Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : IL2RB_HUMAN

For an explanation of this page, click here

IL2RB_HUMAN
SwissProt Accessions	P14784	Gene names	IL2RB
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (p75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IL2RB_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	54	Target Neighborhood Hits	54	Shared Neighborhood Hits	54
SwissProt Accessions	P14784	Gene names	IL2RB
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (p75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

IL2RB_MOUSE
θ value	5.56804e-159 (rank : 2)	NC score	0.953638 (rank : 2)
Query Neighborhood Hits	54	Target Neighborhood Hits	51	Shared Neighborhood Hits	20
SwissProt Accessions	P16297, Q3TZT2	Gene names	Il2rb
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

IL21R_HUMAN
θ value	4.16044e-13 (rank : 3)	NC score	0.544465 (rank : 5)
Query Neighborhood Hits	54	Target Neighborhood Hits	53	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HBE5, Q96HZ1, Q9HB91	Gene names	IL21R, NILR
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor).

IL9R_HUMAN
θ value	2.0648e-12 (rank : 4)	NC score	0.562443 (rank : 3)
Query Neighborhood Hits	54	Target Neighborhood Hits	35	Shared Neighborhood Hits	17
SwissProt Accessions	Q01113, Q14634, Q8WWU1, Q96TF0	Gene names	IL9R
Domain Architecture	No domain graphic available
Description	Interleukin-9 receptor precursor (IL-9R) (CD129 antigen).

IL9R_MOUSE
θ value	1.02475e-11 (rank : 5)	NC score	0.546278 (rank : 4)
Query Neighborhood Hits	54	Target Neighborhood Hits	38	Shared Neighborhood Hits	18
SwissProt Accessions	Q01114	Gene names	Il9r
Domain Architecture	No domain graphic available
Description	Interleukin-9 receptor precursor (IL-9R) (CD129 antigen).

IL21R_MOUSE
θ value	8.67504e-11 (rank : 6)	NC score	0.517347 (rank : 6)
Query Neighborhood Hits	54	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JHX3, Q9ESM1	Gene names	Il21r, Nilr
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor) (Lymphocyte receptor beta) (LR-beta) (Novel cytokine receptor NR8).

IL3RB_MOUSE
θ value	4.1701e-05 (rank : 7)	NC score	0.276516 (rank : 9)
Query Neighborhood Hits	54	Target Neighborhood Hits	355	Shared Neighborhood Hits	25
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

EPOR_MOUSE
θ value	0.00020696 (rank : 8)	NC score	0.302477 (rank : 8)
Query Neighborhood Hits	54	Target Neighborhood Hits	52	Shared Neighborhood Hits	21
SwissProt Accessions	P14753, Q63852	Gene names	Epor
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

IL2RG_HUMAN
θ value	0.00175202 (rank : 9)	NC score	0.250421 (rank : 12)
Query Neighborhood Hits	54	Target Neighborhood Hits	34	Shared Neighborhood Hits	17
SwissProt Accessions	P31785	Gene names	IL2RG
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

EPOR_HUMAN
θ value	0.00390308 (rank : 10)	NC score	0.308720 (rank : 7)
Query Neighborhood Hits	54	Target Neighborhood Hits	58	Shared Neighborhood Hits	24
SwissProt Accessions	P19235, Q15443	Gene names	EPOR
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

IL3B2_MOUSE
θ value	0.00509761 (rank : 11)	NC score	0.263249 (rank : 11)
Query Neighborhood Hits	54	Target Neighborhood Hits	372	Shared Neighborhood Hits	23
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

IL2RG_MOUSE
θ value	0.0252991 (rank : 12)	NC score	0.212651 (rank : 14)
Query Neighborhood Hits	54	Target Neighborhood Hits	42	Shared Neighborhood Hits	18
SwissProt Accessions	P34902	Gene names	Il2rg
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

LEPR_MOUSE
θ value	0.0330416 (rank : 13)	NC score	0.192922 (rank : 15)
Query Neighborhood Hits	54	Target Neighborhood Hits	109	Shared Neighborhood Hits	28
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

CRLF2_HUMAN
θ value	0.0563607 (rank : 14)	NC score	0.217956 (rank : 13)
Query Neighborhood Hits	54	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HC73, Q9H5R3	Gene names	CRLF2, ILXR
Domain Architecture	No domain graphic available
Description	Cytokine receptor-like factor 2 precursor (Cytokine receptor-like 2) (CRL2) (IL-XR) (Thymic stromal lymphopoietin protein receptor) (TSLPR).

