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Network neighborhood for query Sequence : HXK3_HUMAN

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HXK3_HUMAN
SwissProt Accessions	P52790	Gene names	HK3
Domain Architecture
Description	Hexokinase-3 (EC 2.7.1.1) (Hexokinase type III) (HK III).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HXK1_HUMAN
θ value	0 (rank : 1)	NC score	0.992291 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P19367, O43443, O43444, O75574, Q5VTC3, Q96HC8, Q9NNZ4, Q9NNZ5	Gene names	HK1
Domain Architecture
Description	Hexokinase-1 (EC 2.7.1.1) (Hexokinase type I) (HK I) (Brain form hexokinase).

HXK1_MOUSE
θ value	0 (rank : 2)	NC score	0.991917 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	P17710, Q61659, Q64476, Q64479	Gene names	Hk1
Domain Architecture
Description	Hexokinase-1 (EC 2.7.1.1) (Hexokinase type I) (HK I) (Hexokinase, tumor isozyme).

HXK2_HUMAN
θ value	0 (rank : 3)	NC score	0.993187 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	P52789, Q8WU87, Q9UN82	Gene names	HK2
Domain Architecture
Description	Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II) (Muscle form hexokinase).

HXK2_MOUSE
θ value	0 (rank : 4)	NC score	0.993053 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O08528	Gene names	Hk2
Domain Architecture
Description	Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II).

HXK3_HUMAN
θ value	0 (rank : 5)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P52790	Gene names	HK3
Domain Architecture
Description	Hexokinase-3 (EC 2.7.1.1) (Hexokinase type III) (HK III).

HXK3_MOUSE
θ value	0 (rank : 6)	NC score	0.999075 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q3TRM8, Q3TAX6, Q3UDP1, Q3UEA4	Gene names	Hk3
Domain Architecture	No domain graphic available
Description	Hexokinase-3 (EC 2.7.1.1) (Hexokinase type III) (HK III).

HXK4_HUMAN
θ value	8.37844e-131 (rank : 7)	NC score	0.976613 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	P35557, Q05810	Gene names	GCK
Domain Architecture
Description	Glucokinase (EC 2.7.1.2) (Hexokinase-4) (Hexokinase type IV) (HK IV) (HK4) (Hexokinase-D).

HXK4_MOUSE
θ value	1.42914e-130 (rank : 8)	NC score	0.976533 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	P52792, P52791	Gene names	Gck, Gk
Domain Architecture
Description	Glucokinase (EC 2.7.1.2) (Hexokinase-4) (Hexokinase type IV) (HK IV) (HK4) (Hexokinase-D).

FAS_HUMAN
θ value	0.365318 (rank : 9)	NC score	0.031100 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	P49327, Q13479, Q16702, Q6P4U5, Q6SS02, Q969R1, Q96C68, Q96IT0	Gene names	FASN, FAS
Domain Architecture
Description	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S- acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S- malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.61); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.10); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)].

CL011_MOUSE
θ value	0.813845 (rank : 10)	NC score	0.031712 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q8QZV7, Q99JT8	Gene names
Domain Architecture	No domain graphic available
Description	Protein C12orf11 homolog.

LAMA3_MOUSE
θ value	2.36792 (rank : 11)	NC score	0.005392 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	859	Shared Neighborhood Hits	3
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

CL011_HUMAN
θ value	3.0926 (rank : 12)	NC score	0.027155 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVM9, Q86WE2, Q96HM2, Q9BTX2, Q9NTB6, Q9NVM5	Gene names	C12orf11
Domain Architecture	No domain graphic available
Description	Protein C12orf11 (Sarcoma antigen NY-SAR-95).

TIMD1_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.008796 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	155	Shared Neighborhood Hits	2
SwissProt Accessions	Q96D42, O43656	Gene names	HAVCR1, TIM1, TIMD1
Domain Architecture	No domain graphic available
Description	Hepatitis A virus cellular receptor 1 precursor (HAVcr-1) (T cell immunoglobulin and mucin domain-containing protein 1) (TIMD-1) (T cell membrane protein 1) (TIM-1) (TIM).

WDR7_MOUSE
θ value	6.88961 (rank : 14)	NC score	0.009141 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	226	Shared Neighborhood Hits	3
SwissProt Accessions	Q920I9, Q80TY3, Q920J0	Gene names	Wdr7, Kiaa0541, Trag
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG).

