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Network neighborhood for query Sequence : EFC1_HUMAN

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EFC1_HUMAN
SwissProt Accessions	P60507	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Fc1env) (HERV-Fc1env) [Contains: Surface protein (SU); Transmembrane protein (TM)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EFC1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	P60507	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Fc1env) (HERV-Fc1env) [Contains: Surface protein (SU); Transmembrane protein (TM)].

EFC2_HUMAN
θ value	2.00348e-116 (rank : 2)	NC score	0.966726 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	11
SwissProt Accessions	P60608	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)2_7q36.2 provirus ancestral Env polyprotein (Envelope polyprotein) (Fc2deltaenv) [Includes: Surface protein (SU); Truncated transmembrane protein (TM)].

ENW1_HUMAN
θ value	1.16434e-31 (rank : 3)	NC score	0.821260 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UQF0, O95244, O95245, Q8NHY7, Q9NRZ2, Q9NZG3	Gene names	ERVWE1
Domain Architecture
Description	HERV-W_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein gPr73) (HERV-7q Envelope protein) (HERV-W envelope protein) (Syncytin) (Syncytin-1) (Enverin) (Env-W) [Contains: Surface protein (SU) (gp50); Transmembrane protein (TM) (gp24)].

ENH1_HUMAN
θ value	2.35151e-24 (rank : 4)	NC score	0.616869 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q9N2K0, O00354, Q96L63, Q9UNM3	Gene names
Domain Architecture
Description	HERV-H_2q24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p62) (Env protein HERV-H19) (HERV- H/env62) (Env protein HERV-Hcl.3) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENV2_MOUSE
θ value	8.93572e-24 (rank : 5)	NC score	0.756341 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	P11370, Q61529	Gene names	Fv4, Env
Domain Architecture
Description	Retrovirus-related Env polyprotein from Fv-4 locus.

ENT1_HUMAN
θ value	2.43343e-21 (rank : 6)	NC score	0.743970 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	P61550	Gene names
Domain Architecture	No domain graphic available
Description	HERV-T_19q13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-T Env protein) [Includes: Surface protein (SU); Transmembrane protein (TM)].

ENH2_HUMAN
θ value	2.06002e-20 (rank : 7)	NC score	0.593769 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q9N2J9	Gene names
Domain Architecture
Description	HERV-H_3q26 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p60) (HERV-H/env60) [Contains: Surface protein (SU); Transmembrane protein (TM)].

EFR1_HUMAN
θ value	4.91457e-14 (rank : 8)	NC score	0.665301 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	P60508	Gene names	ERVFRDE1
Domain Architecture
Description	HERV-FRD_6p24.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-FRD) (Syncytin-2) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH3_HUMAN
θ value	7.84624e-12 (rank : 9)	NC score	0.555334 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q9N2J8	Gene names
Domain Architecture
Description	HERV-H_2q24.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p59) (HERV-H/env59) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ERB1_HUMAN
θ value	2.61198e-07 (rank : 10)	NC score	0.506779 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	23	Shared Neighborhood Hits	11
SwissProt Accessions	P60509	Gene names
Domain Architecture	No domain graphic available
Description	HERV-R(b)_3p24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-R(b) Env protein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)].

ENR1_HUMAN
θ value	0.0148317 (rank : 11)	NC score	0.331969 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q14264	Gene names	ERV3
Domain Architecture	No domain graphic available
Description	HERV-R_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (ERV3 envelope protein) (ERV-3 envelope protein) (HERV-R envelope protein) (ERV-R envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

AT8A1_MOUSE
θ value	2.36792 (rank : 12)	NC score	0.013597 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	P70704	Gene names	Atp8a1, Atpc1
Domain Architecture
Description	Probable phospholipid-transporting ATPase IA (EC 3.6.3.1) (Chromaffin granule ATPase II) (ATPase class I type 8A member 1).

NUP54_HUMAN
θ value	3.0926 (rank : 13)	NC score	0.025514 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z3B4, Q96EA7, Q9NVL5, Q9P0I1	Gene names	NUP54
Domain Architecture	No domain graphic available
Description	Nucleoporin p54 (54 kDa nucleoporin).

JADE1_MOUSE
θ value	4.03905 (rank : 14)	NC score	0.022708 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	160	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

SNTB1_MOUSE
θ value	4.03905 (rank : 15)	NC score	0.011007 (rank : 21)
Query Neighborhood Hits	20	Target Neighborhood Hits	160	Shared Neighborhood Hits	2
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

JADE1_HUMAN
θ value	5.27518 (rank : 16)	NC score	0.022003 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	140	Shared Neighborhood Hits	5
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

AT8A1_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.011536 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2Q0	Gene names	ATP8A1, ATPIA
Domain Architecture
Description	Probable phospholipid-transporting ATPase IA (EC 3.6.3.1) (Chromaffin granule ATPase II) (ATPase class I type 8A member 1).

JADE2_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.020581 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	199	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE2_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.018310 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	560	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

RNAS2_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.010507 (rank : 22)
Query Neighborhood Hits	20	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P10153, Q9H2B7, Q9UCG7	Gene names	RNASE2, EDN, RNS2
Domain Architecture
Description	Nonsecretory ribonuclease precursor (EC 3.1.27.5) (Ribonuclease US) (Eosinophil-derived neurotoxin) (RNase UpI-2) (Ribonuclease 2) (RNase 2).

ENH4_HUMAN
θ value	θ > 10 (rank : 21)	NC score	0.326388 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q96L62	Gene names
Domain Architecture
Description	HERV-H_1q41 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-Hcl.7) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH5_HUMAN
θ value	θ > 10 (rank : 22)	NC score	0.321181 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P61549	Gene names
Domain Architecture	No domain graphic available
Description	HERV-H_19p13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein RGH1) (Env protein RTLV-H) [Includes: Surface protein (SU)].

