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Network neighborhood for query Sequence : CHKA_HUMAN

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CHKA_HUMAN
SwissProt Accessions	P35790, Q8NE29	Gene names	CHKA, CHK, CKI
Domain Architecture
Description	Choline kinase alpha (EC 2.7.1.32) (CK) (CHETK-alpha).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CHKA_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	P35790, Q8NE29	Gene names	CHKA, CHK, CKI
Domain Architecture
Description	Choline kinase alpha (EC 2.7.1.32) (CK) (CHETK-alpha).

CHKA_MOUSE
θ value	0 (rank : 2)	NC score	0.996544 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	O54804, Q8BPL3, Q8BPW6, Q9CXP3, Q9QX56	Gene names	Chka, Chk
Domain Architecture
Description	Choline kinase alpha (EC 2.7.1.32) (CK) (CHETK-alpha).

CHKB_HUMAN
θ value	9.92011e-124 (rank : 3)	NC score	0.982669 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y259, Q13388	Gene names	CHKB, CHETK, CHKL
Domain Architecture
Description	Choline/ethanolamine kinase [Includes: Choline kinase beta (EC 2.7.1.32) (CK); Ethanolamine kinase (EC 2.7.1.82) (EK)].

CHKB_MOUSE
θ value	2.89301e-115 (rank : 4)	NC score	0.981566 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	O55229	Gene names	Chkb, Chetk, Chkl
Domain Architecture
Description	Choline/ethanolamine kinase [Includes: Choline kinase beta (EC 2.7.1.32) (CK); Ethanolamine kinase (EC 2.7.1.82) (EK)].

EKI1_HUMAN
θ value	1.01765e-35 (rank : 5)	NC score	0.836633 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HBU6	Gene names	ETNK1, EKI1
Domain Architecture
Description	Ethanolamine kinase 1 (EC 2.7.1.82) (EKI 1).

EKI2_HUMAN
θ value	7.32683e-18 (rank : 6)	NC score	0.747790 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NVF9	Gene names	ETNK2, EKI2
Domain Architecture
Description	Ethanolamine kinase 2 (EC 2.7.1.82) (EKI 2) (Ethanolamine kinase-like protein).

PMYT1_MOUSE
θ value	0.279714 (rank : 7)	NC score	0.006983 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	910	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ESG9, Q8R3L4	Gene names	Pkmyt1, Myt1
Domain Architecture	No domain graphic available
Description	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase).

RBM6_HUMAN
θ value	0.279714 (rank : 8)	NC score	0.042667 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	221	Shared Neighborhood Hits	3
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

AATK_HUMAN
θ value	1.38821 (rank : 9)	NC score	0.005041 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	1243	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

RP3A_MOUSE
θ value	1.38821 (rank : 10)	NC score	0.013000 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	510	Shared Neighborhood Hits	10
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

TS1R3_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.019315 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q7RTX0, Q5TA49, Q8NGW9	Gene names	TAS1R3, T1R3, TR3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3).

ZN710_HUMAN
θ value	2.36792 (rank : 12)	NC score	0.000684 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	796	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N1W2, Q6ZMK9, Q8NDU0	Gene names	ZNF710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.

SON_HUMAN
θ value	3.0926 (rank : 13)	NC score	0.009198 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	1568	Shared Neighborhood Hits	10
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

MTMR3_MOUSE
θ value	5.27518 (rank : 14)	NC score	0.009113 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	78	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K296	Gene names	Mtmr3
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48).

PCLO_MOUSE
θ value	5.27518 (rank : 15)	NC score	0.007610 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	2275	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PSL1_HUMAN
θ value	5.27518 (rank : 16)	NC score	0.012030 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	650	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

ALEX_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.015633 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	361	Shared Neighborhood Hits	6
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

TLK1_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.002111 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	967	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKI8, Q14150, Q8N591, Q9NYH2, Q9Y4F6	Gene names	TLK1, KIAA0137
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1) (PKU-beta).

TLK1_MOUSE
θ value	6.88961 (rank : 19)	NC score	0.002123 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	947	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C0V0	Gene names	Tlk1
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1).

BAI2_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.005725 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	332	Shared Neighborhood Hits	4
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
θ value	8.99809 (rank : 21)	NC score	0.005683 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	323	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

CBP_MOUSE
θ value	8.99809 (rank : 22)	NC score	0.006991 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	1051	Shared Neighborhood Hits	8
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

IF4B_MOUSE
θ value	8.99809 (rank : 23)	NC score	0.008690 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	368	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

RGS3_MOUSE
θ value	8.99809 (rank : 24)	NC score	0.004273 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	1621	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TENS4_MOUSE
θ value	8.99809 (rank : 25)	NC score	0.009784 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	225	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

Hits sorted by NC score

CHKA_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	P35790, Q8NE29	Gene names	CHKA, CHK, CKI
Domain Architecture
Description	Choline kinase alpha (EC 2.7.1.32) (CK) (CHETK-alpha).

