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Network neighborhood for query Sequence : ENH4_HUMAN

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ENH4_HUMAN
SwissProt Accessions	Q96L62	Gene names
Domain Architecture
Description	HERV-H_1q41 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-Hcl.7) [Contains: Surface protein (SU); Transmembrane protein (TM)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ENH1_HUMAN
θ value	0 (rank : 1)	NC score	0.926625 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q9N2K0, O00354, Q96L63, Q9UNM3	Gene names
Domain Architecture
Description	HERV-H_2q24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p62) (Env protein HERV-H19) (HERV- H/env62) (Env protein HERV-Hcl.3) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH2_HUMAN
θ value	0 (rank : 2)	NC score	0.942204 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q9N2J9	Gene names
Domain Architecture
Description	HERV-H_3q26 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p60) (HERV-H/env60) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH3_HUMAN
θ value	0 (rank : 3)	NC score	0.952567 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	30	Shared Neighborhood Hits	13
SwissProt Accessions	Q9N2J8	Gene names
Domain Architecture
Description	HERV-H_2q24.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p59) (HERV-H/env59) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH4_HUMAN
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q96L62	Gene names
Domain Architecture
Description	HERV-H_1q41 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-Hcl.7) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH5_HUMAN
θ value	6.77497e-173 (rank : 5)	NC score	0.997910 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	P61549	Gene names
Domain Architecture	No domain graphic available
Description	HERV-H_19p13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein RGH1) (Env protein RTLV-H) [Includes: Surface protein (SU)].

EFR1_HUMAN
θ value	7.06379e-29 (rank : 6)	NC score	0.787569 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P60508	Gene names	ERVFRDE1
Domain Architecture
Description	HERV-FRD_6p24.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-FRD) (Syncytin-2) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENW1_HUMAN
θ value	0.0736092 (rank : 7)	NC score	0.519549 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	22	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UQF0, O95244, O95245, Q8NHY7, Q9NRZ2, Q9NZG3	Gene names	ERVWE1
Domain Architecture
Description	HERV-W_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein gPr73) (HERV-7q Envelope protein) (HERV-W envelope protein) (Syncytin) (Syncytin-1) (Enverin) (Env-W) [Contains: Surface protein (SU) (gp50); Transmembrane protein (TM) (gp24)].

ENT1_HUMAN
θ value	0.279714 (rank : 8)	NC score	0.378069 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	P61550	Gene names
Domain Architecture	No domain graphic available
Description	HERV-T_19q13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-T Env protein) [Includes: Surface protein (SU); Transmembrane protein (TM)].

EDG5_MOUSE
θ value	1.06291 (rank : 9)	NC score	0.009616 (rank : 21)
Query Neighborhood Hits	17	Target Neighborhood Hits	721	Shared Neighborhood Hits	3
SwissProt Accessions	P52592, Q9R236	Gene names	Edg5, Gpcr13, Lpb2
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-5 (S1P receptor Edg-5) (Lysophospholipid receptor B2) (Endothelial differentiation G-protein coupled receptor 5) (Sphingosine 1-phosphate receptor 2) (S1P2).

ENR1_HUMAN
θ value	1.06291 (rank : 10)	NC score	0.252490 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q14264	Gene names	ERV3
Domain Architecture	No domain graphic available
Description	HERV-R_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (ERV3 envelope protein) (ERV-3 envelope protein) (HERV-R envelope protein) (ERV-R envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

CPT1B_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.017792 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q92523, Q13389, Q99655, Q9BY90	Gene names	CPT1B, KIAA1670
Domain Architecture
Description	Carnitine O-palmitoyltransferase I, muscle isoform (EC 2.3.1.21) (CPT I) (CPTI-M) (Carnitine palmitoyltransferase 1B) (Carnitine palmitoyltransferase I-like protein).

