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Network neighborhood for query Sequence : DDX11_MOUSE

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DDX11_MOUSE
SwissProt Accessions	Q6AXC6	Gene names	Ddx11
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX11 (EC 3.6.1.-) (DEAD/H box protein 11).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DDX11_HUMAN
θ value	0 (rank : 1)	NC score	0.966030 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	124	Shared Neighborhood Hits	14
SwissProt Accessions	Q96FC9, Q13333, Q86VQ4, Q86W62, Q92498, Q92770, Q92998, Q92999	Gene names	DDX11, CHL1, CHLR1, KRG2
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX11 (EC 3.6.1.-) (DEAD/H box protein 11) (CHL1 homolog) (Keratinocyte growth factor-regulated gene 2 protein) (KRG-2).

DDX11_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q6AXC6	Gene names	Ddx11
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX11 (EC 3.6.1.-) (DEAD/H box protein 11).

FANCJ_MOUSE
θ value	2.92676e-75 (rank : 3)	NC score	0.852179 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	57	Shared Neighborhood Hits	8
SwissProt Accessions	Q5SXJ3, Q8BJQ8, Q8BKI6	Gene names	Brip1, Bach1, Fancj
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

FANCJ_HUMAN
θ value	5.51964e-74 (rank : 4)	NC score	0.855942 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	72	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BX63, Q8NCI5	Gene names	BRIP1, BACH1, FANCJ
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

RTEL1_HUMAN
θ value	2.84138e-62 (rank : 5)	NC score	0.842785 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZ71, Q5JTV4, Q9BW37, Q9H402, Q9H4X6, Q9NX25, Q9NZ73, Q9UPR4, Q9Y4R6	Gene names	RTEL1, C20orf41, KIAA1088, NHL
Domain Architecture
Description	Regulator of telomere elongation helicase 1 (EC 3.6.1.-) (Helicase- like protein NHL).

ERCC2_MOUSE
θ value	9.83387e-39 (rank : 6)	NC score	0.781679 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	25	Shared Neighborhood Hits	7
SwissProt Accessions	O08811, Q9DC01	Gene names	Ercc2, Xpd
Domain Architecture
Description	TFIIH basal transcription factor complex helicase subunit (EC 3.6.1.-) (DNA-repair protein complementing XP-D cells) (Xeroderma pigmentosum group D-complementing protein) (CXPD) (DNA excision repair protein ERCC-2).

ERCC2_HUMAN
θ value	2.19075e-38 (rank : 7)	NC score	0.779825 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	21	Shared Neighborhood Hits	7
SwissProt Accessions	P18074, Q8N721	Gene names	ERCC2, XPD, XPDC
Domain Architecture
Description	TFIIH basal transcription factor complex helicase subunit (EC 3.6.1.-) (DNA-repair protein complementing XP-D cells) (Xeroderma pigmentosum group D-complementing protein) (CXPD) (DNA excision repair protein ERCC-2).

BFSP2_MOUSE
θ value	0.0431538 (rank : 8)	NC score	0.033253 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	423	Shared Neighborhood Hits	15
SwissProt Accessions	Q6NVD9, Q63832, Q6P5N4, Q8VDD6	Gene names	Bfsp2
Domain Architecture	No domain graphic available
Description	Phakinin (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 49) (CP49) (49 kDa cytoskeletal protein).

STK10_HUMAN
θ value	0.0736092 (rank : 9)	NC score	0.020118 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	1921	Shared Neighborhood Hits	19
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

MY18A_HUMAN
θ value	0.0961366 (rank : 10)	NC score	0.025500 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	1929	Shared Neighborhood Hits	22
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_MOUSE
θ value	0.0961366 (rank : 11)	NC score	0.027293 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	1989	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TBCD2_HUMAN
θ value	0.0961366 (rank : 12)	NC score	0.045079 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	419	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

STK10_MOUSE
θ value	0.163984 (rank : 13)	NC score	0.020572 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	2132	Shared Neighborhood Hits	19
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

AZI1_MOUSE
θ value	0.279714 (rank : 14)	NC score	0.050906 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	990	Shared Neighborhood Hits	22
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

BFSP2_HUMAN
θ value	0.365318 (rank : 15)	NC score	0.025849 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	348	Shared Neighborhood Hits	13
SwissProt Accessions	Q13515, Q9HBW5	Gene names	BFSP2
Domain Architecture
Description	Phakinin (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 49) (CP49) (49 kDa cytoskeletal protein) (CP 47) (CP47) (Lens intermediate filament-like light) (LIFL-L).

SLK_HUMAN
θ value	0.365318 (rank : 16)	NC score	0.016634 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	1775	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

CDYL_MOUSE
θ value	0.62314 (rank : 17)	NC score	0.021077 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WTK2	Gene names	Cdyl
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

FBX3_HUMAN
θ value	1.06291 (rank : 18)	NC score	0.031987 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UK99, Q9NUX2	Gene names	FBXO3, FBX3
Domain Architecture
Description	F-box only protein 3.