IL6RB_MOUSE
θ value	0.0736092 (rank : 15)	NC score	0.128919 (rank : 20)
Query Neighborhood Hits	54	Target Neighborhood Hits	168	Shared Neighborhood Hits	29
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

PTPRJ_MOUSE
θ value	0.21417 (rank : 16)	NC score	0.028228 (rank : 45)
Query Neighborhood Hits	54	Target Neighborhood Hits	188	Shared Neighborhood Hits	13
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

IL3RB_HUMAN
θ value	0.279714 (rank : 17)	NC score	0.265170 (rank : 10)
Query Neighborhood Hits	54	Target Neighborhood Hits	163	Shared Neighborhood Hits	24
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

LEPR_HUMAN
θ value	0.47712 (rank : 18)	NC score	0.181761 (rank : 16)
Query Neighborhood Hits	54	Target Neighborhood Hits	112	Shared Neighborhood Hits	30
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

FAN_MOUSE
θ value	0.62314 (rank : 19)	NC score	0.029162 (rank : 44)
Query Neighborhood Hits	54	Target Neighborhood Hits	292	Shared Neighborhood Hits	3
SwissProt Accessions	O35242	Gene names	Nsmaf, Fan
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

I13R1_HUMAN
θ value	0.62314 (rank : 20)	NC score	0.110875 (rank : 23)
Query Neighborhood Hits	54	Target Neighborhood Hits	31	Shared Neighborhood Hits	14
SwissProt Accessions	P78552, O95646, Q99656	Gene names	IL13RA1, IL13R, IL13RA
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (CD213a1 antigen).

EPHA6_HUMAN
θ value	0.813845 (rank : 21)	NC score	0.021474 (rank : 52)
Query Neighborhood Hits	54	Target Neighborhood Hits	959	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

TARSH_HUMAN
θ value	0.813845 (rank : 22)	NC score	0.043852 (rank : 42)
Query Neighborhood Hits	54	Target Neighborhood Hits	768	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TPOR_HUMAN
θ value	0.813845 (rank : 23)	NC score	0.122684 (rank : 21)
Query Neighborhood Hits	54	Target Neighborhood Hits	70	Shared Neighborhood Hits	17
SwissProt Accessions	P40238	Gene names	MPL, TPOR
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

EPHB6_HUMAN
θ value	1.06291 (rank : 24)	NC score	0.022506 (rank : 50)
Query Neighborhood Hits	54	Target Neighborhood Hits	912	Shared Neighborhood Hits	20
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

FAN_HUMAN
θ value	1.06291 (rank : 25)	NC score	0.026933 (rank : 46)
Query Neighborhood Hits	54	Target Neighborhood Hits	295	Shared Neighborhood Hits	3
SwissProt Accessions	Q92636	Gene names	NSMAF, FAN
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

CSF1_MOUSE
θ value	1.38821 (rank : 26)	NC score	0.040108 (rank : 43)
Query Neighborhood Hits	54	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	P07141, Q8R3C8	Gene names	Csf1, Csfm
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF).

LIFR_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.087349 (rank : 32)
Query Neighborhood Hits	54	Target Neighborhood Hits	130	Shared Neighborhood Hits	26
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

PASK_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.006627 (rank : 68)
Query Neighborhood Hits	54	Target Neighborhood Hits	857	Shared Neighborhood Hits	9
SwissProt Accessions	Q96RG2, Q86XH6, Q99763, Q9UFR7	Gene names	PASK, KIAA0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN) (hPASK).