Hits sorted by NC score

EFC1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	P60507	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Fc1env) (HERV-Fc1env) [Contains: Surface protein (SU); Transmembrane protein (TM)].

EFC2_HUMAN
NC score	0.966726 (rank : 2)	θ value	2.00348e-116 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	11
SwissProt Accessions	P60608	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)2_7q36.2 provirus ancestral Env polyprotein (Envelope polyprotein) (Fc2deltaenv) [Includes: Surface protein (SU); Truncated transmembrane protein (TM)].

ENW1_HUMAN
NC score	0.821260 (rank : 3)	θ value	1.16434e-31 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UQF0, O95244, O95245, Q8NHY7, Q9NRZ2, Q9NZG3	Gene names	ERVWE1
Domain Architecture
Description	HERV-W_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein gPr73) (HERV-7q Envelope protein) (HERV-W envelope protein) (Syncytin) (Syncytin-1) (Enverin) (Env-W) [Contains: Surface protein (SU) (gp50); Transmembrane protein (TM) (gp24)].

ENV2_MOUSE
NC score	0.756341 (rank : 4)	θ value	8.93572e-24 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	P11370, Q61529	Gene names	Fv4, Env
Domain Architecture
Description	Retrovirus-related Env polyprotein from Fv-4 locus.

ENT1_HUMAN
NC score	0.743970 (rank : 5)	θ value	2.43343e-21 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	P61550	Gene names
Domain Architecture	No domain graphic available
Description	HERV-T_19q13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-T Env protein) [Includes: Surface protein (SU); Transmembrane protein (TM)].

EFR1_HUMAN
NC score	0.665301 (rank : 6)	θ value	4.91457e-14 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	P60508	Gene names	ERVFRDE1
Domain Architecture
Description	HERV-FRD_6p24.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-FRD) (Syncytin-2) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH1_HUMAN
NC score	0.616869 (rank : 7)	θ value	2.35151e-24 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q9N2K0, O00354, Q96L63, Q9UNM3	Gene names
Domain Architecture
Description	HERV-H_2q24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p62) (Env protein HERV-H19) (HERV- H/env62) (Env protein HERV-Hcl.3) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH2_HUMAN
NC score	0.593769 (rank : 8)	θ value	2.06002e-20 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q9N2J9	Gene names
Domain Architecture
Description	HERV-H_3q26 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p60) (HERV-H/env60) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH3_HUMAN
NC score	0.555334 (rank : 9)	θ value	7.84624e-12 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q9N2J8	Gene names
Domain Architecture
Description	HERV-H_2q24.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p59) (HERV-H/env59) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ERB1_HUMAN
NC score	0.506779 (rank : 10)	θ value	2.61198e-07 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	23	Shared Neighborhood Hits	11
SwissProt Accessions	P60509	Gene names
Domain Architecture	No domain graphic available
Description	HERV-R(b)_3p24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-R(b) Env protein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)].

ENR1_HUMAN
NC score	0.331969 (rank : 11)	θ value	0.0148317 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q14264	Gene names	ERV3
Domain Architecture	No domain graphic available
Description	HERV-R_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (ERV3 envelope protein) (ERV-3 envelope protein) (HERV-R envelope protein) (ERV-R envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH4_HUMAN
NC score	0.326388 (rank : 12)	θ value	θ > 10 (rank : 21)
Query Neighborhood Hits	20	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q96L62	Gene names
Domain Architecture
Description	HERV-H_1q41 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-Hcl.7) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH5_HUMAN
NC score	0.321181 (rank : 13)	θ value	θ > 10 (rank : 22)
Query Neighborhood Hits	20	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P61549	Gene names
Domain Architecture	No domain graphic available
Description	HERV-H_19p13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein RGH1) (Env protein RTLV-H) [Includes: Surface protein (SU)].

NUP54_HUMAN
NC score	0.025514 (rank : 14)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z3B4, Q96EA7, Q9NVL5, Q9P0I1	Gene names	NUP54
Domain Architecture	No domain graphic available
Description	Nucleoporin p54 (54 kDa nucleoporin).

JADE1_MOUSE
NC score	0.022708 (rank : 15)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	160	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_HUMAN
NC score	0.022003 (rank : 16)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	140	Shared Neighborhood Hits	5
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE2_HUMAN
NC score	0.020581 (rank : 17)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	199	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE2_MOUSE
NC score	0.018310 (rank : 18)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	560	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

AT8A1_MOUSE
NC score	0.013597 (rank : 19)	θ value	2.36792 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	P70704	Gene names	Atp8a1, Atpc1
Domain Architecture
Description	Probable phospholipid-transporting ATPase IA (EC 3.6.3.1) (Chromaffin granule ATPase II) (ATPase class I type 8A member 1).

AT8A1_HUMAN
NC score	0.011536 (rank : 20)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2Q0	Gene names	ATP8A1, ATPIA
Domain Architecture
Description	Probable phospholipid-transporting ATPase IA (EC 3.6.3.1) (Chromaffin granule ATPase II) (ATPase class I type 8A member 1).

SNTB1_MOUSE
NC score	0.011007 (rank : 21)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	160	Shared Neighborhood Hits	2
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

RNAS2_HUMAN
NC score	0.010507 (rank : 22)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P10153, Q9H2B7, Q9UCG7	Gene names	RNASE2, EDN, RNS2
Domain Architecture
Description	Nonsecretory ribonuclease precursor (EC 3.1.27.5) (Ribonuclease US) (Eosinophil-derived neurotoxin) (RNase UpI-2) (Ribonuclease 2) (RNase 2).