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Network neighborhood for query Sequence : GPR89_HUMAN

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GPR89_HUMAN
SwissProt Accessions	Q9Y302, Q53FQ9, Q5T2V8, Q5T5P5, Q659E2, Q6NVY5, Q9P0S4	Gene names	GPR89A, GPR89, SH120
Domain Architecture	No domain graphic available
Description	Protein GPR89A (Putative MAPK-activating protein PM01) (Putative NF- kappa-B-activating protein 90).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GPR89_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y302, Q53FQ9, Q5T2V8, Q5T5P5, Q659E2, Q6NVY5, Q9P0S4	Gene names	GPR89A, GPR89, SH120
Domain Architecture	No domain graphic available
Description	Protein GPR89A (Putative MAPK-activating protein PM01) (Putative NF- kappa-B-activating protein 90).

GPR89_MOUSE
θ value	0 (rank : 2)	NC score	0.998095 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BS95, Q9D455	Gene names	Gpr89a, Gpr89
Domain Architecture	No domain graphic available
Description	Protein GPR89A.

P2Y12_MOUSE
θ value	0.365318 (rank : 3)	NC score	0.025092 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	481	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CPV9	Gene names	P2ry12
Domain Architecture
Description	P2Y purinoceptor 12 (P2Y12).

OXGR1_HUMAN
θ value	1.81305 (rank : 4)	NC score	0.019764 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	542	Shared Neighborhood Hits	10
SwissProt Accessions	Q96P68, Q5T5A7, Q86TL1	Gene names	OXGR1, GPR80, GPR99, P2RY15, P2Y15
Domain Architecture
Description	2-oxoglutarate receptor 1 (Alpha-ketoglutarate receptor 1) (G-protein coupled receptor 80) (G-protein coupled receptor 99) (P2Y purinoceptor 15) (P2Y-like nucleotide receptor) (P2Y-like GPCR).

GPR34_MOUSE
θ value	3.0926 (rank : 5)	NC score	0.019115 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	717	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R1K6	Gene names	Gpr34
Domain Architecture
Description	Probable G-protein coupled receptor 34.

TM16C_HUMAN
θ value	3.0926 (rank : 6)	NC score	0.025527 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYT9	Gene names	TMEM16C, C11orf25
Domain Architecture
Description	Transmembrane protein 16C.

ADA1A_MOUSE
θ value	5.27518 (rank : 7)	NC score	0.006814 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	940	Shared Neighborhood Hits	9
SwissProt Accessions	P97718, O54913	Gene names	Adra1a, Adra1c
Domain Architecture
Description	Alpha-1A adrenergic receptor (Alpha 1A-adrenoceptor) (Alpha 1A- adrenoreceptor) (Alpha-1C adrenergic receptor).

CAC1B_HUMAN
θ value	5.27518 (rank : 8)	NC score	0.008237 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	257	Shared Neighborhood Hits	2
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

P2Y12_HUMAN
θ value	5.27518 (rank : 9)	NC score	0.020002 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	463	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H244, Q546J7	Gene names	P2RY12, HORK3
Domain Architecture
Description	P2Y purinoceptor 12 (P2Y12) (P2Y12 platelet ADP receptor) (P2Y(ADP)) (ADP-glucose receptor) (ADPG-R) (P2Y(AC)) (P2Y(cyc)) (P2T(AC)) (SP1999).

CCR8_MOUSE
θ value	6.88961 (rank : 10)	NC score	0.011966 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	822	Shared Neighborhood Hits	10
SwissProt Accessions	P56484	Gene names	Ccr8, Cmkbr8, Ter1
Domain Architecture
Description	C-C chemokine receptor type 8 (C-C CKR-8) (CC-CKR-8) (CCR-8).

GPR34_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.016919 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	695	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UPC5, O95853	Gene names	GPR34
Domain Architecture
Description	Probable G-protein coupled receptor 34.

PSN1_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.032543 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P49768, O95465, Q14762, Q15719, Q15720, Q96P33, Q9UIF0	Gene names	PSEN1, AD3, PS1, PSNL1
Domain Architecture
Description	Presenilin-1 (EC 3.4.23.-) (PS-1) (Protein S182) [Contains: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)].

PSN1_MOUSE
θ value	6.88961 (rank : 13)	NC score	0.032549 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	P49769, Q91WK6, Q9JLP9	Gene names	Psen1, Ad3h, Psnl1
Domain Architecture
Description	Presenilin-1 (EC 3.4.23.-) (PS-1) (Protein S182) [Contains: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)].

KIF2B_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.008158 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N4N8, Q96MA2, Q9BXG6	Gene names	KIF2B
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF2B.