PTPRS_HUMAN
θ value	1.81305 (rank : 29)	NC score	0.022015 (rank : 51)
Query Neighborhood Hits	54	Target Neighborhood Hits	472	Shared Neighborhood Hits	23
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

CSF3R_HUMAN
θ value	2.36792 (rank : 30)	NC score	0.073424 (rank : 36)
Query Neighborhood Hits	54	Target Neighborhood Hits	140	Shared Neighborhood Hits	16
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

I12R2_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.096640 (rank : 29)
Query Neighborhood Hits	54	Target Neighborhood Hits	163	Shared Neighborhood Hits	26
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

ANK2_HUMAN
θ value	3.0926 (rank : 32)	NC score	0.005995 (rank : 69)
Query Neighborhood Hits	54	Target Neighborhood Hits	1615	Shared Neighborhood Hits	9
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

COCA1_MOUSE
θ value	3.0926 (rank : 33)	NC score	0.022739 (rank : 49)
Query Neighborhood Hits	54	Target Neighborhood Hits	467	Shared Neighborhood Hits	26
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

EPHA3_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.019047 (rank : 56)
Query Neighborhood Hits	54	Target Neighborhood Hits	1005	Shared Neighborhood Hits	24
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

EPHB6_MOUSE
θ value	3.0926 (rank : 35)	NC score	0.020965 (rank : 53)
Query Neighborhood Hits	54	Target Neighborhood Hits	906	Shared Neighborhood Hits	18
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

I12R2_MOUSE
θ value	3.0926 (rank : 36)	NC score	0.089532 (rank : 31)
Query Neighborhood Hits	54	Target Neighborhood Hits	143	Shared Neighborhood Hits	26
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

CAND1_HUMAN
θ value	4.03905 (rank : 37)	NC score	0.026766 (rank : 48)
Query Neighborhood Hits	54	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q86VP6, O94918, Q6PIY4, Q8NDJ4, Q96JZ9, Q96T19, Q9BTC4, Q9H0G2, Q9P0H7, Q9UF85	Gene names	CAND1, KIAA0829, TIP120, TIP120A
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1) (TBP-interacting protein TIP120A) (TBP-interacting protein of 120 kDa A).

CAND1_MOUSE
θ value	4.03905 (rank : 38)	NC score	0.026804 (rank : 47)
Query Neighborhood Hits	54	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZQ38, Q6PFR0, Q9CV45	Gene names	Cand1, D10Ertd516e, Kiaa0829
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1).

EPHA3_MOUSE
θ value	4.03905 (rank : 39)	NC score	0.020585 (rank : 54)
Query Neighborhood Hits	54	Target Neighborhood Hits	1009	Shared Neighborhood Hits	27
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

I12R1_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.052823 (rank : 41)
Query Neighborhood Hits	54	Target Neighborhood Hits	78	Shared Neighborhood Hits	21
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

IL6RB_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.099424 (rank : 25)
Query Neighborhood Hits	54	Target Neighborhood Hits	181	Shared Neighborhood Hits	30
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

CD45_MOUSE
θ value	5.27518 (rank : 42)	NC score	0.015677 (rank : 61)
Query Neighborhood Hits	54	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

EPHA6_MOUSE
θ value	5.27518 (rank : 43)	NC score	0.019264 (rank : 55)
Query Neighborhood Hits	54	Target Neighborhood Hits	946	Shared Neighborhood Hits	20
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

IF4B_MOUSE
θ value	5.27518 (rank : 44)	NC score	0.016336 (rank : 59)
Query Neighborhood Hits	54	Target Neighborhood Hits	368	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

IRAK2_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.011842 (rank : 63)
Query Neighborhood Hits	54	Target Neighborhood Hits	714	Shared Neighborhood Hits	11
SwissProt Accessions	O43187	Gene names	IRAK2
Domain Architecture
Description	Interleukin-1 receptor-associated kinase-like 2 (IRAK-2).

SAPS1_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.010310 (rank : 65)
Query Neighborhood Hits	54	Target Neighborhood Hits	704	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

CNTN1_HUMAN
θ value	6.88961 (rank : 47)	NC score	0.010819 (rank : 64)
Query Neighborhood Hits	54	Target Neighborhood Hits	431	Shared Neighborhood Hits	14
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

CRLF2_MOUSE
θ value	6.88961 (rank : 48)	NC score	0.150091 (rank : 17)
Query Neighborhood Hits	54	Target Neighborhood Hits	39	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CII9, Q9CRJ6, Q9JIE7, Q9JIQ7, Q9JJH8, Q9JMD5	Gene names	Crlf2, Crlm2, Tpte2, Tslpr
Domain Architecture
Description	Cytokine receptor-like factor 2 precursor (Type I cytokine receptor delta 1) (Cytokine receptor-like molecule 2) (CRLM-2) (Thymic stromal lymphopoietin protein receptor) (TSLPR).

