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Network neighborhood for query Sequence : I5P1_HUMAN

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I5P1_HUMAN
SwissProt Accessions	Q14642, Q14640	Gene names	INPP5A
Domain Architecture
Description	Type I inositol-1,4,5-trisphosphate 5-phosphatase (EC 3.1.3.56) (5PTase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

I5P1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q14642, Q14640	Gene names	INPP5A
Domain Architecture
Description	Type I inositol-1,4,5-trisphosphate 5-phosphatase (EC 3.1.3.56) (5PTase).

OCRL_HUMAN
θ value	7.1131e-05 (rank : 2)	NC score	0.246273 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	77	Shared Neighborhood Hits	12
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

INP5E_HUMAN
θ value	0.0113563 (rank : 3)	NC score	0.223674 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	201	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

I5P2_HUMAN
θ value	0.0961366 (rank : 4)	NC score	0.207708 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	86	Shared Neighborhood Hits	12
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

SYNJ2_HUMAN
θ value	0.47712 (rank : 5)	NC score	0.178876 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	136	Shared Neighborhood Hits	12
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

INP5E_MOUSE
θ value	0.62314 (rank : 6)	NC score	0.206197 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	59	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JII1, Q3TCC9	Gene names	Inpp5e
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

DLX4_HUMAN
θ value	0.813845 (rank : 7)	NC score	0.022193 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	350	Shared Neighborhood Hits	2
SwissProt Accessions	Q92988, O60480, Q13265, Q6PJK0, Q9HBE0	Gene names	DLX4, BP1, DLX7, DLX8
Domain Architecture	No domain graphic available
Description	Homeobox protein DLX-4 (DLX-7) (DLX-8) (Beta protein 1).

SYNJ1_MOUSE
θ value	1.06291 (rank : 8)	NC score	0.159122 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	516	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYNJ2_MOUSE
θ value	1.06291 (rank : 9)	NC score	0.176391 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	87	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D2G5, O35404, O88399, O88400, O88401, O88402, O88403, O88404	Gene names	Synj2, Kiaa0348
Domain Architecture
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

SKIP_MOUSE
θ value	1.38821 (rank : 10)	NC score	0.175835 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C5L6, O09040	Gene names	Skip, Pps
Domain Architecture
Description	Skeletal muscle and kidney-enriched inositol phosphatase (EC 3.1.3.56).

SYNJ1_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.157933 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	498	Shared Neighborhood Hits	12
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SKIP_HUMAN
θ value	2.36792 (rank : 12)	NC score	0.172496 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BT40, Q15733, Q9NPJ5, Q9P2R5	Gene names	SKIP, PPS
Domain Architecture
Description	Skeletal muscle and kidney-enriched inositol phosphatase (EC 3.1.3.56).

PI5PA_MOUSE
θ value	4.03905 (rank : 13)	NC score	0.147989 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	331	Shared Neighborhood Hits	12
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

BPTF_HUMAN
θ value	5.27518 (rank : 14)	NC score	0.017240 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	786	Shared Neighborhood Hits	2
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

DIAP2_MOUSE
θ value	8.99809 (rank : 15)	NC score	0.010922 (rank : 16)
Query Neighborhood Hits	15	Target Neighborhood Hits	260	Shared Neighborhood Hits	2
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

PI5PA_HUMAN
θ value	θ > 10 (rank : 16)	NC score	0.123290 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	749	Shared Neighborhood Hits	11
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

Hits sorted by NC score

I5P1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q14642, Q14640	Gene names	INPP5A
Domain Architecture
Description	Type I inositol-1,4,5-trisphosphate 5-phosphatase (EC 3.1.3.56) (5PTase).

OCRL_HUMAN
NC score	0.246273 (rank : 2)	θ value	7.1131e-05 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	77	Shared Neighborhood Hits	12
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

INP5E_HUMAN
NC score	0.223674 (rank : 3)	θ value	0.0113563 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	201	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

I5P2_HUMAN
NC score	0.207708 (rank : 4)	θ value	0.0961366 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	86	Shared Neighborhood Hits	12
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

INP5E_MOUSE
NC score	0.206197 (rank : 5)	θ value	0.62314 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	59	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JII1, Q3TCC9	Gene names	Inpp5e
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

SYNJ2_HUMAN
NC score	0.178876 (rank : 6)	θ value	0.47712 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	136	Shared Neighborhood Hits	12
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

SYNJ2_MOUSE
NC score	0.176391 (rank : 7)	θ value	1.06291 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	87	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D2G5, O35404, O88399, O88400, O88401, O88402, O88403, O88404	Gene names	Synj2, Kiaa0348
Domain Architecture
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

SKIP_MOUSE
NC score	0.175835 (rank : 8)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C5L6, O09040	Gene names	Skip, Pps
Domain Architecture
Description	Skeletal muscle and kidney-enriched inositol phosphatase (EC 3.1.3.56).

SKIP_HUMAN
NC score	0.172496 (rank : 9)	θ value	2.36792 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BT40, Q15733, Q9NPJ5, Q9P2R5	Gene names	SKIP, PPS
Domain Architecture
Description	Skeletal muscle and kidney-enriched inositol phosphatase (EC 3.1.3.56).

SYNJ1_MOUSE
NC score	0.159122 (rank : 10)	θ value	1.06291 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	516	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYNJ1_HUMAN
NC score	0.157933 (rank : 11)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	498	Shared Neighborhood Hits	12
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

PI5PA_MOUSE
NC score	0.147989 (rank : 12)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	331	Shared Neighborhood Hits	12
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PI5PA_HUMAN
NC score	0.123290 (rank : 13)	θ value	θ > 10 (rank : 16)
Query Neighborhood Hits	15	Target Neighborhood Hits	749	Shared Neighborhood Hits	11
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

DLX4_HUMAN
NC score	0.022193 (rank : 14)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	350	Shared Neighborhood Hits	2
SwissProt Accessions	Q92988, O60480, Q13265, Q6PJK0, Q9HBE0	Gene names	DLX4, BP1, DLX7, DLX8
Domain Architecture	No domain graphic available
Description	Homeobox protein DLX-4 (DLX-7) (DLX-8) (Beta protein 1).

BPTF_HUMAN
NC score	0.017240 (rank : 15)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	786	Shared Neighborhood Hits	2
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

DIAP2_MOUSE
NC score	0.010922 (rank : 16)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	260	Shared Neighborhood Hits	2
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).