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Network neighborhood for query Sequence : FANCA_HUMAN

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FANCA_HUMAN
SwissProt Accessions	O15360, O75266, Q6PL10, Q92497, Q96H18, Q9UEA5, Q9UEL8, Q9UEL9, Q9UPK3, Q9Y6M2	Gene names	FANCA, FAA
Domain Architecture
Description	Fanconi anemia group A protein (Protein FACA).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FANCA_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	O15360, O75266, Q6PL10, Q92497, Q96H18, Q9UEA5, Q9UEL8, Q9UEL9, Q9UPK3, Q9Y6M2	Gene names	FANCA, FAA
Domain Architecture
Description	Fanconi anemia group A protein (Protein FACA).

FANCA_MOUSE
θ value	0 (rank : 2)	NC score	0.984257 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JL70, Q9ESU9, Q9ESV3, Q9ET44, Q9JL64, Q9JL65, Q9JL66, Q9JL67, Q9JL68, Q9JL69	Gene names	Fanca
Domain Architecture	No domain graphic available
Description	Fanconi anemia group A protein homolog (Protein FACA).

NU160_HUMAN
θ value	1.81305 (rank : 3)	NC score	0.030309 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q12769, Q96GB3, Q9H660	Gene names	NUP160, KIAA0197, NUP120
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup160 (Nucleoporin Nup160) (160 kDa nucleoporin).

SPTB2_HUMAN
θ value	1.81305 (rank : 4)	NC score	0.013433 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	748	Shared Neighborhood Hits	3
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_MOUSE
θ value	1.81305 (rank : 5)	NC score	0.013372 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	770	Shared Neighborhood Hits	3
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

PTPRK_MOUSE
θ value	3.0926 (rank : 6)	NC score	0.007386 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	223	Shared Neighborhood Hits	2
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

SSFA2_MOUSE
θ value	4.03905 (rank : 7)	NC score	0.030243 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q922B9, Q8VEF7	Gene names	Ssfa2
Domain Architecture	No domain graphic available
Description	Sperm-specific antigen 2.

MIB2_HUMAN
θ value	5.27518 (rank : 8)	NC score	0.006625 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	438	Shared Neighborhood Hits	3
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

COG8_HUMAN
θ value	6.88961 (rank : 9)	NC score	0.017859 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q96MW5, Q8WVV6, Q9H6F8	Gene names	COG8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

FGD3_MOUSE
θ value	6.88961 (rank : 10)	NC score	0.006959 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	257	Shared Neighborhood Hits	2
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

PDP1_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.020642 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P0J1, Q5U5K1	Gene names	PDP1, PDP, PPM2C
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]]-phosphatase 1, mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1) (Protein phosphatase 2C).

PDP1_MOUSE
θ value	6.88961 (rank : 12)	NC score	0.020574 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UV70	Gene names	Pdp1, Ppm2c
Domain Architecture	No domain graphic available
Description	[Pyruvate dehydrogenase [lipoamide]]-phosphatase 1, mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1) (Protein phosphatase 2C).

TCF8_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.001989 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	1057	Shared Neighborhood Hits	3
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

AKA12_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.009458 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	825	Shared Neighborhood Hits	3
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

CE152_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.004408 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	976	Shared Neighborhood Hits	2
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

GLSL_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.009514 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	211	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

ITIH2_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.008637 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P19823, Q14659, Q15484	Gene names	ITIH2, IGHEP2
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H2 precursor (ITI heavy chain H2) (Inter-alpha-inhibitor heavy chain 2) (Inter-alpha-trypsin inhibitor complex component II) (Serum-derived hyaluronan-associated protein) (SHAP).

O13C4_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.000169 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	721	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NGS5, Q96R41	Gene names	OR13C4
Domain Architecture
Description	Olfactory receptor 13C4.

Hits sorted by NC score

FANCA_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	O15360, O75266, Q6PL10, Q92497, Q96H18, Q9UEA5, Q9UEL8, Q9UEL9, Q9UPK3, Q9Y6M2	Gene names	FANCA, FAA
Domain Architecture
Description	Fanconi anemia group A protein (Protein FACA).

FANCA_MOUSE
NC score	0.984257 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JL70, Q9ESU9, Q9ESV3, Q9ET44, Q9JL64, Q9JL65, Q9JL66, Q9JL67, Q9JL68, Q9JL69	Gene names	Fanca
Domain Architecture	No domain graphic available
Description	Fanconi anemia group A protein homolog (Protein FACA).

NU160_HUMAN
NC score	0.030309 (rank : 3)	θ value	1.81305 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q12769, Q96GB3, Q9H660	Gene names	NUP160, KIAA0197, NUP120
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup160 (Nucleoporin Nup160) (160 kDa nucleoporin).

SSFA2_MOUSE
NC score	0.030243 (rank : 4)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q922B9, Q8VEF7	Gene names	Ssfa2
Domain Architecture	No domain graphic available
Description	Sperm-specific antigen 2.

PDP1_HUMAN
NC score	0.020642 (rank : 5)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P0J1, Q5U5K1	Gene names	PDP1, PDP, PPM2C
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]]-phosphatase 1, mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1) (Protein phosphatase 2C).

PDP1_MOUSE
NC score	0.020574 (rank : 6)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UV70	Gene names	Pdp1, Ppm2c
Domain Architecture	No domain graphic available
Description	[Pyruvate dehydrogenase [lipoamide]]-phosphatase 1, mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1) (Protein phosphatase 2C).

COG8_HUMAN
NC score	0.017859 (rank : 7)	θ value	6.88961 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q96MW5, Q8WVV6, Q9H6F8	Gene names	COG8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

SPTB2_HUMAN
NC score	0.013433 (rank : 8)	θ value	1.81305 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	748	Shared Neighborhood Hits	3
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_MOUSE
NC score	0.013372 (rank : 9)	θ value	1.81305 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	770	Shared Neighborhood Hits	3
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

GLSL_HUMAN
NC score	0.009514 (rank : 10)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	211	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

AKA12_HUMAN
NC score	0.009458 (rank : 11)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	825	Shared Neighborhood Hits	3
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

ITIH2_HUMAN
NC score	0.008637 (rank : 12)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P19823, Q14659, Q15484	Gene names	ITIH2, IGHEP2
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H2 precursor (ITI heavy chain H2) (Inter-alpha-inhibitor heavy chain 2) (Inter-alpha-trypsin inhibitor complex component II) (Serum-derived hyaluronan-associated protein) (SHAP).

PTPRK_MOUSE
NC score	0.007386 (rank : 13)	θ value	3.0926 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	223	Shared Neighborhood Hits	2
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

FGD3_MOUSE
NC score	0.006959 (rank : 14)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	257	Shared Neighborhood Hits	2
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

MIB2_HUMAN
NC score	0.006625 (rank : 15)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	438	Shared Neighborhood Hits	3
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

CE152_HUMAN
NC score	0.004408 (rank : 16)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	976	Shared Neighborhood Hits	2
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

TCF8_HUMAN
NC score	0.001989 (rank : 17)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	1057	Shared Neighborhood Hits	3
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

O13C4_HUMAN
NC score	0.000169 (rank : 18)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	721	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NGS5, Q96R41	Gene names	OR13C4
Domain Architecture
Description	Olfactory receptor 13C4.