MOCOS_MOUSE
θ value	6.88961 (rank : 49)	NC score	0.017642 (rank : 58)
Query Neighborhood Hits	54	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q14CH1	Gene names	Mocos
Domain Architecture	No domain graphic available
Description	Molybdenum cofactor sulfurase (EC 4.4.-.-) (MoCo sulfurase) (MOS).

EPHA5_HUMAN
θ value	8.99809 (rank : 50)	NC score	0.018017 (rank : 57)
Query Neighborhood Hits	54	Target Neighborhood Hits	1009	Shared Neighborhood Hits	24
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

EPHA5_MOUSE
θ value	8.99809 (rank : 51)	NC score	0.015993 (rank : 60)
Query Neighborhood Hits	54	Target Neighborhood Hits	950	Shared Neighborhood Hits	24
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

JHD3B_HUMAN
θ value	8.99809 (rank : 52)	NC score	0.006739 (rank : 67)
Query Neighborhood Hits	54	Target Neighborhood Hits	128	Shared Neighborhood Hits	3
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

NRX2A_HUMAN
θ value	8.99809 (rank : 53)	NC score	0.008518 (rank : 66)
Query Neighborhood Hits	54	Target Neighborhood Hits	614	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	8.99809 (rank : 54)	NC score	0.012501 (rank : 62)
Query Neighborhood Hits	54	Target Neighborhood Hits	481	Shared Neighborhood Hits	6
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

CRLF1_HUMAN
θ value	θ > 10 (rank : 55)	NC score	0.098435 (rank : 26)
Query Neighborhood Hits	54	Target Neighborhood Hits	122	Shared Neighborhood Hits	32
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

CRLF1_MOUSE
θ value	θ > 10 (rank : 56)	NC score	0.097672 (rank : 28)
Query Neighborhood Hits	54	Target Neighborhood Hits	116	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

CSF3R_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.071019 (rank : 37)
Query Neighborhood Hits	54	Target Neighborhood Hits	104	Shared Neighborhood Hits	12
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

I13R1_MOUSE
θ value	θ > 10 (rank : 58)	NC score	0.105640 (rank : 24)
Query Neighborhood Hits	54	Target Neighborhood Hits	48	Shared Neighborhood Hits	17
SwissProt Accessions	O09030, Q7TT27	Gene names	Il13ra1, Il13r, Il13ra
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (Interleukin-13-binding protein) (NR4) (CD213a1 antigen).

I13R2_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.098401 (rank : 27)
Query Neighborhood Hits	54	Target Neighborhood Hits	41	Shared Neighborhood Hits	17
SwissProt Accessions	Q14627, O00667	Gene names	IL13RA2, IL13R
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-2 chain precursor (Interleukin-13- binding protein) (CD213a2 antigen).

I27RA_MOUSE
θ value	θ > 10 (rank : 60)	NC score	0.063293 (rank : 38)
Query Neighborhood Hits	54	Target Neighborhood Hits	55	Shared Neighborhood Hits	16
SwissProt Accessions	O70394	Gene names	Il27ra, Tccr, Wsx1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR).

IL4RA_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.085903 (rank : 33)
Query Neighborhood Hits	54	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

IL4RA_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.119864 (rank : 22)
Query Neighborhood Hits	54	Target Neighborhood Hits	194	Shared Neighborhood Hits	16
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

IL5RA_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.135155 (rank : 18)
Query Neighborhood Hits	54	Target Neighborhood Hits	44	Shared Neighborhood Hits	16
SwissProt Accessions	Q01344, Q6ISX9	Gene names	IL5RA, IL5R
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen) (CDw125).

IL5RA_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.084917 (rank : 34)
Query Neighborhood Hits	54	Target Neighborhood Hits	33	Shared Neighborhood Hits	13
SwissProt Accessions	P21183	Gene names	Il5ra, Il5r
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen).

IL7RA_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.132347 (rank : 19)
Query Neighborhood Hits	54	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	P16871, Q6SV45, Q9UPC1	Gene names	IL7R
Domain Architecture
Description	Interleukin-7 receptor alpha chain precursor (IL-7R-alpha) (CD127 antigen) (CDw127).

