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Network neighborhood for query Sequence : EFC2_HUMAN

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EFC2_HUMAN
SwissProt Accessions	P60608	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)2_7q36.2 provirus ancestral Env polyprotein (Envelope polyprotein) (Fc2deltaenv) [Includes: Surface protein (SU); Truncated transmembrane protein (TM)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EFC2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	P60608	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)2_7q36.2 provirus ancestral Env polyprotein (Envelope polyprotein) (Fc2deltaenv) [Includes: Surface protein (SU); Truncated transmembrane protein (TM)].

EFC1_HUMAN
θ value	2.00348e-116 (rank : 2)	NC score	0.966726 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	20	Shared Neighborhood Hits	11
SwissProt Accessions	P60507	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Fc1env) (HERV-Fc1env) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENW1_HUMAN
θ value	3.07116e-24 (rank : 3)	NC score	0.788975 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UQF0, O95244, O95245, Q8NHY7, Q9NRZ2, Q9NZG3	Gene names	ERVWE1
Domain Architecture
Description	HERV-W_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein gPr73) (HERV-7q Envelope protein) (HERV-W envelope protein) (Syncytin) (Syncytin-1) (Enverin) (Env-W) [Contains: Surface protein (SU) (gp50); Transmembrane protein (TM) (gp24)].

ENH1_HUMAN
θ value	5.42112e-21 (rank : 4)	NC score	0.601002 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q9N2K0, O00354, Q96L63, Q9UNM3	Gene names
Domain Architecture
Description	HERV-H_2q24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p62) (Env protein HERV-H19) (HERV- H/env62) (Env protein HERV-Hcl.3) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH2_HUMAN
θ value	2.5182e-18 (rank : 5)	NC score	0.581124 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q9N2J9	Gene names
Domain Architecture
Description	HERV-H_3q26 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p60) (HERV-H/env60) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENV2_MOUSE
θ value	1.68911e-14 (rank : 6)	NC score	0.696522 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	P11370, Q61529	Gene names	Fv4, Env
Domain Architecture
Description	Retrovirus-related Env polyprotein from Fv-4 locus.

EFR1_HUMAN
θ value	6.00763e-12 (rank : 7)	NC score	0.642305 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	P60508	Gene names	ERVFRDE1
Domain Architecture
Description	HERV-FRD_6p24.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-FRD) (Syncytin-2) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENT1_HUMAN
θ value	1.02475e-11 (rank : 8)	NC score	0.678299 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	P61550	Gene names
Domain Architecture	No domain graphic available
Description	HERV-T_19q13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-T Env protein) [Includes: Surface protein (SU); Transmembrane protein (TM)].

ENH3_HUMAN
θ value	2.98157e-11 (rank : 9)	NC score	0.542149 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q9N2J8	Gene names
Domain Architecture
Description	HERV-H_2q24.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p59) (HERV-H/env59) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ERB1_HUMAN
θ value	3.19293e-05 (rank : 10)	NC score	0.477140 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	23	Shared Neighborhood Hits	11
SwissProt Accessions	P60509	Gene names
Domain Architecture	No domain graphic available
Description	HERV-R(b)_3p24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-R(b) Env protein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)].

ENR1_HUMAN
θ value	0.0252991 (rank : 11)	NC score	0.321614 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q14264	Gene names	ERV3
Domain Architecture	No domain graphic available
Description	HERV-R_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (ERV3 envelope protein) (ERV-3 envelope protein) (HERV-R envelope protein) (ERV-R envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

SNTB1_HUMAN
θ value	3.0926 (rank : 12)	NC score	0.013165 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	157	Shared Neighborhood Hits	2
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

GP112_HUMAN
θ value	4.03905 (rank : 13)	NC score	0.010012 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	441	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

TSH1_HUMAN
θ value	4.03905 (rank : 14)	NC score	0.011832 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	558	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZSZ6, O60534, Q4LE29, Q53EU4	Gene names	TSHZ1, SDCCAG33, TSH1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3) (Antigen NY-CO-33).

CS007_HUMAN
θ value	6.88961 (rank : 15)	NC score	0.017265 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	401	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CS007_MOUSE
θ value	6.88961 (rank : 16)	NC score	0.017466 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	464	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

IF4G1_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.010219 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	347	Shared Neighborhood Hits	3
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

NKX61_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.005294 (rank : 21)
Query Neighborhood Hits	19	Target Neighborhood Hits	431	Shared Neighborhood Hits	3
SwissProt Accessions	P78426	Gene names	NKX6-1, NKX6A
Domain Architecture
Description	Homeobox protein Nkx-6.1.

NKX61_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.005376 (rank : 20)
Query Neighborhood Hits	19	Target Neighborhood Hits	439	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

ENH4_HUMAN
θ value	θ > 10 (rank : 20)	NC score	0.324066 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q96L62	Gene names
Domain Architecture
Description	HERV-H_1q41 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-Hcl.7) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH5_HUMAN
θ value	θ > 10 (rank : 21)	NC score	0.320244 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P61549	Gene names
Domain Architecture	No domain graphic available
Description	HERV-H_19p13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein RGH1) (Env protein RTLV-H) [Includes: Surface protein (SU)].

