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Network neighborhood for query Sequence : SIT1_HUMAN

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SIT1_HUMAN
SwissProt Accessions	Q9Y3P8	Gene names	SIT1, SIT
Domain Architecture	No domain graphic available
Description	Signaling threshold-regulating transmembrane adapter 1 precursor (Suppression-inducing transmembrane adapter 1) (SHP2-interacting transmembrane adapter protein) (gp30/40).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SIT1_HUMAN
θ value	1.13764e-111 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y3P8	Gene names	SIT1, SIT
Domain Architecture	No domain graphic available
Description	Signaling threshold-regulating transmembrane adapter 1 precursor (Suppression-inducing transmembrane adapter 1) (SHP2-interacting transmembrane adapter protein) (gp30/40).

SIT1_MOUSE
θ value	5.71191e-71 (rank : 2)	NC score	0.979698 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C503, Q9WUU5	Gene names	Sit1, Sit
Domain Architecture	No domain graphic available
Description	Signaling threshold-regulating transmembrane adapter 1 (Suppression- inducing transmembrane adapter 1) (SHP2-interacting transmembrane adapter protein).

TRAT1_MOUSE
θ value	0.365318 (rank : 3)	NC score	0.102207 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UU67, Q3SXD9, Q3SXE0	Gene names	Trat1
Domain Architecture	No domain graphic available
Description	T-cell receptor-associated transmembrane adapter 1 (T-cell receptor- interacting molecule) (TRIM).

B2L12_HUMAN
θ value	0.47712 (rank : 4)	NC score	0.101780 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HB09, Q3SY11, Q96I96, Q9HB08	Gene names	BCL2L12, BPR
Domain Architecture	No domain graphic available
Description	Bcl-2-related proline-rich protein (Bcl-2-like 12 protein).

SYN1_MOUSE
θ value	1.38821 (rank : 5)	NC score	0.029648 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	363	Shared Neighborhood Hits	5
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

K1802_HUMAN
θ value	1.81305 (rank : 6)	NC score	0.019928 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	1378	Shared Neighborhood Hits	8
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

B3GT4_MOUSE
θ value	4.03905 (rank : 7)	NC score	0.022407 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0F0, Q91VC1, Q920U8, Q920U9	Gene names	B3galt4
Domain Architecture
Description	Beta-1,3-galactosyltransferase 4 (EC 2.4.1.62) (Beta-1,3-GalTase 4) (Beta3Gal-T4) (b3Gal-T4) (Ganglioside galactosyltransferase) (UDP- galactose:beta-N-acetyl-galactosamine-beta-1,3-galactosyltransferase) (GAL-T2).

CASC3_HUMAN
θ value	5.27518 (rank : 8)	NC score	0.026247 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	204	Shared Neighborhood Hits	2
SwissProt Accessions	O15234	Gene names	CASC3, MLN51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node protein 51) (Protein MLN 51) (Protein barentsz) (Btz).

NKX31_HUMAN
θ value	6.88961 (rank : 9)	NC score	0.006587 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	331	Shared Neighborhood Hits	2
SwissProt Accessions	Q99801, O15465, Q9H2P4, Q9H2P5, Q9H2P6, Q9H2P7, Q9HBG0	Gene names	NKX3-1, NKX3.1, NKX3A
Domain Architecture
Description	Homeobox protein Nkx-3.1.

TRAT1_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.067837 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PIZ9, Q9NZX5	Gene names	TRAT1, TCRIM
Domain Architecture	No domain graphic available
Description	T-cell receptor-associated transmembrane adapter 1 (T-cell receptor- interacting molecule) (TRIM) (pp29/30).

AATK_HUMAN
θ value	8.99809 (rank : 11)	NC score	0.003614 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	1243	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

K1849_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.012099 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	220	Shared Neighborhood Hits	3
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

MLL2_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.009464 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	1788	Shared Neighborhood Hits	8
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PRGC2_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.018344 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	272	Shared Neighborhood Hits	6
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

PTN23_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.007765 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	646	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

TARA_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.009862 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	1626	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ZSWM4_MOUSE
θ value	8.99809 (rank : 17)	NC score	0.014199 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C7B8, Q8BPN9	Gene names	Zswim4
Domain Architecture	No domain graphic available
Description	Zinc finger SWIM domain-containing protein 4.