IL7RA_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.083835 (rank : 35)
Query Neighborhood Hits	54	Target Neighborhood Hits	34	Shared Neighborhood Hits	15
SwissProt Accessions	P16872	Gene names	Il7r
Domain Architecture
Description	Interleukin-7 receptor alpha chain precursor (IL-7R-alpha) (CD127 antigen).

LIFR_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.060647 (rank : 39)
Query Neighborhood Hits	54	Target Neighborhood Hits	127	Shared Neighborhood Hits	16
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

PRLR_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.053328 (rank : 40)
Query Neighborhood Hits	54	Target Neighborhood Hits	82	Shared Neighborhood Hits	16
SwissProt Accessions	Q08501, P15212, P15213, Q62099	Gene names	Prlr
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

TPOR_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.093713 (rank : 30)
Query Neighborhood Hits	54	Target Neighborhood Hits	56	Shared Neighborhood Hits	17
SwissProt Accessions	Q08351	Gene names	Mpl, Tpor
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

Hits sorted by NC score

IL2RB_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	54	Target Neighborhood Hits	54	Shared Neighborhood Hits	54
SwissProt Accessions	P14784	Gene names	IL2RB
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (p75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

IL2RB_MOUSE
NC score	0.953638 (rank : 2)	θ value	5.56804e-159 (rank : 2)
Query Neighborhood Hits	54	Target Neighborhood Hits	51	Shared Neighborhood Hits	20
SwissProt Accessions	P16297, Q3TZT2	Gene names	Il2rb
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

IL9R_HUMAN
NC score	0.562443 (rank : 3)	θ value	2.0648e-12 (rank : 4)
Query Neighborhood Hits	54	Target Neighborhood Hits	35	Shared Neighborhood Hits	17
SwissProt Accessions	Q01113, Q14634, Q8WWU1, Q96TF0	Gene names	IL9R
Domain Architecture	No domain graphic available
Description	Interleukin-9 receptor precursor (IL-9R) (CD129 antigen).

IL9R_MOUSE
NC score	0.546278 (rank : 4)	θ value	1.02475e-11 (rank : 5)
Query Neighborhood Hits	54	Target Neighborhood Hits	38	Shared Neighborhood Hits	18
SwissProt Accessions	Q01114	Gene names	Il9r
Domain Architecture	No domain graphic available
Description	Interleukin-9 receptor precursor (IL-9R) (CD129 antigen).

IL21R_HUMAN
NC score	0.544465 (rank : 5)	θ value	4.16044e-13 (rank : 3)
Query Neighborhood Hits	54	Target Neighborhood Hits	53	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HBE5, Q96HZ1, Q9HB91	Gene names	IL21R, NILR
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor).

IL21R_MOUSE
NC score	0.517347 (rank : 6)	θ value	8.67504e-11 (rank : 6)
Query Neighborhood Hits	54	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JHX3, Q9ESM1	Gene names	Il21r, Nilr
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor) (Lymphocyte receptor beta) (LR-beta) (Novel cytokine receptor NR8).

EPOR_HUMAN
NC score	0.308720 (rank : 7)	θ value	0.00390308 (rank : 10)
Query Neighborhood Hits	54	Target Neighborhood Hits	58	Shared Neighborhood Hits	24
SwissProt Accessions	P19235, Q15443	Gene names	EPOR
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

EPOR_MOUSE
NC score	0.302477 (rank : 8)	θ value	0.00020696 (rank : 8)
Query Neighborhood Hits	54	Target Neighborhood Hits	52	Shared Neighborhood Hits	21
SwissProt Accessions	P14753, Q63852	Gene names	Epor
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

IL3RB_MOUSE
NC score	0.276516 (rank : 9)	θ value	4.1701e-05 (rank : 7)
Query Neighborhood Hits	54	Target Neighborhood Hits	355	Shared Neighborhood Hits	25
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

IL3RB_HUMAN
NC score	0.265170 (rank : 10)	θ value	0.279714 (rank : 17)
Query Neighborhood Hits	54	Target Neighborhood Hits	163	Shared Neighborhood Hits	24
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

