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Network neighborhood for query Sequence : ARSA_MOUSE

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ARSA_MOUSE
SwissProt Accessions	P50428	Gene names	Arsa, As2
Domain Architecture
Description	Arylsulfatase A precursor (EC 3.1.6.8) (ASA) (Cerebroside-sulfatase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ARSA_HUMAN
θ value	0 (rank : 1)	NC score	0.994567 (rank : 2)
Query Neighborhood Hits	30	Target Neighborhood Hits	26	Shared Neighborhood Hits	25
SwissProt Accessions	P15289, Q6ICI5, Q96CJ0	Gene names	ARSA
Domain Architecture
Description	Arylsulfatase A precursor (EC 3.1.6.8) (ASA) (Cerebroside-sulfatase) [Contains: Arylsulfatase A component B; Arylsulfatase A component C].

ARSA_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	30
SwissProt Accessions	P50428	Gene names	Arsa, As2
Domain Architecture
Description	Arylsulfatase A precursor (EC 3.1.6.8) (ASA) (Cerebroside-sulfatase).

ARSG_HUMAN
θ value	1.27248e-70 (rank : 3)	NC score	0.941864 (rank : 5)
Query Neighborhood Hits	30	Target Neighborhood Hits	32	Shared Neighborhood Hits	23
SwissProt Accessions	Q96EG1, Q6UXF2, Q9Y2K4	Gene names	ARSG, KIAA1001
Domain Architecture	No domain graphic available
Description	Arylsulfatase G precursor (EC 3.1.6.-) (ASG).

ARSG_MOUSE
θ value	4.52582e-68 (rank : 4)	NC score	0.946441 (rank : 4)
Query Neighborhood Hits	30	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q3TYD4, Q5XFU5, Q69ZT6, Q8CHS3, Q8VBZ5, Q9D3B4	Gene names	Arsg, Kiaa1001
Domain Architecture	No domain graphic available
Description	Arylsulfatase G precursor (EC 3.1.6.-) (ASG).

GA6S_HUMAN
θ value	1.50663e-63 (rank : 5)	NC score	0.955743 (rank : 3)
Query Neighborhood Hits	30	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	P34059, Q86VK3	Gene names	GALNS
Domain Architecture
Description	N-acetylgalactosamine-6-sulfatase precursor (EC 3.1.6.4) (N- acetylgalactosamine-6-sulfate sulfatase) (Galactose-6-sulfate sulfatase) (GalNAc6S sulfatase) (Chondroitinsulfatase) (Chondroitinase).

STS_MOUSE
θ value	1.788e-48 (rank : 6)	NC score	0.894491 (rank : 6)
Query Neighborhood Hits	30	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	P50427	Gene names	Sts
Domain Architecture
Description	Steryl-sulfatase precursor (EC 3.1.6.2) (Steroid sulfatase) (Steryl- sulfate sulfohydrolase) (Arylsulfatase C) (ASC).

ARSD_HUMAN
θ value	3.26607e-42 (rank : 7)	NC score	0.867426 (rank : 7)
Query Neighborhood Hits	30	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	P51689, Q9UHJ8	Gene names	ARSD
Domain Architecture
Description	Arylsulfatase D precursor (EC 3.1.6.-) (ASD).

ARSE_HUMAN
θ value	8.32485e-38 (rank : 8)	NC score	0.862286 (rank : 9)
Query Neighborhood Hits	30	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	P51690, Q53FT2, Q53FU8	Gene names	ARSE
Domain Architecture
Description	Arylsulfatase E precursor (EC 3.1.6.-) (ASE).

ARSI_HUMAN
θ value	2.34606e-32 (rank : 9)	NC score	0.837822 (rank : 11)
Query Neighborhood Hits	30	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	Q5FYB1	Gene names	ARSI
Domain Architecture	No domain graphic available
Description	Arylsulfatase I precursor (EC 3.1.6.-) (ASI).

STS_HUMAN
θ value	1.16434e-31 (rank : 10)	NC score	0.860926 (rank : 10)
Query Neighborhood Hits	30	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	P08842	Gene names	STS
Domain Architecture
Description	Steryl-sulfatase precursor (EC 3.1.6.2) (Steroid sulfatase) (Steryl- sulfate sulfohydrolase) (Arylsulfatase C) (ASC).

