprotein glucosyltransferase 1 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase).

UGGG1_HUMAN
NC score	0.027533 (rank : 13)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYU2, Q8IW30, Q9H8I4	Gene names	UGCGL1, GT, UGGT, UGT1, UGTR
Domain Architecture	No domain graphic available
Description	UDP-glucose:glycoprotein glucosyltransferase 1 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase) (HUGT1).

MYOC_HUMAN
NC score	0.025580 (rank : 14)	θ value	0.62314 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	489	Shared Neighborhood Hits	3
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

FPRP_MOUSE
NC score	0.016171 (rank : 15)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WV91	Gene names	Ptgfrn, Fprp
Domain Architecture
Description	Prostaglandin F2 receptor negative regulator precursor (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD315 antigen).

ZN644_HUMAN
NC score	0.011628 (rank : 16)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	704	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H582, Q5TCC0, Q6BEP7, Q6P446, Q6PI06, Q7LG67, Q9ULJ9	Gene names	ZNF644, KIAA1221, ZEP2
Domain Architecture	No domain graphic available
Description	Zinc finger protein 644 (Zinc finger motif enhancer-binding protein 2) (Zep-2).

BTBD7_MOUSE
NC score	0.011615 (rank : 17)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	228	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CFE5, Q80TC3, Q8BZY9	Gene names	Btbd7, Kiaa1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

WDR79_HUMAN
NC score	0.009958 (rank : 18)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	246	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BUR4, Q9NW09	Gene names	WDR79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.