IL3B2_MOUSE
NC score	0.263249 (rank : 11)	θ value	0.00509761 (rank : 11)
Query Neighborhood Hits	54	Target Neighborhood Hits	372	Shared Neighborhood Hits	23
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

IL2RG_HUMAN
NC score	0.250421 (rank : 12)	θ value	0.00175202 (rank : 9)
Query Neighborhood Hits	54	Target Neighborhood Hits	34	Shared Neighborhood Hits	17
SwissProt Accessions	P31785	Gene names	IL2RG
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

CRLF2_HUMAN
NC score	0.217956 (rank : 13)	θ value	0.0563607 (rank : 14)
Query Neighborhood Hits	54	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HC73, Q9H5R3	Gene names	CRLF2, ILXR
Domain Architecture	No domain graphic available
Description	Cytokine receptor-like factor 2 precursor (Cytokine receptor-like 2) (CRL2) (IL-XR) (Thymic stromal lymphopoietin protein receptor) (TSLPR).

IL2RG_MOUSE
NC score	0.212651 (rank : 14)	θ value	0.0252991 (rank : 12)
Query Neighborhood Hits	54	Target Neighborhood Hits	42	Shared Neighborhood Hits	18
SwissProt Accessions	P34902	Gene names	Il2rg
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

LEPR_MOUSE
NC score	0.192922 (rank : 15)	θ value	0.0330416 (rank : 13)
Query Neighborhood Hits	54	Target Neighborhood Hits	109	Shared Neighborhood Hits	28
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

LEPR_HUMAN
NC score	0.181761 (rank : 16)	θ value	0.47712 (rank : 18)
Query Neighborhood Hits	54	Target Neighborhood Hits	112	Shared Neighborhood Hits	30
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

CRLF2_MOUSE
NC score	0.150091 (rank : 17)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	54	Target Neighborhood Hits	39	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CII9, Q9CRJ6, Q9JIE7, Q9JIQ7, Q9JJH8, Q9JMD5	Gene names	Crlf2, Crlm2, Tpte2, Tslpr
Domain Architecture
Description	Cytokine receptor-like factor 2 precursor (Type I cytokine receptor delta 1) (Cytokine receptor-like molecule 2) (CRLM-2) (Thymic stromal lymphopoietin protein receptor) (TSLPR).

IL5RA_HUMAN
NC score	0.135155 (rank : 18)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	54	Target Neighborhood Hits	44	Shared Neighborhood Hits	16
SwissProt Accessions	Q01344, Q6ISX9	Gene names	IL5RA, IL5R
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen) (CDw125).

IL7RA_HUMAN
NC score	0.132347 (rank : 19)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	54	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	P16871, Q6SV45, Q9UPC1	Gene names	IL7R
Domain Architecture
Description	Interleukin-7 receptor alpha chain precursor (IL-7R-alpha) (CD127 antigen) (CDw127).

IL6RB_MOUSE
NC score	0.128919 (rank : 20)	θ value	0.0736092 (rank : 15)
Query Neighborhood Hits	54	Target Neighborhood Hits	168	Shared Neighborhood Hits	29
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

TPOR_HUMAN
NC score	0.122684 (rank : 21)	θ value	0.813845 (rank : 23)
Query Neighborhood Hits	54	Target Neighborhood Hits	70	Shared Neighborhood Hits	17
SwissProt Accessions	P40238	Gene names	MPL, TPOR
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

IL4RA_MOUSE
NC score	0.119864 (rank : 22)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	54	Target Neighborhood Hits	194	Shared Neighborhood Hits	16
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

I13R1_HUMAN
NC score	0.110875 (rank : 23)	θ value	0.62314 (rank : 20)
Query Neighborhood Hits	54	Target Neighborhood Hits	31	Shared Neighborhood Hits	14
SwissProt Accessions	P78552, O95646, Q99656	Gene names	IL13RA1, IL13R, IL13RA
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (CD213a1 antigen).

I13R1_MOUSE
NC score	0.105640 (rank : 24)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	54	Target Neighborhood Hits	48	Shared Neighborhood Hits	17
SwissProt Accessions	O09030, Q7TT27	Gene names	Il13ra1, Il13r, Il13ra
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (Interleukin-13-binding protein) (NR4) (CD213a1 antigen).

