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Network neighborhood for query Sequence : SPSY_MOUSE

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SPSY_MOUSE
SwissProt Accessions	P97355, Q3TL65	Gene names	Sms
Domain Architecture
Description	Spermine synthase (EC 2.5.1.22) (Spermidine aminopropyltransferase) (SPMSY).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SPSY_HUMAN
θ value	0 (rank : 1)	NC score	0.997273 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	P52788, O00544, Q9UQS1	Gene names	SMS
Domain Architecture
Description	Spermine synthase (EC 2.5.1.22) (Spermidine aminopropyltransferase) (SPMSY).

SPSY_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	P97355, Q3TL65	Gene names	Sms
Domain Architecture
Description	Spermine synthase (EC 2.5.1.22) (Spermidine aminopropyltransferase) (SPMSY).

SPEE_MOUSE
θ value	1.29631e-06 (rank : 3)	NC score	0.388445 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	Q64674	Gene names	Srm
Domain Architecture
Description	Spermidine synthase (EC 2.5.1.16) (Putrescine aminopropyltransferase) (SPDSY).

SPEE_HUMAN
θ value	1.69304e-06 (rank : 4)	NC score	0.386464 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	P19623, Q15511	Gene names	SRM, SPS1
Domain Architecture
Description	Spermidine synthase (EC 2.5.1.16) (Putrescine aminopropyltransferase) (SPDSY).

KCD13_HUMAN
θ value	0.365318 (rank : 5)	NC score	0.049745 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WZ19, Q96P93, Q96SA1	Gene names	KCTD13, PDIP1, POLDIP1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD13 (Polymerase delta-interacting protein 1) (TNFAIP1-like protein).

EVPL_HUMAN
θ value	0.62314 (rank : 6)	NC score	0.032802 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	895	Shared Neighborhood Hits	4
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

SGOL2_HUMAN
θ value	0.813845 (rank : 7)	NC score	0.042852 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	207	Shared Neighborhood Hits	3
SwissProt Accessions	Q562F6, Q53RR9, Q53T20, Q86XY4, Q8IWK2, Q8IZK1, Q8N1Q5, Q96LQ3	Gene names	SGOL2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2 (Tripin).

KCD13_MOUSE
θ value	1.06291 (rank : 8)	NC score	0.045356 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGV7, Q6AXE9	Gene names	Kctd13, Poldip1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD13 (Polymerase delta-interacting protein 1).

DDX28_MOUSE
θ value	4.03905 (rank : 9)	NC score	0.012482 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

EVPL_MOUSE
θ value	5.27518 (rank : 10)	NC score	0.023727 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	952	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

CAN11_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.007757 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UMQ6, Q8N4R5	Gene names	CAPN11
Domain Architecture
Description	Calpain-11 (EC 3.4.22.-) (Calcium-activated neutral proteinase 11) (CANP 11).

PITM1_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.018363 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	O00562, Q6T7X3, Q8TBN3, Q9BZ73	Gene names	PITPNM1, DRES9, NIR2, PITPNM
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog).

PITM1_MOUSE
θ value	8.99809 (rank : 13)	NC score	0.018231 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	O35954	Gene names	Pitpnm1, Dres9, Mpt1, Nir2, Pitpnm
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Mpt-1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog 1) (RdgB1).

Hits sorted by NC score

SPSY_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	P97355, Q3TL65	Gene names	Sms
Domain Architecture
Description	Spermine synthase (EC 2.5.1.22) (Spermidine aminopropyltransferase) (SPMSY).

SPSY_HUMAN
NC score	0.997273 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	P52788, O00544, Q9UQS1	Gene names	SMS
Domain Architecture
Description	Spermine synthase (EC 2.5.1.22) (Spermidine aminopropyltransferase) (SPMSY).

SPEE_MOUSE
NC score	0.388445 (rank : 3)	θ value	1.29631e-06 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	Q64674	Gene names	Srm
Domain Architecture
Description	Spermidine synthase (EC 2.5.1.16) (Putrescine aminopropyltransferase) (SPDSY).

SPEE_HUMAN
NC score	0.386464 (rank : 4)	θ value	1.69304e-06 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	P19623, Q15511	Gene names	SRM, SPS1
Domain Architecture
Description	Spermidine synthase (EC 2.5.1.16) (Putrescine aminopropyltransferase) (SPDSY).

KCD13_HUMAN
NC score	0.049745 (rank : 5)	θ value	0.365318 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WZ19, Q96P93, Q96SA1	Gene names	KCTD13, PDIP1, POLDIP1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD13 (Polymerase delta-interacting protein 1) (TNFAIP1-like protein).

KCD13_MOUSE
NC score	0.045356 (rank : 6)	θ value	1.06291 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGV7, Q6AXE9	Gene names	Kctd13, Poldip1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD13 (Polymerase delta-interacting protein 1).

SGOL2_HUMAN
NC score	0.042852 (rank : 7)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	207	Shared Neighborhood Hits	3
SwissProt Accessions	Q562F6, Q53RR9, Q53T20, Q86XY4, Q8IWK2, Q8IZK1, Q8N1Q5, Q96LQ3	Gene names	SGOL2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2 (Tripin).

EVPL_HUMAN
NC score	0.032802 (rank : 8)	θ value	0.62314 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	895	Shared Neighborhood Hits	4
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

EVPL_MOUSE
NC score	0.023727 (rank : 9)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	952	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

PITM1_HUMAN
NC score	0.018363 (rank : 10)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	O00562, Q6T7X3, Q8TBN3, Q9BZ73	Gene names	PITPNM1, DRES9, NIR2, PITPNM
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog).

PITM1_MOUSE
NC score	0.018231 (rank : 11)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	O35954	Gene names	Pitpnm1, Dres9, Mpt1, Nir2, Pitpnm
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Mpt-1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog 1) (RdgB1).

DDX28_MOUSE
NC score	0.012482 (rank : 12)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

CAN11_HUMAN
NC score	0.007757 (rank : 13)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UMQ6, Q8N4R5	Gene names	CAPN11
Domain Architecture
Description	Calpain-11 (EC 3.4.22.-) (Calcium-activated neutral proteinase 11) (CANP 11).