WDR7_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.008497 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	244	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4E6, Q86UX5, Q86VP2, Q96PS7	Gene names	WDR7, KIAA0541, TRAG
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG) (Rabconnectin-3 beta).

Hits sorted by NC score

HXK3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P52790	Gene names	HK3
Domain Architecture
Description	Hexokinase-3 (EC 2.7.1.1) (Hexokinase type III) (HK III).

HXK3_MOUSE
NC score	0.999075 (rank : 2)	θ value	0 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q3TRM8, Q3TAX6, Q3UDP1, Q3UEA4	Gene names	Hk3
Domain Architecture	No domain graphic available
Description	Hexokinase-3 (EC 2.7.1.1) (Hexokinase type III) (HK III).

HXK2_HUMAN
NC score	0.993187 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	P52789, Q8WU87, Q9UN82	Gene names	HK2
Domain Architecture
Description	Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II) (Muscle form hexokinase).

HXK2_MOUSE
NC score	0.993053 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O08528	Gene names	Hk2
Domain Architecture
Description	Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II).

HXK1_HUMAN
NC score	0.992291 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P19367, O43443, O43444, O75574, Q5VTC3, Q96HC8, Q9NNZ4, Q9NNZ5	Gene names	HK1
Domain Architecture
Description	Hexokinase-1 (EC 2.7.1.1) (Hexokinase type I) (HK I) (Brain form hexokinase).

HXK1_MOUSE
NC score	0.991917 (rank : 6)	θ value	0 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	P17710, Q61659, Q64476, Q64479	Gene names	Hk1
Domain Architecture
Description	Hexokinase-1 (EC 2.7.1.1) (Hexokinase type I) (HK I) (Hexokinase, tumor isozyme).

HXK4_HUMAN
NC score	0.976613 (rank : 7)	θ value	8.37844e-131 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	P35557, Q05810	Gene names	GCK
Domain Architecture
Description	Glucokinase (EC 2.7.1.2) (Hexokinase-4) (Hexokinase type IV) (HK IV) (HK4) (Hexokinase-D).

HXK4_MOUSE
NC score	0.976533 (rank : 8)	θ value	1.42914e-130 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	P52792, P52791	Gene names	Gck, Gk
Domain Architecture
Description	Glucokinase (EC 2.7.1.2) (Hexokinase-4) (Hexokinase type IV) (HK IV) (HK4) (Hexokinase-D).

CL011_MOUSE
NC score	0.031712 (rank : 9)	θ value	0.813845 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q8QZV7, Q99JT8	Gene names
Domain Architecture	No domain graphic available
Description	Protein C12orf11 homolog.

FAS_HUMAN
NC score	0.031100 (rank : 10)	θ value	0.365318 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	P49327, Q13479, Q16702, Q6P4U5, Q6SS02, Q969R1, Q96C68, Q96IT0	Gene names	FASN, FAS
Domain Architecture
Description	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S- acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S- malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.61); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.10); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)].

CL011_HUMAN
NC score	0.027155 (rank : 11)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVM9, Q86WE2, Q96HM2, Q9BTX2, Q9NTB6, Q9NVM5	Gene names	C12orf11
Domain Architecture	No domain graphic available
Description	Protein C12orf11 (Sarcoma antigen NY-SAR-95).

WDR7_MOUSE
NC score	0.009141 (rank : 12)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	226	Shared Neighborhood Hits	3
SwissProt Accessions	Q920I9, Q80TY3, Q920J0	Gene names	Wdr7, Kiaa0541, Trag
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG).

TIMD1_HUMAN
NC score	0.008796 (rank : 13)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	155	Shared Neighborhood Hits	2
SwissProt Accessions	Q96D42, O43656	Gene names	HAVCR1, TIM1, TIMD1
Domain Architecture	No domain graphic available
Description	Hepatitis A virus cellular receptor 1 precursor (HAVcr-1) (T cell immunoglobulin and mucin domain-containing protein 1) (TIMD-1) (T cell membrane protein 1) (TIM-1) (TIM).

WDR7_HUMAN
NC score	0.008497 (rank : 14)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	244	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4E6, Q86UX5, Q86VP2, Q96PS7	Gene names	WDR7, KIAA0541, TRAG
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG) (Rabconnectin-3 beta).

LAMA3_MOUSE
NC score	0.005392 (rank : 15)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	859	Shared Neighborhood Hits	3
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).