IL6RB_HUMAN
NC score	0.099424 (rank : 25)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	54	Target Neighborhood Hits	181	Shared Neighborhood Hits	30
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

CRLF1_HUMAN
NC score	0.098435 (rank : 26)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	54	Target Neighborhood Hits	122	Shared Neighborhood Hits	32
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

I13R2_HUMAN
NC score	0.098401 (rank : 27)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	54	Target Neighborhood Hits	41	Shared Neighborhood Hits	17
SwissProt Accessions	Q14627, O00667	Gene names	IL13RA2, IL13R
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-2 chain precursor (Interleukin-13- binding protein) (CD213a2 antigen).

CRLF1_MOUSE
NC score	0.097672 (rank : 28)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	54	Target Neighborhood Hits	116	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

I12R2_HUMAN
NC score	0.096640 (rank : 29)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	54	Target Neighborhood Hits	163	Shared Neighborhood Hits	26
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

TPOR_MOUSE
NC score	0.093713 (rank : 30)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	54	Target Neighborhood Hits	56	Shared Neighborhood Hits	17
SwissProt Accessions	Q08351	Gene names	Mpl, Tpor
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

I12R2_MOUSE
NC score	0.089532 (rank : 31)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	54	Target Neighborhood Hits	143	Shared Neighborhood Hits	26
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

LIFR_HUMAN
NC score	0.087349 (rank : 32)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	54	Target Neighborhood Hits	130	Shared Neighborhood Hits	26
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

IL4RA_HUMAN
NC score	0.085903 (rank : 33)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	54	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

IL5RA_MOUSE
NC score	0.084917 (rank : 34)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	54	Target Neighborhood Hits	33	Shared Neighborhood Hits	13
SwissProt Accessions	P21183	Gene names	Il5ra, Il5r
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen).

IL7RA_MOUSE
NC score	0.083835 (rank : 35)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	54	Target Neighborhood Hits	34	Shared Neighborhood Hits	15
SwissProt Accessions	P16872	Gene names	Il7r
Domain Architecture
Description	Interleukin-7 receptor alpha chain precursor (IL-7R-alpha) (CD127 antigen).

CSF3R_HUMAN
NC score	0.073424 (rank : 36)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	54	Target Neighborhood Hits	140	Shared Neighborhood Hits	16
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

CSF3R_MOUSE
NC score	0.071019 (rank : 37)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	54	Target Neighborhood Hits	104	Shared Neighborhood Hits	12
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

I27RA_MOUSE
NC score	0.063293 (rank : 38)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	54	Target Neighborhood Hits	55	Shared Neighborhood Hits	16
SwissProt Accessions	O70394	Gene names	Il27ra, Tccr, Wsx1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR).

LIFR_MOUSE
NC score	0.060647 (rank : 39)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	54	Target Neighborhood Hits	127	Shared Neighborhood Hits	16
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

PRLR_MOUSE
NC score	0.053328 (rank : 40)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	54	Target Neighborhood Hits	82	Shared Neighborhood Hits	16
SwissProt Accessions	Q08501, P15212, P15213, Q62099	Gene names	Prlr
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

I12R1_HUMAN
NC score	0.052823 (rank : 41)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	54	Target Neighborhood Hits	78	Shared Neighborhood Hits	21
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

TARSH_HUMAN
NC score	0.043852 (rank : 42)	θ value	0.813845 (rank : 22)
Query Neighborhood Hits	54	Target Neighborhood Hits	768	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

CSF1_MOUSE
NC score	0.040108 (rank : 43)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	54	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	P07141, Q8R3C8	Gene names	Csf1, Csfm
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF).

FAN_MOUSE
NC score	0.029162 (rank : 44)	θ value	0.62314 (rank : 19)
Query Neighborhood Hits	54	Target Neighborhood Hits	292	Shared Neighborhood Hits	3
SwissProt Accessions	O35242	Gene names	Nsmaf, Fan
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

PTPRJ_MOUSE
NC score	0.028228 (rank : 45)	θ value	0.21417 (rank : 16)
Query Neighborhood Hits	54	Target Neighborhood Hits	188	Shared Neighborhood Hits	13
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

FAN_HUMAN
NC score	0.026933 (rank : 46)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	54	Target Neighborhood Hits	295	Shared Neighborhood Hits	3
SwissProt Accessions	Q92636	Gene names	NSMAF, FAN
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

CAND1_MOUSE
NC score	0.026804 (rank : 47)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	54	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZQ38, Q6PFR0, Q9CV45	Gene names	Cand1, D10Ertd516e, Kiaa0829
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1).

