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Network neighborhood for query Sequence : OXLA_HUMAN

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OXLA_HUMAN
SwissProt Accessions	Q96RQ9, Q4GZN1, Q4GZN2, Q6P2Q3, Q8TEM5, Q96RQ8	Gene names	IL4I1, FIG1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (hFIG1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

OXLA_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q96RQ9, Q4GZN1, Q4GZN2, Q6P2Q3, Q8TEM5, Q96RQ8	Gene names	IL4I1, FIG1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (hFIG1).

OXLA_MOUSE
θ value	0 (rank : 2)	NC score	0.980060 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	O09046, Q3T9N9, Q3U7S6, Q3V0K2, Q6Y632, Q6YBV6, Q6YDI8, Q8R2G8, Q9CXK7	Gene names	Il4i1, Fig1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (mFIG1).

AOFB_HUMAN
θ value	2.28291e-11 (rank : 3)	NC score	0.487189 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	P27338, Q7Z6S2	Gene names	MAOB
Domain Architecture
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

AOFA_MOUSE
θ value	7.34386e-10 (rank : 4)	NC score	0.470552 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	37	Shared Neighborhood Hits	21
SwissProt Accessions	Q64133, Q8K0Z8	Gene names	Maoa
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

AOFB_MOUSE
θ value	1.17247e-07 (rank : 5)	NC score	0.468630 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	28	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BW75, Q8C0B2	Gene names	Maob
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

AOFA_HUMAN
θ value	1.69304e-06 (rank : 6)	NC score	0.437548 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	P21397, Q16426	Gene names	MAOA
Domain Architecture
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

LSD1_HUMAN
θ value	0.00020696 (rank : 7)	NC score	0.320716 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	455	Shared Neighborhood Hits	26
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

LSD1_MOUSE
θ value	0.00020696 (rank : 8)	NC score	0.335591 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	224	Shared Neighborhood Hits	26
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

ERG1_MOUSE
θ value	0.00509761 (rank : 9)	NC score	0.174434 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	P52019	Gene names	Sqle, Erg1
Domain Architecture
Description	Squalene monooxygenase (EC 1.14.99.7) (Squalene epoxidase) (SE).

PAOX_HUMAN
θ value	0.00665767 (rank : 10)	NC score	0.275961 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	Q6QHF9, Q6QHF5, Q6QHF6, Q6QHF7, Q6QHF8, Q6QHG0, Q6QHG1, Q6QHG2, Q6QHG3, Q6QHG4, Q6QHG5, Q6QHG6, Q86WP9, Q8N555, Q8NCX3	Gene names	PAOX, PAO
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

AOF1_HUMAN
θ value	0.00869519 (rank : 11)	NC score	0.338107 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	53	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NB78, Q5TGV3, Q6AI15, Q6ZUU4, Q8N258, Q96EL7	Gene names	AOF1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

PAOX_MOUSE
θ value	0.0113563 (rank : 12)	NC score	0.298056 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	25	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C0L6, Q8K254	Gene names	Paox, Pao
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

SMOX_MOUSE
θ value	0.0193708 (rank : 13)	NC score	0.257782 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q99K82, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57	Gene names	Smox, Smo
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

SMOX_HUMAN
θ value	0.0330416 (rank : 14)	NC score	0.257739 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	35	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NWM0, Q5TE26, Q5TE27, Q6UY28, Q8IX00, Q96LC3, Q96LC4, Q96QT3, Q9BW38, Q9H6H1, Q9NP51, Q9NPY1, Q9NPY2	Gene names	SMOX, C20orf16, SMO
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

AOF1_MOUSE
θ value	0.0961366 (rank : 15)	NC score	0.337601 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	51	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CIG3, Q8C5C4, Q8CEC1	Gene names	Aof1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

ERG1_HUMAN
θ value	0.0961366 (rank : 16)	NC score	0.149275 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q14534, Q9UEK6	Gene names	SQLE, ERG1
Domain Architecture
Description	Squalene monooxygenase (EC 1.14.99.7) (Squalene epoxidase) (SE).