ARSJ_HUMAN
θ value	2.42779e-29 (rank : 11)	NC score	0.824449 (rank : 13)
Query Neighborhood Hits	30	Target Neighborhood Hits	27	Shared Neighborhood Hits	23
SwissProt Accessions	Q5FYB0, Q5FWE4, Q6UWT9	Gene names	ARSJ
Domain Architecture	No domain graphic available
Description	Arylsulfatase J precursor (EC 3.1.6.-) (ASJ).

ARSJ_MOUSE
θ value	2.42779e-29 (rank : 12)	NC score	0.822217 (rank : 14)
Query Neighborhood Hits	30	Target Neighborhood Hits	32	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BM89, Q8BKG5, Q8BL46	Gene names	Arsj
Domain Architecture	No domain graphic available
Description	Arylsulfatase J precursor (EC 3.1.6.-) (ASJ).

ARSF_HUMAN
θ value	4.28545e-26 (rank : 13)	NC score	0.865975 (rank : 8)
Query Neighborhood Hits	30	Target Neighborhood Hits	33	Shared Neighborhood Hits	25
SwissProt Accessions	P54793, Q8TCC5	Gene names	ARSF
Domain Architecture
Description	Arylsulfatase F precursor (EC 3.1.6.-) (ASF).

ARSB_HUMAN
θ value	6.18819e-25 (rank : 14)	NC score	0.836350 (rank : 12)
Query Neighborhood Hits	30	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	P15848	Gene names	ARSB
Domain Architecture
Description	Arylsulfatase B precursor (EC 3.1.6.12) (ASB) (N-acetylgalactosamine- 4-sulfatase) (G4S).

SPHM_HUMAN
θ value	1.68911e-14 (rank : 15)	NC score	0.764792 (rank : 15)
Query Neighborhood Hits	30	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	P51688	Gene names	SGSH, HSS
Domain Architecture
Description	N-sulphoglucosamine sulphohydrolase precursor (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase).

IDS_MOUSE
θ value	4.91457e-14 (rank : 16)	NC score	0.705669 (rank : 16)
Query Neighborhood Hits	30	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	Q08890, Q3TM30	Gene names	Ids
Domain Architecture
Description	Iduronate 2-sulfatase precursor (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase).

SULF1_MOUSE
θ value	2.43908e-13 (rank : 17)	NC score	0.543593 (rank : 20)
Query Neighborhood Hits	30	Target Neighborhood Hits	52	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K007, Q8BLJ0, Q8C1D3	Gene names	Sulf1
Domain Architecture
Description	Extracellular sulfatase Sulf-1 precursor (EC 3.1.6.-) (MSulf-1).

SULF1_HUMAN
θ value	3.52202e-12 (rank : 18)	NC score	0.536291 (rank : 22)
Query Neighborhood Hits	30	Target Neighborhood Hits	55	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IWU6, Q86YV8, Q8NCA2, Q9UPS5	Gene names	SULF1, KIAA1077
Domain Architecture
Description	Extracellular sulfatase Sulf-1 precursor (EC 3.1.6.-) (HSulf-1).

IDS_HUMAN
θ value	1.02475e-11 (rank : 19)	NC score	0.698031 (rank : 17)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P22304, Q14604	Gene names	IDS
Domain Architecture
Description	Iduronate 2-sulfatase precursor (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Contains: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain].

SULF2_MOUSE
θ value	1.02475e-11 (rank : 20)	NC score	0.540564 (rank : 21)
Query Neighborhood Hits	30	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CFG0, Q8BM68, Q8BUZ4, Q8BX28, Q8BZ51, Q8C169, Q9D8E2	Gene names	Sulf2
Domain Architecture
Description	Extracellular sulfatase Sulf-2 precursor (EC 3.1.6.-) (MSulf-2).

SULF2_HUMAN
θ value	1.74796e-11 (rank : 21)	NC score	0.532558 (rank : 23)
Query Neighborhood Hits	30	Target Neighborhood Hits	31	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IWU5, Q6UX86, Q96SG2, Q9H1H0, Q9UJR3, Q9ULH3	Gene names	SULF2, KIAA1247
Domain Architecture
Description	Extracellular sulfatase Sulf-2 precursor (EC 3.1.6.-) (HSulf-2).