MDC1_HUMAN
θ value	1.81305 (rank : 12)	NC score	0.016852 (rank : 18)
Query Neighborhood Hits	17	Target Neighborhood Hits	1446	Shared Neighborhood Hits	8
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PAQR6_MOUSE
θ value	1.81305 (rank : 13)	NC score	0.021164 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q6TCG5, Q3UTT0, Q8CF56	Gene names	Paqr6
Domain Architecture	No domain graphic available
Description	Progestin and adipoQ receptor family member 6 (Progestin and adipoQ receptor family member VI).

LPP_HUMAN
θ value	3.0926 (rank : 14)	NC score	0.018154 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	775	Shared Neighborhood Hits	8
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

PO121_HUMAN
θ value	4.03905 (rank : 15)	NC score	0.043735 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	344	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

ZFHX2_HUMAN
θ value	4.03905 (rank : 16)	NC score	0.015452 (rank : 19)
Query Neighborhood Hits	17	Target Neighborhood Hits	1178	Shared Neighborhood Hits	7
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

MAP1B_HUMAN
θ value	5.27518 (rank : 17)	NC score	0.011928 (rank : 20)
Query Neighborhood Hits	17	Target Neighborhood Hits	903	Shared Neighborhood Hits	4
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

EFC1_HUMAN
θ value	θ > 10 (rank : 18)	NC score	0.326388 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	20	Shared Neighborhood Hits	7
SwissProt Accessions	P60507	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Fc1env) (HERV-Fc1env) [Contains: Surface protein (SU); Transmembrane protein (TM)].

EFC2_HUMAN
θ value	θ > 10 (rank : 19)	NC score	0.324066 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	P60608	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)2_7q36.2 provirus ancestral Env polyprotein (Envelope polyprotein) (Fc2deltaenv) [Includes: Surface protein (SU); Truncated transmembrane protein (TM)].

ENV2_MOUSE
θ value	θ > 10 (rank : 20)	NC score	0.340511 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	P11370, Q61529	Gene names	Fv4, Env
Domain Architecture
Description	Retrovirus-related Env polyprotein from Fv-4 locus.

ERB1_HUMAN
θ value	θ > 10 (rank : 21)	NC score	0.278431 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	P60509	Gene names
Domain Architecture	No domain graphic available
Description	HERV-R(b)_3p24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-R(b) Env protein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)].

Hits sorted by NC score

ENH4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q96L62	Gene names
Domain Architecture
Description	HERV-H_1q41 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-Hcl.7) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH5_HUMAN
NC score	0.997910 (rank : 2)	θ value	6.77497e-173 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	P61549	Gene names
Domain Architecture	No domain graphic available
Description	HERV-H_19p13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein RGH1) (Env protein RTLV-H) [Includes: Surface protein (SU)].

ENH3_HUMAN
NC score	0.952567 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	30	Shared Neighborhood Hits	13
SwissProt Accessions	Q9N2J8	Gene names
Domain Architecture
Description	HERV-H_2q24.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p59) (HERV-H/env59) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH2_HUMAN
NC score	0.942204 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q9N2J9	Gene names
Domain Architecture
Description	HERV-H_3q26 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p60) (HERV-H/env60) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH1_HUMAN
NC score	0.926625 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q9N2K0, O00354, Q96L63, Q9UNM3	Gene names
Domain Architecture
Description	HERV-H_2q24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p62) (Env protein HERV-H19) (HERV- H/env62) (Env protein HERV-Hcl.3) [Contains: Surface protein (SU); Transmembrane protein (TM)].

EFR1_HUMAN
NC score	0.787569 (rank : 6)	θ value	7.06379e-29 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P60508	Gene names	ERVFRDE1
Domain Architecture
Description	HERV-FRD_6p24.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-FRD) (Syncytin-2) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENW1_HUMAN
NC score	0.519549 (rank : 7)	θ value	0.0736092 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	22	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UQF0, O95244, O95245, Q8NHY7, Q9NRZ2, Q9NZG3	Gene names	ERVWE1
Domain Architecture
Description	HERV-W_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein gPr73) (HERV-7q Envelope protein) (HERV-W envelope protein) (Syncytin) (Syncytin-1) (Enverin) (Env-W) [Contains: Surface protein (SU) (gp50); Transmembrane protein (TM) (gp24)].