PPOX_HUMAN
θ value	0.0961366 (rank : 17)	NC score	0.184382 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	P50336	Gene names	PPOX
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

FMO2_MOUSE
θ value	0.163984 (rank : 18)	NC score	0.099366 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	23	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K2I3, Q9QZF7	Gene names	Fmo2
Domain Architecture	No domain graphic available
Description	Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2).

CJ033_MOUSE
θ value	0.279714 (rank : 19)	NC score	0.133498 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	33	Shared Neighborhood Hits	18
SwissProt Accessions	Q3U4I7, Q8CAN2, Q9D630	Gene names
Domain Architecture	No domain graphic available
Description	Probable oxidoreductase C10orf33 homolog (EC 1.-.-.-).

GSHR_MOUSE
θ value	0.279714 (rank : 20)	NC score	0.068897 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	P47791, Q7TNC2, Q8BN97, Q8C9Z6	Gene names	Gsr, Gr1
Domain Architecture
Description	Glutathione reductase, mitochondrial precursor (EC 1.8.1.7) (GR) (GRase).

FMO2_HUMAN
θ value	0.47712 (rank : 21)	NC score	0.090645 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	Q99518, Q5EBX4, Q9BRX1	Gene names	FMO2
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1).

FMO1_HUMAN
θ value	1.38821 (rank : 22)	NC score	0.085498 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q01740, Q5QPT2, Q9UJC2	Gene names	FMO1
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 1 (EC 1.14.13.8) (Fetal hepatic flavin-containing monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1).

FMO1_MOUSE
θ value	1.38821 (rank : 23)	NC score	0.080624 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	P50285	Gene names	Fmo1, Fmo-1
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 1 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1).

DLDH_HUMAN
θ value	1.81305 (rank : 24)	NC score	0.076707 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	34	Shared Neighborhood Hits	14
SwissProt Accessions	P09622, Q14131, Q14167	Gene names	DLD, GCSL, LAD, PHE3
Domain Architecture
Description	Dihydrolipoyl dehydrogenase, mitochondrial precursor (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein).

DLDH_MOUSE
θ value	1.81305 (rank : 25)	NC score	0.076711 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	35	Shared Neighborhood Hits	14
SwissProt Accessions	O08749	Gene names	Dld
Domain Architecture
Description	Dihydrolipoyl dehydrogenase, mitochondrial precursor (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase).

FMO3_HUMAN
θ value	1.81305 (rank : 26)	NC score	0.089602 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	P31513, Q14854, Q8N5N5	Gene names	FMO3
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3) (FMO form 2) (FMO II).

PPOX_MOUSE
θ value	1.81305 (rank : 27)	NC score	0.131166 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	P51175, P97344, Q99M34	Gene names	Ppox
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

CJ033_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.111051 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	26	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N2H3, Q5TAA9, Q9BRQ1	Gene names	C10orf33
Domain Architecture	No domain graphic available
Description	Probable oxidoreductase C10orf33 (EC 1.-.-.-).

ANM6_MOUSE
θ value	3.0926 (rank : 29)	NC score	0.022094 (rank : 38)
Query Neighborhood Hits	36	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NZB1, Q3TA42, Q8BN52, Q8BSC2, Q8R5D7	Gene names	Prmt6, Hrmt1l6
Domain Architecture	No domain graphic available
Description	Protein arginine N-methyltransferase 6 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6).

FMO3_MOUSE
θ value	4.03905 (rank : 30)	NC score	0.091542 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	P97501	Gene names	Fmo3
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3).

PCYOX_MOUSE
θ value	4.03905 (rank : 31)	NC score	0.074169 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CQF9, Q3UHV6, Q69ZW0, Q8BZX1	Gene names	Pcyox1, Kiaa0908
Domain Architecture	No domain graphic available
Description	Prenylcysteine oxidase precursor (EC 1.8.3.5).