GL6S_HUMAN
θ value	2.52405e-10 (rank : 22)	NC score	0.615421 (rank : 19)
Query Neighborhood Hits	30	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	P15586	Gene names	GNS
Domain Architecture
Description	N-acetylglucosamine-6-sulfatase precursor (EC 3.1.6.14) (G6S) (Glucosamine-6-sulfatase).

ARSK_HUMAN
θ value	1.06045e-08 (rank : 23)	NC score	0.624356 (rank : 18)
Query Neighborhood Hits	30	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	Q6UWY0, Q8N3Q8	Gene names	ARSK, TSULF
Domain Architecture	No domain graphic available
Description	Arylsulfatase K precursor (EC 3.1.6.-) (ASK) (Telethon sulfatase).

ENPP2_MOUSE
θ value	0.62314 (rank : 24)	NC score	0.040396 (rank : 25)
Query Neighborhood Hits	30	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

CCD1A_HUMAN
θ value	0.813845 (rank : 25)	NC score	0.024984 (rank : 27)
Query Neighborhood Hits	30	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P1N0, Q7Z435, Q86XV0, Q8NF89, Q9H603, Q9NXI1	Gene names	CC2D1A
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B- activating protein 023N).

ENPP2_HUMAN
θ value	0.813845 (rank : 26)	NC score	0.039403 (rank : 26)
Query Neighborhood Hits	30	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

TSG6_MOUSE
θ value	2.36792 (rank : 27)	NC score	0.011008 (rank : 28)
Query Neighborhood Hits	30	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

CO4A1_MOUSE
θ value	5.27518 (rank : 28)	NC score	0.002040 (rank : 31)
Query Neighborhood Hits	30	Target Neighborhood Hits	450	Shared Neighborhood Hits	2
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

IRF3_MOUSE
θ value	6.88961 (rank : 29)	NC score	0.007236 (rank : 30)
Query Neighborhood Hits	30	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	P70671	Gene names	Irf3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

TSG6_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.008770 (rank : 29)
Query Neighborhood Hits	30	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

ENPP7_HUMAN
θ value	θ > 10 (rank : 31)	NC score	0.052060 (rank : 24)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q6UWV6, Q6ZTS5, Q8IUS8	Gene names	ENPP7
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 7 precursor (EC 3.1.4.12) (E-NPP7) (NPP-7) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase).

Hits sorted by NC score

ARSA_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	30
SwissProt Accessions	P50428	Gene names	Arsa, As2
Domain Architecture
Description	Arylsulfatase A precursor (EC 3.1.6.8) (ASA) (Cerebroside-sulfatase).

ARSA_HUMAN
NC score	0.994567 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	30	Target Neighborhood Hits	26	Shared Neighborhood Hits	25
SwissProt Accessions	P15289, Q6ICI5, Q96CJ0	Gene names	ARSA
Domain Architecture
Description	Arylsulfatase A precursor (EC 3.1.6.8) (ASA) (Cerebroside-sulfatase) [Contains: Arylsulfatase A component B; Arylsulfatase A component C].

GA6S_HUMAN
NC score	0.955743 (rank : 3)	θ value	1.50663e-63 (rank : 5)
Query Neighborhood Hits	30	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	P34059, Q86VK3	Gene names	GALNS
Domain Architecture
Description	N-acetylgalactosamine-6-sulfatase precursor (EC 3.1.6.4) (N- acetylgalactosamine-6-sulfate sulfatase) (Galactose-6-sulfate sulfatase) (GalNAc6S sulfatase) (Chondroitinsulfatase) (Chondroitinase).

ARSG_MOUSE
NC score	0.946441 (rank : 4)	θ value	4.52582e-68 (rank : 4)
Query Neighborhood Hits	30	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q3TYD4, Q5XFU5, Q69ZT6, Q8CHS3, Q8VBZ5, Q9D3B4	Gene names	Arsg, Kiaa1001
Domain Architecture	No domain graphic available
Description	Arylsulfatase G precursor (EC 3.1.6.-) (ASG).

