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Network neighborhood for query Sequence : TF2H1_MOUSE

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TF2H1_MOUSE
SwissProt Accessions	Q9DBA9, O35637	Gene names	Gtf2h1
Domain Architecture
Description	TFIIH basal transcription factor complex p62 subunit (Basic transcription factor 62 kDa subunit) (BTF2-p62) (General transcription factor IIH polypeptide 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TF2H1_HUMAN
θ value	0 (rank : 1)	NC score	0.997211 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	17	Shared Neighborhood Hits	13
SwissProt Accessions	P32780, Q9H5K5, Q9NQD9	Gene names	GTF2H1, BTF2
Domain Architecture
Description	TFIIH basal transcription factor complex p62 subunit (Basic transcription factor 62 kDa subunit) (BTF2-p62) (General transcription factor IIH polypeptide 1).

TF2H1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q9DBA9, O35637	Gene names	Gtf2h1
Domain Architecture
Description	TFIIH basal transcription factor complex p62 subunit (Basic transcription factor 62 kDa subunit) (BTF2-p62) (General transcription factor IIH polypeptide 1).

TAC2N_MOUSE
θ value	0.47712 (rank : 3)	NC score	0.078152 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q91XT6, Q9D4A0	Gene names	Mtac2d1
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

TAC2N_HUMAN
θ value	1.06291 (rank : 4)	NC score	0.056536 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N9U0	Gene names	MTAC2D1, C14orf47
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

SDK1_MOUSE
θ value	1.38821 (rank : 5)	NC score	0.009930 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	495	Shared Neighborhood Hits	2
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SEP10_HUMAN
θ value	1.81305 (rank : 6)	NC score	0.025839 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	161	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P0V9, Q9HAH6	Gene names	SEPT10
Domain Architecture	No domain graphic available
Description	Septin-10.

SYNE2_HUMAN
θ value	2.36792 (rank : 7)	NC score	0.020910 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	1323	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

HHEX_HUMAN
θ value	4.03905 (rank : 8)	NC score	0.017940 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	358	Shared Neighborhood Hits	4
SwissProt Accessions	Q03014	Gene names	HHEX, HEX, PRH, PRHX
Domain Architecture
Description	Homeobox protein PRH (Hematopoietically expressed homeobox) (Homeobox protein HEX).

HHEX_MOUSE
θ value	4.03905 (rank : 9)	NC score	0.018007 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	350	Shared Neighborhood Hits	4
SwissProt Accessions	P43120	Gene names	Hhex, Prhx
Domain Architecture
Description	Homeobox protein PRH (Hematopoietically expressed homeobox) (Homeobox protein HEX).

LCOR_MOUSE
θ value	4.03905 (rank : 10)	NC score	0.027117 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZPI3, Q3U302, Q5CZW7, Q80VA8, Q8BGT2, Q8C9Q0	Gene names	Lcor, Kiaa1795, Mlr2
Domain Architecture	No domain graphic available
Description	Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2).

CARD6_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.068489 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	145	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BX69	Gene names	CARD6
Domain Architecture
Description	Caspase recruitment domain-containing protein 6.

RBBP6_MOUSE
θ value	5.27518 (rank : 12)	NC score	0.012375 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	1014	Shared Neighborhood Hits	4
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

TPR_HUMAN
θ value	5.27518 (rank : 13)	NC score	0.010397 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	1921	Shared Neighborhood Hits	9
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

CENPE_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.007385 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	2060	Shared Neighborhood Hits	8
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

EVPL_HUMAN
θ value	6.88961 (rank : 15)	NC score	0.013004 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	895	Shared Neighborhood Hits	7
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

SEP10_MOUSE
θ value	6.88961 (rank : 16)	NC score	0.018430 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	145	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C650, Q7TSA5	Gene names	Sept10
Domain Architecture	No domain graphic available
Description	Septin-10.

SYNE1_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.012321 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	1484	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TNF11_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.018276 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	O14788, O14723, Q96Q17, Q9P2Q3	Gene names	TNFSF11, OPGL, RANKL, TRANCE
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 11 (Receptor activator of nuclear factor kappa B ligand) (RANKL) (TNF-related activation- induced cytokine) (TRANCE) (Osteoprotegerin ligand) (OPGL) (Osteoclast differentiation factor) (ODF) (CD254 antigen) [Contains: Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form].