ENT1_HUMAN
NC score	0.378069 (rank : 8)	θ value	0.279714 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	P61550	Gene names
Domain Architecture	No domain graphic available
Description	HERV-T_19q13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-T Env protein) [Includes: Surface protein (SU); Transmembrane protein (TM)].

ENV2_MOUSE
NC score	0.340511 (rank : 9)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	17	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	P11370, Q61529	Gene names	Fv4, Env
Domain Architecture
Description	Retrovirus-related Env polyprotein from Fv-4 locus.

EFC1_HUMAN
NC score	0.326388 (rank : 10)	θ value	θ > 10 (rank : 18)
Query Neighborhood Hits	17	Target Neighborhood Hits	20	Shared Neighborhood Hits	7
SwissProt Accessions	P60507	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Fc1env) (HERV-Fc1env) [Contains: Surface protein (SU); Transmembrane protein (TM)].

EFC2_HUMAN
NC score	0.324066 (rank : 11)	θ value	θ > 10 (rank : 19)
Query Neighborhood Hits	17	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	P60608	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)2_7q36.2 provirus ancestral Env polyprotein (Envelope polyprotein) (Fc2deltaenv) [Includes: Surface protein (SU); Truncated transmembrane protein (TM)].

ERB1_HUMAN
NC score	0.278431 (rank : 12)	θ value	θ > 10 (rank : 21)
Query Neighborhood Hits	17	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	P60509	Gene names
Domain Architecture	No domain graphic available
Description	HERV-R(b)_3p24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-R(b) Env protein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)].

ENR1_HUMAN
NC score	0.252490 (rank : 13)	θ value	1.06291 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q14264	Gene names	ERV3
Domain Architecture	No domain graphic available
Description	HERV-R_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (ERV3 envelope protein) (ERV-3 envelope protein) (HERV-R envelope protein) (ERV-R envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

PO121_HUMAN
NC score	0.043735 (rank : 14)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	344	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PAQR6_MOUSE
NC score	0.021164 (rank : 15)	θ value	1.81305 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q6TCG5, Q3UTT0, Q8CF56	Gene names	Paqr6
Domain Architecture	No domain graphic available
Description	Progestin and adipoQ receptor family member 6 (Progestin and adipoQ receptor family member VI).

LPP_HUMAN
NC score	0.018154 (rank : 16)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	775	Shared Neighborhood Hits	8
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

CPT1B_HUMAN
NC score	0.017792 (rank : 17)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q92523, Q13389, Q99655, Q9BY90	Gene names	CPT1B, KIAA1670
Domain Architecture
Description	Carnitine O-palmitoyltransferase I, muscle isoform (EC 2.3.1.21) (CPT I) (CPTI-M) (Carnitine palmitoyltransferase 1B) (Carnitine palmitoyltransferase I-like protein).

MDC1_HUMAN
NC score	0.016852 (rank : 18)	θ value	1.81305 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	1446	Shared Neighborhood Hits	8
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

ZFHX2_HUMAN
NC score	0.015452 (rank : 19)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	1178	Shared Neighborhood Hits	7
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

MAP1B_HUMAN
NC score	0.011928 (rank : 20)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	903	Shared Neighborhood Hits	4
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

EDG5_MOUSE
NC score	0.009616 (rank : 21)	θ value	1.06291 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	721	Shared Neighborhood Hits	3
SwissProt Accessions	P52592, Q9R236	Gene names	Edg5, Gpcr13, Lpb2
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-5 (S1P receptor Edg-5) (Lysophospholipid receptor B2) (Endothelial differentiation G-protein coupled receptor 5) (Sphingosine 1-phosphate receptor 2) (S1P2).