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Network neighborhood for query Sequence : SRTD2_MOUSE

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SRTD2_MOUSE
SwissProt Accessions	Q9JJG5, Q8C609, Q91WL3, Q925E5	Gene names	Sertad2, Kiaa0127
Domain Architecture
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SRTD2_MOUSE
θ value	6.60789e-144 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JJG5, Q8C609, Q91WL3, Q925E5	Gene names	Sertad2, Kiaa0127
Domain Architecture
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

SRTD2_HUMAN
θ value	3.29472e-127 (rank : 2)	NC score	0.962784 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	Q14140	Gene names	SERTAD2, KIAA0127
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

CDCA4_HUMAN
θ value	2.35696e-16 (rank : 3)	NC score	0.657468 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BXL8, Q8TB18, Q9NWK7	Gene names	CDCA4, HEPP
Domain Architecture
Description	Cell division cycle-associated protein 4 (Hematopoietic progenitor protein).

CDCA4_MOUSE
θ value	5.25075e-16 (rank : 4)	NC score	0.660876 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CWM2, Q3U1C0, Q921E8, Q99MP6	Gene names	Cdca4, Hepp
Domain Architecture
Description	Cell division cycle-associated protein 4 (Hematopoietic progenitor protein).

SRTD1_MOUSE
θ value	3.19293e-05 (rank : 5)	NC score	0.441711 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	20	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JL10, Q925E6, Q9D888	Gene names	Sertad1, Sei1
Domain Architecture
Description	SERTA domain-containing protein 1 (Transcriptional regulator interacting with the PHD-bromodomain 1) (TRIP-Br1) (CDK4-binding protein p34SEI1) (SEI-1).

SRTD1_HUMAN
θ value	5.44631e-05 (rank : 6)	NC score	0.454048 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UHV2, Q9BUE7	Gene names	SERTAD1, SEI1
Domain Architecture
Description	SERTA domain-containing protein 1 (Transcriptional regulator interacting with the PHD-bromodomain 1) (TRIP-Br1) (CDK4-binding protein p34SEI1) (SEI-1).

OGFR_HUMAN
θ value	0.0736092 (rank : 7)	NC score	0.030010 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	1582	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

DAB2_HUMAN
θ value	1.06291 (rank : 8)	NC score	0.036004 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

ARI1B_HUMAN
θ value	4.03905 (rank : 9)	NC score	0.021435 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	567	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

IP3KC_MOUSE
θ value	4.03905 (rank : 10)	NC score	0.028578 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TS72, Q3U384	Gene names	Itpkc
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (IP3K-C).

KIF17_MOUSE
θ value	4.03905 (rank : 11)	NC score	0.007904 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	452	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

PCTK1_MOUSE
θ value	4.03905 (rank : 12)	NC score	0.004681 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	832	Shared Neighborhood Hits	4
SwissProt Accessions	Q04735	Gene names	Pctk1, Crk5
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 1) (CRK5).

SRTD3_HUMAN
θ value	4.03905 (rank : 13)	NC score	0.112707 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UJW9, Q96CQ2	Gene names	SERTAD3, RBT1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).

UBP6_HUMAN
θ value	5.27518 (rank : 14)	NC score	0.010895 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

IP3KC_HUMAN
θ value	6.88961 (rank : 15)	NC score	0.025793 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q96DU7, Q9UE25, Q9Y475	Gene names	ITPKC, IP3KC
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (InsP 3-kinase C) (IP3K-C).

PCTK1_HUMAN
θ value	6.88961 (rank : 16)	NC score	0.003031 (rank : 22)
Query Neighborhood Hits	21	Target Neighborhood Hits	832	Shared Neighborhood Hits	3
SwissProt Accessions	Q00536	Gene names	PCTK1
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 1).

PSN2_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.015741 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P49810, Q96P32	Gene names	PSEN2, AD4, PS2, PSNL2, STM2
Domain Architecture
Description	Presenilin-2 (EC 3.4.23.-) (PS-2) (STM-2) (E5-1) (AD3LP) (AD5) [Contains: Presenilin-2 NTF subunit; Presenilin-2 CTF subunit].

EVPL_MOUSE
θ value	8.99809 (rank : 18)	NC score	0.004566 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	952	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

RGS3_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.006963 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	1621	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SELPL_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.015359 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	588	Shared Neighborhood Hits	4
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

TLR7_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.006626 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	312	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYK1, Q9NR98	Gene names	TLR7
Domain Architecture
Description	Toll-like receptor 7 precursor.