USBP1_MOUSE
θ value	6.88961 (rank : 19)	NC score	0.026858 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	115	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R370	Gene names	Ushbp1
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1).

Hits sorted by NC score

TF2H1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q9DBA9, O35637	Gene names	Gtf2h1
Domain Architecture
Description	TFIIH basal transcription factor complex p62 subunit (Basic transcription factor 62 kDa subunit) (BTF2-p62) (General transcription factor IIH polypeptide 1).

TF2H1_HUMAN
NC score	0.997211 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	17	Shared Neighborhood Hits	13
SwissProt Accessions	P32780, Q9H5K5, Q9NQD9	Gene names	GTF2H1, BTF2
Domain Architecture
Description	TFIIH basal transcription factor complex p62 subunit (Basic transcription factor 62 kDa subunit) (BTF2-p62) (General transcription factor IIH polypeptide 1).

TAC2N_MOUSE
NC score	0.078152 (rank : 3)	θ value	0.47712 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q91XT6, Q9D4A0	Gene names	Mtac2d1
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

CARD6_HUMAN
NC score	0.068489 (rank : 4)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	145	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BX69	Gene names	CARD6
Domain Architecture
Description	Caspase recruitment domain-containing protein 6.

TAC2N_HUMAN
NC score	0.056536 (rank : 5)	θ value	1.06291 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N9U0	Gene names	MTAC2D1, C14orf47
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

LCOR_MOUSE
NC score	0.027117 (rank : 6)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZPI3, Q3U302, Q5CZW7, Q80VA8, Q8BGT2, Q8C9Q0	Gene names	Lcor, Kiaa1795, Mlr2
Domain Architecture	No domain graphic available
Description	Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2).

USBP1_MOUSE
NC score	0.026858 (rank : 7)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	115	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R370	Gene names	Ushbp1
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1).

SEP10_HUMAN
NC score	0.025839 (rank : 8)	θ value	1.81305 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	161	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P0V9, Q9HAH6	Gene names	SEPT10
Domain Architecture	No domain graphic available
Description	Septin-10.

SYNE2_HUMAN
NC score	0.020910 (rank : 9)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	1323	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

SEP10_MOUSE
NC score	0.018430 (rank : 10)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	145	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C650, Q7TSA5	Gene names	Sept10
Domain Architecture	No domain graphic available
Description	Septin-10.

TNF11_HUMAN
NC score	0.018276 (rank : 11)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	O14788, O14723, Q96Q17, Q9P2Q3	Gene names	TNFSF11, OPGL, RANKL, TRANCE
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 11 (Receptor activator of nuclear factor kappa B ligand) (RANKL) (TNF-related activation- induced cytokine) (TRANCE) (Osteoprotegerin ligand) (OPGL) (Osteoclast differentiation factor) (ODF) (CD254 antigen) [Contains: Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form].

HHEX_MOUSE
NC score	0.018007 (rank : 12)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	350	Shared Neighborhood Hits	4
SwissProt Accessions	P43120	Gene names	Hhex, Prhx
Domain Architecture
Description	Homeobox protein PRH (Hematopoietically expressed homeobox) (Homeobox protein HEX).

HHEX_HUMAN
NC score	0.017940 (rank : 13)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	358	Shared Neighborhood Hits	4
SwissProt Accessions	Q03014	Gene names	HHEX, HEX, PRH, PRHX
Domain Architecture
Description	Homeobox protein PRH (Hematopoietically expressed homeobox) (Homeobox protein HEX).

EVPL_HUMAN
NC score	0.013004 (rank : 14)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	895	Shared Neighborhood Hits	7
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

RBBP6_MOUSE
NC score	0.012375 (rank : 15)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	1014	Shared Neighborhood Hits	4
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

SYNE1_HUMAN
NC score	0.012321 (rank : 16)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	1484	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TPR_HUMAN
NC score	0.010397 (rank : 17)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	1921	Shared Neighborhood Hits	9
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

SDK1_MOUSE
NC score	0.009930 (rank : 18)	θ value	1.38821 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	495	Shared Neighborhood Hits	2
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

CENPE_HUMAN
NC score	0.007385 (rank : 19)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	2060	Shared Neighborhood Hits	8
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).