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Network neighborhood for query Sequence : I2C4_HUMAN

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I2C4_HUMAN
SwissProt Accessions	Q9HCK5	Gene names	EIF2C4, AGO4, KIAA1567
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 4 (eIF2C 4) (eIF-2C 4) (Argonaute-4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

I2C1_HUMAN
θ value	0 (rank : 1)	NC score	0.998854 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UL18, Q5TA57, Q6P4S0	Gene names	EIF2C1, AGO1
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 1 (eIF2C 1) (eIF-2C 1) (Argonaute-1) (Putative RNA-binding protein Q99).

I2C1_MOUSE
θ value	0 (rank : 2)	NC score	0.998907 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CJG1	Gene names	Eif2c1, Ago1
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 1 (eIF2C 1) (eIF-2C 1) (Argonaute-1) (Piwi/argonaute family protein meIF2C1).

I2C2_HUMAN
θ value	0 (rank : 3)	NC score	0.998544 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	23	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UKV8, Q8TCZ5, Q8WV58, Q96ID1	Gene names	EIF2C2, AGO2
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 2 (eIF2C 2) (eIF-2C 2) (Argonaute-2) (Slicer protein) (PAZ Piwi domain protein) (PPD).

I2C2_MOUSE
θ value	0 (rank : 4)	NC score	0.998365 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	27	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CJG0, Q4VAB3, Q571J6	Gene names	Eif2c2, Ago2, Kiaa4215
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 2 (eIF2C 2) (eIF-2C 2) (Argonaute-2) (Slicer protein) (Piwi/argonaute family protein meIF2C2).

I2C3_HUMAN
θ value	0 (rank : 5)	NC score	0.998958 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	21	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H9G7, Q5TA55, Q9H1U6	Gene names	EIF2C3, AGO3
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 3 (eIF2C 3) (eIF-2C 3) (Argonaute-3).

I2C3_MOUSE
θ value	0 (rank : 6)	NC score	0.998568 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CJF9	Gene names	Eif2c3, Ago3
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 3 (eIF2C 3) (eIF-2C 3) (Argonaute-3) (Piwi/argonaute family protein meIF2C3).

I2C4_HUMAN
θ value	0 (rank : 7)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HCK5	Gene names	EIF2C4, AGO4, KIAA1567
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 4 (eIF2C 4) (eIF-2C 4) (Argonaute-4).

I2C4_MOUSE
θ value	0 (rank : 8)	NC score	0.999856 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	21	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CJF8	Gene names	Eif2c4, Ago4
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 4 (eIF2C 4) (eIF-2C 4) (Argonaute-4) (Piwi/argonaute family protein meIF2C4).

PIWL1_HUMAN
θ value	1.6774e-38 (rank : 9)	NC score	0.751705 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	31	Shared Neighborhood Hits	15
SwissProt Accessions	Q96J94, O95404, Q8NA60, Q8TBY5, Q96JD5	Gene names	PIWIL1, HIWI
Domain Architecture	No domain graphic available
Description	Piwi-like protein 1.

PIWL1_MOUSE
θ value	2.42216e-37 (rank : 10)	NC score	0.747865 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	29	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JMB7	Gene names	Piwil1, Miwi
Domain Architecture	No domain graphic available
Description	Piwi-like protein 1.

PIWL4_HUMAN
θ value	9.20422e-37 (rank : 11)	NC score	0.758050 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z3Z4, Q68CZ4, Q8N8G9, Q8N9V8, Q8NEH2	Gene names	PIWIL4, HILI2, PIWI
Domain Architecture	No domain graphic available
Description	Piwi-like protein 4.

PIWL2_HUMAN
θ value	5.584e-34 (rank : 12)	NC score	0.745118 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	31	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TC59, Q96SW6, Q9NW28	Gene names	PIWIL2, HILI
Domain Architecture	No domain graphic available
Description	Piwi-like protein 2.

PIWL2_MOUSE
θ value	6.17384e-33 (rank : 13)	NC score	0.736794 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	28	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CDG1, Q3TQE8, Q99MV6, Q9JMB6	Gene names	Piwil2, Mili
Domain Architecture	No domain graphic available
Description	Piwi-like protein 2.

PIWL3_HUMAN
θ value	1.98606e-31 (rank : 14)	NC score	0.750422 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	31	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z3Z3	Gene names	PIWIL3
Domain Architecture	No domain graphic available
Description	Piwi-like protein 3.

PIWL4_MOUSE
θ value	2.87452e-22 (rank : 15)	NC score	0.705011 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	34	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CGT6, Q8CC75	Gene names	Piwil4, Miwi2
Domain Architecture	No domain graphic available
Description	Piwi-like protein 4 (mAgo5).

LATS2_HUMAN
θ value	0.21417 (rank : 16)	NC score	0.008462 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	884	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).

LATS2_MOUSE
θ value	0.21417 (rank : 17)	NC score	0.008148 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	879	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TSJ6, Q8CDJ4, Q9JMI3	Gene names	Lats2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein).

UBP22_HUMAN
θ value	3.0926 (rank : 18)	NC score	0.007185 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

SKIL_HUMAN
θ value	4.03905 (rank : 19)	NC score	0.007762 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	460	Shared Neighborhood Hits	3
SwissProt Accessions	P12757, O00464, P12756, Q07501	Gene names	SKIL, SNO
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

SKIL_MOUSE
θ value	6.88961 (rank : 20)	NC score	0.005242 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	719	Shared Neighborhood Hits	4
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

USH1C_MOUSE
θ value	6.88961 (rank : 21)	NC score	0.004991 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	557	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

RAVR1_HUMAN
θ value	8.99809 (rank : 22)	NC score	0.006063 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	159	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IY67, Q8IY60, Q8TF24	Gene names	RAVER1, KIAA1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

Hits sorted by NC score

I2C4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HCK5	Gene names	EIF2C4, AGO4, KIAA1567
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 4 (eIF2C 4) (eIF-2C 4) (Argonaute-4).