CHKA_MOUSE
NC score	0.996544 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	O54804, Q8BPL3, Q8BPW6, Q9CXP3, Q9QX56	Gene names	Chka, Chk
Domain Architecture
Description	Choline kinase alpha (EC 2.7.1.32) (CK) (CHETK-alpha).

CHKB_HUMAN
NC score	0.982669 (rank : 3)	θ value	9.92011e-124 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y259, Q13388	Gene names	CHKB, CHETK, CHKL
Domain Architecture
Description	Choline/ethanolamine kinase [Includes: Choline kinase beta (EC 2.7.1.32) (CK); Ethanolamine kinase (EC 2.7.1.82) (EK)].

CHKB_MOUSE
NC score	0.981566 (rank : 4)	θ value	2.89301e-115 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	O55229	Gene names	Chkb, Chetk, Chkl
Domain Architecture
Description	Choline/ethanolamine kinase [Includes: Choline kinase beta (EC 2.7.1.32) (CK); Ethanolamine kinase (EC 2.7.1.82) (EK)].

EKI1_HUMAN
NC score	0.836633 (rank : 5)	θ value	1.01765e-35 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HBU6	Gene names	ETNK1, EKI1
Domain Architecture
Description	Ethanolamine kinase 1 (EC 2.7.1.82) (EKI 1).

EKI2_HUMAN
NC score	0.747790 (rank : 6)	θ value	7.32683e-18 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NVF9	Gene names	ETNK2, EKI2
Domain Architecture
Description	Ethanolamine kinase 2 (EC 2.7.1.82) (EKI 2) (Ethanolamine kinase-like protein).

RBM6_HUMAN
NC score	0.042667 (rank : 7)	θ value	0.279714 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	221	Shared Neighborhood Hits	3
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

TS1R3_HUMAN
NC score	0.019315 (rank : 8)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q7RTX0, Q5TA49, Q8NGW9	Gene names	TAS1R3, T1R3, TR3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3).

ALEX_HUMAN
NC score	0.015633 (rank : 9)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	361	Shared Neighborhood Hits	6
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

RP3A_MOUSE
NC score	0.013000 (rank : 10)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	510	Shared Neighborhood Hits	10
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

PSL1_HUMAN
NC score	0.012030 (rank : 11)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	650	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

TENS4_MOUSE
NC score	0.009784 (rank : 12)	θ value	8.99809 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	225	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

SON_HUMAN
NC score	0.009198 (rank : 13)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	1568	Shared Neighborhood Hits	10
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

MTMR3_MOUSE
NC score	0.009113 (rank : 14)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	78	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K296	Gene names	Mtmr3
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48).

IF4B_MOUSE
NC score	0.008690 (rank : 15)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	368	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

PCLO_MOUSE
NC score	0.007610 (rank : 16)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	2275	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

CBP_MOUSE
NC score	0.006991 (rank : 17)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	1051	Shared Neighborhood Hits	8
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

PMYT1_MOUSE
NC score	0.006983 (rank : 18)	θ value	0.279714 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	910	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ESG9, Q8R3L4	Gene names	Pkmyt1, Myt1
Domain Architecture	No domain graphic available
Description	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase).

BAI2_HUMAN
NC score	0.005725 (rank : 19)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	332	Shared Neighborhood Hits	4
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
NC score	0.005683 (rank : 20)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	323	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

AATK_HUMAN
NC score	0.005041 (rank : 21)	θ value	1.38821 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	1243	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

RGS3_MOUSE
NC score	0.004273 (rank : 22)	θ value	8.99809 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	1621	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TLK1_MOUSE
NC score	0.002123 (rank : 23)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	947	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C0V0	Gene names	Tlk1
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1).

TLK1_HUMAN
NC score	0.002111 (rank : 24)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	967	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKI8, Q14150, Q8N591, Q9NYH2, Q9Y4F6	Gene names	TLK1, KIAA0137
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1) (PKU-beta).

ZN710_HUMAN
NC score	0.000684 (rank : 25)	θ value	2.36792 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	796	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N1W2, Q6ZMK9, Q8NDU0	Gene names	ZNF710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.