NFAT5_MOUSE
θ value	1.06291 (rank : 19)	NC score	0.025319 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

REST_HUMAN
θ value	1.06291 (rank : 20)	NC score	0.022741 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	1605	Shared Neighborhood Hits	23
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

SLK_MOUSE
θ value	1.06291 (rank : 21)	NC score	0.014378 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	1798	Shared Neighborhood Hits	22
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

DMD_MOUSE
θ value	1.38821 (rank : 22)	NC score	0.022001 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	1111	Shared Neighborhood Hits	18
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

GOGA4_MOUSE
θ value	1.81305 (rank : 23)	NC score	0.021517 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	1939	Shared Neighborhood Hits	23
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

EST1A_MOUSE
θ value	2.36792 (rank : 24)	NC score	0.019595 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	138	Shared Neighborhood Hits	2
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

DMD_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.022352 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	1135	Shared Neighborhood Hits	19
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

IL6RA_MOUSE
θ value	3.0926 (rank : 26)	NC score	0.016914 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	104	Shared Neighborhood Hits	2
SwissProt Accessions	P22272	Gene names	Il6ra, Il6r
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (CD126 antigen).

NALP5_MOUSE
θ value	3.0926 (rank : 27)	NC score	0.009196 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	560	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

TRIM8_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.013138 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	650	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

REST_MOUSE
θ value	4.03905 (rank : 29)	NC score	0.020579 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	1506	Shared Neighborhood Hits	21
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

DYH5_MOUSE
θ value	5.27518 (rank : 30)	NC score	0.011453 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	286	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHE6, Q8BWG1	Gene names	Dnah5, Dnahc5
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (Mdnah5).

EP15_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.015202 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	1021	Shared Neighborhood Hits	19
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

CC062_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.016881 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZUJ4, Q6P7E9, Q7Z3X6	Gene names	C3orf62
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf62.

DEN2D_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.007805 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H6A0, Q5T5V6, Q9BSU0	Gene names	DENND2D
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2D.

NFAT5_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.023027 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	217	Shared Neighborhood Hits	4
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

ROCK1_MOUSE
θ value	6.88961 (rank : 35)	NC score	0.009107 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	2126	Shared Neighborhood Hits	22
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

TRI62_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.008222 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	584	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

ATBF1_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.004369 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	1841	Shared Neighborhood Hits	13
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

BIG2_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.006770 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

LRBA_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.006321 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	196	Shared Neighborhood Hits	4
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

MRCKG_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.007419 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	1466	Shared Neighborhood Hits	19
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

Hits sorted by NC score

DDX11_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q6AXC6	Gene names	Ddx11
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX11 (EC 3.6.1.-) (DEAD/H box protein 11).

DDX11_HUMAN
NC score	0.966030 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	124	Shared Neighborhood Hits	14
SwissProt Accessions	Q96FC9, Q13333, Q86VQ4, Q86W62, Q92498, Q92770, Q92998, Q92999	Gene names	DDX11, CHL1, CHLR1, KRG2
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX11 (EC 3.6.1.-) (DEAD/H box protein 11) (CHL1 homolog) (Keratinocyte growth factor-regulated gene 2 protein) (KRG-2).

FANCJ_HUMAN
NC score	0.855942 (rank : 3)	θ value	5.51964e-74 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	72	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BX63, Q8NCI5	Gene names	BRIP1, BACH1, FANCJ
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

FANCJ_MOUSE
NC score	0.852179 (rank : 4)	θ value	2.92676e-75 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	57	Shared Neighborhood Hits	8
SwissProt Accessions	Q5SXJ3, Q8BJQ8, Q8BKI6	Gene names	Brip1, Bach1, Fancj
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

RTEL1_HUMAN
NC score	0.842785 (rank : 5)	θ value	2.84138e-62 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZ71, Q5JTV4, Q9BW37, Q9H402, Q9H4X6, Q9NX25, Q9NZ73, Q9UPR4, Q9Y4R6	Gene names	RTEL1, C20orf41, KIAA1088, NHL
Domain Architecture
Description	Regulator of telomere elongation helicase 1 (EC 3.6.1.-) (Helicase- like protein NHL).

ERCC2_MOUSE
NC score	0.781679 (rank : 6)	θ value	9.83387e-39 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	25	Shared Neighborhood Hits	7
SwissProt Accessions	O08811, Q9DC01	Gene names	Ercc2, Xpd
Domain Architecture
Description	TFIIH basal transcription factor complex helicase subunit (EC 3.6.1.-) (DNA-repair protein complementing XP-D cells) (Xeroderma pigmentosum group D-complementing protein) (CXPD) (DNA excision repair protein ERCC-2).

ERCC2_HUMAN
NC score	0.779825 (rank : 7)	θ value	2.19075e-38 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	21	Shared Neighborhood Hits	7
SwissProt Accessions	P18074, Q8N721	Gene names	ERCC2, XPD, XPDC
Domain Architecture
Description	TFIIH basal transcription factor complex helicase subunit (EC 3.6.1.-) (DNA-repair protein complementing XP-D cells) (Xeroderma pigmentosum group D-complementing protein) (CXPD) (DNA excision repair protein ERCC-2).