GSHR_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.051468 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	P00390, Q7Z5C9, Q9NP63	Gene names	GSR, GLUR, GRD1
Domain Architecture
Description	Glutathione reductase, mitochondrial precursor (EC 1.8.1.7) (GR) (GRase).

K0423_MOUSE
θ value	5.27518 (rank : 33)	NC score	0.018893 (rank : 39)
Query Neighborhood Hits	36	Target Neighborhood Hits	115	Shared Neighborhood Hits	2
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

CHDH_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.030625 (rank : 37)
Query Neighborhood Hits	36	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BJ64, Q8CHT7	Gene names	Chdh
Domain Architecture
Description	Choline dehydrogenase, mitochondrial precursor (EC 1.1.99.1) (CHD) (CDH).

FMO4_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.073877 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	25	Shared Neighborhood Hits	16
SwissProt Accessions	P31512	Gene names	FMO4, FMO2
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 4 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 4) (FMO 4) (Dimethylaniline oxidase 4).

ANM6_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.017581 (rank : 40)
Query Neighborhood Hits	36	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q96LA8, Q6DKI4, Q9NVR8	Gene names	PRMT6, HRMT1L6
Domain Architecture
Description	Protein arginine N-methyltransferase 6 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6).

FMO4_MOUSE
θ value	θ > 10 (rank : 37)	NC score	0.061970 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VHG0	Gene names	Fmo4
Domain Architecture	No domain graphic available
Description	Dimethylaniline monooxygenase [N-oxide-forming] 4 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 4) (FMO 4) (Dimethylaniline oxidase 4).

FMO5_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.061771 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	P49326	Gene names	FMO5
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5).

FMO5_MOUSE
θ value	θ > 10 (rank : 39)	NC score	0.057586 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	20	Shared Neighborhood Hits	9
SwissProt Accessions	P97872	Gene names	Fmo5
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5).

FMO6_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.063455 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	O60774	Gene names	FMO6
Domain Architecture
Description	Putative dimethylaniline monooxygenase [N-oxide-forming] 6 (EC 1.14.13.8) (Flavin-containing monooxygenase 6) (FMO 6) (Dimethylaniline oxidase 6).

Hits sorted by NC score

OXLA_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q96RQ9, Q4GZN1, Q4GZN2, Q6P2Q3, Q8TEM5, Q96RQ8	Gene names	IL4I1, FIG1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (hFIG1).

OXLA_MOUSE
NC score	0.980060 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	O09046, Q3T9N9, Q3U7S6, Q3V0K2, Q6Y632, Q6YBV6, Q6YDI8, Q8R2G8, Q9CXK7	Gene names	Il4i1, Fig1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (mFIG1).

AOFB_HUMAN
NC score	0.487189 (rank : 3)	θ value	2.28291e-11 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	P27338, Q7Z6S2	Gene names	MAOB
Domain Architecture
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

AOFA_MOUSE
NC score	0.470552 (rank : 4)	θ value	7.34386e-10 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	37	Shared Neighborhood Hits	21
SwissProt Accessions	Q64133, Q8K0Z8	Gene names	Maoa
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

AOFB_MOUSE
NC score	0.468630 (rank : 5)	θ value	1.17247e-07 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	28	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BW75, Q8C0B2	Gene names	Maob
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

AOFA_HUMAN
NC score	0.437548 (rank : 6)	θ value	1.69304e-06 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	P21397, Q16426	Gene names	MAOA
Domain Architecture
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

AOF1_HUMAN
NC score	0.338107 (rank : 7)	θ value	0.00869519 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	53	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NB78, Q5TGV3, Q6AI15, Q6ZUU4, Q8N258, Q96EL7	Gene names	AOF1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

AOF1_MOUSE
NC score	0.337601 (rank : 8)	θ value	0.0961366 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	51	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CIG3, Q8C5C4, Q8CEC1	Gene names	Aof1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