P2RY5_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.013196 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	630	Shared Neighborhood Hits	10
SwissProt Accessions	P43657, O15133, Q3KPF5, Q5VW44, Q7Z3S0, Q7Z3S6	Gene names	P2RY5
Domain Architecture
Description	P2Y purinoceptor 5 (P2Y5) (Purinergic receptor 5) (RB intron encoded G-protein coupled receptor).

Hits sorted by NC score

GPR89_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y302, Q53FQ9, Q5T2V8, Q5T5P5, Q659E2, Q6NVY5, Q9P0S4	Gene names	GPR89A, GPR89, SH120
Domain Architecture	No domain graphic available
Description	Protein GPR89A (Putative MAPK-activating protein PM01) (Putative NF- kappa-B-activating protein 90).

GPR89_MOUSE
NC score	0.998095 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BS95, Q9D455	Gene names	Gpr89a, Gpr89
Domain Architecture	No domain graphic available
Description	Protein GPR89A.

PSN1_MOUSE
NC score	0.032549 (rank : 3)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	P49769, Q91WK6, Q9JLP9	Gene names	Psen1, Ad3h, Psnl1
Domain Architecture
Description	Presenilin-1 (EC 3.4.23.-) (PS-1) (Protein S182) [Contains: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)].

PSN1_HUMAN
NC score	0.032543 (rank : 4)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P49768, O95465, Q14762, Q15719, Q15720, Q96P33, Q9UIF0	Gene names	PSEN1, AD3, PS1, PSNL1
Domain Architecture
Description	Presenilin-1 (EC 3.4.23.-) (PS-1) (Protein S182) [Contains: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)].

TM16C_HUMAN
NC score	0.025527 (rank : 5)	θ value	3.0926 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYT9	Gene names	TMEM16C, C11orf25
Domain Architecture
Description	Transmembrane protein 16C.

P2Y12_MOUSE
NC score	0.025092 (rank : 6)	θ value	0.365318 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	481	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CPV9	Gene names	P2ry12
Domain Architecture
Description	P2Y purinoceptor 12 (P2Y12).

P2Y12_HUMAN
NC score	0.020002 (rank : 7)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	463	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H244, Q546J7	Gene names	P2RY12, HORK3
Domain Architecture
Description	P2Y purinoceptor 12 (P2Y12) (P2Y12 platelet ADP receptor) (P2Y(ADP)) (ADP-glucose receptor) (ADPG-R) (P2Y(AC)) (P2Y(cyc)) (P2T(AC)) (SP1999).

OXGR1_HUMAN
NC score	0.019764 (rank : 8)	θ value	1.81305 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	542	Shared Neighborhood Hits	10
SwissProt Accessions	Q96P68, Q5T5A7, Q86TL1	Gene names	OXGR1, GPR80, GPR99, P2RY15, P2Y15
Domain Architecture
Description	2-oxoglutarate receptor 1 (Alpha-ketoglutarate receptor 1) (G-protein coupled receptor 80) (G-protein coupled receptor 99) (P2Y purinoceptor 15) (P2Y-like nucleotide receptor) (P2Y-like GPCR).

GPR34_MOUSE
NC score	0.019115 (rank : 9)	θ value	3.0926 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	717	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R1K6	Gene names	Gpr34
Domain Architecture
Description	Probable G-protein coupled receptor 34.

GPR34_HUMAN
NC score	0.016919 (rank : 10)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	695	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UPC5, O95853	Gene names	GPR34
Domain Architecture
Description	Probable G-protein coupled receptor 34.

P2RY5_HUMAN
NC score	0.013196 (rank : 11)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	630	Shared Neighborhood Hits	10
SwissProt Accessions	P43657, O15133, Q3KPF5, Q5VW44, Q7Z3S0, Q7Z3S6	Gene names	P2RY5
Domain Architecture
Description	P2Y purinoceptor 5 (P2Y5) (Purinergic receptor 5) (RB intron encoded G-protein coupled receptor).

CCR8_MOUSE
NC score	0.011966 (rank : 12)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	822	Shared Neighborhood Hits	10
SwissProt Accessions	P56484	Gene names	Ccr8, Cmkbr8, Ter1
Domain Architecture
Description	C-C chemokine receptor type 8 (C-C CKR-8) (CC-CKR-8) (CCR-8).

CAC1B_HUMAN
NC score	0.008237 (rank : 13)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	257	Shared Neighborhood Hits	2
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

KIF2B_HUMAN
NC score	0.008158 (rank : 14)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N4N8, Q96MA2, Q9BXG6	Gene names	KIF2B
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF2B.

ADA1A_MOUSE
NC score	0.006814 (rank : 15)	θ value	5.27518 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	940	Shared Neighborhood Hits	9
SwissProt Accessions	P97718, O54913	Gene names	Adra1a, Adra1c
Domain Architecture
Description	Alpha-1A adrenergic receptor (Alpha 1A-adrenoceptor) (Alpha 1A- adrenoreceptor) (Alpha-1C adrenergic receptor).