I2C4_MOUSE
NC score	0.999856 (rank : 2)	θ value	0 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	21	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CJF8	Gene names	Eif2c4, Ago4
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 4 (eIF2C 4) (eIF-2C 4) (Argonaute-4) (Piwi/argonaute family protein meIF2C4).

I2C3_HUMAN
NC score	0.998958 (rank : 3)	θ value	0 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	21	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H9G7, Q5TA55, Q9H1U6	Gene names	EIF2C3, AGO3
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 3 (eIF2C 3) (eIF-2C 3) (Argonaute-3).

I2C1_MOUSE
NC score	0.998907 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CJG1	Gene names	Eif2c1, Ago1
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 1 (eIF2C 1) (eIF-2C 1) (Argonaute-1) (Piwi/argonaute family protein meIF2C1).

I2C1_HUMAN
NC score	0.998854 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UL18, Q5TA57, Q6P4S0	Gene names	EIF2C1, AGO1
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 1 (eIF2C 1) (eIF-2C 1) (Argonaute-1) (Putative RNA-binding protein Q99).

I2C3_MOUSE
NC score	0.998568 (rank : 6)	θ value	0 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CJF9	Gene names	Eif2c3, Ago3
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 3 (eIF2C 3) (eIF-2C 3) (Argonaute-3) (Piwi/argonaute family protein meIF2C3).

I2C2_HUMAN
NC score	0.998544 (rank : 7)	θ value	0 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	23	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UKV8, Q8TCZ5, Q8WV58, Q96ID1	Gene names	EIF2C2, AGO2
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 2 (eIF2C 2) (eIF-2C 2) (Argonaute-2) (Slicer protein) (PAZ Piwi domain protein) (PPD).

I2C2_MOUSE
NC score	0.998365 (rank : 8)	θ value	0 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	27	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CJG0, Q4VAB3, Q571J6	Gene names	Eif2c2, Ago2, Kiaa4215
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 2 (eIF2C 2) (eIF-2C 2) (Argonaute-2) (Slicer protein) (Piwi/argonaute family protein meIF2C2).

PIWL4_HUMAN
NC score	0.758050 (rank : 9)	θ value	9.20422e-37 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z3Z4, Q68CZ4, Q8N8G9, Q8N9V8, Q8NEH2	Gene names	PIWIL4, HILI2, PIWI
Domain Architecture	No domain graphic available
Description	Piwi-like protein 4.

PIWL1_HUMAN
NC score	0.751705 (rank : 10)	θ value	1.6774e-38 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	31	Shared Neighborhood Hits	15
SwissProt Accessions	Q96J94, O95404, Q8NA60, Q8TBY5, Q96JD5	Gene names	PIWIL1, HIWI
Domain Architecture	No domain graphic available
Description	Piwi-like protein 1.

PIWL3_HUMAN
NC score	0.750422 (rank : 11)	θ value	1.98606e-31 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	31	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z3Z3	Gene names	PIWIL3
Domain Architecture	No domain graphic available
Description	Piwi-like protein 3.

PIWL1_MOUSE
NC score	0.747865 (rank : 12)	θ value	2.42216e-37 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	29	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JMB7	Gene names	Piwil1, Miwi
Domain Architecture	No domain graphic available
Description	Piwi-like protein 1.

PIWL2_HUMAN
NC score	0.745118 (rank : 13)	θ value	5.584e-34 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	31	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TC59, Q96SW6, Q9NW28	Gene names	PIWIL2, HILI
Domain Architecture	No domain graphic available
Description	Piwi-like protein 2.

PIWL2_MOUSE
NC score	0.736794 (rank : 14)	θ value	6.17384e-33 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	28	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CDG1, Q3TQE8, Q99MV6, Q9JMB6	Gene names	Piwil2, Mili
Domain Architecture	No domain graphic available
Description	Piwi-like protein 2.

PIWL4_MOUSE
NC score	0.705011 (rank : 15)	θ value	2.87452e-22 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	34	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CGT6, Q8CC75	Gene names	Piwil4, Miwi2
Domain Architecture	No domain graphic available
Description	Piwi-like protein 4 (mAgo5).

LATS2_HUMAN
NC score	0.008462 (rank : 16)	θ value	0.21417 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	884	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).

LATS2_MOUSE
NC score	0.008148 (rank : 17)	θ value	0.21417 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	879	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TSJ6, Q8CDJ4, Q9JMI3	Gene names	Lats2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein).

SKIL_HUMAN
NC score	0.007762 (rank : 18)	θ value	4.03905 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	460	Shared Neighborhood Hits	3
SwissProt Accessions	P12757, O00464, P12756, Q07501	Gene names	SKIL, SNO
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

UBP22_HUMAN
NC score	0.007185 (rank : 19)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

RAVR1_HUMAN
NC score	0.006063 (rank : 20)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	159	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IY67, Q8IY60, Q8TF24	Gene names	RAVER1, KIAA1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

SKIL_MOUSE
NC score	0.005242 (rank : 21)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	719	Shared Neighborhood Hits	4
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

USH1C_MOUSE
NC score	0.004991 (rank : 22)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	557	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).