Hits sorted by NC score

EFC2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	P60608	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)2_7q36.2 provirus ancestral Env polyprotein (Envelope polyprotein) (Fc2deltaenv) [Includes: Surface protein (SU); Truncated transmembrane protein (TM)].

EFC1_HUMAN
NC score	0.966726 (rank : 2)	θ value	2.00348e-116 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	20	Shared Neighborhood Hits	11
SwissProt Accessions	P60507	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Fc1env) (HERV-Fc1env) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENW1_HUMAN
NC score	0.788975 (rank : 3)	θ value	3.07116e-24 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UQF0, O95244, O95245, Q8NHY7, Q9NRZ2, Q9NZG3	Gene names	ERVWE1
Domain Architecture
Description	HERV-W_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein gPr73) (HERV-7q Envelope protein) (HERV-W envelope protein) (Syncytin) (Syncytin-1) (Enverin) (Env-W) [Contains: Surface protein (SU) (gp50); Transmembrane protein (TM) (gp24)].

ENV2_MOUSE
NC score	0.696522 (rank : 4)	θ value	1.68911e-14 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	P11370, Q61529	Gene names	Fv4, Env
Domain Architecture
Description	Retrovirus-related Env polyprotein from Fv-4 locus.

ENT1_HUMAN
NC score	0.678299 (rank : 5)	θ value	1.02475e-11 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	P61550	Gene names
Domain Architecture	No domain graphic available
Description	HERV-T_19q13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-T Env protein) [Includes: Surface protein (SU); Transmembrane protein (TM)].

EFR1_HUMAN
NC score	0.642305 (rank : 6)	θ value	6.00763e-12 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	P60508	Gene names	ERVFRDE1
Domain Architecture
Description	HERV-FRD_6p24.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-FRD) (Syncytin-2) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH1_HUMAN
NC score	0.601002 (rank : 7)	θ value	5.42112e-21 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q9N2K0, O00354, Q96L63, Q9UNM3	Gene names
Domain Architecture
Description	HERV-H_2q24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p62) (Env protein HERV-H19) (HERV- H/env62) (Env protein HERV-Hcl.3) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH2_HUMAN
NC score	0.581124 (rank : 8)	θ value	2.5182e-18 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q9N2J9	Gene names
Domain Architecture
Description	HERV-H_3q26 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p60) (HERV-H/env60) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH3_HUMAN
NC score	0.542149 (rank : 9)	θ value	2.98157e-11 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q9N2J8	Gene names
Domain Architecture
Description	HERV-H_2q24.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p59) (HERV-H/env59) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ERB1_HUMAN
NC score	0.477140 (rank : 10)	θ value	3.19293e-05 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	23	Shared Neighborhood Hits	11
SwissProt Accessions	P60509	Gene names
Domain Architecture	No domain graphic available
Description	HERV-R(b)_3p24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-R(b) Env protein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)].

ENH4_HUMAN
NC score	0.324066 (rank : 11)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	19	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q96L62	Gene names
Domain Architecture
Description	HERV-H_1q41 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-Hcl.7) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENR1_HUMAN
NC score	0.321614 (rank : 12)	θ value	0.0252991 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q14264	Gene names	ERV3
Domain Architecture	No domain graphic available
Description	HERV-R_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (ERV3 envelope protein) (ERV-3 envelope protein) (HERV-R envelope protein) (ERV-R envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH5_HUMAN
NC score	0.320244 (rank : 13)	θ value	θ > 10 (rank : 21)
Query Neighborhood Hits	19	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P61549	Gene names
Domain Architecture	No domain graphic available
Description	HERV-H_19p13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein RGH1) (Env protein RTLV-H) [Includes: Surface protein (SU)].

CS007_MOUSE
NC score	0.017466 (rank : 14)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	464	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

CS007_HUMAN
NC score	0.017265 (rank : 15)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	401	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

SNTB1_HUMAN
NC score	0.013165 (rank : 16)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	157	Shared Neighborhood Hits	2
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

TSH1_HUMAN
NC score	0.011832 (rank : 17)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	558	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZSZ6, O60534, Q4LE29, Q53EU4	Gene names	TSHZ1, SDCCAG33, TSH1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3) (Antigen NY-CO-33).

IF4G1_HUMAN
NC score	0.010219 (rank : 18)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	347	Shared Neighborhood Hits	3
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

GP112_HUMAN
NC score	0.010012 (rank : 19)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	441	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

NKX61_MOUSE
NC score	0.005376 (rank : 20)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	439	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

NKX61_HUMAN
NC score	0.005294 (rank : 21)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	431	Shared Neighborhood Hits	3
SwissProt Accessions	P78426	Gene names	NKX6-1, NKX6A
Domain Architecture
Description	Homeobox protein Nkx-6.1.