CAND1_HUMAN
NC score	0.026766 (rank : 48)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	54	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q86VP6, O94918, Q6PIY4, Q8NDJ4, Q96JZ9, Q96T19, Q9BTC4, Q9H0G2, Q9P0H7, Q9UF85	Gene names	CAND1, KIAA0829, TIP120, TIP120A
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1) (TBP-interacting protein TIP120A) (TBP-interacting protein of 120 kDa A).

COCA1_MOUSE
NC score	0.022739 (rank : 49)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	54	Target Neighborhood Hits	467	Shared Neighborhood Hits	26
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

EPHB6_HUMAN
NC score	0.022506 (rank : 50)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	54	Target Neighborhood Hits	912	Shared Neighborhood Hits	20
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

PTPRS_HUMAN
NC score	0.022015 (rank : 51)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	54	Target Neighborhood Hits	472	Shared Neighborhood Hits	23
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

EPHA6_HUMAN
NC score	0.021474 (rank : 52)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	54	Target Neighborhood Hits	959	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHB6_MOUSE
NC score	0.020965 (rank : 53)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	54	Target Neighborhood Hits	906	Shared Neighborhood Hits	18
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

EPHA3_MOUSE
NC score	0.020585 (rank : 54)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	54	Target Neighborhood Hits	1009	Shared Neighborhood Hits	27
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

EPHA6_MOUSE
NC score	0.019264 (rank : 55)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	54	Target Neighborhood Hits	946	Shared Neighborhood Hits	20
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHA3_HUMAN
NC score	0.019047 (rank : 56)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	54	Target Neighborhood Hits	1005	Shared Neighborhood Hits	24
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

EPHA5_HUMAN
NC score	0.018017 (rank : 57)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	54	Target Neighborhood Hits	1009	Shared Neighborhood Hits	24
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

MOCOS_MOUSE
NC score	0.017642 (rank : 58)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	54	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q14CH1	Gene names	Mocos
Domain Architecture	No domain graphic available
Description	Molybdenum cofactor sulfurase (EC 4.4.-.-) (MoCo sulfurase) (MOS).

IF4B_MOUSE
NC score	0.016336 (rank : 59)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	54	Target Neighborhood Hits	368	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

EPHA5_MOUSE
NC score	0.015993 (rank : 60)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	54	Target Neighborhood Hits	950	Shared Neighborhood Hits	24
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

CD45_MOUSE
NC score	0.015677 (rank : 61)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	54	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

NRX2B_HUMAN
NC score	0.012501 (rank : 62)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	54	Target Neighborhood Hits	481	Shared Neighborhood Hits	6
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

IRAK2_HUMAN
NC score	0.011842 (rank : 63)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	54	Target Neighborhood Hits	714	Shared Neighborhood Hits	11
SwissProt Accessions	O43187	Gene names	IRAK2
Domain Architecture
Description	Interleukin-1 receptor-associated kinase-like 2 (IRAK-2).

CNTN1_HUMAN
NC score	0.010819 (rank : 64)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	54	Target Neighborhood Hits	431	Shared Neighborhood Hits	14
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

SAPS1_HUMAN
NC score	0.010310 (rank : 65)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	54	Target Neighborhood Hits	704	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

NRX2A_HUMAN
NC score	0.008518 (rank : 66)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	54	Target Neighborhood Hits	614	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

JHD3B_HUMAN
NC score	0.006739 (rank : 67)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	54	Target Neighborhood Hits	128	Shared Neighborhood Hits	3
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

PASK_HUMAN
NC score	0.006627 (rank : 68)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	54	Target Neighborhood Hits	857	Shared Neighborhood Hits	9
SwissProt Accessions	Q96RG2, Q86XH6, Q99763, Q9UFR7	Gene names	PASK, KIAA0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN) (hPASK).

ANK2_HUMAN
NC score	0.005995 (rank : 69)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	54	Target Neighborhood Hits	1615	Shared Neighborhood Hits	9
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).