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Network neighborhood for query Sequence : ORC6_MOUSE

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ORC6_MOUSE
SwissProt Accessions	Q9WUJ8	Gene names	Orc6l, Orc6
Domain Architecture
Description	Origin recognition complex subunit 6.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ORC6_MOUSE
θ value	5.05951e-144 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WUJ8	Gene names	Orc6l, Orc6
Domain Architecture
Description	Origin recognition complex subunit 6.

ORC6_HUMAN
θ value	5.11853e-104 (rank : 2)	NC score	0.978015 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5N6	Gene names	ORC6L
Domain Architecture
Description	Origin recognition complex subunit 6.

PCNT_HUMAN
θ value	0.163984 (rank : 3)	NC score	0.033338 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	1551	Shared Neighborhood Hits	12
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

LHX2_HUMAN
θ value	0.365318 (rank : 4)	NC score	0.032905 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	432	Shared Neighborhood Hits	3
SwissProt Accessions	P50458, O95860, Q8N1Z3	Gene names	LHX2, LH2
Domain Architecture
Description	LIM/homeobox protein Lhx2 (Homeobox protein LH-2).

LHX2_MOUSE
θ value	0.365318 (rank : 5)	NC score	0.033002 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	431	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0S2	Gene names	Lhx2
Domain Architecture
Description	LIM/homeobox protein Lhx2.

IBRD2_HUMAN
θ value	0.813845 (rank : 6)	NC score	0.052300 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

IBRD2_MOUSE
θ value	0.813845 (rank : 7)	NC score	0.053209 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

CU013_HUMAN
θ value	1.06291 (rank : 8)	NC score	0.043614 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	405	Shared Neighborhood Hits	10
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

KINH_HUMAN
θ value	1.81305 (rank : 9)	NC score	0.017450 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	1231	Shared Neighborhood Hits	12
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

XE7_HUMAN
θ value	1.81305 (rank : 10)	NC score	0.030438 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	738	Shared Neighborhood Hits	11
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

MYO15_HUMAN
θ value	2.36792 (rank : 11)	NC score	0.016484 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	671	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

DDX58_HUMAN
θ value	3.0926 (rank : 12)	NC score	0.023080 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

NUMA1_HUMAN
θ value	4.03905 (rank : 13)	NC score	0.020064 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	1523	Shared Neighborhood Hits	16
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

KINH_MOUSE
θ value	5.27518 (rank : 14)	NC score	0.016422 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	1082	Shared Neighborhood Hits	11
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

MYO15_MOUSE
θ value	5.27518 (rank : 15)	NC score	0.015254 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	467	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

CIP4_HUMAN
θ value	6.88961 (rank : 16)	NC score	0.022836 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	374	Shared Neighborhood Hits	6
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

SMC1A_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.016649 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	1346	Shared Neighborhood Hits	12
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	6.88961 (rank : 18)	NC score	0.016135 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	1384	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

EP15_HUMAN
θ value	8.99809 (rank : 19)	NC score	0.011894 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	1021	Shared Neighborhood Hits	9
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

NEBU_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.013286 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	420	Shared Neighborhood Hits	7
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

PRP40_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.022284 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	442	Shared Neighborhood Hits	7
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
θ value	8.99809 (rank : 22)	NC score	0.021757 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	447	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

TLN1_HUMAN
θ value	8.99809 (rank : 23)	NC score	0.010690 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	218	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

Hits sorted by NC score

ORC6_MOUSE
NC score	0.999962 (rank : 1)	θ value	5.05951e-144 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WUJ8	Gene names	Orc6l, Orc6
Domain Architecture
Description	Origin recognition complex subunit 6.

ORC6_HUMAN
NC score	0.978015 (rank : 2)	θ value	5.11853e-104 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5N6	Gene names	ORC6L
Domain Architecture
Description	Origin recognition complex subunit 6.

IBRD2_MOUSE
NC score	0.053209 (rank : 3)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

IBRD2_HUMAN
NC score	0.052300 (rank : 4)	θ value	0.813845 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

CU013_HUMAN
NC score	0.043614 (rank : 5)	θ value	1.06291 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	405	Shared Neighborhood Hits	10
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

PCNT_HUMAN
NC score	0.033338 (rank : 6)	θ value	0.163984 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	1551	Shared Neighborhood Hits	12
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

LHX2_MOUSE
NC score	0.033002 (rank : 7)	θ value	0.365318 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	431	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0S2	Gene names	Lhx2
Domain Architecture
Description	LIM/homeobox protein Lhx2.

LHX2_HUMAN
NC score	0.032905 (rank : 8)	θ value	0.365318 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	432	Shared Neighborhood Hits	3
SwissProt Accessions	P50458, O95860, Q8N1Z3	Gene names	LHX2, LH2
Domain Architecture
Description	LIM/homeobox protein Lhx2 (Homeobox protein LH-2).

XE7_HUMAN
NC score	0.030438 (rank : 9)	θ value	1.81305 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	738	Shared Neighborhood Hits	11
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

DDX58_HUMAN
NC score	0.023080 (rank : 10)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

CIP4_HUMAN
NC score	0.022836 (rank : 11)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	374	Shared Neighborhood Hits	6
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

PRP40_HUMAN
NC score	0.022284 (rank : 12)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	442	Shared Neighborhood Hits	7
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
NC score	0.021757 (rank : 13)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	447	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

NUMA1_HUMAN
NC score	0.020064 (rank : 14)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	1523	Shared Neighborhood Hits	16
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

KINH_HUMAN
NC score	0.017450 (rank : 15)	θ value	1.81305 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	1231	Shared Neighborhood Hits	12
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

SMC1A_HUMAN
NC score	0.016649 (rank : 16)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	1346	Shared Neighborhood Hits	12
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

MYO15_HUMAN
NC score	0.016484 (rank : 17)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	671	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

KINH_MOUSE
NC score	0.016422 (rank : 18)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	1082	Shared Neighborhood Hits	11
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

SMC1A_MOUSE
NC score	0.016135 (rank : 19)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	1384	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

MYO15_MOUSE
NC score	0.015254 (rank : 20)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	467	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NEBU_HUMAN
NC score	0.013286 (rank : 21)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	420	Shared Neighborhood Hits	7
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

EP15_HUMAN
NC score	0.011894 (rank : 22)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	1021	Shared Neighborhood Hits	9
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

TLN1_HUMAN
NC score	0.010690 (rank : 23)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	218	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.