ARSG_HUMAN
NC score	0.941864 (rank : 5)	θ value	1.27248e-70 (rank : 3)
Query Neighborhood Hits	30	Target Neighborhood Hits	32	Shared Neighborhood Hits	23
SwissProt Accessions	Q96EG1, Q6UXF2, Q9Y2K4	Gene names	ARSG, KIAA1001
Domain Architecture	No domain graphic available
Description	Arylsulfatase G precursor (EC 3.1.6.-) (ASG).

STS_MOUSE
NC score	0.894491 (rank : 6)	θ value	1.788e-48 (rank : 6)
Query Neighborhood Hits	30	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	P50427	Gene names	Sts
Domain Architecture
Description	Steryl-sulfatase precursor (EC 3.1.6.2) (Steroid sulfatase) (Steryl- sulfate sulfohydrolase) (Arylsulfatase C) (ASC).

ARSD_HUMAN
NC score	0.867426 (rank : 7)	θ value	3.26607e-42 (rank : 7)
Query Neighborhood Hits	30	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	P51689, Q9UHJ8	Gene names	ARSD
Domain Architecture
Description	Arylsulfatase D precursor (EC 3.1.6.-) (ASD).

ARSF_HUMAN
NC score	0.865975 (rank : 8)	θ value	4.28545e-26 (rank : 13)
Query Neighborhood Hits	30	Target Neighborhood Hits	33	Shared Neighborhood Hits	25
SwissProt Accessions	P54793, Q8TCC5	Gene names	ARSF
Domain Architecture
Description	Arylsulfatase F precursor (EC 3.1.6.-) (ASF).

ARSE_HUMAN
NC score	0.862286 (rank : 9)	θ value	8.32485e-38 (rank : 8)
Query Neighborhood Hits	30	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	P51690, Q53FT2, Q53FU8	Gene names	ARSE
Domain Architecture
Description	Arylsulfatase E precursor (EC 3.1.6.-) (ASE).

STS_HUMAN
NC score	0.860926 (rank : 10)	θ value	1.16434e-31 (rank : 10)
Query Neighborhood Hits	30	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	P08842	Gene names	STS
Domain Architecture
Description	Steryl-sulfatase precursor (EC 3.1.6.2) (Steroid sulfatase) (Steryl- sulfate sulfohydrolase) (Arylsulfatase C) (ASC).

ARSI_HUMAN
NC score	0.837822 (rank : 11)	θ value	2.34606e-32 (rank : 9)
Query Neighborhood Hits	30	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	Q5FYB1	Gene names	ARSI
Domain Architecture	No domain graphic available
Description	Arylsulfatase I precursor (EC 3.1.6.-) (ASI).

ARSB_HUMAN
NC score	0.836350 (rank : 12)	θ value	6.18819e-25 (rank : 14)
Query Neighborhood Hits	30	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	P15848	Gene names	ARSB
Domain Architecture
Description	Arylsulfatase B precursor (EC 3.1.6.12) (ASB) (N-acetylgalactosamine- 4-sulfatase) (G4S).

ARSJ_HUMAN
NC score	0.824449 (rank : 13)	θ value	2.42779e-29 (rank : 11)
Query Neighborhood Hits	30	Target Neighborhood Hits	27	Shared Neighborhood Hits	23
SwissProt Accessions	Q5FYB0, Q5FWE4, Q6UWT9	Gene names	ARSJ
Domain Architecture	No domain graphic available
Description	Arylsulfatase J precursor (EC 3.1.6.-) (ASJ).

ARSJ_MOUSE
NC score	0.822217 (rank : 14)	θ value	2.42779e-29 (rank : 12)
Query Neighborhood Hits	30	Target Neighborhood Hits	32	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BM89, Q8BKG5, Q8BL46	Gene names	Arsj
Domain Architecture	No domain graphic available
Description	Arylsulfatase J precursor (EC 3.1.6.-) (ASJ).

SPHM_HUMAN
NC score	0.764792 (rank : 15)	θ value	1.68911e-14 (rank : 15)
Query Neighborhood Hits	30	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	P51688	Gene names	SGSH, HSS
Domain Architecture
Description	N-sulphoglucosamine sulphohydrolase precursor (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase).