LSD1_MOUSE
NC score	0.335591 (rank : 9)	θ value	0.00020696 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	224	Shared Neighborhood Hits	26
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

LSD1_HUMAN
NC score	0.320716 (rank : 10)	θ value	0.00020696 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	455	Shared Neighborhood Hits	26
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

PAOX_MOUSE
NC score	0.298056 (rank : 11)	θ value	0.0113563 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	25	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C0L6, Q8K254	Gene names	Paox, Pao
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

PAOX_HUMAN
NC score	0.275961 (rank : 12)	θ value	0.00665767 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	Q6QHF9, Q6QHF5, Q6QHF6, Q6QHF7, Q6QHF8, Q6QHG0, Q6QHG1, Q6QHG2, Q6QHG3, Q6QHG4, Q6QHG5, Q6QHG6, Q86WP9, Q8N555, Q8NCX3	Gene names	PAOX, PAO
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

SMOX_MOUSE
NC score	0.257782 (rank : 13)	θ value	0.0193708 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q99K82, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57	Gene names	Smox, Smo
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

SMOX_HUMAN
NC score	0.257739 (rank : 14)	θ value	0.0330416 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	35	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NWM0, Q5TE26, Q5TE27, Q6UY28, Q8IX00, Q96LC3, Q96LC4, Q96QT3, Q9BW38, Q9H6H1, Q9NP51, Q9NPY1, Q9NPY2	Gene names	SMOX, C20orf16, SMO
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

PPOX_HUMAN
NC score	0.184382 (rank : 15)	θ value	0.0961366 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	P50336	Gene names	PPOX
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

ERG1_MOUSE
NC score	0.174434 (rank : 16)	θ value	0.00509761 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	P52019	Gene names	Sqle, Erg1
Domain Architecture
Description	Squalene monooxygenase (EC 1.14.99.7) (Squalene epoxidase) (SE).

ERG1_HUMAN
NC score	0.149275 (rank : 17)	θ value	0.0961366 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q14534, Q9UEK6	Gene names	SQLE, ERG1
Domain Architecture
Description	Squalene monooxygenase (EC 1.14.99.7) (Squalene epoxidase) (SE).

CJ033_MOUSE
NC score	0.133498 (rank : 18)	θ value	0.279714 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	33	Shared Neighborhood Hits	18
SwissProt Accessions	Q3U4I7, Q8CAN2, Q9D630	Gene names
Domain Architecture	No domain graphic available
Description	Probable oxidoreductase C10orf33 homolog (EC 1.-.-.-).

PPOX_MOUSE
NC score	0.131166 (rank : 19)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	P51175, P97344, Q99M34	Gene names	Ppox
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

CJ033_HUMAN
NC score	0.111051 (rank : 20)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	26	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N2H3, Q5TAA9, Q9BRQ1	Gene names	C10orf33
Domain Architecture	No domain graphic available
Description	Probable oxidoreductase C10orf33 (EC 1.-.-.-).

FMO2_MOUSE
NC score	0.099366 (rank : 21)	θ value	0.163984 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	23	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K2I3, Q9QZF7	Gene names	Fmo2
Domain Architecture	No domain graphic available
Description	Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2).

FMO3_MOUSE
NC score	0.091542 (rank : 22)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	P97501	Gene names	Fmo3
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3).

FMO2_HUMAN
NC score	0.090645 (rank : 23)	θ value	0.47712 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	Q99518, Q5EBX4, Q9BRX1	Gene names	FMO2
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1).

FMO3_HUMAN
NC score	0.089602 (rank : 24)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	P31513, Q14854, Q8N5N5	Gene names	FMO3
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3) (FMO form 2) (FMO II).

FMO1_HUMAN
NC score	0.085498 (rank : 25)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q01740, Q5QPT2, Q9UJC2	Gene names	FMO1
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 1 (EC 1.14.13.8) (Fetal hepatic flavin-containing monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1).