SRTD3_MOUSE
θ value	θ > 10 (rank : 22)	NC score	0.073562 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ERC3	Gene names	Sertad3, Rbt1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).

Hits sorted by NC score

SRTD2_MOUSE
NC score	0.999962 (rank : 1)	θ value	6.60789e-144 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JJG5, Q8C609, Q91WL3, Q925E5	Gene names	Sertad2, Kiaa0127
Domain Architecture
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

SRTD2_HUMAN
NC score	0.962784 (rank : 2)	θ value	3.29472e-127 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	Q14140	Gene names	SERTAD2, KIAA0127
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

CDCA4_MOUSE
NC score	0.660876 (rank : 3)	θ value	5.25075e-16 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CWM2, Q3U1C0, Q921E8, Q99MP6	Gene names	Cdca4, Hepp
Domain Architecture
Description	Cell division cycle-associated protein 4 (Hematopoietic progenitor protein).

CDCA4_HUMAN
NC score	0.657468 (rank : 4)	θ value	2.35696e-16 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BXL8, Q8TB18, Q9NWK7	Gene names	CDCA4, HEPP
Domain Architecture
Description	Cell division cycle-associated protein 4 (Hematopoietic progenitor protein).

SRTD1_HUMAN
NC score	0.454048 (rank : 5)	θ value	5.44631e-05 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UHV2, Q9BUE7	Gene names	SERTAD1, SEI1
Domain Architecture
Description	SERTA domain-containing protein 1 (Transcriptional regulator interacting with the PHD-bromodomain 1) (TRIP-Br1) (CDK4-binding protein p34SEI1) (SEI-1).

SRTD1_MOUSE
NC score	0.441711 (rank : 6)	θ value	3.19293e-05 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	20	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JL10, Q925E6, Q9D888	Gene names	Sertad1, Sei1
Domain Architecture
Description	SERTA domain-containing protein 1 (Transcriptional regulator interacting with the PHD-bromodomain 1) (TRIP-Br1) (CDK4-binding protein p34SEI1) (SEI-1).

SRTD3_HUMAN
NC score	0.112707 (rank : 7)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UJW9, Q96CQ2	Gene names	SERTAD3, RBT1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).

SRTD3_MOUSE
NC score	0.073562 (rank : 8)	θ value	θ > 10 (rank : 22)
Query Neighborhood Hits	21	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ERC3	Gene names	Sertad3, Rbt1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).

DAB2_HUMAN
NC score	0.036004 (rank : 9)	θ value	1.06291 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

OGFR_HUMAN
NC score	0.030010 (rank : 10)	θ value	0.0736092 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	1582	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

IP3KC_MOUSE
NC score	0.028578 (rank : 11)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TS72, Q3U384	Gene names	Itpkc
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (IP3K-C).

IP3KC_HUMAN
NC score	0.025793 (rank : 12)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q96DU7, Q9UE25, Q9Y475	Gene names	ITPKC, IP3KC
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (InsP 3-kinase C) (IP3K-C).

ARI1B_HUMAN
NC score	0.021435 (rank : 13)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	567	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

PSN2_HUMAN
NC score	0.015741 (rank : 14)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P49810, Q96P32	Gene names	PSEN2, AD4, PS2, PSNL2, STM2
Domain Architecture
Description	Presenilin-2 (EC 3.4.23.-) (PS-2) (STM-2) (E5-1) (AD3LP) (AD5) [Contains: Presenilin-2 NTF subunit; Presenilin-2 CTF subunit].

SELPL_MOUSE
NC score	0.015359 (rank : 15)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	588	Shared Neighborhood Hits	4
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

UBP6_HUMAN
NC score	0.010895 (rank : 16)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

KIF17_MOUSE
NC score	0.007904 (rank : 17)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	452	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

RGS3_MOUSE
NC score	0.006963 (rank : 18)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	1621	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TLR7_HUMAN
NC score	0.006626 (rank : 19)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	312	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYK1, Q9NR98	Gene names	TLR7
Domain Architecture
Description	Toll-like receptor 7 precursor.

PCTK1_MOUSE
NC score	0.004681 (rank : 20)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	832	Shared Neighborhood Hits	4
SwissProt Accessions	Q04735	Gene names	Pctk1, Crk5
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 1) (CRK5).

EVPL_MOUSE
NC score	0.004566 (rank : 21)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	952	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

PCTK1_HUMAN
NC score	0.003031 (rank : 22)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	832	Shared Neighborhood Hits	3
SwissProt Accessions	Q00536	Gene names	PCTK1
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 1).