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Network neighborhood for query Sequence : HPS3_MOUSE

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HPS3_MOUSE
SwissProt Accessions	Q91VB4, Q8VDX2, Q8VHT1	Gene names	Hps3, Coa
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 3 protein homolog (Cocoa protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HPS3_HUMAN
θ value	0 (rank : 1)	NC score	0.994380 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q969F9, Q8WTV6, Q96AP1, Q96MR3, Q9H608	Gene names	HPS3
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 3 protein.

HPS3_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q91VB4, Q8VDX2, Q8VHT1	Gene names	Hps3, Coa
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 3 protein homolog (Cocoa protein).

CE005_HUMAN
θ value	0.365318 (rank : 3)	NC score	0.030197 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	213	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

UXS1_HUMAN
θ value	1.38821 (rank : 4)	NC score	0.046436 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NBZ7, Q8NBX3, Q9H5C2	Gene names	UXS1
Domain Architecture	No domain graphic available
Description	UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1).

UXS1_MOUSE
θ value	1.38821 (rank : 5)	NC score	0.046444 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q91XL3, Q3U854	Gene names	Uxs1
Domain Architecture	No domain graphic available
Description	UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1).

RFX2_HUMAN
θ value	3.0926 (rank : 6)	NC score	0.036027 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	P48378	Gene names	RFX2
Domain Architecture
Description	DNA-binding protein RFX2.

UROL1_HUMAN
θ value	4.03905 (rank : 7)	NC score	0.017672 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	213	Shared Neighborhood Hits	2
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

LAX1_HUMAN
θ value	5.27518 (rank : 8)	NC score	0.036725 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWV1, Q6NSZ6, Q9NXB4	Gene names	LAX1, LAX
Domain Architecture	No domain graphic available
Description	Lymphocyte transmembrane adapter 1 (Membrane-associated adapter protein LAX) (Linker for activation of X cells).

SMUF1_HUMAN
θ value	5.27518 (rank : 9)	NC score	0.011733 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	135	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF1_MOUSE
θ value	5.27518 (rank : 10)	NC score	0.011638 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	142	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

CEND2_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.010102 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	166	Shared Neighborhood Hits	3
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

AMGO2_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.004752 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	357	Shared Neighborhood Hits	2
SwissProt Accessions	Q86SJ2, Q7Z4A0, Q96CN8	Gene names	AMIGO2, ALI1
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 2 precursor (AMIGO-2) (Alivin-1) (Differentially expressed in gastric adenocarcinomas) (DEGA).

PTN12_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.007030 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
θ value	8.99809 (rank : 14)	NC score	0.007049 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

Hits sorted by NC score

HPS3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q91VB4, Q8VDX2, Q8VHT1	Gene names	Hps3, Coa
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 3 protein homolog (Cocoa protein).

HPS3_HUMAN
NC score	0.994380 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q969F9, Q8WTV6, Q96AP1, Q96MR3, Q9H608	Gene names	HPS3
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 3 protein.

UXS1_MOUSE
NC score	0.046444 (rank : 3)	θ value	1.38821 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q91XL3, Q3U854	Gene names	Uxs1
Domain Architecture	No domain graphic available
Description	UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1).

UXS1_HUMAN
NC score	0.046436 (rank : 4)	θ value	1.38821 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NBZ7, Q8NBX3, Q9H5C2	Gene names	UXS1
Domain Architecture	No domain graphic available
Description	UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1).

LAX1_HUMAN
NC score	0.036725 (rank : 5)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWV1, Q6NSZ6, Q9NXB4	Gene names	LAX1, LAX
Domain Architecture	No domain graphic available
Description	Lymphocyte transmembrane adapter 1 (Membrane-associated adapter protein LAX) (Linker for activation of X cells).

RFX2_HUMAN
NC score	0.036027 (rank : 6)	θ value	3.0926 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	P48378	Gene names	RFX2
Domain Architecture
Description	DNA-binding protein RFX2.

CE005_HUMAN
NC score	0.030197 (rank : 7)	θ value	0.365318 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	213	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

UROL1_HUMAN
NC score	0.017672 (rank : 8)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	213	Shared Neighborhood Hits	2
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

SMUF1_HUMAN
NC score	0.011733 (rank : 9)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	135	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF1_MOUSE
NC score	0.011638 (rank : 10)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	142	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

CEND2_HUMAN
NC score	0.010102 (rank : 11)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	166	Shared Neighborhood Hits	3
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

PTN12_MOUSE
NC score	0.007049 (rank : 12)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN12_HUMAN
NC score	0.007030 (rank : 13)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

AMGO2_HUMAN
NC score	0.004752 (rank : 14)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	357	Shared Neighborhood Hits	2
SwissProt Accessions	Q86SJ2, Q7Z4A0, Q96CN8	Gene names	AMIGO2, ALI1
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 2 precursor (AMIGO-2) (Alivin-1) (Differentially expressed in gastric adenocarcinomas) (DEGA).