AZI1_MOUSE
NC score	0.050906 (rank : 8)	θ value	0.279714 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	990	Shared Neighborhood Hits	22
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

TBCD2_HUMAN
NC score	0.045079 (rank : 9)	θ value	0.0961366 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	419	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

BFSP2_MOUSE
NC score	0.033253 (rank : 10)	θ value	0.0431538 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	423	Shared Neighborhood Hits	15
SwissProt Accessions	Q6NVD9, Q63832, Q6P5N4, Q8VDD6	Gene names	Bfsp2
Domain Architecture	No domain graphic available
Description	Phakinin (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 49) (CP49) (49 kDa cytoskeletal protein).

FBX3_HUMAN
NC score	0.031987 (rank : 11)	θ value	1.06291 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UK99, Q9NUX2	Gene names	FBXO3, FBX3
Domain Architecture
Description	F-box only protein 3.

MY18A_MOUSE
NC score	0.027293 (rank : 12)	θ value	0.0961366 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	1989	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

BFSP2_HUMAN
NC score	0.025849 (rank : 13)	θ value	0.365318 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	348	Shared Neighborhood Hits	13
SwissProt Accessions	Q13515, Q9HBW5	Gene names	BFSP2
Domain Architecture
Description	Phakinin (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 49) (CP49) (49 kDa cytoskeletal protein) (CP 47) (CP47) (Lens intermediate filament-like light) (LIFL-L).

MY18A_HUMAN
NC score	0.025500 (rank : 14)	θ value	0.0961366 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	1929	Shared Neighborhood Hits	22
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NFAT5_MOUSE
NC score	0.025319 (rank : 15)	θ value	1.06291 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

NFAT5_HUMAN
NC score	0.023027 (rank : 16)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	217	Shared Neighborhood Hits	4
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

REST_HUMAN
NC score	0.022741 (rank : 17)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	1605	Shared Neighborhood Hits	23
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

DMD_HUMAN
NC score	0.022352 (rank : 18)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	1135	Shared Neighborhood Hits	19
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DMD_MOUSE
NC score	0.022001 (rank : 19)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	1111	Shared Neighborhood Hits	18
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

GOGA4_MOUSE
NC score	0.021517 (rank : 20)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	1939	Shared Neighborhood Hits	23
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

CDYL_MOUSE
NC score	0.021077 (rank : 21)	θ value	0.62314 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WTK2	Gene names	Cdyl
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

REST_MOUSE
NC score	0.020579 (rank : 22)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	1506	Shared Neighborhood Hits	21
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

STK10_MOUSE
NC score	0.020572 (rank : 23)	θ value	0.163984 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	2132	Shared Neighborhood Hits	19
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

STK10_HUMAN
NC score	0.020118 (rank : 24)	θ value	0.0736092 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	1921	Shared Neighborhood Hits	19
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

EST1A_MOUSE
NC score	0.019595 (rank : 25)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	138	Shared Neighborhood Hits	2
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

IL6RA_MOUSE
NC score	0.016914 (rank : 26)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	104	Shared Neighborhood Hits	2
SwissProt Accessions	P22272	Gene names	Il6ra, Il6r
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (CD126 antigen).

CC062_HUMAN
NC score	0.016881 (rank : 27)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZUJ4, Q6P7E9, Q7Z3X6	Gene names	C3orf62
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf62.

SLK_HUMAN
NC score	0.016634 (rank : 28)	θ value	0.365318 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	1775	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

EP15_HUMAN
NC score	0.015202 (rank : 29)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	1021	Shared Neighborhood Hits	19
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

SLK_MOUSE
NC score	0.014378 (rank : 30)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	1798	Shared Neighborhood Hits	22
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

TRIM8_HUMAN
NC score	0.013138 (rank : 31)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	650	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

DYH5_MOUSE
NC score	0.011453 (rank : 32)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	286	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHE6, Q8BWG1	Gene names	Dnah5, Dnahc5
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (Mdnah5).

NALP5_MOUSE
NC score	0.009196 (rank : 33)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	560	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

ROCK1_MOUSE
NC score	0.009107 (rank : 34)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	2126	Shared Neighborhood Hits	22
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

TRI62_HUMAN
NC score	0.008222 (rank : 35)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	584	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

DEN2D_HUMAN
NC score	0.007805 (rank : 36)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H6A0, Q5T5V6, Q9BSU0	Gene names	DENND2D
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2D.

MRCKG_MOUSE
NC score	0.007419 (rank : 37)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	1466	Shared Neighborhood Hits	19
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

BIG2_HUMAN
NC score	0.006770 (rank : 38)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

LRBA_HUMAN
NC score	0.006321 (rank : 39)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	196	Shared Neighborhood Hits	4
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

ATBF1_MOUSE
NC score	0.004369 (rank : 40)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	1841	Shared Neighborhood Hits	13
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).