FMO1_MOUSE
NC score	0.080624 (rank : 26)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	P50285	Gene names	Fmo1, Fmo-1
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 1 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1).

DLDH_MOUSE
NC score	0.076711 (rank : 27)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	35	Shared Neighborhood Hits	14
SwissProt Accessions	O08749	Gene names	Dld
Domain Architecture
Description	Dihydrolipoyl dehydrogenase, mitochondrial precursor (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase).

DLDH_HUMAN
NC score	0.076707 (rank : 28)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	34	Shared Neighborhood Hits	14
SwissProt Accessions	P09622, Q14131, Q14167	Gene names	DLD, GCSL, LAD, PHE3
Domain Architecture
Description	Dihydrolipoyl dehydrogenase, mitochondrial precursor (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein).

PCYOX_MOUSE
NC score	0.074169 (rank : 29)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CQF9, Q3UHV6, Q69ZW0, Q8BZX1	Gene names	Pcyox1, Kiaa0908
Domain Architecture	No domain graphic available
Description	Prenylcysteine oxidase precursor (EC 1.8.3.5).

FMO4_HUMAN
NC score	0.073877 (rank : 30)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	25	Shared Neighborhood Hits	16
SwissProt Accessions	P31512	Gene names	FMO4, FMO2
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 4 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 4) (FMO 4) (Dimethylaniline oxidase 4).

GSHR_MOUSE
NC score	0.068897 (rank : 31)	θ value	0.279714 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	P47791, Q7TNC2, Q8BN97, Q8C9Z6	Gene names	Gsr, Gr1
Domain Architecture
Description	Glutathione reductase, mitochondrial precursor (EC 1.8.1.7) (GR) (GRase).

FMO6_HUMAN
NC score	0.063455 (rank : 32)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	36	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	O60774	Gene names	FMO6
Domain Architecture
Description	Putative dimethylaniline monooxygenase [N-oxide-forming] 6 (EC 1.14.13.8) (Flavin-containing monooxygenase 6) (FMO 6) (Dimethylaniline oxidase 6).

FMO4_MOUSE
NC score	0.061970 (rank : 33)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	36	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VHG0	Gene names	Fmo4
Domain Architecture	No domain graphic available
Description	Dimethylaniline monooxygenase [N-oxide-forming] 4 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 4) (FMO 4) (Dimethylaniline oxidase 4).

FMO5_HUMAN
NC score	0.061771 (rank : 34)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	36	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	P49326	Gene names	FMO5
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5).

FMO5_MOUSE
NC score	0.057586 (rank : 35)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	36	Target Neighborhood Hits	20	Shared Neighborhood Hits	9
SwissProt Accessions	P97872	Gene names	Fmo5
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5).

GSHR_HUMAN
NC score	0.051468 (rank : 36)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	P00390, Q7Z5C9, Q9NP63	Gene names	GSR, GLUR, GRD1
Domain Architecture
Description	Glutathione reductase, mitochondrial precursor (EC 1.8.1.7) (GR) (GRase).

CHDH_MOUSE
NC score	0.030625 (rank : 37)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BJ64, Q8CHT7	Gene names	Chdh
Domain Architecture
Description	Choline dehydrogenase, mitochondrial precursor (EC 1.1.99.1) (CHD) (CDH).

ANM6_MOUSE
NC score	0.022094 (rank : 38)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NZB1, Q3TA42, Q8BN52, Q8BSC2, Q8R5D7	Gene names	Prmt6, Hrmt1l6
Domain Architecture	No domain graphic available
Description	Protein arginine N-methyltransferase 6 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6).

K0423_MOUSE
NC score	0.018893 (rank : 39)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	115	Shared Neighborhood Hits	2
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

ANM6_HUMAN
NC score	0.017581 (rank : 40)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q96LA8, Q6DKI4, Q9NVR8	Gene names	PRMT6, HRMT1L6
Domain Architecture
Description	Protein arginine N-methyltransferase 6 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6).