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Network neighborhood for query Sequence : OPLA_MOUSE

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OPLA_MOUSE
SwissProt Accessions	Q8K010, Q8R3K2	Gene names	Oplah
Domain Architecture
Description	5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (Pyroglutamase) (5- OPase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

OPLA_HUMAN
θ value	0 (rank : 1)	NC score	0.998751 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	O14841, Q75W65, Q9Y4Q0	Gene names	OPLAH
Domain Architecture	No domain graphic available
Description	5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (Pyroglutamase) (5- OPase).

OPLA_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K010, Q8R3K2	Gene names	Oplah
Domain Architecture
Description	5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (Pyroglutamase) (5- OPase).

ADCK1_HUMAN
θ value	1.81305 (rank : 3)	NC score	0.049217 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q86TW2, Q6PD65	Gene names	ADCK1
Domain Architecture	No domain graphic available
Description	Uncharacterized aarF domain-containing protein kinase 1 precursor (EC 2.7.-.-).

FREM2_HUMAN
θ value	4.03905 (rank : 4)	NC score	0.022013 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SZK8, Q4QQG1, Q5H9N8, Q5T6Q1, Q6N057, Q6ZSB4, Q7Z305, Q7Z341	Gene names	FREM2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog).

FREM3_HUMAN
θ value	4.03905 (rank : 5)	NC score	0.023172 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

HXB3_HUMAN
θ value	5.27518 (rank : 6)	NC score	0.008059 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	559	Shared Neighborhood Hits	3
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

HXB3_MOUSE
θ value	5.27518 (rank : 7)	NC score	0.008176 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	493	Shared Neighborhood Hits	3
SwissProt Accessions	P09026, P10285, Q4PJ06, Q61680	Gene names	Hoxb3, Hox-2.7, Hoxb-3
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2.7) (Homeobox protein MH-23).

NNTM_HUMAN
θ value	5.27518 (rank : 8)	NC score	0.034770 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q13423, Q16796, Q8N3V4	Gene names	NNT
Domain Architecture
Description	NAD(P) transhydrogenase, mitochondrial precursor (EC 1.6.1.2) (Pyridine nucleotide transhydrogenase) (Nicotinamide nucleotide transhydrogenase).

NNTM_MOUSE
θ value	5.27518 (rank : 9)	NC score	0.034763 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q61941, Q9JK70	Gene names	Nnt
Domain Architecture
Description	NAD(P) transhydrogenase, mitochondrial precursor (EC 1.6.1.2) (Pyridine nucleotide transhydrogenase) (Nicotinamide nucleotide transhydrogenase).

FOXN1_MOUSE
θ value	6.88961 (rank : 10)	NC score	0.007466 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	300	Shared Neighborhood Hits	2
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

4ET_MOUSE
θ value	8.99809 (rank : 11)	NC score	0.027161 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EST3, Q9CSS3	Gene names	Eif4enif1, Clast4
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

EP400_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.006413 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	556	Shared Neighborhood Hits	3
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

HRBL_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.010493 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	179	Shared Neighborhood Hits	2
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

INSM1_MOUSE
θ value	8.99809 (rank : 14)	NC score	0.012548 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	678	Shared Neighborhood Hits	4
SwissProt Accessions	Q63ZV0, Q9Z113	Gene names	Insm1, Ia1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

Hits sorted by NC score

OPLA_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K010, Q8R3K2	Gene names	Oplah
Domain Architecture
Description	5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (Pyroglutamase) (5- OPase).

OPLA_HUMAN
NC score	0.998751 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	O14841, Q75W65, Q9Y4Q0	Gene names	OPLAH
Domain Architecture	No domain graphic available
Description	5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (Pyroglutamase) (5- OPase).

ADCK1_HUMAN
NC score	0.049217 (rank : 3)	θ value	1.81305 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q86TW2, Q6PD65	Gene names	ADCK1
Domain Architecture	No domain graphic available
Description	Uncharacterized aarF domain-containing protein kinase 1 precursor (EC 2.7.-.-).

NNTM_HUMAN
NC score	0.034770 (rank : 4)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q13423, Q16796, Q8N3V4	Gene names	NNT
Domain Architecture
Description	NAD(P) transhydrogenase, mitochondrial precursor (EC 1.6.1.2) (Pyridine nucleotide transhydrogenase) (Nicotinamide nucleotide transhydrogenase).

NNTM_MOUSE
NC score	0.034763 (rank : 5)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q61941, Q9JK70	Gene names	Nnt
Domain Architecture
Description	NAD(P) transhydrogenase, mitochondrial precursor (EC 1.6.1.2) (Pyridine nucleotide transhydrogenase) (Nicotinamide nucleotide transhydrogenase).

4ET_MOUSE
NC score	0.027161 (rank : 6)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EST3, Q9CSS3	Gene names	Eif4enif1, Clast4
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

FREM3_HUMAN
NC score	0.023172 (rank : 7)	θ value	4.03905 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

FREM2_HUMAN
NC score	0.022013 (rank : 8)	θ value	4.03905 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SZK8, Q4QQG1, Q5H9N8, Q5T6Q1, Q6N057, Q6ZSB4, Q7Z305, Q7Z341	Gene names	FREM2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog).

INSM1_MOUSE
NC score	0.012548 (rank : 9)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	678	Shared Neighborhood Hits	4
SwissProt Accessions	Q63ZV0, Q9Z113	Gene names	Insm1, Ia1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

HRBL_HUMAN
NC score	0.010493 (rank : 10)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	179	Shared Neighborhood Hits	2
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

HXB3_MOUSE
NC score	0.008176 (rank : 11)	θ value	5.27518 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	493	Shared Neighborhood Hits	3
SwissProt Accessions	P09026, P10285, Q4PJ06, Q61680	Gene names	Hoxb3, Hox-2.7, Hoxb-3
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2.7) (Homeobox protein MH-23).

HXB3_HUMAN
NC score	0.008059 (rank : 12)	θ value	5.27518 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	559	Shared Neighborhood Hits	3
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

FOXN1_MOUSE
NC score	0.007466 (rank : 13)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	300	Shared Neighborhood Hits	2
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

EP400_HUMAN
NC score	0.006413 (rank : 14)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	556	Shared Neighborhood Hits	3
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).