IDS_MOUSE
NC score	0.705669 (rank : 16)	θ value	4.91457e-14 (rank : 16)
Query Neighborhood Hits	30	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	Q08890, Q3TM30	Gene names	Ids
Domain Architecture
Description	Iduronate 2-sulfatase precursor (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase).

IDS_HUMAN
NC score	0.698031 (rank : 17)	θ value	1.02475e-11 (rank : 19)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P22304, Q14604	Gene names	IDS
Domain Architecture
Description	Iduronate 2-sulfatase precursor (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Contains: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain].

ARSK_HUMAN
NC score	0.624356 (rank : 18)	θ value	1.06045e-08 (rank : 23)
Query Neighborhood Hits	30	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	Q6UWY0, Q8N3Q8	Gene names	ARSK, TSULF
Domain Architecture	No domain graphic available
Description	Arylsulfatase K precursor (EC 3.1.6.-) (ASK) (Telethon sulfatase).

GL6S_HUMAN
NC score	0.615421 (rank : 19)	θ value	2.52405e-10 (rank : 22)
Query Neighborhood Hits	30	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	P15586	Gene names	GNS
Domain Architecture
Description	N-acetylglucosamine-6-sulfatase precursor (EC 3.1.6.14) (G6S) (Glucosamine-6-sulfatase).

SULF1_MOUSE
NC score	0.543593 (rank : 20)	θ value	2.43908e-13 (rank : 17)
Query Neighborhood Hits	30	Target Neighborhood Hits	52	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K007, Q8BLJ0, Q8C1D3	Gene names	Sulf1
Domain Architecture
Description	Extracellular sulfatase Sulf-1 precursor (EC 3.1.6.-) (MSulf-1).

SULF2_MOUSE
NC score	0.540564 (rank : 21)	θ value	1.02475e-11 (rank : 20)
Query Neighborhood Hits	30	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CFG0, Q8BM68, Q8BUZ4, Q8BX28, Q8BZ51, Q8C169, Q9D8E2	Gene names	Sulf2
Domain Architecture
Description	Extracellular sulfatase Sulf-2 precursor (EC 3.1.6.-) (MSulf-2).

SULF1_HUMAN
NC score	0.536291 (rank : 22)	θ value	3.52202e-12 (rank : 18)
Query Neighborhood Hits	30	Target Neighborhood Hits	55	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IWU6, Q86YV8, Q8NCA2, Q9UPS5	Gene names	SULF1, KIAA1077
Domain Architecture
Description	Extracellular sulfatase Sulf-1 precursor (EC 3.1.6.-) (HSulf-1).

SULF2_HUMAN
NC score	0.532558 (rank : 23)	θ value	1.74796e-11 (rank : 21)
Query Neighborhood Hits	30	Target Neighborhood Hits	31	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IWU5, Q6UX86, Q96SG2, Q9H1H0, Q9UJR3, Q9ULH3	Gene names	SULF2, KIAA1247
Domain Architecture
Description	Extracellular sulfatase Sulf-2 precursor (EC 3.1.6.-) (HSulf-2).

ENPP7_HUMAN
NC score	0.052060 (rank : 24)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q6UWV6, Q6ZTS5, Q8IUS8	Gene names	ENPP7
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 7 precursor (EC 3.1.4.12) (E-NPP7) (NPP-7) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase).

ENPP2_MOUSE
NC score	0.040396 (rank : 25)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	30	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP2_HUMAN
NC score	0.039403 (rank : 26)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	30	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

CCD1A_HUMAN
NC score	0.024984 (rank : 27)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	30	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P1N0, Q7Z435, Q86XV0, Q8NF89, Q9H603, Q9NXI1	Gene names	CC2D1A
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B- activating protein 023N).

TSG6_MOUSE
NC score	0.011008 (rank : 28)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	30	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TSG6_HUMAN
NC score	0.008770 (rank : 29)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	30	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

IRF3_MOUSE
NC score	0.007236 (rank : 30)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	30	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	P70671	Gene names	Irf3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

CO4A1_MOUSE
NC score	0.002040 (rank : 31)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	30	Target Neighborhood Hits	450	Shared Neighborhood Hits	2
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.