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Network neighborhood for query Sequence : BL1S3_HUMAN

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BL1S3_HUMAN
SwissProt Accessions	Q6QNY0	Gene names	BLOC1S3, BLOS3
Domain Architecture	No domain graphic available
Description	Biogenesis of lysosome-related organelles complex-1 subunit 3 (BLOC subunit 3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BL1S3_HUMAN
θ value	8.85319e-56 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q6QNY0	Gene names	BLOC1S3, BLOS3
Domain Architecture	No domain graphic available
Description	Biogenesis of lysosome-related organelles complex-1 subunit 3 (BLOC subunit 3).

BL1S3_MOUSE
θ value	1.67352e-46 (rank : 2)	NC score	0.983708 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q5U5M8, Q8C6R4, Q8R0Z3	Gene names	Bloc1s3, Blos3, Rp
Domain Architecture	No domain graphic available
Description	Biogenesis of lysosome-related organelles complex-1 subunit 3 (Reduced pigmentation protein) (BLOC subunit 3).

MAST2_HUMAN
θ value	0.125558 (rank : 3)	NC score	0.015304 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	1189	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MDC1_MOUSE
θ value	0.62314 (rank : 4)	NC score	0.044631 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	998	Shared Neighborhood Hits	7
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

GNAS1_MOUSE
θ value	1.06291 (rank : 5)	NC score	0.022641 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	651	Shared Neighborhood Hits	3
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

UB7I1_HUMAN
θ value	2.36792 (rank : 6)	NC score	0.038242 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	177	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

AMPH_MOUSE
θ value	3.0926 (rank : 7)	NC score	0.030664 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	291	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

TF65_MOUSE
θ value	3.0926 (rank : 8)	NC score	0.025110 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	66	Shared Neighborhood Hits	2
SwissProt Accessions	Q04207, Q62025	Gene names	Rela, Nfkb3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

SEN34_MOUSE
θ value	5.27518 (rank : 9)	NC score	0.031931 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

AL2S4_MOUSE
θ value	6.88961 (rank : 10)	NC score	0.025874 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	193	Shared Neighborhood Hits	2
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

FOG1_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.006211 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	1237	Shared Neighborhood Hits	4
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

SAPS1_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.016404 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	704	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

ATRX_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.010130 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	842	Shared Neighborhood Hits	2
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

GEMI5_MOUSE
θ value	8.99809 (rank : 14)	NC score	0.012744 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	424	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

NFIP2_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.024115 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NV92, Q7Z2H3, Q7Z428, Q8TAR3, Q9ULQ5	Gene names	NDFIP2, KIAA1165, N4WBP5A
Domain Architecture	No domain graphic available
Description	NEDD4 family-interacting protein 2 (NEDD4 WW domain-binding protein 5A) (Putative MAPK-activating protein PM04/PM05/PM06/PM07) (Putative NF-kappa-B-activating protein 413).

RAD9A_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.020478 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q99638, Q6FI29, Q96C41	Gene names	RAD9A
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint control protein RAD9A (EC 3.1.11.2) (DNA repair exonuclease rad9 homolog A) (hRAD9).

TOPB1_MOUSE
θ value	8.99809 (rank : 17)	NC score	0.019998 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

Hits sorted by NC score

BL1S3_HUMAN
NC score	0.999962 (rank : 1)	θ value	8.85319e-56 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q6QNY0	Gene names	BLOC1S3, BLOS3
Domain Architecture	No domain graphic available
Description	Biogenesis of lysosome-related organelles complex-1 subunit 3 (BLOC subunit 3).

BL1S3_MOUSE
NC score	0.983708 (rank : 2)	θ value	1.67352e-46 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q5U5M8, Q8C6R4, Q8R0Z3	Gene names	Bloc1s3, Blos3, Rp
Domain Architecture	No domain graphic available
Description	Biogenesis of lysosome-related organelles complex-1 subunit 3 (Reduced pigmentation protein) (BLOC subunit 3).

MDC1_MOUSE
NC score	0.044631 (rank : 3)	θ value	0.62314 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	998	Shared Neighborhood Hits	7
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

UB7I1_HUMAN
NC score	0.038242 (rank : 4)	θ value	2.36792 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	177	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

SEN34_MOUSE
NC score	0.031931 (rank : 5)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

AMPH_MOUSE
NC score	0.030664 (rank : 6)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	291	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

AL2S4_MOUSE
NC score	0.025874 (rank : 7)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	193	Shared Neighborhood Hits	2
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

TF65_MOUSE
NC score	0.025110 (rank : 8)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	66	Shared Neighborhood Hits	2
SwissProt Accessions	Q04207, Q62025	Gene names	Rela, Nfkb3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

NFIP2_HUMAN
NC score	0.024115 (rank : 9)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NV92, Q7Z2H3, Q7Z428, Q8TAR3, Q9ULQ5	Gene names	NDFIP2, KIAA1165, N4WBP5A
Domain Architecture	No domain graphic available
Description	NEDD4 family-interacting protein 2 (NEDD4 WW domain-binding protein 5A) (Putative MAPK-activating protein PM04/PM05/PM06/PM07) (Putative NF-kappa-B-activating protein 413).

GNAS1_MOUSE
NC score	0.022641 (rank : 10)	θ value	1.06291 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	651	Shared Neighborhood Hits	3
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

RAD9A_HUMAN
NC score	0.020478 (rank : 11)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q99638, Q6FI29, Q96C41	Gene names	RAD9A
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint control protein RAD9A (EC 3.1.11.2) (DNA repair exonuclease rad9 homolog A) (hRAD9).

TOPB1_MOUSE
NC score	0.019998 (rank : 12)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

SAPS1_HUMAN
NC score	0.016404 (rank : 13)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	704	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

MAST2_HUMAN
NC score	0.015304 (rank : 14)	θ value	0.125558 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	1189	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

GEMI5_MOUSE
NC score	0.012744 (rank : 15)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	424	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

ATRX_HUMAN
NC score	0.010130 (rank : 16)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	842	Shared Neighborhood Hits	2
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

FOG1_MOUSE
NC score	0.006211 (rank : 17)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	1237	Shared Neighborhood Hits	4
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).