Hits sorted by NC score

SIT1_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.13764e-111 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y3P8	Gene names	SIT1, SIT
Domain Architecture	No domain graphic available
Description	Signaling threshold-regulating transmembrane adapter 1 precursor (Suppression-inducing transmembrane adapter 1) (SHP2-interacting transmembrane adapter protein) (gp30/40).

SIT1_MOUSE
NC score	0.979698 (rank : 2)	θ value	5.71191e-71 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C503, Q9WUU5	Gene names	Sit1, Sit
Domain Architecture	No domain graphic available
Description	Signaling threshold-regulating transmembrane adapter 1 (Suppression- inducing transmembrane adapter 1) (SHP2-interacting transmembrane adapter protein).

TRAT1_MOUSE
NC score	0.102207 (rank : 3)	θ value	0.365318 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UU67, Q3SXD9, Q3SXE0	Gene names	Trat1
Domain Architecture	No domain graphic available
Description	T-cell receptor-associated transmembrane adapter 1 (T-cell receptor- interacting molecule) (TRIM).

B2L12_HUMAN
NC score	0.101780 (rank : 4)	θ value	0.47712 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HB09, Q3SY11, Q96I96, Q9HB08	Gene names	BCL2L12, BPR
Domain Architecture	No domain graphic available
Description	Bcl-2-related proline-rich protein (Bcl-2-like 12 protein).

TRAT1_HUMAN
NC score	0.067837 (rank : 5)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PIZ9, Q9NZX5	Gene names	TRAT1, TCRIM
Domain Architecture	No domain graphic available
Description	T-cell receptor-associated transmembrane adapter 1 (T-cell receptor- interacting molecule) (TRIM) (pp29/30).

SYN1_MOUSE
NC score	0.029648 (rank : 6)	θ value	1.38821 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	363	Shared Neighborhood Hits	5
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

CASC3_HUMAN
NC score	0.026247 (rank : 7)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	204	Shared Neighborhood Hits	2
SwissProt Accessions	O15234	Gene names	CASC3, MLN51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node protein 51) (Protein MLN 51) (Protein barentsz) (Btz).

B3GT4_MOUSE
NC score	0.022407 (rank : 8)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0F0, Q91VC1, Q920U8, Q920U9	Gene names	B3galt4
Domain Architecture
Description	Beta-1,3-galactosyltransferase 4 (EC 2.4.1.62) (Beta-1,3-GalTase 4) (Beta3Gal-T4) (b3Gal-T4) (Ganglioside galactosyltransferase) (UDP- galactose:beta-N-acetyl-galactosamine-beta-1,3-galactosyltransferase) (GAL-T2).

K1802_HUMAN
NC score	0.019928 (rank : 9)	θ value	1.81305 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	1378	Shared Neighborhood Hits	8
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PRGC2_HUMAN
NC score	0.018344 (rank : 10)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	272	Shared Neighborhood Hits	6
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

ZSWM4_MOUSE
NC score	0.014199 (rank : 11)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C7B8, Q8BPN9	Gene names	Zswim4
Domain Architecture	No domain graphic available
Description	Zinc finger SWIM domain-containing protein 4.

K1849_HUMAN
NC score	0.012099 (rank : 12)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	220	Shared Neighborhood Hits	3
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

TARA_HUMAN
NC score	0.009862 (rank : 13)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	1626	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

MLL2_HUMAN
NC score	0.009464 (rank : 14)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	1788	Shared Neighborhood Hits	8
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PTN23_HUMAN
NC score	0.007765 (rank : 15)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	646	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

NKX31_HUMAN
NC score	0.006587 (rank : 16)	θ value	6.88961 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	331	Shared Neighborhood Hits	2
SwissProt Accessions	Q99801, O15465, Q9H2P4, Q9H2P5, Q9H2P6, Q9H2P7, Q9HBG0	Gene names	NKX3-1, NKX3.1, NKX3A
Domain Architecture
Description	Homeobox protein Nkx-3.1.

AATK_HUMAN
NC score	0.003614 (rank : 17)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	1243	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).