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Network neighborhood for query Sequence : PRIO_HUMAN

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PRIO_HUMAN
SwissProt Accessions	P04156, O60489, P78446, Q15216, Q15221, Q8TBG0, Q96E70, Q9UP19	Gene names	PRNP, PRP
Domain Architecture
Description	Major prion protein precursor (PrP) (PrP27-30) (PrP33-35C) (ASCR) (CD230 antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PRIO_HUMAN
θ value	1.71185e-83 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	P04156, O60489, P78446, Q15216, Q15221, Q8TBG0, Q96E70, Q9UP19	Gene names	PRNP, PRP
Domain Architecture
Description	Major prion protein precursor (PrP) (PrP27-30) (PrP33-35C) (ASCR) (CD230 antigen).

PRIO_MOUSE
θ value	1.22964e-73 (rank : 2)	NC score	0.990554 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	P04925	Gene names	Prnp, Prn-p, Prp
Domain Architecture
Description	Major prion protein precursor (PrP) (PrP27-30) (PrP33-35C) (CD230 antigen).

PRND_HUMAN
θ value	0.00175202 (rank : 3)	NC score	0.272399 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKY0, Q9H311, Q9H312, Q9NTM4	Gene names	PRND, DPL
Domain Architecture
Description	Prion-like protein doppel precursor (PrPLP) (Prion protein 2).

PRND_MOUSE
θ value	0.00869519 (rank : 4)	NC score	0.274673 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QUG3, Q9QZT5	Gene names	Prnd
Domain Architecture
Description	Prion-like protein doppel precursor (PrPLP) (Doppelganger).

CF015_HUMAN
θ value	0.0252991 (rank : 5)	NC score	0.209499 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q6UXA7, Q5SQ81, Q86Z05, Q9UIG3	Gene names	C6orf15, STG
Domain Architecture	No domain graphic available
Description	Protein C6orf15 precursor (Protein STG).

I5P2_HUMAN
θ value	0.813845 (rank : 6)	NC score	0.063056 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

TIA1_MOUSE
θ value	1.06291 (rank : 7)	NC score	0.036133 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	241	Shared Neighborhood Hits	3
SwissProt Accessions	P52912	Gene names	Tia1, Tia
Domain Architecture
Description	Nucleolysin TIA-1 (RNA-binding protein TIA-1).

TSSC4_HUMAN
θ value	1.81305 (rank : 8)	NC score	0.072363 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5U2, Q86VL2, Q9BRS6	Gene names	TSSC4
Domain Architecture	No domain graphic available
Description	Protein TSSC4 (Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein) (Tumor-suppressing STF cDNA 4 protein).

TGON2_MOUSE
θ value	2.36792 (rank : 9)	NC score	0.050730 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	277	Shared Neighborhood Hits	3
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

TRHDE_HUMAN
θ value	3.0926 (rank : 10)	NC score	0.018322 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UKU6, Q6UWJ4	Gene names	TRHDE
Domain Architecture
Description	Thyrotropin-releasing hormone-degrading ectoenzyme (EC 3.4.19.6) (TRH- degrading ectoenzyme) (TRH-DE) (TRH-specific aminopeptidase) (Thyroliberinase) (Pyroglutamyl-peptidase II) (PAP-II).

AUXI_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.021984 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TZ3, Q6P2K9, Q8C7L9	Gene names	Dnajc6, Kiaa0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

Hits sorted by NC score

PRIO_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.71185e-83 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	P04156, O60489, P78446, Q15216, Q15221, Q8TBG0, Q96E70, Q9UP19	Gene names	PRNP, PRP
Domain Architecture
Description	Major prion protein precursor (PrP) (PrP27-30) (PrP33-35C) (ASCR) (CD230 antigen).

PRIO_MOUSE
NC score	0.990554 (rank : 2)	θ value	1.22964e-73 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	P04925	Gene names	Prnp, Prn-p, Prp
Domain Architecture
Description	Major prion protein precursor (PrP) (PrP27-30) (PrP33-35C) (CD230 antigen).

PRND_MOUSE
NC score	0.274673 (rank : 3)	θ value	0.00869519 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QUG3, Q9QZT5	Gene names	Prnd
Domain Architecture
Description	Prion-like protein doppel precursor (PrPLP) (Doppelganger).

PRND_HUMAN
NC score	0.272399 (rank : 4)	θ value	0.00175202 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKY0, Q9H311, Q9H312, Q9NTM4	Gene names	PRND, DPL
Domain Architecture
Description	Prion-like protein doppel precursor (PrPLP) (Prion protein 2).

CF015_HUMAN
NC score	0.209499 (rank : 5)	θ value	0.0252991 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q6UXA7, Q5SQ81, Q86Z05, Q9UIG3	Gene names	C6orf15, STG
Domain Architecture	No domain graphic available
Description	Protein C6orf15 precursor (Protein STG).

TSSC4_HUMAN
NC score	0.072363 (rank : 6)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5U2, Q86VL2, Q9BRS6	Gene names	TSSC4
Domain Architecture	No domain graphic available
Description	Protein TSSC4 (Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein) (Tumor-suppressing STF cDNA 4 protein).

I5P2_HUMAN
NC score	0.063056 (rank : 7)	θ value	0.813845 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

TGON2_MOUSE
NC score	0.050730 (rank : 8)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	277	Shared Neighborhood Hits	3
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

TIA1_MOUSE
NC score	0.036133 (rank : 9)	θ value	1.06291 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	241	Shared Neighborhood Hits	3
SwissProt Accessions	P52912	Gene names	Tia1, Tia
Domain Architecture
Description	Nucleolysin TIA-1 (RNA-binding protein TIA-1).

AUXI_MOUSE
NC score	0.021984 (rank : 10)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TZ3, Q6P2K9, Q8C7L9	Gene names	Dnajc6, Kiaa0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

TRHDE_HUMAN
NC score	0.018322 (rank : 11)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UKU6, Q6UWJ4	Gene names	TRHDE
Domain Architecture
Description	Thyrotropin-releasing hormone-degrading ectoenzyme (EC 3.4.19.6) (TRH- degrading ectoenzyme) (TRH-DE) (TRH-specific aminopeptidase) (Thyroliberinase) (Pyroglutamyl-peptidase II) (PAP-II).