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Network neighborhood for query Sequence : EXTL2_MOUSE

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EXTL2_MOUSE
SwissProt Accessions	Q9ES89, Q505Q8, Q9CX90	Gene names	Extl2, Extr2
Domain Architecture
Description	Exostosin-like 2 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Alpha-1,4-N- acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EXTL2_MOUSE
θ value	1.07914e-178 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ES89, Q505Q8, Q9CX90	Gene names	Extl2, Extr2
Domain Architecture
Description	Exostosin-like 2 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Alpha-1,4-N- acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2).

EXTL2_HUMAN
θ value	1.16101e-156 (rank : 2)	NC score	0.998839 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	15	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UBQ6	Gene names	EXTL2, EXTR2
Domain Architecture	No domain graphic available
Description	Exostosin-like 2 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Alpha-1,4-N- acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2).

EXT2_MOUSE
θ value	7.29293e-34 (rank : 3)	NC score	0.844420 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	P70428, P70395, Q923D6	Gene names	Ext2
Domain Architecture
Description	Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2 homolog).

EXT2_HUMAN
θ value	1.6247e-33 (rank : 4)	NC score	0.843772 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q93063, O15288	Gene names	EXT2
Domain Architecture
Description	Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXT2) (Multiple exostoses protein 2).

EXTL3_HUMAN
θ value	1.6247e-33 (rank : 5)	NC score	0.825896 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	113	Shared Neighborhood Hits	10
SwissProt Accessions	O43909, O00225	Gene names	EXTL3, EXTL1L, EXTR1, KIAA0519
Domain Architecture
Description	Exostosin-like 3 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXTL3) (Multiple exostosis-like protein 3) (Hereditary multiple exostoses gene isolog) (EXT-related protein 1).

EXTL3_MOUSE
θ value	2.77131e-33 (rank : 6)	NC score	0.826039 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	108	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WVL6	Gene names	Extl3
Domain Architecture
Description	Exostosin-like 3 (EC 2.4.1.-) (Multiple exostosis-like protein 3).

EXT1_MOUSE
θ value	1.5242e-23 (rank : 7)	NC score	0.793246 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	P97464, Q61546	Gene names	Ext1
Domain Architecture
Description	Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 1 homolog).

EXT1_HUMAN
θ value	1.99067e-23 (rank : 8)	NC score	0.792929 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q16394, Q9BVI9	Gene names	EXT1
Domain Architecture
Description	Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXT1) (Multiple exostoses protein 1).

EXTL1_MOUSE
θ value	6.62687e-19 (rank : 9)	NC score	0.772529 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JKV7	Gene names	Extl1
Domain Architecture
Description	Exostosin-like 1 (EC 2.4.1.224) (Glucuronosyl-N-acetylglucosaminyl- proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Exostosin-L) (Multiple exostosis-like protein).

EXTL1_HUMAN
θ value	5.8054e-15 (rank : 10)	NC score	0.758362 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q92935, Q6GSC1	Gene names	EXTL1, EXTL
Domain Architecture
Description	Exostosin-like 1 (EC 2.4.1.224) (Glucuronosyl-N-acetylglucosaminyl- proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Exostosin-L) (Multiple exostosis-like protein).

PADI3_MOUSE
θ value	4.03905 (rank : 11)	NC score	0.013675 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z184	Gene names	Padi3, Pdi3
Domain Architecture
Description	Protein-arginine deiminase type-3 (EC 3.5.3.15) (Protein-arginine deiminase type III) (Peptidylarginine deiminase III).

Hits sorted by NC score

EXTL2_MOUSE
NC score	0.999962 (rank : 1)	θ value	1.07914e-178 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ES89, Q505Q8, Q9CX90	Gene names	Extl2, Extr2
Domain Architecture
Description	Exostosin-like 2 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Alpha-1,4-N- acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2).

EXTL2_HUMAN
NC score	0.998839 (rank : 2)	θ value	1.16101e-156 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	15	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UBQ6	Gene names	EXTL2, EXTR2
Domain Architecture	No domain graphic available
Description	Exostosin-like 2 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Alpha-1,4-N- acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2).

EXT2_MOUSE
NC score	0.844420 (rank : 3)	θ value	7.29293e-34 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	P70428, P70395, Q923D6	Gene names	Ext2
Domain Architecture
Description	Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2 homolog).

EXT2_HUMAN
NC score	0.843772 (rank : 4)	θ value	1.6247e-33 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q93063, O15288	Gene names	EXT2
Domain Architecture
Description	Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXT2) (Multiple exostoses protein 2).

EXTL3_MOUSE
NC score	0.826039 (rank : 5)	θ value	2.77131e-33 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	108	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WVL6	Gene names	Extl3
Domain Architecture
Description	Exostosin-like 3 (EC 2.4.1.-) (Multiple exostosis-like protein 3).

EXTL3_HUMAN
NC score	0.825896 (rank : 6)	θ value	1.6247e-33 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	113	Shared Neighborhood Hits	10
SwissProt Accessions	O43909, O00225	Gene names	EXTL3, EXTL1L, EXTR1, KIAA0519
Domain Architecture
Description	Exostosin-like 3 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXTL3) (Multiple exostosis-like protein 3) (Hereditary multiple exostoses gene isolog) (EXT-related protein 1).

EXT1_MOUSE
NC score	0.793246 (rank : 7)	θ value	1.5242e-23 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	P97464, Q61546	Gene names	Ext1
Domain Architecture
Description	Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 1 homolog).

EXT1_HUMAN
NC score	0.792929 (rank : 8)	θ value	1.99067e-23 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q16394, Q9BVI9	Gene names	EXT1
Domain Architecture
Description	Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXT1) (Multiple exostoses protein 1).

EXTL1_MOUSE
NC score	0.772529 (rank : 9)	θ value	6.62687e-19 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JKV7	Gene names	Extl1
Domain Architecture
Description	Exostosin-like 1 (EC 2.4.1.224) (Glucuronosyl-N-acetylglucosaminyl- proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Exostosin-L) (Multiple exostosis-like protein).

EXTL1_HUMAN
NC score	0.758362 (rank : 10)	θ value	5.8054e-15 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q92935, Q6GSC1	Gene names	EXTL1, EXTL
Domain Architecture
Description	Exostosin-like 1 (EC 2.4.1.224) (Glucuronosyl-N-acetylglucosaminyl- proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Exostosin-L) (Multiple exostosis-like protein).

PADI3_MOUSE
NC score	0.013675 (rank : 11)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z184	Gene names	Padi3, Pdi3
Domain Architecture
Description	Protein-arginine deiminase type-3 (EC 3.5.3.15) (Protein-arginine deiminase type III) (Peptidylarginine deiminase III).